JP2013513135A5 - - Google Patents
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- Publication number
- JP2013513135A5 JP2013513135A5 JP2012543176A JP2012543176A JP2013513135A5 JP 2013513135 A5 JP2013513135 A5 JP 2013513135A5 JP 2012543176 A JP2012543176 A JP 2012543176A JP 2012543176 A JP2012543176 A JP 2012543176A JP 2013513135 A5 JP2013513135 A5 JP 2013513135A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrophilic polymer
- oxazolin
- contact lens
- layer
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 claims description 12
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 6
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 claims description 6
- 229910052739 hydrogen Inorganic materials 0.000 claims description 4
- 239000001257 hydrogen Substances 0.000 claims description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 2
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 claims description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 2
- 125000002947 alkylene group Chemical group 0.000 claims description 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 2
- 150000002431 hydrogen Chemical class 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 229920001477 hydrophilic polymer Polymers 0.000 claims 21
- 238000000034 method Methods 0.000 claims 16
- 239000011248 coating agent Substances 0.000 claims 15
- 238000000576 coating method Methods 0.000 claims 15
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 11
- 239000000178 monomer Substances 0.000 claims 9
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 9
- 229920002554 vinyl polymer Polymers 0.000 claims 9
- HONIICLYMWZJFZ-UHFFFAOYSA-O azetidin-1-ium Chemical compound C1C[NH2+]C1 HONIICLYMWZJFZ-UHFFFAOYSA-O 0.000 claims 7
- IEJPPSMHUUQABK-UHFFFAOYSA-N 2,4-diphenyl-4h-1,3-oxazol-5-one Chemical compound O=C1OC(C=2C=CC=CC=2)=NC1C1=CC=CC=C1 IEJPPSMHUUQABK-UHFFFAOYSA-N 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- 229920001296 polysiloxane Polymers 0.000 claims 6
- 239000000017 hydrogel Substances 0.000 claims 5
- 229920002518 Polyallylamine hydrochloride Polymers 0.000 claims 4
- 229920001519 homopolymer Polymers 0.000 claims 4
- 229920001577 copolymer Polymers 0.000 claims 3
- 239000003960 organic solvent Substances 0.000 claims 3
- DQRFCVHLNUNVPL-UHFFFAOYSA-N 2h-1,3-oxazol-5-one Chemical compound O=C1OCN=C1 DQRFCVHLNUNVPL-UHFFFAOYSA-N 0.000 claims 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 229920002873 Polyethylenimine Polymers 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 229920002674 hyaluronan Polymers 0.000 claims 2
- 229960003160 hyaluronic acid Drugs 0.000 claims 2
- -1 hyaluronic acid aldehyde Chemical class 0.000 claims 2
- 239000004584 polyacrylic acid Substances 0.000 claims 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- FPPNONHSLAHRLW-UHFFFAOYSA-N 2-ethenyl-4,4-diethyl-1,3-oxazol-5-one Chemical compound CCC1(CC)N=C(C=C)OC1=O FPPNONHSLAHRLW-UHFFFAOYSA-N 0.000 claims 1
- QKPKBBFSFQAMIY-UHFFFAOYSA-N 2-ethenyl-4,4-dimethyl-1,3-oxazol-5-one Chemical group CC1(C)N=C(C=C)OC1=O QKPKBBFSFQAMIY-UHFFFAOYSA-N 0.000 claims 1
- DMDNNZDDQOLFPX-UHFFFAOYSA-N 2-ethenyl-4-ethyl-4-methyl-1,3-oxazol-5-one Chemical compound CCC1(C)N=C(C=C)OC1=O DMDNNZDDQOLFPX-UHFFFAOYSA-N 0.000 claims 1
- SQZSACNFCGPRRH-UHFFFAOYSA-N 2-ethenyl-4-methyl-4-nonyl-1,3-oxazol-5-one Chemical compound CCCCCCCCCC1(C)N=C(C=C)OC1=O SQZSACNFCGPRRH-UHFFFAOYSA-N 0.000 claims 1
- HQGFOVSJARUBLL-UHFFFAOYSA-N 4,4-dibutyl-2-ethenyl-1,3-oxazol-5-one Chemical compound CCCCC1(CCCC)N=C(C=C)OC1=O HQGFOVSJARUBLL-UHFFFAOYSA-N 0.000 claims 1
- MUWZQYSJSCDUDT-UHFFFAOYSA-N 4,4-dimethyl-2-prop-1-en-2-yl-1,3-oxazol-5-one Chemical compound CC(=C)C1=NC(C)(C)C(=O)O1 MUWZQYSJSCDUDT-UHFFFAOYSA-N 0.000 claims 1
