JP2013512694A - 養子細胞療法のための細胞を培養する方法 - Google Patents
養子細胞療法のための細胞を培養する方法 Download PDFInfo
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- JP2013512694A JP2013512694A JP2012543271A JP2012543271A JP2013512694A JP 2013512694 A JP2013512694 A JP 2013512694A JP 2012543271 A JP2012543271 A JP 2012543271A JP 2012543271 A JP2012543271 A JP 2012543271A JP 2013512694 A JP2013512694 A JP 2013512694A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26776109P | 2009-12-08 | 2009-12-08 | |
| US61/267,761 | 2009-12-08 | ||
| PCT/US2010/059591 WO2011072088A2 (en) | 2009-12-08 | 2010-12-08 | Improved methods of cell culture for adoptive cell therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015095864A Division JP2015133997A (ja) | 2009-12-08 | 2015-05-08 | 養子細胞療法のための細胞を培養する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013512694A true JP2013512694A (ja) | 2013-04-18 |
| JP2013512694A5 JP2013512694A5 (enExample) | 2014-01-30 |
Family
ID=44082417
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543271A Pending JP2013512694A (ja) | 2009-12-08 | 2010-12-08 | 養子細胞療法のための細胞を培養する方法 |
| JP2015095864A Pending JP2015133997A (ja) | 2009-12-08 | 2015-05-08 | 養子細胞療法のための細胞を培養する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015095864A Pending JP2015133997A (ja) | 2009-12-08 | 2015-05-08 | 養子細胞療法のための細胞を培養する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8809050B2 (enExample) |
| EP (2) | EP2510086A4 (enExample) |
| JP (2) | JP2013512694A (enExample) |
| CN (1) | CN102762719A (enExample) |
| CA (1) | CA2783550A1 (enExample) |
| IL (1) | IL220232A0 (enExample) |
| SG (1) | SG181559A1 (enExample) |
| WO (1) | WO2011072088A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015133997A (ja) * | 2009-12-08 | 2015-07-27 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 養子細胞療法のための細胞を培養する方法 |
| JP2016530895A (ja) * | 2013-09-23 | 2016-10-06 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 動物細胞を遺伝子改変する改良された方法 |
| US9567565B2 (en) | 2009-12-08 | 2017-02-14 | Juan F. Vera | Methods of cell culture for adoptive cell therapy |
| CN110199016A (zh) * | 2016-11-17 | 2019-09-03 | 艾欧凡斯生物治疗公司 | 残余肿瘤浸润淋巴细胞及其制备和使用方法 |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP3101122B1 (en) | 2009-08-24 | 2023-06-14 | Baylor College of Medicine | Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses |
| US20120244133A1 (en) | 2011-03-22 | 2012-09-27 | The United States of America, as represented by the Secretary, Department of Health and | Methods of growing tumor infiltrating lymphocytes in gas-permeable containers |
| SG11201404677TA (en) | 2011-12-12 | 2014-11-27 | Cell Medica Ltd | Process of expanding t cells |
| GB201121308D0 (en) | 2011-12-12 | 2012-01-25 | Cell Medica Ltd | Process |
| EP4089167A1 (en) | 2012-02-09 | 2022-11-16 | Baylor College of Medicine | Pepmixes to generate multiviral ctls with broad specificity |
| SG10202111564SA (en) * | 2012-05-18 | 2021-12-30 | Wilson Wolf Mfg Corporation | Improved methods of cell culture for adoptive cell therapy |
| EP2859093A4 (en) * | 2012-06-11 | 2016-08-17 | Wolf Wilson Mfg Corp | IMPROVED METHODS FOR CELL CULTURES FOR ADOPTIVE CELL THERAPIES |
| US20150320799A1 (en) | 2012-12-20 | 2015-11-12 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| AU2014302589B2 (en) | 2013-06-24 | 2020-05-14 | Wilson Wolf Manufacturing, LLC | Closed system device and methods for gas permeable cell culture process |
| US20170044496A1 (en) | 2014-04-10 | 2017-02-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy |
| EP3350600A4 (en) | 2015-09-18 | 2019-04-17 | Baylor College of Medicine | DISTINCTION OF AN IMMUNOGENIC ANTIGEN OF A PATHOGEN AND CORRELATION WITH CLINICAL EFFECTIVENESS |
| GB201522097D0 (en) | 2015-12-15 | 2016-01-27 | Cellular Therapeutics Ltd | Cells |
| CN105418766A (zh) * | 2015-12-22 | 2016-03-23 | 深圳市北科生物科技有限公司 | 一种用于免疫治疗的eb病毒lmp2a串联表位肽及其应用 |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Car t細胞療法のための方法および組成物 |
| US10052372B2 (en) * | 2016-05-24 | 2018-08-21 | Tessa Therapeutics Pte Ltd | T cell expansion |
| SG11201900138TA (en) | 2016-07-07 | 2019-02-27 | Iovance Biotherapeutics Inc | Programmed death 1 ligand 1 (pd-l1) binding proteins and methods of use thereof |
| AU2017347851B2 (en) | 2016-10-26 | 2024-03-07 | Iovance Biotherapeutics, Inc. | Restimulation of cryopreserved tumor infiltrating lymphocytes |
| TWI788307B (zh) | 2016-10-31 | 2023-01-01 | 美商艾歐凡斯生物治療公司 | 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞 |
| CN110462027A (zh) | 2017-01-06 | 2019-11-15 | 艾欧凡斯生物治疗公司 | 用肿瘤坏死因子受体超家族(tnfrsf)激动剂扩增肿瘤浸润淋巴细胞(til)及til和tnfrsf激动剂的治疗组合 |
| CA3049165A1 (en) | 2017-01-06 | 2018-07-12 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof |
| GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
