JP2013500292A5 - - Google Patents
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- JP2013500292A5 JP2013500292A5 JP2012522042A JP2012522042A JP2013500292A5 JP 2013500292 A5 JP2013500292 A5 JP 2013500292A5 JP 2012522042 A JP2012522042 A JP 2012522042A JP 2012522042 A JP2012522042 A JP 2012522042A JP 2013500292 A5 JP2013500292 A5 JP 2013500292A5
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- JP
- Japan
- Prior art keywords
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims description 24
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims description 8
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims description 6
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims description 6
- 239000000314 lubricant Substances 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 6
- -1 brighteners Substances 0.000 claims description 5
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- 229920000642 polymer Polymers 0.000 claims description 4
- 239000005639 Lauric acid Substances 0.000 claims description 3
- 235000021314 Palmitic acid Nutrition 0.000 claims description 3
- 235000021355 Stearic acid Nutrition 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 239000002537 cosmetic Substances 0.000 claims description 3
- 235000015872 dietary supplement Nutrition 0.000 claims description 3
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims description 3
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 3
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- FIWQZURFGYXCEO-UHFFFAOYSA-M sodium;decanoate Chemical compound [Na+].CCCCCCCCCC([O-])=O FIWQZURFGYXCEO-UHFFFAOYSA-M 0.000 claims description 3
- 239000008117 stearic acid Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 239000003963 antioxidant agent Substances 0.000 claims description 2
- 239000011230 binding agent Substances 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims description 2
- 239000003623 enhancer Substances 0.000 claims description 2
- 239000000796 flavoring agent Substances 0.000 claims description 2
- 239000003205 fragrance Substances 0.000 claims description 2
- 150000002763 monocarboxylic acids Chemical class 0.000 claims description 2
- 230000035515 penetration Effects 0.000 claims description 2
- 239000000049 pigment Substances 0.000 claims description 2
- 239000004014 plasticizer Substances 0.000 claims description 2
- 239000011148 porous material Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000003381 stabilizer Substances 0.000 claims description 2
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 claims description 2
- KBPLFHHGFOOTCA-UHFFFAOYSA-N 1-Octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 229920001577 copolymer Polymers 0.000 claims 3
- 239000006185 dispersion Substances 0.000 claims 3
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 2
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical compound CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 2
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 2
- 125000001302 tertiary amino group Chemical group 0.000 claims 2
- 238000005550 wet granulation Methods 0.000 claims 2
- JKNCOURZONDCGV-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-methylprop-2-enoate Chemical compound CN(C)CCOC(=O)C(C)=C JKNCOURZONDCGV-UHFFFAOYSA-N 0.000 claims 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 1
- 238000007908 dry granulation Methods 0.000 claims 1
- 150000002191 fatty alcohols Chemical class 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000007909 melt granulation Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 claims 1
- 229960002446 octanoic acid Drugs 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 238000001694 spray drying Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 description 5
- 235000002639 sodium chloride Nutrition 0.000 description 5
- 239000000725 suspension Substances 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 229920003149 Eudragit® E 100 Polymers 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 description 1
- 239000008116 calcium stearate Substances 0.000 description 1