- HIPFXTMAGCIYHP-UHFFFAOYSA-N 4,4-diphenyl-2-prop-1-en-2-yl-1,3-oxazol-5-one Chemical compound O=C1OC(C(=C)C)=NC1(C=1C=CC=CC=1)C1=CC=CC=C1 HIPFXTMAGCIYHP-UHFFFAOYSA-N 0.000 claims 1
- PAWWCZYDPHQUEE-UHFFFAOYSA-N 4-benzyl-4-methyl-2-prop-1-en-2-yl-1,3-oxazol-5-one Chemical compound O=C1OC(C(=C)C)=NC1(C)CC1=CC=CC=C1 PAWWCZYDPHQUEE-UHFFFAOYSA-N 0.000 claims 1
- LEPHQAPDYFHROC-UHFFFAOYSA-N 4-butyl-4-methyl-2-prop-1-en-2-yl-1,3-oxazol-5-one Chemical compound CCCCC1(C)N=C(C(C)=C)OC1=O LEPHQAPDYFHROC-UHFFFAOYSA-N 0.000 claims 1
- BIJRDVLWMJIKTR-UHFFFAOYSA-N 4-dodecyl-4-methyl-2-prop-1-en-2-yl-1,3-oxazol-5-one Chemical compound CCCCCCCCCCCCC1(C)N=C(C(C)=C)OC1=O BIJRDVLWMJIKTR-UHFFFAOYSA-N 0.000 claims 1
- URDUKROSCCHPQL-UHFFFAOYSA-N 4-methyl-4-phenyl-2-prop-1-en-2-yl-1,3-oxazol-5-one Chemical compound O=C1OC(C(=C)C)=NC1(C)C1=CC=CC=C1 URDUKROSCCHPQL-UHFFFAOYSA-N 0.000 claims 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Natural products OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 1
- 229920002845 Poly(methacrylic acid) Polymers 0.000 claims 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000003926 acrylamides Chemical class 0.000 claims 1
- 125000003172 aldehyde group Chemical group 0.000 claims 1
- 125000004103 aminoalkyl group Chemical group 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 239000001530 fumaric acid Substances 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 1
- 239000011976 maleic acid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 229920003145 methacrylic acid copolymer Polymers 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26746909P | 2009-12-08 | 2009-12-08 | |
| US61/267,469 | 2009-12-08 | ||
| PCT/US2010/059022 WO2011071791A1 (en) | 2009-12-08 | 2010-12-06 | A silicone hydrogel lens with a covalently attached coating |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013513135A JP2013513135A (ja) | 2013-04-18 |
| JP2013513135A5 true JP2013513135A5 (https=) | 2015-03-05 |
| JP5877793B2 JP5877793B2 (ja) | 2016-03-08 |
Family
ID=44081708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543176A Active JP5877793B2 (ja) | 2009-12-08 | 2010-12-06 | 共有結合コーティングを有するシリコーンハイドロゲルレンズ |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8557334B2 (https=) |
| EP (1) | EP2510052B1 (https=) |
| JP (1) | JP5877793B2 (https=) |
| CA (1) | CA2777961C (https=) |
| TW (1) | TWI483996B (https=) |
| WO (1) | WO2011071791A1 (https=) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8470906B2 (en) | 2008-09-30 | 2013-06-25 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels having improved hydrolytic stability |
| US20130203812A1 (en) | 2008-09-30 | 2013-08-08 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels comprising pharmaceutical and/or nutriceutical components and having improved hydrolytic stability |
| US9522980B2 (en) | 2010-05-06 | 2016-12-20 | Johnson & Johnson Vision Care, Inc. | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same |
| US8480227B2 (en) | 2010-07-30 | 2013-07-09 | Novartis Ag | Silicone hydrogel lenses with water-rich surfaces |
| WO2012130956A1 (en) * | 2011-04-01 | 2012-10-04 | Novartis Ag | Composition for forming a contact lens |
| US9170349B2 (en) | 2011-05-04 | 2015-10-27 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| US20130203813A1 (en) | 2011-05-04 | 2013-08-08 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| HUE029018T2 (en) * | 2011-10-12 | 2017-02-28 | Novartis Ag | A method for producing UV absorbing contact lenses by coating |
| US20130323295A1 (en) * | 2011-12-08 | 2013-12-05 | Johnson & Johnson Vision Care, Inc. | Monomer systems with dispersed silicone-based engineered particles |
