JP2013502446A - １−［２−（２，４−ジメチル−フェニルスルファニル）−フェニル］ピペラジンの新規組成物 - Google Patents
１−［２−（２，４−ジメチル−フェニルスルファニル）−フェニル］ピペラジンの新規組成物 Download PDFInfo
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- JP2013502446A JP2013502446A JP2012525884A JP2012525884A JP2013502446A JP 2013502446 A JP2013502446 A JP 2013502446A JP 2012525884 A JP2012525884 A JP 2012525884A JP 2012525884 A JP2012525884 A JP 2012525884A JP 2013502446 A JP2013502446 A JP 2013502446A
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Addiction (AREA)
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- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
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| US23622309P | 2009-08-24 | 2009-08-24 | |
| DKPA200900950 | 2009-08-24 | ||
| US61/236,223 | 2009-08-24 | ||
| DKPA200900950 | 2009-08-24 | ||
| PCT/DK2010/050216 WO2011023194A2 (en) | 2009-08-24 | 2010-08-23 | New compositions of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine |
Publications (2)
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| JP2013502446A true JP2013502446A (ja) | 2013-01-24 |
| JP2013502446A5 JP2013502446A5 (enExample) | 2013-09-19 |
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Country Status (32)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200932233A (en) | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
| JP5787881B2 (ja) | 2010-04-30 | 2015-09-30 | 武田薬品工業株式会社 | 腸溶性錠剤 |
| WO2011136376A1 (ja) * | 2010-04-30 | 2011-11-03 | 武田薬品工業株式会社 | 腸溶性錠剤 |
| CN104146953A (zh) * | 2014-07-24 | 2014-11-19 | 李雪梅 | 一种氢溴酸沃替西汀注射液 |
| CN104610195B (zh) * | 2015-01-30 | 2017-06-27 | 上虞京新药业有限公司 | 沃替西汀的天冬氨酸盐或其水合物及其制备方法和用途 |
| JO3456B1 (ar) * | 2015-05-13 | 2020-07-05 | H Lundbeck As | فيروتيوكسيتين بيروجلوتامات |
| EP3184104B1 (en) | 2015-12-23 | 2018-09-12 | Hexal AG | Pharmaceutical composition of vortioxetine hydrobromide comprising vortioxetine hydrobromide in a polyethylene oxide matrix |
| EP3184102A1 (en) | 2015-12-23 | 2017-06-28 | Hexal AG | Pharmaceutical composition of vortioxetine hydrobromide comprising an inert core formed of an acidic reacting compound |
| MA45532A (fr) | 2016-07-01 | 2019-05-08 | H Lundbeck As | Schémas posologiques de la vortioxétine destinés à une apparition rapide de l'effet antidépresseur |
| WO2018065348A1 (en) | 2016-10-05 | 2018-04-12 | Hexal Ag | Novel enteric-coated tablet comprising vortioxetine |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| CN112006995A (zh) * | 2020-08-14 | 2020-12-01 | 石药集团中奇制药技术（石家庄）有限公司 | 一种氢溴酸伏硫西汀片的制备方法 |
| CN113350348B (zh) * | 2020-11-05 | 2022-03-01 | 东南大学 | 一种1-二苯甲基-4-甲基哌嗪类化合物在制备保护肠道屏障完整性药物中的应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11509539A (ja) * | 1995-07-20 | 1999-08-24 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | パロキセチン制御放出組成物 |
| JP2005505585A (ja) * | 2001-10-04 | 2005-02-24 | ハー・ルンドベック・アクチエゼルスカベット | セロトニン再取り込み阻害剤としてのフェニル−ピペラジン誘導体 |
| JP2009503057A (ja) * | 2005-08-02 | 2009-01-29 | ルピン・リミテッド | 選択的セロトニン再取り込み阻害剤の新規の制御放出組成物 |
| JP2011503125A (ja) * | 2007-11-13 | 2011-01-27 | ハー・ルンドベック・アクチエゼルスカベット | Ｓｅｒｔ、５−ｈｔ３および５−ｈｔ１ａの組み合わせた活性を有する化合物の治療的使用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6866146B2 (en) | 2001-10-09 | 2005-03-15 | Christian M. Heesch | Protective case for string instruments |
| JP2008524332A (ja) * | 2004-12-20 | 2008-07-10 | コレジウム ファーマシューティカル， インク． | 睡眠傷害のための医薬組成物 |
