JP2013137267A - マイクロチップ及びマイクロチップ型微小粒子測定装置 - Google Patents

マイクロチップ及びマイクロチップ型微小粒子測定装置 Download PDF

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Publication number
JP2013137267A
JP2013137267A JP2011288862A JP2011288862A JP2013137267A JP 2013137267 A JP2013137267 A JP 2013137267A JP 2011288862 A JP2011288862 A JP 2011288862A JP 2011288862 A JP2011288862 A JP 2011288862A JP 2013137267 A JP2013137267 A JP 2013137267A
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Prior art keywords
microchip
laser
incident
incident surface
scattered light
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JP2011288862A
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English (en)
Japanese (ja)
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JP2013137267A5 (enExample
Inventor
Katsuhiro Seo
勝弘 瀬尾
Koichi Tsukihara
浩一 月原
Yoshiki Okamoto
好喜 岡本
Shunpei Suzuki
俊平 鈴木
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Sony Corp
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Sony Corp
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Publication date
Application filed by Sony Corp filed Critical Sony Corp
Priority to JP2011288862A priority Critical patent/JP2013137267A/ja
Priority to CN201280063605.4A priority patent/CN103998916A/zh
Priority to PCT/JP2012/006846 priority patent/WO2013099078A1/en
Priority to EP12812397.3A priority patent/EP2798331A1/en
Priority to US14/367,001 priority patent/US20140370586A1/en
Publication of JP2013137267A publication Critical patent/JP2013137267A/ja
Publication of JP2013137267A5 publication Critical patent/JP2013137267A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1452—Adjustment of focus; Alignment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/067—Electro-optic, magneto-optic, acousto-optic elements

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2011288862A 2011-12-28 2011-12-28 マイクロチップ及びマイクロチップ型微小粒子測定装置 Pending JP2013137267A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2011288862A JP2013137267A (ja) 2011-12-28 2011-12-28 マイクロチップ及びマイクロチップ型微小粒子測定装置
CN201280063605.4A CN103998916A (zh) 2011-12-28 2012-10-25 微芯片和微芯片型细微粒测量装置
PCT/JP2012/006846 WO2013099078A1 (en) 2011-12-28 2012-10-25 Microchip and microchip-type fine-particle measuring device
EP12812397.3A EP2798331A1 (en) 2011-12-28 2012-10-25 Microchip and microchip-type fine-particle measuring device
US14/367,001 US20140370586A1 (en) 2011-12-28 2012-10-25 Microchip and microchip-type fine-particle measuring device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011288862A JP2013137267A (ja) 2011-12-28 2011-12-28 マイクロチップ及びマイクロチップ型微小粒子測定装置

Publications (2)

Publication Number Publication Date
JP2013137267A true JP2013137267A (ja) 2013-07-11
JP2013137267A5 JP2013137267A5 (enExample) 2015-01-22

Family

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Family Applications (1)

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JP2011288862A Pending JP2013137267A (ja) 2011-12-28 2011-12-28 マイクロチップ及びマイクロチップ型微小粒子測定装置

Country Status (5)

Country Link
US (1) US20140370586A1 (enExample)
EP (1) EP2798331A1 (enExample)
JP (1) JP2013137267A (enExample)
CN (1) CN103998916A (enExample)
WO (1) WO2013099078A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
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JP2020027002A (ja) * 2018-08-10 2020-02-20 東ソー株式会社 粒子検出装置
JP2021503608A (ja) * 2017-09-21 2021-02-12 ビーアイティー グループ フランスＢｉｔ Ｇｒｏｕｐ Ｆｒａｎｃｅ 落射蛍光測定用の光学フローサイトメータ