| CA2857181C (en) | 2011-12-08 | 2016-10-11 | Novartis Ag | Contact lenses with enzymatically degradable coatings thereon |
| CN107522880B (zh) * | 2012-01-25 | 2020-07-24 | 阿克伦大学 | 水凝胶及其制备方法 |
| US9297929B2 (en) | 2012-05-25 | 2016-03-29 | Johnson & Johnson Vision Care, Inc. | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers |
| US10073192B2 (en) | 2012-05-25 | 2018-09-11 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US9244196B2 (en) | 2012-05-25 | 2016-01-26 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US9422447B2 (en) * | 2012-06-14 | 2016-08-23 | Novartis Ag | Azetidinium-containing copolymers and uses thereof |
| US9395468B2 (en) | 2012-08-27 | 2016-07-19 | Ocular Dynamics, Llc | Contact lens with a hydrophilic layer |
| EP2931504B1 (en) * | 2012-12-11 | 2018-09-26 | Novartis AG | Method for applying a coating onto a silicone hydrogel lens |
| HUE031702T2 (en) | 2012-12-17 | 2017-07-28 | Novartis Ag | A method for producing improved UV absorbing ophthalmic lenses |
| US9161598B2 (en) * | 2012-12-21 | 2015-10-20 | Coopervision International Holding Company, Lp | Ophthalmic devices for delivery of beneficial agents |
| KR101640725B1 (ko) * | 2013-04-30 | 2016-07-18 | 쿠퍼비젼 인터내셔날 홀딩 캄파니, 엘피 | 1급 아민-함유 실리콘 히드로겔 콘택트 렌즈, 및 관련 조성물 및 방법 |
| JP6257633B2 (ja) | 2013-08-27 | 2018-01-10 | 国立大学法人大阪大学 | 材料界面での化学的結合により接合した接合体及びその接合方法 |
| CA2923350A1 (en) * | 2013-09-12 | 2015-03-19 | Dsm Ip Assets B.V. | Ocular device |
| US9568645B2 (en) | 2013-09-30 | 2017-02-14 | Novartis Ag | Silicone hydrogel lenses with relatively-long thermal stability |
| WO2015048035A1 (en) | 2013-09-30 | 2015-04-02 | Novartis Ag | Method for making uv-absorbing ophthalmic lenses |
| EP3062979B1 (en) | 2013-10-31 | 2018-08-29 | Novartis AG | Method for producing ophthalmic lenses |
| AU2014348502B2 (en) * | 2013-11-15 | 2019-08-15 | Tangible Science, Inc. | Contact lens with a hydrophilic layer |
| MY183117A (en) | 2013-12-13 | 2021-02-15 | Alcon Inc | Method for making contact lenses |
| HUE038809T2 (hu) | 2013-12-17 | 2018-11-28 | Novartis Ag | Térhálósított hidrofíl bevonattal ellátott szilikon hidrogél lencse |
| WO2015164582A1 (en) | 2014-04-25 | 2015-10-29 | Novartis Ag | Hydrophilized carbosiloxane vinylic monomers |
| KR101775358B1 (ko) * | 2014-05-09 | 2017-09-07 | 주식회사 인터로조 | 습윤성 표면을 가지는 하이드로겔 콘택트렌즈 및 그 제조방법 |
| TWI511871B (zh) * | 2014-05-23 | 2015-12-11 | Benq Materials Corp | 製備彩色隱形眼鏡之方法 |
| CN106661224B (zh) * | 2014-08-26 | 2019-10-11 | 诺华股份有限公司 | 聚(噁唑啉-共-乙烯亚胺)-表氯醇共聚物及其用途 |
| MY183678A (en) | 2014-08-26 | 2021-03-08 | Alcon Inc | Method for applying stable coating on silicone hydrogel contact lenses |
| AU2015321646B2 (en) | 2014-09-26 | 2017-11-30 | Alcon Inc. | Polymerizable polysiloxanes with hydrophilic substituents |
| CN107206119B (zh) | 2014-12-09 | 2021-01-29 | 实体科学公司 | 具有生物相容性层的医疗设备涂层 |
| ES2837120T3 (es) | 2015-03-11 | 2021-06-29 | Univ Florida | Control del tamaño de malla de lubricación en hidrogeles gemini |
| JP6595120B2 (ja) | 2015-12-03 | 2019-10-23 | ノバルティス アーゲー | コンタクトレンズパッケージング溶液 |
| WO2017103792A1 (en) | 2015-12-15 | 2017-06-22 | Novartis Ag | Amphiphilic branched polydiorganosiloxane macromers |
| KR102604468B1 (ko) | 2015-12-15 | 2023-11-22 | 알콘 인코포레이티드 | 실리콘 하이드로겔 콘택트 렌즈 상에 안정한 코팅을 적용하기 위한 방법 |
| EP3390498B1 (en) | 2015-12-15 | 2021-05-26 | Alcon Inc. | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof |
| EP3390497B1 (en) | 2015-12-15 | 2021-01-20 | Alcon Inc. | Polymerizable polysiloxanes with hydrophilic substituents |
| JP7038111B2 (ja) | 2016-09-20 | 2022-03-17 | アルコン インク． | ヒドロゲルコンタクトレンズ上に潤滑性コーティングを有するヒドロゲルコンタクトレンズ |
| EP3516429B1 (en) * | 2016-09-20 | 2021-02-17 | Alcon Inc. | Colored hydrogel contact lenses with lubricious coating thereon |
