JP2013512694A - 養子細胞療法のための細胞を培養する方法 - Google Patents
養子細胞療法のための細胞を培養する方法 Download PDFInfo
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- JP2013512694A JP2013512694A JP2012543271A JP2012543271A JP2013512694A JP 2013512694 A JP2013512694 A JP 2013512694A JP 2012543271 A JP2012543271 A JP 2012543271A JP 2012543271 A JP2012543271 A JP 2012543271A JP 2013512694 A JP2013512694 A JP 2013512694A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26776109P | 2009-12-08 | 2009-12-08 | |
| US61/267,761 | 2009-12-08 | ||
| PCT/US2010/059591 WO2011072088A2 (en) | 2009-12-08 | 2010-12-08 | Improved methods of cell culture for adoptive cell therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015095864A Division JP2015133997A (ja) | 2009-12-08 | 2015-05-08 | 養子細胞療法のための細胞を培養する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013512694A true JP2013512694A (ja) | 2013-04-18 |
| JP2013512694A5 JP2013512694A5 (enExample) | 2014-01-30 |
Family
ID=44082417
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543271A Pending JP2013512694A (ja) | 2009-12-08 | 2010-12-08 | 養子細胞療法のための細胞を培養する方法 |
| JP2015095864A Pending JP2015133997A (ja) | 2009-12-08 | 2015-05-08 | 養子細胞療法のための細胞を培養する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015095864A Pending JP2015133997A (ja) | 2009-12-08 | 2015-05-08 | 養子細胞療法のための細胞を培養する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8809050B2 (enExample) |
| EP (2) | EP2510086A4 (enExample) |
| JP (2) | JP2013512694A (enExample) |
| CN (1) | CN102762719A (enExample) |
| CA (1) | CA2783550A1 (enExample) |
| IL (1) | IL220232A0 (enExample) |
| SG (1) | SG181559A1 (enExample) |
| WO (1) | WO2011072088A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015133997A (ja) * | 2009-12-08 | 2015-07-27 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 養子細胞療法のための細胞を培養する方法 |
| JP2016530895A (ja) * | 2013-09-23 | 2016-10-06 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 動物細胞を遺伝子改変する改良された方法 |
| US9567565B2 (en) | 2009-12-08 | 2017-02-14 | Juan F. Vera | Methods of cell culture for adoptive cell therapy |
| CN110199016A (zh) * | 2016-11-17 | 2019-09-03 | 艾欧凡斯生物治疗公司 | 残余肿瘤浸润淋巴细胞及其制备和使用方法 |
Families Citing this family (72)
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| CA2772076A1 (en) | 2009-08-24 | 2011-03-10 | Baylor College Of Medicine | Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses |
| US20120244133A1 (en) | 2011-03-22 | 2012-09-27 | The United States of America, as represented by the Secretary, Department of Health and | Methods of growing tumor infiltrating lymphocytes in gas-permeable containers |
| GB201121308D0 (en) | 2011-12-12 | 2012-01-25 | Cell Medica Ltd | Process |
| BR112014014591A8 (pt) | 2011-12-12 | 2017-07-04 | Baylor College Medicine | processo para a expansão in vitro de células t específicas de antígeno, produto de células t autólogas ou alogênicas expandidas, composição farmacêutica, e, método de tratamento de um paciente, e, usos de uma linhagem de células engenheirada, de células dendríticas pulsadas com misturas de antígeno-peptídeo, de t-apcs pulsadas com misturas de antígeno-peptídeo/peptídeo, e de misturas de antígeno-peptídeo com pbmcs |
| EP2812431B1 (en) | 2012-02-09 | 2019-07-17 | Baylor College Of Medicine | Pepmixes to generate multiviral ctls with broad specificity |
| CN104379727A (zh) * | 2012-05-18 | 2015-02-25 | 威尔逊沃夫制造公司 | 改进的用于过继细胞治疗的细胞培养方法 |
| CN110241086A (zh) * | 2012-06-11 | 2019-09-17 | 威尔逊沃夫制造公司 | 用于过继细胞疗法的改进的细胞培养方法 |
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| SG10201705494YA (en) | 2013-06-24 | 2017-08-30 | Wolf Wilson Mfg Corp | Closed system device and methods for gas permeable cell culture process |
| ES2980788T3 (es) | 2014-04-10 | 2024-10-03 | H Lee Moffitt Cancer Ct & Res | Expansión mejorada de linfocitos infiltrantes de tumores para terapia celular adoptiva |
| US11167024B2 (en) | 2015-09-18 | 2021-11-09 | Baylor College Of Medicine | Immunogenic antigen identification from a pathogen and correlation to clinical efficacy |
| GB201522097D0 (en) | 2015-12-15 | 2016-01-27 | Cellular Therapeutics Ltd | Cells |
| CN105418766A (zh) * | 2015-12-22 | 2016-03-23 | 深圳市北科生物科技有限公司 | 一种用于免疫治疗的eb病毒lmp2a串联表位肽及其应用 |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| US10052372B2 (en) * | 2016-05-24 | 2018-08-21 | Tessa Therapeutics Pte Ltd | T cell expansion |
| US11141434B2 (en) | 2016-07-07 | 2021-10-12 | Iovance Biotherapeutics, Inc. | Programmed death 1 ligand 1 (PD-L1) binding proteins and methods of use thereof |
| CN110099998A (zh) | 2016-10-26 | 2019-08-06 | 艾欧凡斯生物治疗公司 | 冷冻保存的肿瘤浸润淋巴细胞的再刺激 |
