CN103998916A - 微芯片和微芯片型细微粒测量装置 - Google Patents

微芯片和微芯片型细微粒测量装置 Download PDF

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Publication number
CN103998916A
CN103998916A CN201280063605.4A CN201280063605A CN103998916A CN 103998916 A CN103998916 A CN 103998916A CN 201280063605 A CN201280063605 A CN 201280063605A CN 103998916 A CN103998916 A CN 103998916A
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CN
China
Prior art keywords
microchip
light
incident
detector
light source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280063605.4A
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English (en)
Chinese (zh)
Inventor
濑尾胜弘
月原浩一
冈本好喜
铃木俊平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Corp
Original Assignee
Sony Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Corp filed Critical Sony Corp
Publication of CN103998916A publication Critical patent/CN103998916A/zh
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1452—Adjustment of focus; Alignment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/067—Electro-optic, magneto-optic, acousto-optic elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201280063605.4A 2011-12-28 2012-10-25 微芯片和微芯片型细微粒测量装置 Pending CN103998916A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011288862A JP2013137267A (ja) 2011-12-28 2011-12-28 マイクロチップ及びマイクロチップ型微小粒子測定装置
JP2011-288862 2011-12-28
PCT/JP2012/006846 WO2013099078A1 (en) 2011-12-28 2012-10-25 Microchip and microchip-type fine-particle measuring device

Publications (1)

Publication Number Publication Date
CN103998916A true CN103998916A (zh) 2014-08-20

Family

ID=47520211

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280063605.4A Pending CN103998916A (zh) 2011-12-28 2012-10-25 微芯片和微芯片型细微粒测量装置

Country Status (5)

Country Link
US (1) US20140370586A1 (enExample)
EP (1) EP2798331A1 (enExample)
JP (1) JP2013137267A (enExample)
CN (1) CN103998916A (enExample)
WO (1) WO2013099078A1 (enExample)

Cited By (5)

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CN107923836A (zh) * 2015-06-17 2018-04-17 贝克顿·迪金森公司 具有可移除散射杆的光学检测器散射帽组件及其使用方法
CN108700500A (zh) * 2015-12-30 2018-10-23 生物辐射实验室股份有限公司 用于颗粒的光学检测系统
CN108700730A (zh) * 2016-02-23 2018-10-23 株式会社岛津制作所 显微分析装置
WO2021218463A1 (zh) * 2020-04-26 2021-11-04 青岛海信宽带多媒体技术有限公司 一种光模块
CN114632557A (zh) * 2020-12-16 2022-06-17 合肥京东方光电科技有限公司 一种微流控芯片的对置基板及微流控芯片

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US20170227447A1 (en) * 2014-08-06 2017-08-10 Beckman Coulter, Inc. Evaluation of multi-peak events using a flow cytometer
US10060847B2 (en) 2015-12-30 2018-08-28 Bio-Rad Laboratories, Inc. Detection and signal processing system for particle assays
EP3574305A1 (en) * 2017-01-30 2019-12-04 Miltenyi Biotec B.V. & Co. KG Printed flow cell for photometer
EP3654018B1 (en) 2017-07-11 2023-06-21 Hamamatsu Photonics K.K. Sample observation device and sample observation method
EP3655759A1 (en) * 2017-07-19 2020-05-27 Fundació Institut de Ciències Fotòniques A hand-held microfluidic detection device
US11204310B2 (en) * 2017-09-21 2021-12-21 Bit Group France Optical flow cytometer for epi fluorescence measurement
JP7165346B2 (ja) * 2018-08-10 2022-11-04 東ソー株式会社 粒子検出装置
JP7439438B2 (ja) * 2019-09-30 2024-02-28 ソニーグループ株式会社 生体粒子分析用マイクロチップ、生体粒子分析装置、微小粒子分析用マイクロチップ、及び微小粒子分析装置

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CN101581728A (zh) * 2008-05-13 2009-11-18 索尼株式会社 微芯片和用于微芯片的通道结构
CN101893569A (zh) * 2009-05-21 2010-11-24 索尼公司 微粒测量装置
US20110294139A1 (en) * 2009-02-06 2011-12-01 On-Chip Biotechnologies Co., Ltd. Disposable chip-type flow cell and flow cytometer using same

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JP5487638B2 (ja) 2009-02-17 2014-05-07 ソニー株式会社 微小粒子分取のための装置及びマイクロチップ
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US20060073599A1 (en) * 1995-06-16 2006-04-06 University Of Washington Microfabricated diffusion-based chemical sensor
JP2005091093A (ja) * 2003-09-16 2005-04-07 Olympus Corp 吸光度測定用マイクロチップ
CN101581728A (zh) * 2008-05-13 2009-11-18 索尼株式会社 微芯片和用于微芯片的通道结构
US20110294139A1 (en) * 2009-02-06 2011-12-01 On-Chip Biotechnologies Co., Ltd. Disposable chip-type flow cell and flow cytometer using same
CN101893569A (zh) * 2009-05-21 2010-11-24 索尼公司 微粒测量装置

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107923836A (zh) * 2015-06-17 2018-04-17 贝克顿·迪金森公司 具有可移除散射杆的光学检测器散射帽组件及其使用方法
CN108700500A (zh) * 2015-12-30 2018-10-23 生物辐射实验室股份有限公司 用于颗粒的光学检测系统
CN108700500B (zh) * 2015-12-30 2021-10-29 生物辐射实验室股份有限公司 用于颗粒的光学检测系统
CN108700730A (zh) * 2016-02-23 2018-10-23 株式会社岛津制作所 显微分析装置
CN108700730B (zh) * 2016-02-23 2020-12-29 株式会社岛津制作所 显微分析装置
WO2021218463A1 (zh) * 2020-04-26 2021-11-04 青岛海信宽带多媒体技术有限公司 一种光模块
CN114632557A (zh) * 2020-12-16 2022-06-17 合肥京东方光电科技有限公司 一种微流控芯片的对置基板及微流控芯片
CN114632557B (zh) * 2020-12-16 2024-05-28 合肥京东方光电科技有限公司 一种微流控芯片的对置基板及微流控芯片

Also Published As

Publication number Publication date
US20140370586A1 (en) 2014-12-18
EP2798331A1 (en) 2014-11-05
JP2013137267A (ja) 2013-07-11
WO2013099078A1 (en) 2013-07-04

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Application publication date: 20140820