| WO2018069816A1 (en) | 2016-10-11 | 2018-04-19 | Novartis Ag | Polymerizable polydimethylsiloxane-polyoxyalkylene block copolymers |
| WO2018069815A1 (en) | 2016-10-11 | 2018-04-19 | Novartis Ag | Chain-extended polydimethylsiloxane vinylic crosslinkers and uses thereof |
| US10527757B2 (en) | 2016-10-26 | 2020-01-07 | Novartis Ag | Amphiphilic branched polydiorganosiloxane macromers |
| WO2018212063A1 (ja) * | 2017-05-19 | 2018-11-22 | 東レ株式会社 | コンタクトレンズ用組成物、およびコンタクトレンズとその製造方法 |
| WO2018224974A1 (en) | 2017-06-07 | 2018-12-13 | Novartis Ag | Method for producing silicone hydrogel contact lenses |
| EP4481478A3 (en) | 2017-06-07 | 2025-03-26 | Alcon Inc. | Silicone hydrogel contact lenses |
| WO2018224975A1 (en) | 2017-06-07 | 2018-12-13 | Novartis Ag | Silicone hydrogel contact lenses |
| CN117492228A (zh) | 2017-12-13 | 2024-02-02 | 爱尔康公司 | 周抛和月抛水梯度接触镜片 |
| US11359156B2 (en) | 2019-10-21 | 2022-06-14 | Biocoat, Inc. | UV cure basecoatings for medical devices |
| WO2021081036A1 (en) * | 2019-10-21 | 2021-04-29 | Biocoat, Inc. | Uv cure coatings for medical devices |
| US12037560B2 (en) | 2019-10-21 | 2024-07-16 | Biocoat, Incorporated | UV cure topcoatings for medical devices |
| US11609438B2 (en) * | 2019-10-31 | 2023-03-21 | Menicon Singapore Pte Ltd. | Ocular lens with friction control structures |
| HUE069794T2 (hu) | 2019-11-04 | 2025-04-28 | Alcon Inc | Eljárás különbözõ puhaságú felületekkel rendelkezõ kontaktlencsék elõállítására |
| CN112812201B (zh) * | 2019-11-18 | 2023-06-16 | 孛朗孚(杭州)生物科技有限公司 | 巯基改性透明质酸及其制备方法和用途 |
| US12214146B2 (en) | 2019-12-11 | 2025-02-04 | Biocoat, Incorporated | Controlled release of a hydrophilic agent from a coated surface |
| KR20250007692A (ko) | 2019-12-16 | 2025-01-14 | 알콘 인코포레이티드 | 습윤성 실리콘 히드로겔 콘택트 렌즈 |
| EP4146461B1 (en) | 2020-05-07 | 2024-03-13 | Alcon Inc. | Method for producing silicone hydrogel contact lenses |
| EP4158392A1 (en) | 2020-06-02 | 2023-04-05 | Alcon Inc. | Method for making photochromic contact lenses |
| WO2022023966A1 (en) | 2020-07-28 | 2022-02-03 | Alcon Inc. | Contact lenses with softer lens surfaces |
| US11945181B2 (en) | 2020-10-28 | 2024-04-02 | Alcon Inc. | Method for making photochromic contact lenses |
| EP4240578B1 (en) | 2020-11-04 | 2024-12-18 | Alcon Inc. | Method for making photochromic contact lenses |
| HUE069913T2 (hu) | 2020-11-04 | 2025-04-28 | Alcon Inc | Eljárás fotokróm kontaktlencsék elõállítására |
| EP4304842B1 (en) | 2021-03-08 | 2026-05-06 | Alcon Inc. | Method for making photofunctional contact lenses |
| KR20230144634A (ko) | 2021-04-01 | 2023-10-16 | 알콘 인코포레이티드 | 광변색성 콘택트 렌즈의 제조 방법 |
| TWI885246B (zh) * | 2021-04-16 | 2025-06-01 | 晶碩光學股份有限公司 | 隱形眼鏡及其製造方法 |
| CN118119593A (zh) | 2021-07-13 | 2024-05-31 | 生物涂层有限公司 | 多官能交联剂：化合物、组合物和其产物 |
| TW202406726A (zh) | 2022-04-28 | 2024-02-16 | 瑞士商愛爾康公司 | 用於製造ｕｖ吸收性和ｈｅｖｌ吸收性眼科鏡片之方法 |
| US20230350100A1 (en) | 2022-04-29 | 2023-11-02 | Alcon Inc. | Method for making silicone hydrogel contact lenses |
| EP4529621A1 (en) | 2022-05-23 | 2025-04-02 | Alcon Inc. | Uv/hevl-filtering contact lenses |
| TW202406713A (zh) | 2022-05-23 | 2024-02-16 | 瑞士商愛爾康公司 | 用於製造ｈｅｖｌ過濾性接觸鏡片之方法 |
| JP2023178249A (ja) * | 2022-06-02 | 2023-12-14 | 日油株式会社 | コーティング層を有するソフトコンタクトレンズ |
| JP2025525733A (ja) | 2022-08-17 | 2025-08-07 | アルコン インク． | ハイドロゲルコーティングをその上に有するコンタクトレンズ |
| CN120418072A (zh) | 2023-02-02 | 2025-08-01 | 爱尔康公司 | 水梯度硅氧烷水凝胶隐形眼镜 |
| EP4713721A1 (en) | 2023-05-18 | 2026-03-25 | Alcon Inc. | Uv/hevl-filtering silicone hydrogel contact lenses |
| CN121443681A (zh) | 2023-08-07 | 2026-01-30 | 爱尔康公司 | Uv/hevl过滤性硅氧烷水凝胶隐形眼镜 |
| WO2025243221A1 (en) | 2024-05-22 | 2025-11-27 | Alcon Inc. | Reactive hevl-absorbing dyes |
