JP2013173796A5 - - Google Patents
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- Publication number
- JP2013173796A5 JP2013173796A5 JP2013117401A JP2013117401A JP2013173796A5 JP 2013173796 A5 JP2013173796 A5 JP 2013173796A5 JP 2013117401 A JP2013117401 A JP 2013117401A JP 2013117401 A JP2013117401 A JP 2013117401A JP 2013173796 A5 JP2013173796 A5 JP 2013173796A5
- Authority
- JP
- Japan
- Prior art keywords
- chronic skin
- connexin
- polynucleotide
- pluronic
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001684 chronic effect Effects 0.000 claims 22
- 239000000203 mixture Substances 0.000 claims 21
- 206010072170 Skin wound Diseases 0.000 claims 20
- 102000040430 polynucleotide Human genes 0.000 claims 17
- 108091033319 polynucleotide Proteins 0.000 claims 17
- 239000002157 polynucleotide Substances 0.000 claims 17
- 229920001992 poloxamer 407 Polymers 0.000 claims 14
- 238000011200 topical administration Methods 0.000 claims 8
- 206010052428 Wound Diseases 0.000 claims 6
- 208000027418 Wounds and injury Diseases 0.000 claims 6
- 208000000558 Varicose Ulcer Diseases 0.000 claims 4
- 230000037396 body weight Effects 0.000 claims 4
- 208000008960 Diabetic foot Diseases 0.000 claims 2
- 206010056340 Diabetic ulcer Diseases 0.000 claims 2
- 206010040943 Skin Ulcer Diseases 0.000 claims 2
- 229940046166 oligodeoxynucleotide Drugs 0.000 claims 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87440406P | 2006-12-11 | 2006-12-11 | |
| US60/874,404 | 2006-12-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541370A Division JP5431949B2 (ja) | 2006-12-11 | 2007-12-11 | 減損した創傷治癒の組成物としての抗コネキシンポリヌクレオチド |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015000248A Division JP2015063565A (ja) | 2006-12-11 | 2015-01-05 | 減損した創傷治癒の組成物としての抗コネキシンポリヌクレオチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013173796A JP2013173796A (ja) | 2013-09-05 |
| JP2013173796A5 true JP2013173796A5 (enExample) | 2014-04-10 |
| JP5911454B2 JP5911454B2 (ja) | 2016-04-27 |
Family
ID=39386432
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541370A Expired - Fee Related JP5431949B2 (ja) | 2006-12-11 | 2007-12-11 | 減損した創傷治癒の組成物としての抗コネキシンポリヌクレオチド |
| JP2013117401A Expired - Fee Related JP5911454B2 (ja) | 2006-12-11 | 2013-06-03 | 減損した創傷治癒の組成物としての抗コネキシンポリヌクレオチド |
| JP2015000248A Pending JP2015063565A (ja) | 2006-12-11 | 2015-01-05 | 減損した創傷治癒の組成物としての抗コネキシンポリヌクレオチド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541370A Expired - Fee Related JP5431949B2 (ja) | 2006-12-11 | 2007-12-11 | 減損した創傷治癒の組成物としての抗コネキシンポリヌクレオチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015000248A Pending JP2015063565A (ja) | 2006-12-11 | 2015-01-05 | 減損した創傷治癒の組成物としての抗コネキシンポリヌクレオチド |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US8063023B2 (enExample) |
| EP (3) | EP2543378A1 (enExample) |
| JP (3) | JP5431949B2 (enExample) |
| KR (1) | KR101521306B1 (enExample) |
| CN (2) | CN103520197B (enExample) |
| AU (1) | AU2007333535B2 (enExample) |
| BR (1) | BRPI0721094A2 (enExample) |
| CA (1) | CA2672220A1 (enExample) |
| DK (1) | DK2101791T3 (enExample) |
| ES (1) | ES2527131T3 (enExample) |
| PL (1) | PL2101791T3 (enExample) |
| PT (1) | PT2101791E (enExample) |
| RU (1) | RU2521329C2 (enExample) |
| SI (1) | SI2101791T1 (enExample) |
| WO (1) | WO2008073479A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150004906A (ko) | 2005-02-03 | 2015-01-13 | 코다 테라퓨틱스 (엔지) 리미티드 | 항-코넥신 화합물 및 그의 용도 |
| KR20150072458A (ko) | 2006-11-15 | 2015-06-29 | 코다 테라퓨틱스, 인크. | 상처 치유를 위한 개선 방법 및 조성물 |