| ES2493466T3 (es) * | 2005-05-12 | 2014-09-11 | Abbvie Bahamas Ltd. | Promotores de la apoptosis |
| MY150647A (en) * | 2006-06-16 | 2014-02-14 | Lundbeck & Co As H | 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment |
| TW200848411A (en) | 2007-03-20 | 2008-12-16 | Lundbeck & Co As H | Novel therapeutic uses of 1-[2-(2, 4-dimethylphenylsulfanyl)phenyl]-piperazine |
-
2010
- 2010-08-23 CA CA2769872A patent/CA2769872A1/en not_active Abandoned
- 2010-08-23 UA UAA201203101A patent/UA105057C2/uk unknown
- 2010-08-23 BR BR112012003280A patent/BR112012003280A2/pt not_active IP Right Cessation
- 2010-08-23 GE GEAP201012633A patent/GEP20135950B/en unknown
- 2010-08-23 ME MEP-2013-99A patent/ME01602B/me unknown
- 2010-08-23 WO PCT/DK2010/050216 patent/WO2011023194A2/en not_active Ceased
- 2010-08-23 EP EP10805414.9A patent/EP2470166B1/en not_active Revoked
- 2010-08-23 SI SI201030343T patent/SI2470166T1/sl unknown
- 2010-08-23 ES ES10805414T patent/ES2427628T3/es active Active
- 2010-08-23 JP JP2012525884A patent/JP2013502446A/ja active Pending
- 2010-08-23 US US13/388,750 patent/US20120189697A1/en not_active Abandoned
- 2010-08-23 MX MX2012002199A patent/MX2012002199A/es active IP Right Grant
- 2010-08-23 KR KR1020127004405A patent/KR20120065328A/ko not_active Withdrawn
- 2010-08-23 AU AU2010289022A patent/AU2010289022B2/en not_active Ceased
- 2010-08-23 DK DK10805414.9T patent/DK2470166T3/da active
- 2010-08-23 NZ NZ598083A patent/NZ598083A/xx not_active IP Right Cessation
- 2010-08-23 PT PT108054149T patent/PT2470166E/pt unknown
- 2010-08-23 SG SG2012008868A patent/SG178325A1/en unknown
- 2010-08-23 EA EA201290116A patent/EA021321B1/ru not_active IP Right Cessation
- 2010-08-23 PL PL10805414T patent/PL2470166T3/pl unknown
- 2010-08-23 RS RS20130404A patent/RS52959B/sr unknown
- 2010-08-23 CN CN2010800376999A patent/CN102639117A/zh active Pending
- 2010-08-23 HR HRP20130819AT patent/HRP20130819T1/hr unknown
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2012
- 2012-01-25 TN TNP2012000038A patent/TN2012000038A1/en unknown
- 2012-02-02 IL IL217914A patent/IL217914A0/en unknown
- 2012-02-07 CR CR20120058A patent/CR20120058A/es unknown
- 2012-02-17 CO CO12028578A patent/CO6612204A2/es not_active Application Discontinuation
- 2012-02-22 CL CL2012000457A patent/CL2012000457A1/es unknown
- 2012-02-23 ZA ZA2012/01360A patent/ZA201201360B/en unknown
- 2012-02-23 DO DO2012000050A patent/DOP2012000050A/es unknown
- 2012-03-21 MA MA34709A patent/MA33598B1/fr unknown
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2013
- 2013-09-30 SM SM201300108T patent/SMT201300108B/xx unknown
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2015
- 2015-02-04 US US14/613,693 patent/US20150150867A1/en not_active Abandoned
- 2015-10-19 US US14/886,333 patent/US20160256398A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11509539A (ja) * | 1995-07-20 | 1999-08-24 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | パロキセチン制御放出組成物 |
| JP2005505585A (ja) * | 2001-10-04 | 2005-02-24 | ハー・ルンドベック・アクチエゼルスカベット | セロトニン再取り込み阻害剤としてのフェニル−ピペラジン誘導体 |
| JP2009503057A (ja) * | 2005-08-02 | 2009-01-29 | ルピン・リミテッド | 選択的セロトニン再取り込み阻害剤の新規の制御放出組成物 |
| JP2011503125A (ja) * | 2007-11-13 | 2011-01-27 | ハー・ルンドベック・アクチエゼルスカベット | Ｓｅｒｔ、５−ｈｔ３および５−ｈｔ１ａの組み合わせた活性を有する化合物の治療的使用 |
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