SG181559A1 - Improved methods of cell culture for adoptive cell therapy - Google Patents

Improved methods of cell culture for adoptive cell therapy Download PDF

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Publication number
SG181559A1
SG181559A1 SG2012041893A SG2012041893A SG181559A1 SG 181559 A1 SG181559 A1 SG 181559A1 SG 2012041893 A SG2012041893 A SG 2012041893A SG 2012041893 A SG2012041893 A SG 2012041893A SG 181559 A1 SG181559 A1 SG 181559A1
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SG
Singapore
Prior art keywords
cells
cell
surface density
growth
culture
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SG2012041893A
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English (en)
Inventor
Juan F Vera
Clio M Rooney
Ann M Leen
John R Wilson
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Wolf Wilson Mfg Corp
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Application filed by Wolf Wilson Mfg Corp filed Critical Wolf Wilson Mfg Corp
Publication of SG181559A1 publication Critical patent/SG181559A1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG2012041893A 2009-12-08 2010-12-08 Improved methods of cell culture for adoptive cell therapy SG181559A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26776109P 2009-12-08 2009-12-08
PCT/US2010/059591 WO2011072088A2 (en) 2009-12-08 2010-12-08 Improved methods of cell culture for adoptive cell therapy

Publications (1)

Publication Number Publication Date
SG181559A1 true SG181559A1 (en) 2012-07-30

Family

ID=44082417

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012041893A SG181559A1 (en) 2009-12-08 2010-12-08 Improved methods of cell culture for adoptive cell therapy

Country Status (8)

Country Link
US (1) US8809050B2 (enExample)
EP (2) EP2510086A4 (enExample)
JP (2) JP2013512694A (enExample)
CN (1) CN102762719A (enExample)
CA (1) CA2783550A1 (enExample)
IL (1) IL220232A0 (enExample)
SG (1) SG181559A1 (enExample)
WO (1) WO2011072088A2 (enExample)

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Also Published As

Publication number Publication date
CA2783550A1 (en) 2011-06-16
EP2510086A4 (en) 2013-05-22
JP2013512694A (ja) 2013-04-18
EP2698430A2 (en) 2014-02-19
WO2011072088A2 (en) 2011-06-16
US8809050B2 (en) 2014-08-19
IL220232A0 (en) 2012-07-31
EP2510086A2 (en) 2012-10-17
US20110136228A1 (en) 2011-06-09
JP2015133997A (ja) 2015-07-27
CN102762719A (zh) 2012-10-31
WO2011072088A3 (en) 2011-10-13
EP2698430A3 (en) 2014-03-05

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