JP2020502198A5 - - Google Patents

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Publication number
JP2020502198A5
JP2020502198A5 JP2019533195A JP2019533195A JP2020502198A5 JP 2020502198 A5 JP2020502198 A5 JP 2020502198A5 JP 2019533195 A JP2019533195 A JP 2019533195A JP 2019533195 A JP2019533195 A JP 2019533195A JP 2020502198 A5 JP2020502198 A5 JP 2020502198A5
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JP
Japan
Prior art keywords
residue
seq
substitution
composition according
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019533195A
Other languages
English (en)
Japanese (ja)
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JP2020502198A (ja
JP7290568B2 (ja
Filing date
Publication date
Priority claimed from GBGB1621782.0A external-priority patent/GB201621782D0/en
Priority claimed from GBGB1702338.3A external-priority patent/GB201702338D0/en
Priority claimed from GBGB1702339.1A external-priority patent/GB201702339D0/en
Priority claimed from GBGB1703071.9A external-priority patent/GB201703071D0/en
Priority claimed from US15/480,525 external-priority patent/US10604576B2/en
Priority claimed from PCT/GB2017/051795 external-priority patent/WO2017220989A1/en
Priority claimed from GBGB1709818.7A external-priority patent/GB201709818D0/en
Priority claimed from TW106126908A external-priority patent/TWI760352B/zh
Priority claimed from PCT/GB2017/052352 external-priority patent/WO2018029474A2/en
Application filed filed Critical
Priority claimed from PCT/GB2017/053826 external-priority patent/WO2018115859A1/en
Publication of JP2020502198A publication Critical patent/JP2020502198A/ja
Publication of JP2020502198A5 publication Critical patent/JP2020502198A5/ja
Priority to JP2023016174A priority Critical patent/JP7750887B2/ja
Application granted granted Critical
Publication of JP7290568B2 publication Critical patent/JP7290568B2/ja
Priority to JP2025157613A priority patent/JP2026001069A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019533195A 2016-12-20 2017-12-19 癌免疫療法のための併用療法での多重特異性抗体 Active JP7290568B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023016174A JP7750887B2 (ja) 2016-12-20 2023-02-06 癌免疫療法のための併用療法での多重特異性抗体
JP2025157613A JP2026001069A (ja) 2016-12-20 2025-09-24 癌免疫療法のための併用療法での多重特異性抗体

Applications Claiming Priority (29)

Application Number Priority Date Filing Date Title
GB1621782.0 2016-12-20
GBGB1621782.0A GB201621782D0 (en) 2016-12-20 2016-12-20 Antibodies and immunocytokines PD-L1 specific antibodies and PD-L1 specific immunocytokines
GB1702338.3 2017-02-13
GB1702339.1 2017-02-13
GBGB1702339.1A GB201702339D0 (en) 2017-02-13 2017-02-13 Antibodies and immunocytokines PD-L1 Specific antiboies and PD-L1 Specific immunocytokines
GBGB1702338.3A GB201702338D0 (en) 2017-02-13 2017-02-13 Antibodies and immunocytokines PD-L1 specific antibodies and specific immunocytokines
GBGB1703071.9A GB201703071D0 (en) 2017-02-24 2017-02-24 Antibodies
GB1703071.9 2017-02-24
US15/480,525 2017-04-06
US15/480,525 US10604576B2 (en) 2016-06-20 2017-04-06 Antibodies and immunocytokines
TW106120563 2017-06-20
PCT/GB2017/051795 WO2017220989A1 (en) 2016-06-20 2017-06-20 Anti-pd-l1 and il-2 cytokines
GBGB1709818.7A GB201709818D0 (en) 2017-06-20 2017-06-20 Antibodies
TW106120564A TWI640536B (zh) 2016-06-20 2017-06-20 抗體
PCT/GB2017/051796 WO2017220990A1 (en) 2016-06-20 2017-06-20 Anti-pd-l1 antibodies
GBPCT/GB2017/051796 2017-06-20
TW106120564 2017-06-20
GB1709818.7 2017-06-20
TW106120563A TW201803905A (zh) 2016-06-20 2017-06-20 用於免疫腫瘤學之多重專一性抗體
PCT/GB2017/051794 WO2017220988A1 (en) 2016-06-20 2017-06-20 Multispecific antibodies for immuno-oncology
GBPCT/GB2017/051795 2017-06-20
TW106120562 2017-06-20
TW106120562A TWI784957B (zh) 2016-06-20 2017-06-20 免疫細胞介素
GBPCT/GB2017/051794 2017-06-20
PCT/GB2017/052352 WO2018029474A2 (en) 2016-08-09 2017-08-09 Anti-icos antibodies
GBPCT/GB2017/052352 2017-08-09
TW106126908A TWI760352B (zh) 2016-08-09 2017-08-09 抗icos抗體
TW106126908 2017-08-09
PCT/GB2017/053826 WO2018115859A1 (en) 2016-12-20 2017-12-19 Multispecific antibody with combination therapy for immuno-oncology