- 235000013539 calcium stearate Nutrition 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Substances [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000006082 mold release agent Substances 0.000 description 1
- 239000012875 nonionic emulsifier Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2009059861 | 2009-07-30 | ||
| EPPCT/EP2009/059861 | 2009-07-30 | ||
| PCT/EP2010/053447 WO2011012335A1 (en) | 2009-07-30 | 2010-03-17 | Powdery or granulated composition comprising a copolymer, a salt of a fatty monocarboxylic acid and a fatty monocarboxylic acid and/or a fatty alcohol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500292A JP2013500292A (ja) | 2013-01-07 |
| JP2013500292A5 true JP2013500292A5 (https=) | 2013-05-16 |
| JP5623524B2 JP5623524B2 (ja) | 2014-11-12 |
Family
ID=41827021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012522042A Expired - Fee Related JP5623524B2 (ja) | 2009-07-30 | 2010-03-17 | コポリマー、脂肪モノカルボン酸の塩および脂肪モノカルボン酸および／または脂肪アルコールを含む粉末状または粒状組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20120093903A1 (https=) |
| JP (1) | JP5623524B2 (https=) |
| KR (1) | KR101664523B1 (https=) |
| CN (1) | CN102471524B (https=) |
| BR (1) | BR112012008132A8 (https=) |
| CA (1) | CA2769252C (https=) |
| ES (1) | ES2424492T3 (https=) |
| IL (1) | IL216352A (https=) |
| MX (1) | MX2012001177A (https=) |
| WO (1) | WO2011012335A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2015681B1 (en) | 2006-05-03 | 2018-03-28 | Datascope Corp. | Tissue closure device |
| JP5528186B2 (ja) * | 2010-04-12 | 2014-06-25 | 三井化学株式会社 | 粉体樹脂組成物、それを用いたポリマーアロイ、およびこれらの製造方法 |
| US8962064B2 (en) | 2011-02-28 | 2015-02-24 | Basf Se | Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms |
| EP2681263B1 (de) * | 2011-02-28 | 2018-09-12 | Basf Se | Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen |
| RU2523799C1 (ru) * | 2011-12-20 | 2014-07-27 | Чайна Петролеум Энд Кемикал Корпорейшн | Добавка и способ для обрыва полимеризации и/или снижения вязкости раствора полимера |
| CA2886626A1 (en) | 2012-09-28 | 2014-04-03 | Evonik Industries Ag | Process for preparing aqueous dispersions |
| EP2922907A1 (en) * | 2012-11-22 | 2015-09-30 | Evonik Röhm GmbH | Process for preparing a granulated product from a powder composition |
| EP2801349A1 (en) | 2013-05-06 | 2014-11-12 | Siegfried AG | Oral Pharmaceutical Formulation |
| WO2015077356A1 (en) | 2013-11-19 | 2015-05-28 | Wheeler William K | Fastener applicator with interlock |
| US11653928B2 (en) | 2018-03-28 | 2023-05-23 | Datascope Corp. | Device for atrial appendage exclusion |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3106449A1 (de) | 1981-02-20 | 1982-09-09 | Röhm GmbH, 6100 Darmstadt | "in magensaft loesliche oder quellbare ueberzugsmasse und ihre verwendung in einem verfahren zum ueberziehen von arzneiformen" |
| DE3581428D1 (de) | 1984-06-13 | 1991-02-28 | Roehm Gmbh | Verfahren zum ueberziehen von arzneiformen. |
| WO1994008610A1 (en) | 1992-10-16 | 1994-04-28 | Smithkline Beecham Corporation | Pharmaceutical emulsion compositions |
| DE19958007A1 (de) * | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| WO2002067906A1 (de) | 2001-02-27 | 2002-09-06 | Röhm GmbH & Co. KG | Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität |
| DE10260921A1 (de) * | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln |
-
2010
- 2010-03-17 BR BR112012008132A patent/BR112012008132A8/pt not_active Application Discontinuation
- 2010-03-17 ES ES10709006T patent/ES2424492T3/es active Active
- 2010-03-17 US US13/376,529 patent/US20120093903A1/en not_active Abandoned
- 2010-03-17 CN CN201080028694.XA patent/CN102471524B/zh not_active Expired - Fee Related
- 2010-03-17 MX MX2012001177A patent/MX2012001177A/es active IP Right Grant
- 2010-03-17 CA CA2769252A patent/CA2769252C/en active Active
- 2010-03-17 KR KR1020127002436A patent/KR101664523B1/ko not_active Expired - Fee Related
- 2010-03-17 WO PCT/EP2010/053447 patent/WO2011012335A1/en not_active Ceased
- 2010-03-17 JP JP2012522042A patent/JP5623524B2/ja not_active Expired - Fee Related
-
2011
- 2011-11-14 IL IL216352A patent/IL216352A/en active IP Right Grant
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