JP2016528236A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016528236A5 JP2016528236A5 JP2016533450A JP2016533450A JP2016528236A5 JP 2016528236 A5 JP2016528236 A5 JP 2016528236A5 JP 2016533450 A JP2016533450 A JP 2016533450A JP 2016533450 A JP2016533450 A JP 2016533450A JP 2016528236 A5 JP2016528236 A5 JP 2016528236A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- monoclonal antibody
- human
- timp2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361863073P | 2013-08-07 | 2013-08-07 | |
| US61/863,073 | 2013-08-07 | ||
| PCT/US2014/050195 WO2015021308A1 (en) | 2013-08-07 | 2014-08-07 | Assays for timp2 having improved performance in biological samples |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016528236A JP2016528236A (ja) | 2016-09-15 |
| JP2016528236A5 true JP2016528236A5 (enExample) | 2017-08-10 |
Family
ID=52461941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533450A Pending JP2016528236A (ja) | 2013-08-07 | 2014-08-07 | 生物学的試料において改善された性能を有するｔｉｍｐ２のためのアッセイ |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9879091B2 (enExample) |
| EP (2) | EP3030582A4 (enExample) |
| JP (1) | JP2016528236A (enExample) |
| KR (1) | KR20160039682A (enExample) |
| CN (1) | CN105531291A (enExample) |
| AU (1) | AU2014305883A1 (enExample) |
| BR (1) | BR112016002685A2 (enExample) |
| CA (1) | CA2920521A1 (enExample) |
| EA (1) | EA201690185A1 (enExample) |
| HK (1) | HK1222180A1 (enExample) |
| MX (1) | MX2016001573A (enExample) |
| WO (1) | WO2015021308A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104391115B (zh) | 2008-10-21 | 2017-04-19 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| KR20120123056A (ko) | 2009-12-20 | 2012-11-07 | 아스튜트 메디컬 인코포레이티드 | 신손상 및 신부전을 진단 및 예측하는 방법 및 조성물 |
| EP2585827A4 (en) | 2010-06-23 | 2013-12-04 | Astute Medical Inc | METHOD AND COMPOSITIONS FOR DIAGNOSIS AND FORECASTING kidney injury and kidney insufficiency |
| WO2013086359A1 (en) | 2011-12-08 | 2013-06-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| ES2681955T3 (es) | 2013-01-17 | 2018-09-17 | Astute Medical, Inc. | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
| CN105917229B (zh) | 2013-12-03 | 2019-04-26 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| WO2016164854A1 (en) | 2015-04-09 | 2016-10-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP3397973A4 (en) * | 2015-12-30 | 2019-06-05 | Bio-Rad Laboratories, Inc. | DROP ANALYSIS SYSTEM WITH AUTOMATIC CALIBRATION |
| AU2017277305A1 (en) | 2016-06-06 | 2018-12-20 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| WO2018006049A1 (en) * | 2016-06-30 | 2018-01-04 | The Research Foundation For The State University Of New York | Compositions and methods for modifying activity of extracellular mmp-2 |
| ES2908239T3 (es) * | 2016-10-28 | 2022-04-28 | Astute Medical Inc | Uso de anticuerpos contra timp-2 para la mejora de la función renal |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2018187453A1 (en) * | 2017-04-05 | 2018-10-11 | Astute Medical, Inc. | Assays for timp2 having improved performance in biological samples |
| WO2019227055A1 (en) | 2018-05-24 | 2019-11-28 | Renibus Therapeutics, Inc. | Methods of treating patients at risk for renal injury and renal failure |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US459004A (en) | 1891-09-08 | Box for steaming cops | ||
| DE3029579C2 (de) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5698671A (en) * | 1989-03-21 | 1997-12-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Metalloproteinase peptides |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| ES2087997T3 (es) | 1990-01-12 | 1996-08-01 | Cell Genesys Inc | Generacion de anticuerpos xenogenicos. |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| US5166051A (en) | 1990-08-08 | 1992-11-24 | Genesis Labs, Inc. | Membranes, membrane overlays for exclusion of erythrocytes, and method for immunoassay of whole blood analytes |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| JPH05504841A (ja) | 1990-09-14 | 1993-07-22 | バイオサイト・ダイアグノスティックス・インコーポレイテッド | リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途 |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| WO1992018868A1 (en) | 1991-04-10 | 1992-10-29 | Biosite Diagnostics Incorporated | Crosstalk inhibitors and their uses |
| ATE195808T1 (de) | 1991-04-12 | 2000-09-15 | Biosite Diagnostics Inc | Neue konjugate und testverfahren für die gleichzeitige bestimmung von multiplen liganden |
| US6797492B2 (en) | 1991-05-17 | 2004-09-28 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| EP0940468A1 (en) | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Humanized antibody variable domain |
| US6019944A (en) | 1992-05-21 | 2000-02-01 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6562596B1 (en) * | 1993-10-06 | 2003-05-13 | Amgen Inc. | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods |
| EP0822830B1 (en) | 1995-04-27 | 2008-04-02 | Amgen Fremont Inc. | Human anti-IL-8 antibodies, derived from immunized xenomice |
