JP2013511958A5 - - Google Patents
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- Publication number
- JP2013511958A5 JP2013511958A5 JP2012524961A JP2012524961A JP2013511958A5 JP 2013511958 A5 JP2013511958 A5 JP 2013511958A5 JP 2012524961 A JP2012524961 A JP 2012524961A JP 2012524961 A JP2012524961 A JP 2012524961A JP 2013511958 A5 JP2013511958 A5 JP 2013511958A5
- Authority
- JP
- Japan
- Prior art keywords
- oligopeptide
- antigen
- hla
- ctl
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000015636 Oligopeptides Human genes 0.000 claims description 24
- 108010038807 Oligopeptides Proteins 0.000 claims description 24
- 210000000612 antigen-presenting cell Anatomy 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 9
- 102000040430 polynucleotide Human genes 0.000 claims description 7
- 108091033319 polynucleotide Proteins 0.000 claims description 7
- 239000002157 polynucleotide Substances 0.000 claims description 7
- 230000001939 inductive effect Effects 0.000 claims description 5
- 229960005486 vaccine Drugs 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 3
- 210000001744 T-lymphocyte Anatomy 0.000 claims description 3
- 230000028993 immune response Effects 0.000 claims description 3
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 13
- 239000000427 antigen Substances 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 102000025850 HLA-A2 Antigen Human genes 0.000 claims 6
- 108010074032 HLA-A2 Antigen Proteins 0.000 claims 6
- 150000001413 amino acids Chemical class 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 108091008874 T cell receptors Proteins 0.000 claims 2
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- 210000001808 exosome Anatomy 0.000 claims 1
- 125000001909 leucine group Chemical group [H]N(*)C(C(*)=O)C([H])([H])C(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 230000002980 postoperative effect Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 239000012634 fragment Substances 0.000 description 2
- 208000000461 Esophageal Neoplasms Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 201000004101 esophageal cancer Diseases 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26565709P | 2009-12-01 | 2009-12-01 | |
| US61/265,657 | 2009-12-01 | ||
| US37143410P | 2010-08-06 | 2010-08-06 | |
| US61/371,434 | 2010-08-06 | ||
| PCT/JP2010/006966 WO2011067920A1 (en) | 2009-12-01 | 2010-11-30 | Imp-3 oligopeptides and vaccines including the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013511958A JP2013511958A (ja) | 2013-04-11 |
| JP2013511958A5 true JP2013511958A5 (https=) | 2014-01-23 |
Family
ID=44114782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012524961A Pending JP2013511958A (ja) | 2009-12-01 | 2010-11-30 | Ｉｍｐ−３オリゴペプチドおよびそれを含むワクチン |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20120308590A1 (https=) |
| EP (1) | EP2507256A4 (https=) |
| JP (1) | JP2013511958A (https=) |
| KR (1) | KR20120099106A (https=) |
| CN (1) | CN102741271B (https=) |
| AU (1) | AU2010327878B2 (https=) |
| BR (1) | BR112012013139A2 (https=) |
| CA (1) | CA2782271A1 (https=) |
| IL (1) | IL219976A0 (https=) |
| MX (1) | MX2012006126A (https=) |
| RU (1) | RU2550695C2 (https=) |
| SG (2) | SG181107A1 (https=) |
| TW (1) | TW201124530A (https=) |
| WO (1) | WO2011067920A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150359864A1 (en) | 2012-03-09 | 2015-12-17 | Oncotherapy Science, Inc. | Pharmaceutical composition containing peptides |
| TWI643867B (zh) | 2013-05-24 | 2018-12-11 | 日商腫瘤療法 科學股份有限公司 | 對於ｔｈ１細胞之ｉｍｐ－３抗原決定位胜肽及含此之疫苗 |
| EP3981416B1 (en) | 2014-08-04 | 2024-03-20 | OncoTherapy Science, Inc. | Koc1-derived peptide and vaccine including same |
| GB201603568D0 (en) * | 2016-03-01 | 2016-04-13 | Immatics Biotechnologies Gmbh | Efficient treatment options including peptides and combination of peptide and cell based medicaments for use in immunotherapy against urinary bladder cancer |
| NZ746387A (en) * | 2016-03-16 | 2022-08-26 | Immatics Biotechnologies Gmbh | Transfected t-cells and t-cell receptors for use in immunotherapy against cancers |
| GB201604494D0 (en) * | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Transfected T-Cells and T-Cell receptors for use in immunotherapy against cancers |
| GB201604490D0 (en) * | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Peptides combination of peptides for use in immunotherapy against cancers |
| PL4029494T3 (pl) | 2017-01-25 | 2026-03-23 | Ose Immunotherapeutics | Sposób wytwarzania stabilnej emulsji do dostarczania peptydów |
| RU2763798C1 (ru) * | 2017-12-23 | 2022-01-11 | Рубиус Терапьютикс, Инк. | Искусственные антигенпрезентирующие клетки и способы их применения |
| CN114853847B (zh) * | 2022-06-29 | 2022-09-27 | 中国农业大学 | 辣椒籽分离的寡肽ftle及其在预防或治疗癌症中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7579160B2 (en) * | 1998-03-18 | 2009-08-25 | Corixa Corporation | Methods for the detection of cervical cancer |
| AU2001279581A1 (en) * | 2000-09-06 | 2002-03-22 | Friederike Muller | Medicament comprising a dna sequence, which codes for the rna-binding koc protein, and comprising a koc protein or dna sequence of the koc promoter |
| ES2364670T3 (es) * | 2005-02-25 | 2011-09-12 | Oncotherapy Science, Inc. | Vacunas de péptidos para cánceres de pulmón que expresan polipéptidos ttk. |
| US10611818B2 (en) * | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| RS53782B1 (sr) * | 2008-10-01 | 2015-06-30 | Immatics Biotechnologies Gmbh | Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera |
-
2010
- 2010-11-26 TW TW099140933A patent/TW201124530A/zh unknown
- 2010-11-30 EP EP10834374.0A patent/EP2507256A4/en not_active Withdrawn
- 2010-11-30 MX MX2012006126A patent/MX2012006126A/es active IP Right Grant
- 2010-11-30 WO PCT/JP2010/006966 patent/WO2011067920A1/en not_active Ceased
- 2010-11-30 SG SG2012039277A patent/SG181107A1/en unknown
- 2010-11-30 JP JP2012524961A patent/JP2013511958A/ja active Pending
- 2010-11-30 CN CN201080062874.XA patent/CN102741271B/zh not_active Expired - Fee Related
- 2010-11-30 KR KR1020127017018A patent/KR20120099106A/ko not_active Withdrawn
- 2010-11-30 BR BR112012013139A patent/BR112012013139A2/pt not_active IP Right Cessation
- 2010-11-30 SG SG10201407944TA patent/SG10201407944TA/en unknown
- 2010-11-30 CA CA2782271A patent/CA2782271A1/en not_active Abandoned
- 2010-11-30 US US13/513,120 patent/US20120308590A1/en not_active Abandoned
- 2010-11-30 AU AU2010327878A patent/AU2010327878B2/en not_active Ceased
- 2010-11-30 RU RU2012127358/04A patent/RU2550695C2/ru not_active IP Right Cessation
-
2012
- 2012-05-24 IL IL219976A patent/IL219976A0/en unknown
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