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US20170227447A1 (en) * 2014-08-06 2017-08-10 Beckman Coulter, Inc. Evaluation of multi-peak events using a flow cytometer
EP3311135B1 (en) * 2015-06-17 2023-11-01 Becton, Dickinson and Company Optical detector scatter cap assembly having a removable scatter bar and methods of using the same
WO2017117461A1 (en) 2015-12-30 2017-07-06 Bio-Rad Laboratories, Inc. Optical detection system for particles
US10060847B2 (en) 2015-12-30 2018-08-28 Bio-Rad Laboratories, Inc. Detection and signal processing system for particle assays
JP6583525B2 (ja) * 2016-02-23 2019-10-02 株式会社島津製作所 顕微分析装置
EP3574305A1 (en) * 2017-01-30 2019-12-04 Miltenyi Biotec B.V. & Co. KG Printed flow cell for photometer
EP3654018B1 (en) 2017-07-11 2023-06-21 Hamamatsu Photonics K.K. Sample observation device and sample observation method
EP3655759A1 (en) * 2017-07-19 2020-05-27 Fundació Institut de Ciències Fotòniques A hand-held microfluidic detection device
JP7439438B2 (ja) * 2019-09-30 2024-02-28 ソニーグループ株式会社 生体粒子分析用マイクロチップ、生体粒子分析装置、微小粒子分析用マイクロチップ、及び微小粒子分析装置
WO2021218463A1 (zh) * 2020-04-26 2021-11-04 青岛海信宽带多媒体技术有限公司 一种光模块
CN114632557B (zh) * 2020-12-16 2024-05-28 合肥京东方光电科技有限公司 一种微流控芯片的对置基板及微流控芯片

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JP2003279466A (ja) * 2002-03-20 2003-10-02 Nikkiso Co Ltd 粒度センサー用測定セル
JP2005156553A (ja) * 2003-11-25 2005-06-16 Wyatt Technol Corp 屈折計セル、その第２のチャンバの角度を判定する方法、液体の屈折率および屈折率差を測定するための方法
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JP2011503516A (ja) * 2006-09-18 2011-01-27 ユニヴァーシティ オブ ワシントン 光マイクロトモグラフィのための焦点面追跡
WO2011028818A2 (en) * 2009-09-01 2011-03-10 Trustees Of Boston University High throughput multichannel reader and uses thereof
US20110134420A1 (en) * 2008-07-22 2011-06-09 Daisuke Matsumoto Microchip and Analyzing Apparatus
JP2011145185A (ja) * 2010-01-15 2011-07-28 Sony Corp 流路構造、マイクロチップ及び送流方法
JP2011149822A (ja) * 2010-01-21 2011-08-04 Sony Corp 光学的測定装置及び光学的測定方法

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JP4661942B2 (ja) * 2008-05-13 2011-03-30 ソニー株式会社 マイクロチップとその流路構造
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JP5487638B2 (ja) 2009-02-17 2014-05-07 ソニー株式会社 微小粒子分取のための装置及びマイクロチップ
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JPH11513486A (ja) * 1995-09-27 1999-11-16 ユニバーシティ オブ ワシントン シリコンマイクロチャネル光学フローサイトメータ
JP2003279466A (ja) * 2002-03-20 2003-10-02 Nikkiso Co Ltd 粒度センサー用測定セル
JP2005156553A (ja) * 2003-11-25 2005-06-16 Wyatt Technol Corp 屈折計セル、その第２のチャンバの角度を判定する方法、液体の屈折率および屈折率差を測定するための方法
JP2011503516A (ja) * 2006-09-18 2011-01-27 ユニヴァーシティ オブ ワシントン 光マイクロトモグラフィのための焦点面追跡
JP2009204509A (ja) * 2008-02-28 2009-09-10 Fujifilm Corp 検査チップ、これを用いるセンシング装置および物質検出方法
US20110134420A1 (en) * 2008-07-22 2011-06-09 Daisuke Matsumoto Microchip and Analyzing Apparatus
WO2011028818A2 (en) * 2009-09-01 2011-03-10 Trustees Of Boston University High throughput multichannel reader and uses thereof
JP2011145185A (ja) * 2010-01-15 2011-07-28 Sony Corp 流路構造、マイクロチップ及び送流方法
JP2011149822A (ja) * 2010-01-21 2011-08-04 Sony Corp 光学的測定装置及び光学的測定方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021503608A (ja) * 2017-09-21 2021-02-12 ビーアイティー グループ フランスＢｉｔ Ｇｒｏｕｐ Ｆｒａｎｃｅ 落射蛍光測定用の光学フローサイトメータ
JP2020027002A (ja) * 2018-08-10 2020-02-20 東ソー株式会社 粒子検出装置
JP7165346B2 (ja) 2018-08-10 2022-11-04 東ソー株式会社 粒子検出装置

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Publication number Publication date
US20140370586A1 (en) 2014-12-18
CN103998916A (zh) 2014-08-20
EP2798331A1 (en) 2014-11-05
WO2013099078A1 (en) 2013-07-04

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