| EP3579870A4 (en) | 2017-02-07 | 2020-12-30 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | PHOSPHOLIPID ETHER (PLE) T CAR-LYMPHOCYTE TUMOR (CTCT) TARGETING AGENTS |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| JOP20190224A1 (ar) | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
| US11254913B1 (en) | 2017-03-29 | 2022-02-22 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| WO2018195014A1 (en) | 2017-04-19 | 2018-10-25 | Neubiser Richard | Bioreactor for biological material |
| IL270412B2 (en) | 2017-05-10 | 2025-03-01 | Iovance Biotherapeutics Inc | Expansion of infiltrating lymphocytes from liquid samples and their medical uses |
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| KR20200100060A (ko) | 2017-11-17 | 2020-08-25 | 이오반스 바이오테라퓨틱스, 인크. | 미세 바늘 흡인물 및 소형 생검물로부터의 til 확장 |
| EP3714041A1 (en) | 2017-11-22 | 2020-09-30 | Iovance Biotherapeutics, Inc. | Expansion of peripheral blood lymphocytes (pbls) from peripheral blood |
| WO2019118873A2 (en) | 2017-12-15 | 2019-06-20 | Iovance Biotherapeutics, Inc. | Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof |
| JP2021509586A (ja) | 2018-01-08 | 2021-04-01 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍抗原特異的t細胞について濃縮されたtil製品を生成するためのプロセス |
| US11713446B2 (en) | 2018-01-08 | 2023-08-01 | Iovance Biotherapeutics, Inc. | Processes for generating TIL products enriched for tumor antigen-specific T-cells |
| WO2019136459A1 (en) | 2018-01-08 | 2019-07-11 | Iovance Biotherapeutics, Inc. | Processes for generating til products enriched for tumor antigen-specific t-cells |
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| WO2019165237A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
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| JPH11187868A (ja) * | 1997-12-26 | 1999-07-13 | Teijin Ltd | ウィルスまたは細胞の培養法 |
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2010
- 2010-12-08 JP JP2012543271A patent/JP2013512694A/ja active Pending
- 2010-12-08 US US12/963,597 patent/US8809050B2/en active Active
- 2010-12-08 EP EP10836660.0A patent/EP2510086A4/en not_active Withdrawn
- 2010-12-08 CN CN2010800637927A patent/CN102762719A/zh active Pending
- 2010-12-08 EP EP13192463.1A patent/EP2698430A3/en not_active Withdrawn
- 2010-12-08 CA CA2783550A patent/CA2783550A1/en not_active Abandoned
- 2010-12-08 WO PCT/US2010/059591 patent/WO2011072088A2/en not_active Ceased
- 2010-12-08 SG SG2012041893A patent/SG181559A1/en unknown
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2012
- 2012-06-07 IL IL220232A patent/IL220232A0/en unknown
-
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| US9567565B2 (en) | 2009-12-08 | 2017-02-14 | Juan F. Vera | Methods of cell culture for adoptive cell therapy |
| US12454667B2 (en) | 2009-12-08 | 2025-10-28 | Wilson Wolf Manufacturing, LLC | Methods of cell culture for adoptive cell therapy |
| JP2015133997A (ja) * | 2009-12-08 | 2015-07-27 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 養子細胞療法のための細胞を培養する方法 |
| US10533156B2 (en) | 2009-12-08 | 2020-01-14 | Baylor College Of Medicine | Methods of cell culture for adoptive cell therapy |
| US11999969B2 (en) | 2009-12-08 | 2024-06-04 | Wilson Wolf Manufacturing | Methods of cell culture for adoptive cell therapy |
| JP2016530895A (ja) * | 2013-09-23 | 2016-10-06 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 動物細胞を遺伝子改変する改良された方法 |
| JP2019534030A (ja) * | 2016-11-17 | 2019-11-28 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| US11293009B2 (en) | 2016-11-17 | 2022-04-05 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| US11401507B2 (en) | 2016-11-17 | 2022-08-02 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| JP7125392B2 (ja) | 2016-11-17 | 2022-08-24 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| JP2022167931A (ja) * | 2016-11-17 | 2022-11-04 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| US11220670B2 (en) | 2016-11-17 | 2022-01-11 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| US12233075B2 (en) | 2016-11-17 | 2025-02-25 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| JP7675688B2 (ja) | 2016-11-17 | 2025-05-13 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| CN110199016A (zh) * | 2016-11-17 | 2019-09-03 | 艾欧凡斯生物治疗公司 | 残余肿瘤浸润淋巴细胞及其制备和使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2783550A1 (en) | 2011-06-16 |
| EP2510086A4 (en) | 2013-05-22 |
| EP2698430A2 (en) | 2014-02-19 |
| WO2011072088A2 (en) | 2011-06-16 |
| US8809050B2 (en) | 2014-08-19 |
| IL220232A0 (en) | 2012-07-31 |
| EP2510086A2 (en) | 2012-10-17 |
| US20110136228A1 (en) | 2011-06-09 |
| JP2015133997A (ja) | 2015-07-27 |
| CN102762719A (zh) | 2012-10-31 |
| SG181559A1 (en) | 2012-07-30 |
| WO2011072088A3 (en) | 2011-10-13 |
| EP2698430A3 (en) | 2014-03-05 |
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