| RU2521329C2 (ru) | 2006-12-11 | 2014-06-27 | Коуда Терапьютикс, Инк. | Композиции и способы лечения плохо заживающих ран |
| US20080249044A1 (en) * | 2007-04-03 | 2008-10-09 | Masaya Tanaka | Nucleic acid external skin formulation |
| JP2011506447A (ja) * | 2007-12-11 | 2011-03-03 | コーダ セラピューティクス， インコーポレイテッド | 損傷した創傷治癒組成物および治療 |
| AU2008335717A1 (en) * | 2007-12-11 | 2009-06-18 | Coda Therapeutics, Inc. | Impaired wound healing compositions and treatments |
| US8975237B2 (en) | 2007-12-21 | 2015-03-10 | Coda Therapeutics, Inc. | Treatment of fibrotic conditions |
| AU2008343756A1 (en) * | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Use of anti-connexin polypeptide agent in combination with anti-connexin polynucleotide agent for the treatment of fibrotic conditions |
| WO2012076985A2 (en) * | 2010-12-06 | 2012-06-14 | The University Of British Columbia | Granzyme b inhibitor compositions, methods and uses for promoting wound healing |
| GB201117538D0 (en) * | 2011-10-11 | 2011-11-23 | Royal Veterinary College The | Methods |
| KR102038948B1 (ko) | 2012-03-01 | 2019-11-26 | 퍼스트스트링 리서치 인코포레이티드 | 알파 코넥신 c-말단 (act) 펩타이드를 포함하는 국소 겔 |
| CN104736709A (zh) * | 2012-03-27 | 2015-06-24 | 科达治疗公司 | 基于钙粘蛋白调节的组合物和治疗 |
| US9156896B2 (en) | 2013-03-15 | 2015-10-13 | Coda Therapeutics, Inc. | Wound healing compositions and treatments |
| CA2941140A1 (en) * | 2014-03-14 | 2015-09-17 | Coda Therapeutics | Treatment of resistant lesions |
| EP4491184A3 (en) | 2014-08-22 | 2025-03-26 | Auckland Uniservices Limited | Channel modulators |
| CN113694077A (zh) * | 2015-08-13 | 2021-11-26 | 索马根尼科斯公司 | 用于伤口愈合的短小发夹rna与微rna的组合物以及方法 |
| EP3518847B1 (en) * | 2016-09-27 | 2023-03-01 | Smith & Nephew plc | Wound closure devices with dissolvable portions |
| CA3061738A1 (en) | 2017-04-28 | 2018-11-01 | Auckland Uniservices Limited | Methods of treatment and novel constructs |
| CN108588075A (zh) * | 2018-05-03 | 2018-09-28 | 天德悦（北京）生物科技有限责任公司 | 人Cx43基因干扰序列、shRNA-Cx43病毒及低表达Cx43蛋白的细胞系 |
| MX2023004631A (es) | 2020-10-22 | 2023-07-20 | Xequel Bio Inc | Formulaciones peptidicas y usos oftalmicos de las mismas. |
| RU2754383C1 (ru) * | 2020-12-07 | 2021-09-01 | Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Эндокринологии" Министерства Здравоохранения Российской Федерации (Фгбу "Нмиц Эндокринологии" Минздрава России) | Способ лечения неинфицированного послеоперационного раневого дефекта стопы при отсутствии признаков критической ишемии конечности у больных с нейропатической и нейроишемической формой синдрома диабетической стопы |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0539594Y2 (enExample) | 1988-08-05 | 1993-10-07 | ||
| US5004810A (en) | 1988-09-30 | 1991-04-02 | Schering Corporation | Antiviral oligomers |
| US5166195A (en) | 1990-05-11 | 1992-11-24 | Isis Pharmaceuticals, Inc. | Antisense inhibitors of the human immunodeficiency virus phosphorothioate oligonucleotides |
| GB9425930D0 (en) | 1994-12-22 | 1995-02-22 | Procter & Gamble | Silicone compositions |
| EP0950060A4 (en) | 1996-12-02 | 2000-07-05 | Dyad Pharmaceutical Corp | COUNTERSTRAIN INHIBITION OF HUMAN ADHESION MOLECULES |
| RU2147240C1 (ru) * | 1998-02-16 | 2000-04-10 | Рязанский областной клинический кожно-венерологический диспансер | Препарат для лечения длительно незаживающих инфицированных язв и ран |
| EP1621212B1 (en) * | 1999-01-27 | 2011-11-16 | Coda Therapeutics, Inc. | Formulations comprising antisense nucleotides to connexins |