| CA2219486A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6391265B1 (en) | 1996-08-26 | 2002-05-21 | Biosite Diagnostics, Inc. | Devices incorporating filters for filtering fluid samples |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| EP2305027B1 (en) | 1996-12-03 | 2014-07-02 | Amgen Fremont Inc. | Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom |
| US6045899A (en) | 1996-12-12 | 2000-04-04 | Usf Filtration & Separations Group, Inc. | Highly assymetric, hydrophilic, microfiltration membranes having large pore diameters |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| DE69837544T2 (de) * | 1997-07-16 | 2007-12-20 | Charm Sciences, Inc., Lawrence | Testgerät und methode zur entdeckung von analyten in proben |
| JP2002507725A (ja) * | 1998-03-16 | 2002-03-12 | クイデル コーポレイション | イムノアッセイデバイスおよび方法 |
| US7214542B2 (en) * | 2003-01-30 | 2007-05-08 | Michael Hutchinson | Method of processing assay test results |
| WO2004096832A2 (en) | 2003-04-29 | 2004-11-11 | Children's Medical Center Corporation | Novel antiangiogenic peptides |
| CN1833169A (zh) * | 2003-08-11 | 2006-09-13 | 协和梅迪克斯株式会社 | 测量对象物测量器具、测量装置和测量方法 |
| CA2574417C (en) * | 2004-07-28 | 2010-09-28 | F. Hoffmann-La Roche Ag | Timp-2 as target/marker of beta cell failure |
| US7485468B2 (en) * | 2004-10-15 | 2009-02-03 | Galapagos Bv | Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases |
| WO2007048100A2 (en) * | 2005-10-18 | 2007-04-26 | The Government Of The United States, As Represented By The Secretary Of Health & Human Services | Angio-inhibitory peptides derived from human timp-2 |
| CN104391115B (zh) | 2008-10-21 | 2017-04-19 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| US8900881B2 (en) * | 2008-12-30 | 2014-12-02 | Jin Po Lee | Quantitative analyte assay device and method |
| KR20120123056A (ko) | 2009-12-20 | 2012-11-07 | 아스튜트 메디컬 인코포레이티드 | 신손상 및 신부전을 진단 및 예측하는 방법 및 조성물 |
| US9903865B2 (en) * | 2010-03-31 | 2018-02-27 | Sekisui Medical Co., Ltd. | Assay, immunochromatographic test strip, and assay reagent kit for measuring an analyte, using a hematocrit correction |
-
2014
- 2014-08-07 CA CA2920521A patent/CA2920521A1/en not_active Abandoned
- 2014-08-07 AU AU2014305883A patent/AU2014305883A1/en not_active Abandoned
- 2014-08-07 CN CN201480048192.1A patent/CN105531291A/zh active Pending
- 2014-08-07 JP JP2016533450A patent/JP2016528236A/ja active Pending
- 2014-08-07 US US14/910,661 patent/US9879091B2/en active Active
- 2014-08-07 WO PCT/US2014/050195 patent/WO2015021308A1/en not_active Ceased
- 2014-08-07 HK HK16110255.1A patent/HK1222180A1/zh unknown
- 2014-08-07 KR KR1020167005705A patent/KR20160039682A/ko not_active Withdrawn
- 2014-08-07 EP EP14834090.4A patent/EP3030582A4/en not_active Withdrawn
- 2014-08-07 EA EA201690185A patent/EA201690185A1/ru unknown
- 2014-08-07 BR BR112016002685A patent/BR112016002685A2/pt not_active Application Discontinuation
- 2014-08-07 EP EP19183111.4A patent/EP3617234A1/en not_active Withdrawn
- 2014-08-07 MX MX2016001573A patent/MX2016001573A/es unknown
-
2018
- 2018-01-29 US US15/882,936 patent/US10457744B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016528236A5 (enExample) | ||
| Wu et al. | Portable GMR handheld platform for the detection of influenza A virus | |
| Lum et al. | Rapid detection of avian influenza H5N1 virus using impedance measurement of immuno-reaction coupled with RBC amplification | |
| Justino et al. | Immunosensors in clinical laboratory diagnostics | |
| Salmain et al. | Piezoelectric immunosensor for direct and rapid detection of staphylococcal enterotoxin A (SEA) at the ng level | |
| JP2019530875A5 (enExample) | ||
| US10908158B2 (en) | Immunoassay methods utilizing trapping conjugate | |
| NZ613646A (en) | Elisa for vegf | |
| WO2013132347A3 (en) | Improved elisa immunoassay for calprotectin | |
| MX2009004460A (es) | Inmunoensayo de analitos en muestras que contienen anticuerpos anti-analito endogenos. | |
| Xia et al. | Design of elution strategy for simultaneous detection of chloramphenicol and gentamicin in complex samples using surface plasmon resonance | |
| JP2016511417A5 (enExample) | ||
| JP2020516603A5 (enExample) | ||
| CN103649755B (zh) | Tsh免疫测定以及用于在存在内源性污染物的情况下以有限洗涤形式进行tsh免疫测定的方法 | |
| KR20120017884A (ko) | 자성입자의 항체고정화 방법 및 이를 이용해 제조되는 진단스트립, 진단키트 | |
| CN104597232A (zh) | 一种可扩展检测范围的捕获抗体竞争夹心免疫检测方法及生物传感器 | |
| Bong et al. | Competitive immunoassay of SARS-CoV-2 using pig sera-derived anti-SARS-CoV-2 antibodies | |
| JP2013174612A5 (enExample) | ||
| Kim et al. | Dual synergistic response for the electrochemical detection of H1N1 virus and viral proteins using high affinity peptide receptors | |
| Real-Fernández et al. | Label-free method for anti-glucopeptide antibody detection in Multiple Sclerosis | |
| JP2015529211A5 (enExample) | ||
| Shao et al. | Cerebrospinal fluid leak detection with a carbon nanotube-based field-effect transistor biosensing platform | |
| Manfredi et al. | Piezoelectric immunosensor based on antibody recognition of immobilized open-tissue transglutaminase: An innovative perspective on diagnostic devices for celiac disease | |
| JP2018533021A5 (enExample) | ||
| Hecht et al. | Label-acquired magnetorotation as a signal transduction method for protein detection: aptamer-based detection of thrombin |