| TWI788307B (zh) | 2016-10-31 | 2023-01-01 | 美商艾歐凡斯生物治療公司 | 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞 |
| ES3055314T3 (en) | 2017-01-06 | 2026-02-11 | Iovance Biotherapeutics Inc | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof |
| AU2018205234B2 (en) | 2017-01-06 | 2024-09-19 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes (TILs) with tumor necrosis factor receptor superfamily (TNFRSF) agonists and therapeutic combinations of TILs and TNFRSF agonists |
| GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| US11254913B1 (en) | 2017-03-29 | 2022-02-22 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| JOP20190224A1 (ar) | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
| WO2018195014A1 (en) | 2017-04-19 | 2018-10-25 | Neubiser Richard | Bioreactor for biological material |
| WO2018209115A1 (en) | 2017-05-10 | 2018-11-15 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof |
| KR102920712B1 (ko) | 2017-05-24 | 2026-01-30 | 노파르티스 아게 | 항체-사이토카인 생착된 단백질 및 암 치료에 있어서의 사용 방법 |
| TW201919662A (zh) | 2017-06-05 | 2019-06-01 | 美商艾歐凡斯生物治療公司 | 對雙重難治性黑色素瘤使用腫瘤浸潤性淋巴細胞之方法 |
| JP7557367B2 (ja) | 2017-11-17 | 2024-09-27 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 細針吸引及び小生検からのtil拡大培養 |
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| US11713446B2 (en) | 2018-01-08 | 2023-08-01 | Iovance Biotherapeutics, Inc. | Processes for generating TIL products enriched for tumor antigen-specific T-cells |
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| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| AU2019218729B2 (en) | 2018-02-06 | 2025-12-04 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific CARs exhibiting optimal T cell function against FL-PLE labelled tumors |
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- 2010-12-08 CA CA2783550A patent/CA2783550A1/en not_active Abandoned
- 2010-12-08 JP JP2012543271A patent/JP2013512694A/ja active Pending
- 2010-12-08 SG SG2012041893A patent/SG181559A1/en unknown
- 2010-12-08 US US12/963,597 patent/US8809050B2/en active Active
- 2010-12-08 EP EP10836660.0A patent/EP2510086A4/en not_active Withdrawn
- 2010-12-08 EP EP13192463.1A patent/EP2698430A3/en not_active Withdrawn
- 2010-12-08 CN CN2010800637927A patent/CN102762719A/zh active Pending
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2015
- 2015-05-08 JP JP2015095864A patent/JP2015133997A/ja active Pending
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| US9567565B2 (en) | 2009-12-08 | 2017-02-14 | Juan F. Vera | Methods of cell culture for adoptive cell therapy |
| US12454667B2 (en) | 2009-12-08 | 2025-10-28 | Wilson Wolf Manufacturing, LLC | Methods of cell culture for adoptive cell therapy |
| JP2015133997A (ja) * | 2009-12-08 | 2015-07-27 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 養子細胞療法のための細胞を培養する方法 |
| US10533156B2 (en) | 2009-12-08 | 2020-01-14 | Baylor College Of Medicine | Methods of cell culture for adoptive cell therapy |
| US11999969B2 (en) | 2009-12-08 | 2024-06-04 | Wilson Wolf Manufacturing | Methods of cell culture for adoptive cell therapy |
| JP2016530895A (ja) * | 2013-09-23 | 2016-10-06 | ウィルソン ウォルフ マニュファクチャリング コーポレイションWilson Wolf Manufacturing Corporation | 動物細胞を遺伝子改変する改良された方法 |
| JP2019534030A (ja) * | 2016-11-17 | 2019-11-28 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| US11293009B2 (en) | 2016-11-17 | 2022-04-05 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| US11401507B2 (en) | 2016-11-17 | 2022-08-02 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| JP7125392B2 (ja) | 2016-11-17 | 2022-08-24 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| JP2022167931A (ja) * | 2016-11-17 | 2022-11-04 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| US11220670B2 (en) | 2016-11-17 | 2022-01-11 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| US12233075B2 (en) | 2016-11-17 | 2025-02-25 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| JP7675688B2 (ja) | 2016-11-17 | 2025-05-13 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
| CN110199016A (zh) * | 2016-11-17 | 2019-09-03 | 艾欧凡斯生物治疗公司 | 残余肿瘤浸润淋巴细胞及其制备和使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20110136228A1 (en) | 2011-06-09 |
| EP2510086A2 (en) | 2012-10-17 |
| EP2510086A4 (en) | 2013-05-22 |
| CA2783550A1 (en) | 2011-06-16 |
| JP2015133997A (ja) | 2015-07-27 |
| SG181559A1 (en) | 2012-07-30 |
| WO2011072088A2 (en) | 2011-06-16 |
| EP2698430A2 (en) | 2014-02-19 |
| CN102762719A (zh) | 2012-10-31 |
| IL220232A0 (en) | 2012-07-31 |
| EP2698430A3 (en) | 2014-03-05 |
| WO2011072088A3 (en) | 2011-10-13 |
| US8809050B2 (en) | 2014-08-19 |
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