| US7250397B2 (en) | 2000-02-23 | 2007-07-31 | Zealand Pharma A/S | Antiarrhythmic peptides |
| US20050119211A1 (en) * | 2001-05-18 | 2005-06-02 | Sirna Therapeutics, Inc. | RNA mediated inhibition connexin gene expression using short interfering nucleic acid (siNA) |
| WO2003032964A2 (en) | 2001-10-17 | 2003-04-24 | University Of Wales College Of Medecine | Gap junctions and endothelial-derived hyperpolarizing factor (edhf) |
| CN1939529A (zh) | 2002-01-29 | 2007-04-04 | Wyeth公司 | 用于调节连接蛋白半通道的组合物和方法 |
| KR20180037067A (ko) * | 2003-12-03 | 2018-04-10 | 코다 테라퓨틱스 (엔지) 리미티드 | 코넥신에 표적화된 안티센스 화합물 및 그의 사용 방법 |
| DE102004027422A1 (de) | 2004-06-04 | 2005-12-29 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung zur Aufnahme von Blut und Abtrennung von Blutbestandteilen |
| HUE038099T2 (hu) | 2004-12-21 | 2018-09-28 | Musc Found For Res Dev | Kompozíciók és módszerek sebgyógyulás és szöveti regeneráció elõsegítésére |
| KR20150004906A (ko) * | 2005-02-03 | 2015-01-13 | 코다 테라퓨틱스 (엔지) 리미티드 | 항-코넥신 화합물 및 그의 용도 |
| KR20150072458A (ko) | 2006-11-15 | 2015-06-29 | 코다 테라퓨틱스, 인크. | 상처 치유를 위한 개선 방법 및 조성물 |
| RU2521329C2 (ru) | 2006-12-11 | 2014-06-27 | Коуда Терапьютикс, Инк. | Композиции и способы лечения плохо заживающих ран |
| KR20150028856A (ko) | 2007-05-31 | 2015-03-16 | 안테리오스, 인코퍼레이티드 | 핵산 나노입자 및 이의 용도 |
| JP2011506447A (ja) | 2007-12-11 | 2011-03-03 | コーダ セラピューティクス， インコーポレイテッド | 損傷した創傷治癒組成物および治療 |
| AU2008335717A1 (en) | 2007-12-11 | 2009-06-18 | Coda Therapeutics, Inc. | Impaired wound healing compositions and treatments |
-
2007
- 2007-12-11 RU RU2009126594/15A patent/RU2521329C2/ru not_active IP Right Cessation
- 2007-12-11 BR BRPI0721094-9A2A patent/BRPI0721094A2/pt not_active Application Discontinuation
- 2007-12-11 PT PT07853353T patent/PT2101791E/pt unknown
- 2007-12-11 US US12/001,498 patent/US8063023B2/en not_active Expired - Fee Related
- 2007-12-11 AU AU2007333535A patent/AU2007333535B2/en not_active Ceased
- 2007-12-11 ES ES07853353.6T patent/ES2527131T3/es active Active
- 2007-12-11 EP EP20120182489 patent/EP2543378A1/en not_active Ceased
- 2007-12-11 JP JP2009541370A patent/JP5431949B2/ja not_active Expired - Fee Related
- 2007-12-11 EP EP20070853353 patent/EP2101791B1/en not_active Not-in-force
- 2007-12-11 DK DK07853353.6T patent/DK2101791T3/en active
- 2007-12-11 EP EP20120182487 patent/EP2543377A1/en not_active Ceased
- 2007-12-11 CA CA002672220A patent/CA2672220A1/en not_active Abandoned
- 2007-12-11 PL PL07853353T patent/PL2101791T3/pl unknown
- 2007-12-11 KR KR1020097014484A patent/KR101521306B1/ko not_active Expired - Fee Related
- 2007-12-11 WO PCT/US2007/025446 patent/WO2008073479A2/en not_active Ceased
- 2007-12-11 SI SI200731570T patent/SI2101791T1/sl unknown
- 2007-12-11 CN CN201310392821.XA patent/CN103520197B/zh not_active Expired - Fee Related
- 2007-12-11 CN CN200780051207.XA patent/CN101835476B/zh not_active Expired - Fee Related
-
2011
- 2011-11-11 US US13/295,020 patent/US8685940B2/en not_active Expired - Fee Related
-
2013
- 2013-02-11 US US13/764,674 patent/US9029339B2/en not_active Expired - Fee Related
- 2013-06-03 JP JP2013117401A patent/JP5911454B2/ja not_active Expired - Fee Related
-
2015
- 2015-01-05 JP JP2015000248A patent/JP2015063565A/ja active Pending
- 2015-05-11 US US14/709,382 patent/US9637745B2/en not_active Expired - Fee Related
-
2017
- 2017-05-01 US US15/583,898 patent/US20170240905A1/en not_active Abandoned
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