JP2016511221A5 - - Google Patents
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- JP2016511221A5 JP2016511221A5 JP2015545547A JP2015545547A JP2016511221A5 JP 2016511221 A5 JP2016511221 A5 JP 2016511221A5 JP 2015545547 A JP2015545547 A JP 2015545547A JP 2015545547 A JP2015545547 A JP 2015545547A JP 2016511221 A5 JP2016511221 A5 JP 2016511221A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- amino acid
- peptide according
- apc
- ctl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 29
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 11
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 239000002157 polynucleotide Substances 0.000 claims 8
- 102000040430 polynucleotide Human genes 0.000 claims 8
- 108091033319 polynucleotide Proteins 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 6
- 239000000427 antigen Substances 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 3
- 210000001808 exosome Anatomy 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 102000025850 HLA-A2 Antigen Human genes 0.000 claims 1
- 108010074032 HLA-A2 Antigen Proteins 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361777334P | 2013-03-12 | 2013-03-12 | |
| US61/777,334 | 2013-03-12 | ||
| PCT/JP2014/001350 WO2014141683A1 (en) | 2013-03-12 | 2014-03-11 | Kntc2 peptides and vaccines containing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016511221A JP2016511221A (ja) | 2016-04-14 |
| JP2016511221A5 true JP2016511221A5 (https=) | 2017-04-13 |
| JP6295491B2 JP6295491B2 (ja) | 2018-03-20 |
Family
ID=51536362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545547A Active JP6295491B2 (ja) | 2013-03-12 | 2014-03-11 | Ｋｎｔｃ２ペプチドおよびそれを含むワクチン |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9597382B2 (https=) |
| EP (1) | EP2970944B1 (https=) |
| JP (1) | JP6295491B2 (https=) |
| KR (1) | KR102213574B1 (https=) |
| CN (1) | CN105164256B (https=) |
| AR (1) | AR095386A1 (https=) |
| AU (1) | AU2014232630B2 (https=) |
| BR (1) | BR112015021828A2 (https=) |
| CA (1) | CA2903139C (https=) |
| DK (1) | DK2970944T3 (https=) |
| ES (1) | ES2739693T3 (https=) |
| IL (1) | IL240701B (https=) |
| MX (1) | MX366365B (https=) |
| RU (1) | RU2671395C2 (https=) |
| SG (2) | SG10201707316WA (https=) |
| TW (1) | TWI658049B (https=) |
| WO (1) | WO2014141683A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2681899C (en) | 2007-03-27 | 2018-06-19 | Immunovia Ab | Methods for diagnosis of pancreatic adenocarcinoma, and biomarkers and arrays for use in the same |
| CA2974261A1 (en) * | 2015-02-09 | 2016-08-18 | Universite De Montreal | Novel minor histocompatibility antigens and uses thereof |
| ES2960205T3 (es) | 2015-06-16 | 2024-03-01 | Fond Citta Della Speranza Onlus | Vesículas extracelulares derivadas de células del linaje osteoblástico para uso terapéutico y diagnóstico |
| GB201516801D0 (en) * | 2015-09-22 | 2015-11-04 | Immunovia Ab | Method, array and use thereof |
| EP4649954A3 (en) | 2017-01-25 | 2025-12-17 | Ose Immunotherapeutics | Method for manufacturing a stable emulsion for peptide delivery |
| EP4036235A1 (en) * | 2018-02-15 | 2022-08-03 | National University Corporation Asahikawa Medical University | Cancer antigen peptide |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| US20230374140A1 (en) * | 2020-10-09 | 2023-11-23 | Memorial Sloan Kettering Cancer Center | Compositions targeting ndc80/mhc complexes and uses thereof |
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| TW200413725A (en) | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
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| US20070224201A1 (en) | 2002-10-02 | 2007-09-27 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
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| JP2006517788A (ja) | 2002-12-20 | 2006-08-03 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | １５９８６、２１８８、２０７４３、９１４８、９１５１、９７９１、４４２５２、１４１８４、４２４６１、８２０４、７９７０、２５５５２、２１６５７、２６４９２、２４１１、１５０８８、１９０５、２８８９９、６３３８０、３３９３５、１０４８０、１２６８６、２５５０１、１７６９４、１５７０１、５３０６２、４９９０８、２１６１２、３８９４９、６２１６、４６８６３、９２３５、２２０１、６９８５、９８８３、１２２３８、１８０５７、２１６１７、３９２２８、４９９２８、５４４７６、６２１１３、６４３１６、１２２６４、３２３６２、５８１９８、２８８７、３２０５、８５５７、９６００、９６９３、４４８６７、５３０５８、５５５５６、５７６５８、２２０８、１０２５２、１０３０２、１４２１８、３３８７７、１０３１７、１０４８５、２５９６４、１４８１５、１３６３、１３９７、１４８２７、２１７０８、３８０１、６４６９８、２１７９または１３２４９を使用する癌を処置するための方法および組成物 |
| EP1651775A2 (en) | 2003-06-18 | 2006-05-03 | Arcturus Bioscience, Inc. | Breast cancer survival and recurrence |
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| US11069427B2 (en) * | 2013-06-10 | 2021-07-20 | Iogenetics, Llc | Mathematical processes for determination of peptidase cleavage |
-
2014
- 2014-03-06 TW TW103107588A patent/TWI658049B/zh not_active IP Right Cessation
- 2014-03-11 MX MX2015012012A patent/MX366365B/es active IP Right Grant
- 2014-03-11 BR BR112015021828A patent/BR112015021828A2/pt not_active Application Discontinuation
- 2014-03-11 WO PCT/JP2014/001350 patent/WO2014141683A1/en not_active Ceased
- 2014-03-11 CA CA2903139A patent/CA2903139C/en active Active
- 2014-03-11 ES ES14763683T patent/ES2739693T3/es active Active
- 2014-03-11 DK DK14763683.1T patent/DK2970944T3/da active
- 2014-03-11 SG SG10201707316WA patent/SG10201707316WA/en unknown
- 2014-03-11 SG SG11201507236XA patent/SG11201507236XA/en unknown
- 2014-03-11 KR KR1020157027357A patent/KR102213574B1/ko not_active Expired - Fee Related
- 2014-03-11 CN CN201480022294.6A patent/CN105164256B/zh not_active Expired - Fee Related
- 2014-03-11 EP EP14763683.1A patent/EP2970944B1/en active Active
- 2014-03-11 AU AU2014232630A patent/AU2014232630B2/en not_active Ceased
- 2014-03-11 JP JP2015545547A patent/JP6295491B2/ja active Active
- 2014-03-11 RU RU2015143164A patent/RU2671395C2/ru active
- 2014-03-11 US US14/772,003 patent/US9597382B2/en active Active
- 2014-03-13 AR ARP140100928A patent/AR095386A1/es unknown
-
2015
- 2015-08-20 IL IL240701A patent/IL240701B/en unknown
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