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023016174A Division JP7750887B2 (ja) 2016-12-20 2023-02-06 癌免疫療法のための併用療法での多重特異性抗体

Publications (3)

Publication Number Publication Date
JP2020502198A JP2020502198A (ja) 2020-01-23
JP2020502198A5 true JP2020502198A5 (enExample) 2021-01-28
JP7290568B2 JP7290568B2 (ja) 2023-06-13

Family

ID=61192960

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019533195A Active JP7290568B2 (ja) 2016-12-20 2017-12-19 癌免疫療法のための併用療法での多重特異性抗体
JP2023016174A Active JP7750887B2 (ja) 2016-12-20 2023-02-06 癌免疫療法のための併用療法での多重特異性抗体
JP2025157613A Pending JP2026001069A (ja) 2016-12-20 2025-09-24 癌免疫療法のための併用療法での多重特異性抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023016174A Active JP7750887B2 (ja) 2016-12-20 2023-02-06 癌免疫療法のための併用療法での多重特異性抗体
JP2025157613A Pending JP2026001069A (ja) 2016-12-20 2025-09-24 癌免疫療法のための併用療法での多重特異性抗体

Country Status (3)

Country Link
US (2) US20200190191A1 (enExample)
EP (1) EP3559041A1 (enExample)
JP (3) JP7290568B2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3497128A2 (en) * 2016-08-09 2019-06-19 Kymab Limited Anti-icos antibodies
WO2019025545A1 (en) 2017-08-04 2019-02-07 Genmab A/S BINDING AGENTS BINDING TO PD-L1 AND CD137 AND THEIR USE
EP3728314A1 (en) * 2017-12-19 2020-10-28 Kymab Limited Bispecific antibody for icos and pd-l1
GB201721338D0 (en) 2017-12-19 2018-01-31 Kymab Ltd Anti-icos Antibodies
AU2021257570A1 (en) * 2020-04-14 2022-11-03 Glaxosmithkline Intellectual Property Development Limited Combination treatment for cancer
CA3171557A1 (en) * 2020-04-14 2021-10-21 Marc S. BALLAS Combination treatment for cancer involving anti-icos and anti-pd1 antibodies, optionally further involving anti-tim3 antibodies
WO2022081841A1 (en) * 2020-10-16 2022-04-21 Fred Hutchinson Cancer Research Center Specific targeting of tumor-infiltrating regulatory t cells (tregs) using icos and il-1r1
CA3219336A1 (en) * 2021-05-18 2022-11-24 Kymab Limited Uses of anti-icos antibodies
US20250002600A1 (en) * 2021-10-06 2025-01-02 Genmab A/S Multispecific binding agents against pd-l1 and cd137 in combination therapy
US20250340641A1 (en) * 2022-05-18 2025-11-06 Kymab Limited Uses of anti-icos antibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2482849B1 (en) * 2009-09-30 2018-06-06 Memorial Sloan-Kettering Cancer Center Combination immunotherapy for the treatment of cancer
KR20170129902A (ko) * 2015-03-23 2017-11-27 조운스 테라퓨틱스, 인크. Icos에 대한 항체
EP3497128A2 (en) * 2016-08-09 2019-06-19 Kymab Limited Anti-icos antibodies
EP3728314A1 (en) * 2017-12-19 2020-10-28 Kymab Limited Bispecific antibody for icos and pd-l1

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