| US20250362530A1 (en) | 2024-05-22 | 2025-11-27 | Alcon Inc. | Method for making centrally colored contact lenses |
| US20250361401A1 (en) | 2024-05-22 | 2025-11-27 | Alcon Inc. | Reactive dyes |
Family Cites Families (112)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3488327A (en) | 1967-06-30 | 1970-01-06 | Roehm & Haas Gmbh | Preparation of coating materials |
| DE1745348A1 (de) | 1967-12-01 | 1971-09-09 | Roehm Gmbh | Azlactongruppen enthaltende Mischpolymerisate |
| US3598790A (en) | 1966-07-01 | 1971-08-10 | Roehm & Haas Gmbh | Azlactone copolymers |
| US4343927A (en) | 1976-11-08 | 1982-08-10 | Chang Sing Hsiung | Hydrophilic, soft and oxygen permeable copolymer compositions |
| US4182822A (en) | 1976-11-08 | 1980-01-08 | Chang Sing Hsiung | Hydrophilic, soft and oxygen permeable copolymer composition |
| US4136250A (en) | 1977-07-20 | 1979-01-23 | Ciba-Geigy Corporation | Polysiloxane hydrogels |
| US4153641A (en) | 1977-07-25 | 1979-05-08 | Bausch & Lomb Incorporated | Polysiloxane composition and contact lens |
| US4189546A (en) | 1977-07-25 | 1980-02-19 | Bausch & Lomb Incorporated | Polysiloxane shaped article for use in biomedical applications |
| US4261875A (en) | 1979-01-31 | 1981-04-14 | American Optical Corporation | Contact lenses containing hydrophilic silicone polymers |
| US4254248A (en) | 1979-09-13 | 1981-03-03 | Bausch & Lomb Incorporated | Contact lens made from polymers of polysiloxane and polycyclic esters of acrylic acid or methacrylic acid |
| US4276402A (en) | 1979-09-13 | 1981-06-30 | Bausch & Lomb Incorporated | Polysiloxane/acrylic acid/polcyclic esters of methacrylic acid polymer contact lens |
| US4260725A (en) | 1979-12-10 | 1981-04-07 | Bausch & Lomb Incorporated | Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains |
| US4259467A (en) | 1979-12-10 | 1981-03-31 | Bausch & Lomb Incorporated | Hydrophilic contact lens made from polysiloxanes containing hydrophilic sidechains |
| US4355147A (en) | 1981-02-26 | 1982-10-19 | Bausch & Lomb Incorporated | Polysiloxane with polycyclic modifier composition and biomedical devices |
| US4327203A (en) | 1981-02-26 | 1982-04-27 | Bausch & Lomb Incorporated | Polysiloxane with cycloalkyl modifier composition and biomedical devices |
| US4341889A (en) | 1981-02-26 | 1982-07-27 | Bausch & Lomb Incorporated | Polysiloxane composition and biomedical devices |
| US4444711A (en) | 1981-12-21 | 1984-04-24 | Husky Injection Molding Systems Ltd. | Method of operating a two-shot injection-molding machine |
| US4661575A (en) | 1982-01-25 | 1987-04-28 | Hercules Incorporated | Dicyclopentadiene polymer product |
| US4460534A (en) | 1982-09-07 | 1984-07-17 | International Business Machines Corporation | Two-shot injection molding |
| US4486577A (en) | 1982-10-12 | 1984-12-04 | Ciba-Geigy Corporation | Strong, silicone containing polymers with high oxygen permeability |
| US4543398A (en) | 1983-04-28 | 1985-09-24 | Minnesota Mining And Manufacturing Company | Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols |
| US4695608A (en) | 1984-03-29 | 1987-09-22 | Minnesota Mining And Manufacturing Company | Continuous process for making polymers having pendant azlactone or macromolecular moieties |
| US4605712A (en) | 1984-09-24 | 1986-08-12 | Ciba-Geigy Corporation | Unsaturated polysiloxanes and polymers thereof |
| US4833218A (en) | 1984-12-18 | 1989-05-23 | Dow Corning Corporation | Hydrophilic silicone-organic copolymer elastomers containing bioactine agent |
| US4684538A (en) | 1986-02-21 | 1987-08-04 | Loctite Corporation | Polysiloxane urethane compounds and adhesive compositions, and method of making and using the same |
