JP2013126987A5 - - Google Patents
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- Publication number
- JP2013126987A5 JP2013126987A5 JP2013007593A JP2013007593A JP2013126987A5 JP 2013126987 A5 JP2013126987 A5 JP 2013126987A5 JP 2013007593 A JP2013007593 A JP 2013007593A JP 2013007593 A JP2013007593 A JP 2013007593A JP 2013126987 A5 JP2013126987 A5 JP 2013126987A5
- Authority
- JP
- Japan
- Prior art keywords
- binding
- tsh receptor
- molecule
- tsh
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000003911 Thyrotropin Receptors Human genes 0.000 claims 79
- 108090000253 Thyrotropin Receptors Proteins 0.000 claims 79
- 239000012634 fragment Substances 0.000 claims 47
- 230000003993 interaction Effects 0.000 claims 13
- 201000010099 disease Diseases 0.000 claims 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 12
- 239000003446 ligand Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 230000002401 inhibitory effect Effects 0.000 claims 9
- 238000012544 monitoring process Methods 0.000 claims 7
- 210000001124 body fluid Anatomy 0.000 claims 6
- 239000010839 body fluid Substances 0.000 claims 5
- 208000023275 Autoimmune disease Diseases 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 238000012216 screening Methods 0.000 claims 4
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- 230000003491 cAMP production Effects 0.000 claims 1
- 238000000099 in vitro assay Methods 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 230000000638 stimulation Effects 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0227964.4A GB0227964D0 (en) | 2002-11-29 | 2002-11-29 | Binding partners for the thyrotropin receptor and uses thereof |
| GB0227964.4 | 2002-11-29 | ||
| GB0302140.9 | 2003-01-29 | ||
| GBGB0302140.9A GB0302140D0 (en) | 2002-11-29 | 2003-01-29 | Binding partners for the thyrotropin receptor and uses thereof |
| GB0315147.9 | 2003-06-27 | ||
| GB0315147A GB0315147D0 (en) | 2002-11-29 | 2003-06-27 | Binding partners for the thyrotropin receptor and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004570698A Division JP5314234B2 (ja) | 2002-11-29 | 2003-11-28 | チロトロピン受容体の結合対象及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013126987A JP2013126987A (ja) | 2013-06-27 |
| JP2013126987A5 true JP2013126987A5 (enExample) | 2013-12-05 |
| JP5722927B2 JP5722927B2 (ja) | 2015-05-27 |
Family
ID=9948838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013007593A Expired - Lifetime JP5722927B2 (ja) | 2002-11-29 | 2013-01-18 | チロトロピン受容体の結合対象及びその使用 |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP5722927B2 (enExample) |
| AT (1) | ATE525086T1 (enExample) |
| ES (2) | ES2371244T3 (enExample) |
| GB (2) | GB0227964D0 (enExample) |
| HU (1) | HUE034370T2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5304939B1 (ja) * | 2012-05-31 | 2013-10-02 | 大日本印刷株式会社 | 光学積層体、偏光板、偏光板の製造方法、画像表示装置、画像表示装置の製造方法及び画像表示装置の視認性改善方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9909661D0 (en) * | 1998-06-06 | 1999-06-23 | Rsr Ltd | Assays for TSH receptor autoantibodies |
| US8110664B2 (en) * | 2002-11-29 | 2012-02-07 | Rsr Limited | Binding partners for the thyrotropin receptor and uses thereof |
-
2002
- 2002-11-29 GB GBGB0227964.4A patent/GB0227964D0/en not_active Ceased
-
2003
- 2003-01-29 GB GBGB0302140.9A patent/GB0302140D0/en not_active Ceased
- 2003-11-28 ES ES03778537T patent/ES2371244T3/es not_active Expired - Lifetime
- 2003-11-28 ES ES10184462.9T patent/ES2624241T3/es not_active Expired - Lifetime
- 2003-11-28 HU HUE10184462A patent/HUE034370T2/en unknown
- 2003-11-28 AT AT03778537T patent/ATE525086T1/de active
-
2013
- 2013-01-18 JP JP2013007593A patent/JP5722927B2/ja not_active Expired - Lifetime
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