| DE3708308A1 (de) | 1986-04-10 | 1987-10-22 | Bayer Ag | Kontaktoptische gegenstaende |
| US4837289A (en) | 1987-04-30 | 1989-06-06 | Ciba-Geigy Corporation | UV- and heat curable terminal polyvinyl functional macromers and polymers thereof |
| US4910277A (en) * | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US5070170A (en) | 1988-02-26 | 1991-12-03 | Ciba-Geigy Corporation | Wettable, rigid gas permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof |
| US4954587A (en) | 1988-07-05 | 1990-09-04 | Ciba-Geigy Corporation | Dimethylacrylamide-copolymer hydrogels with high oxygen permeability |
| JPH0651795B2 (ja) | 1988-09-16 | 1994-07-06 | 信越化学工業株式会社 | メタクリル官能性ジメチルポリシロキサン |
| US4954586A (en) | 1989-01-17 | 1990-09-04 | Menicon Co., Ltd | Soft ocular lens material |
| US5262484A (en) | 1989-04-10 | 1993-11-16 | Minnesota Mining And Manufacturing Company | Azlactone graft copolymers |
| US5034461A (en) | 1989-06-07 | 1991-07-23 | Bausch & Lomb Incorporated | Novel prepolymers useful in biomedical devices |
| US5079319A (en) | 1989-10-25 | 1992-01-07 | Ciba-Geigy Corporation | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof |
| US5010141A (en) | 1989-10-25 | 1991-04-23 | Ciba-Geigy Corporation | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof |
| EP0603268B1 (en) | 1991-09-12 | 1996-12-18 | BAUSCH & LOMB INCORPORATED | Wettable silicone hydrogel compositions and methods |
| DE69211152T2 (de) | 1991-11-05 | 1997-01-02 | Bausch & Lomb | Zusammensetzungen von benetzbaren siliconhydrogels und verfahren zu deren herstellung |
| US5352714A (en) * | 1991-11-05 | 1994-10-04 | Bausch & Lomb Incorporated | Wettable silicone hydrogel compositions and methods for their manufacture |
| US5358995A (en) | 1992-05-15 | 1994-10-25 | Bausch & Lomb Incorporated | Surface wettable silicone hydrogels |
| US5292514A (en) | 1992-06-24 | 1994-03-08 | Minnesota Mining And Manufacturing Company | Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof |
| JP3195662B2 (ja) | 1992-08-24 | 2001-08-06 | 株式会社メニコン | 眼用レンズ材料 |
| JP2774233B2 (ja) | 1992-08-26 | 1998-07-09 | 株式会社メニコン | 眼用レンズ材料 |
| IL106922A (en) | 1992-09-14 | 1998-08-16 | Novartis Ag | Composite materials with one or more wettable surfaces and process for their preparation |
| US5750245A (en) | 1993-01-29 | 1998-05-12 | Minnesota Mining And Manufacturing Company | Thermally induced phase separated azlactone membrane |
| TW328535B (en) | 1993-07-02 | 1998-03-21 | Novartis Ag | Functional photoinitiators and their manufacture |
| US6800225B1 (en) | 1994-07-14 | 2004-10-05 | Novartis Ag | Process and device for the manufacture of mouldings and mouldings manufactured in accordance with that process |
| TW272976B (https=) | 1993-08-06 | 1996-03-21 | Ciba Geigy Ag | |
| US5408002A (en) | 1993-09-09 | 1995-04-18 | Minnesota Mining And Manufacturing Company | Azlactone-functional polymer blends, articles produced therefrom and methods for preparing both |
| US5894002A (en) | 1993-12-13 | 1999-04-13 | Ciba Vision Corporation | Process and apparatus for the manufacture of a contact lens |
| US5476665A (en) | 1994-04-13 | 1995-12-19 | Minnesota Mining And Manufacturing Company | Azlactone functional particles incorporated in a membrane formed by solvent phase inversion |
| US5843346A (en) | 1994-06-30 | 1998-12-01 | Polymer Technology Corporation | Method of cast molding contact lenses |
| US5760100B1 (en) | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
| TW353086B (en) | 1994-12-30 | 1999-02-21 | Novartis Ag | Method for multistep coating of a surface |
| TW425410B (en) * | 1995-02-03 | 2001-03-11 | Novartis Ag | Preparation of the crosslinked tinted polymers and their moldings |
| AU4438696A (en) * | 1995-02-03 | 1996-08-21 | Novartis Ag | Crosslinked polymers |
| TW349967B (en) | 1995-02-03 | 1999-01-11 | Novartis Ag | Process for producing contact lenses and a cross-linkable polyvinylalcohol used therefor |
| US5731087A (en) * | 1995-06-07 | 1998-03-24 | Union Carbide Chemicals & Plastics Technology Corporation | Lubricious coatings containing polymers with vinyl and carboxylic acid moieties |
| AR009439A1 (es) | 1996-12-23 | 2000-04-12 | Novartis Ag | Un articulo que comprende un sustrato con un recubrimiento polimerico primario que porta grupos reactivos predominantemente en su superficie, unmetodo para preparar dicho articulo, un articulo que posee un recubrimiento de tipo hibrido y una lente de contacto |
| US6221467B1 (en) * | 1997-06-03 | 2001-04-24 | Scimed Life Systems, Inc. | Coating gradient for lubricious coatings on balloon catheters |
| US6265509B1 (en) * | 1997-07-30 | 2001-07-24 | Novartis Ag | Crosslinked polymers |
| AU9627298A (en) | 1997-09-23 | 1999-04-12 | Novartis Ag | Method for hydrogel surface treatment and article formed therefrom |
| TW429327B (en) | 1997-10-21 | 2001-04-11 | Novartis Ag | Single mould alignment |
| US6451871B1 (en) | 1998-11-25 | 2002-09-17 | Novartis Ag | Methods of modifying surface characteristics |
| US6822016B2 (en) | 2001-09-10 | 2004-11-23 | Johnson & Johnson Vision Care, Inc. | Biomedical devices containing internal wetting agents |
| US5962548A (en) | 1998-03-02 | 1999-10-05 | Johnson & Johnson Vision Products, Inc. | Silicone hydrogel polymers |
| US7052131B2 (en) | 2001-09-10 | 2006-05-30 | J&J Vision Care, Inc. | Biomedical devices containing internal wetting agents |
| US6367929B1 (en) | 1998-03-02 | 2002-04-09 | Johnson & Johnson Vision Care, Inc. | Hydrogel with internal wetting agent |
| TW473488B (en) | 1998-04-30 | 2002-01-21 | Novartis Ag | Composite materials, biomedical articles formed thereof and process for their manufacture |
| US6039913A (en) | 1998-08-27 | 2000-03-21 | Novartis Ag | Process for the manufacture of an ophthalmic molding |
| US6207796B1 (en) * | 1998-11-18 | 2001-03-27 | Nippon Shokubai Co., Ltd. | Production process for hydrophilic polymer |
| US5981675A (en) | 1998-12-07 | 1999-11-09 | Bausch & Lomb Incorporated | Silicone-containing macromonomers and low water materials |
| US6440571B1 (en) * | 1999-05-20 | 2002-08-27 | Bausch & Lomb Incorporated | Surface treatment of silicone medical devices with reactive hydrophilic polymers |
| US6630243B2 (en) | 1999-05-20 | 2003-10-07 | Bausch & Lomb Incorporated | Surface treatment of silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating |
| HK1048331B (en) | 1999-07-27 | 2004-08-13 | Bausch & Lomb Incorporated | Contact lens material |
| JP2001163933A (ja) | 1999-10-27 | 2001-06-19 | Novartis Ag | 材料表面を改質する方法 |
| JP2001163932A (ja) | 1999-10-27 | 2001-06-19 | Novartis Ag | 材料表面を改質する方法 |
| AR026245A1 (es) | 1999-10-27 | 2003-02-05 | Novartis Ag | Proceso de recubrimiento |
| JP2001158813A (ja) | 1999-10-27 | 2001-06-12 | Novartis Ag | 材料表面を被覆する方法 |
| US6719929B2 (en) | 2000-02-04 | 2004-04-13 | Novartis Ag | Method for modifying a surface |
| AR027348A1 (es) | 2000-02-04 | 2003-03-26 | Novartis Ag | Proceso para recubrir una superficie |
| US7521519B1 (en) | 2000-03-14 | 2009-04-21 | Novartis Ag | Organic compounds |
| CA2682118A1 (en) | 2000-03-24 | 2001-09-27 | Novartis Ag | Crosslinkable or polymerizable prepolymers |
| US6599559B1 (en) | 2000-04-03 | 2003-07-29 | Bausch & Lomb Incorporated | Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers |
| US6852353B2 (en) * | 2000-08-24 | 2005-02-08 | Novartis Ag | Process for surface modifying substrates and modified substrates resulting therefrom |
| JP4043789B2 (ja) | 2001-01-24 | 2008-02-06 | ノバルティス アクチエンゲゼルシャフト | 表面を修飾するための方法 |
| US6835410B2 (en) | 2001-05-21 | 2004-12-28 | Novartis Ag | Bottle-brush type coatings with entangled hydrophilic polymer |
| JP2003066381A (ja) | 2001-05-23 | 2003-03-05 | Novartis Ag | 流体で物品を処理するためのシステム及び方法 |
| TW200407367A (en) | 2001-11-13 | 2004-05-16 | Novartis Ag | Method for modifying the surface of biomedical articles |
| AR038269A1 (es) | 2002-01-09 | 2005-01-12 | Novartis Ag | Articulos polimericos que tienen un recubrimiento lubrico, y metodo para fabricarlos |
| GB0201165D0 (en) | 2002-01-18 | 2002-03-06 | Unilever Plc | Azetidinium modidfied poymers and fabric treatment composition |
| US6926965B2 (en) | 2002-09-11 | 2005-08-09 | Novartis Ag | LbL-coated medical device and method for making the same |
| US6896926B2 (en) | 2002-09-11 | 2005-05-24 | Novartis Ag | Method for applying an LbL coating onto a medical device |
| US7384590B2 (en) | 2002-12-17 | 2008-06-10 | Novartis Ag | System and method for curing polymeric moldings |
| US7387759B2 (en) | 2002-12-17 | 2008-06-17 | Novartis Ag | System and method for curing polymeric moldings having a masking collar |
| US7249848B2 (en) | 2004-09-30 | 2007-07-31 | Johnson & Johnson Vision Care, Inc. | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents |
| US20060065138A1 (en) * | 2004-09-30 | 2006-03-30 | Tucker Robert C | Pad printing method for making colored contact lenses |
| US7556858B2 (en) | 2004-09-30 | 2009-07-07 | 3M Innovative Properties Company | Substrate with attached dendrimers |
| US8044112B2 (en) | 2006-03-30 | 2011-10-25 | Novartis Ag | Method for applying a coating onto a silicone hydrogel lens |
| US7858000B2 (en) | 2006-06-08 | 2010-12-28 | Novartis Ag | Method of making silicone hydrogel contact lenses |
| PT2038310E (pt) | 2006-07-12 | 2010-08-25 | Novartis Ag | Copolímeros reticuláveis por via actínica para o fabrico de lentes de contacto |
| US9052442B2 (en) * | 2006-10-30 | 2015-06-09 | Novartis Ag | Method for applying a coating onto a silicone hydrogel lens |
| JP5669396B2 (ja) | 2006-12-13 | 2015-02-12 | ノバルティス アーゲー | 化学線硬化性シリコーンヒドロゲルコポリマーおよびその使用 |
| AR064286A1 (es) | 2006-12-13 | 2009-03-25 | Quiceno Gomez Alexandra Lorena | Produccion de dispositivos oftalmicos basados en la polimerizacion por crecimiento escalonado fotoinducida |
| CN101568354B (zh) | 2006-12-21 | 2013-05-22 | 诺瓦提斯公司 | 涂覆生物医学器件的方法 |
| CA2676294C (en) * | 2007-02-09 | 2014-10-21 | Novartis Ag | Cross-linkable polyionic coatings for contact lenses |
| KR101482808B1 (ko) | 2007-03-22 | 2015-01-14 | 노파르티스 아게 | 현수 폴리실록산-함유 중합체 사슬이 있는 예비중합체 |
| US8071703B2 (en) | 2007-03-22 | 2011-12-06 | Novartis Ag | Silicone-containing prepolymers with dangling hydrophilic polymer chains |
| US20090111942A1 (en) | 2007-10-25 | 2009-04-30 | Bausch & Lomb Incorporated | Method for Making Surface Modified Biomedical Devices |
| EP2432821B1 (en) | 2009-05-22 | 2017-08-30 | Novartis AG | Actinically-crosslinkable siloxane-containing copolymers |
| CA2760747C (en) | 2009-05-22 | 2016-12-13 | Novartis Ag | Actinically-crosslinkable siloxane-containing copolymers |
| US9623614B2 (en) * | 2010-11-10 | 2017-04-18 | Novartis Ag | Method for making contact lenses |
-
2010
- 2010-11-15 TW TW099139240A patent/TWI483996B/zh active
- 2010-12-06 CA CA2777961A patent/CA2777961C/en active Active
- 2010-12-06 WO PCT/US2010/059022 patent/WO2011071791A1/en not_active Ceased
- 2010-12-06 JP JP2012543176A patent/JP5877793B2/ja active Active
- 2010-12-06 EP EP10836462.1A patent/EP2510052B1/en active Active
- 2010-12-06 US US12/960,617 patent/US8557334B2/en active Active
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