MX2016001573A - Ensayos para timp2 con mejor rendimiento en muestras biológicas. - Google Patents
Ensayos para timp2 con mejor rendimiento en muestras biológicas.Info
- Publication number
- MX2016001573A MX2016001573A MX2016001573A MX2016001573A MX2016001573A MX 2016001573 A MX2016001573 A MX 2016001573A MX 2016001573 A MX2016001573 A MX 2016001573A MX 2016001573 A MX2016001573 A MX 2016001573A MX 2016001573 A MX2016001573 A MX 2016001573A
- Authority
- MX
- Mexico
- Prior art keywords
- timp2
- assays
- biological samples
- improved performance
- immunoassays
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/38—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361863073P | 2013-08-07 | 2013-08-07 | |
| PCT/US2014/050195 WO2015021308A1 (en) | 2013-08-07 | 2014-08-07 | Assays for timp2 having improved performance in biological samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016001573A true MX2016001573A (es) | 2016-09-07 |
Family
ID=52461941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016001573A MX2016001573A (es) | 2013-08-07 | 2014-08-07 | Ensayos para timp2 con mejor rendimiento en muestras biológicas. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9879091B2 (enExample) |
| EP (2) | EP3617234A1 (enExample) |
| JP (1) | JP2016528236A (enExample) |
| KR (1) | KR20160039682A (enExample) |
| CN (1) | CN105531291A (enExample) |
| AU (1) | AU2014305883A1 (enExample) |
| BR (1) | BR112016002685A2 (enExample) |
| CA (1) | CA2920521A1 (enExample) |
| EA (1) | EA201690185A1 (enExample) |
| HK (1) | HK1222180A1 (enExample) |
| MX (1) | MX2016001573A (enExample) |
| WO (1) | WO2015021308A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106370857A (zh) | 2008-10-21 | 2017-02-01 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| CN102725636B (zh) | 2009-12-20 | 2015-04-01 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2013086359A1 (en) | 2011-12-08 | 2013-06-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP6681195B2 (ja) | 2013-01-17 | 2020-04-15 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| CN110007084B (zh) | 2013-12-03 | 2022-11-18 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| US11243202B2 (en) | 2015-04-09 | 2022-02-08 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2017117490A1 (en) * | 2015-12-30 | 2017-07-06 | Bio-Rad Laboratories, Inc. | Droplet assay system with automatic calibration |
| CN109844526A (zh) | 2016-06-06 | 2019-06-04 | 机敏医药股份有限公司 | 使用胰岛素样生长因子结合蛋白7和金属蛋白酶2的组织抑制剂管理急性肾损伤 |
| WO2018006049A1 (en) * | 2016-06-30 | 2018-01-04 | The Research Foundation For The State University Of New York | Compositions and methods for modifying activity of extracellular mmp-2 |
| CN110352073A (zh) * | 2016-10-28 | 2019-10-18 | 机敏医药股份有限公司 | 针对timp-2的抗体用于改善肾功能的用途 |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP3606554A4 (en) * | 2017-04-05 | 2020-12-09 | Astute Medical, Inc. | ASSAYS FOR TIMP2 WITH IMPROVED EFFICIENCY IN BIOLOGICAL SAMPLES |
| CA3101470A1 (en) | 2018-05-24 | 2019-11-28 | Renibus Therapeutics, Inc. | Methods of treating patients at risk for renal injury and renal failure |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US459004A (en) | 1891-09-08 | Box for steaming cops | ||
| DE3029579C2 (de) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5698671A (en) * | 1989-03-21 | 1997-12-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Metalloproteinase peptides |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| ES2284161T3 (es) | 1990-01-12 | 2007-11-01 | Amgen Fremont Inc. | Generacion de anticuerpos xenogenicos. |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| US5166051A (en) | 1990-08-08 | 1992-11-24 | Genesis Labs, Inc. | Membranes, membrane overlays for exclusion of erythrocytes, and method for immunoassay of whole blood analytes |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| AU8507191A (en) | 1990-08-29 | 1992-03-30 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| CA2072758A1 (en) | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| ATE177841T1 (de) | 1991-04-10 | 1999-04-15 | Biosite Diagnostics Inc | ''crosstalk''- oder übersprech-inhibitoren und ihre verwendung |
| CA2107899A1 (en) | 1991-04-10 | 1992-10-11 | Gunars Edwin Valkirs | Novel conjugates and assays for simultaneous detection of multiple ligands |
| US6797492B2 (en) | 1991-05-17 | 2004-09-28 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
| ATE255131T1 (de) | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5885527A (en) | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6562596B1 (en) * | 1993-10-06 | 2003-05-13 | Amgen Inc. | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods |
| EP0822830B1 (en) | 1995-04-27 | 2008-04-02 | Amgen Fremont Inc. | Human anti-IL-8 antibodies, derived from immunized xenomice |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6391265B1 (en) | 1996-08-26 | 2002-05-21 | Biosite Diagnostics, Inc. | Devices incorporating filters for filtering fluid samples |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| ATE549918T1 (de) | 1996-12-03 | 2012-04-15 | Amgen Fremont Inc | Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden |
| US6045899A (en) | 1996-12-12 | 2000-04-04 | Usf Filtration & Separations Group, Inc. | Highly assymetric, hydrophilic, microfiltration membranes having large pore diameters |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| EP0998676B1 (en) * | 1997-07-16 | 2007-04-11 | Charm Sciences Inc. | A test device and method for detecting the presence of a residue analyte in a sample |
| WO1999047930A1 (en) * | 1998-03-16 | 1999-09-23 | Quidel Corporation | Immunoassay device and method |
| US7214542B2 (en) * | 2003-01-30 | 2007-05-08 | Michael Hutchinson | Method of processing assay test results |
| WO2004096832A2 (en) | 2003-04-29 | 2004-11-11 | Children's Medical Center Corporation | Novel antiangiogenic peptides |
| EP1662257A4 (en) * | 2003-08-11 | 2007-12-12 | Kyowa Medex Co Ltd | TOOL FOR MEASURING MEASURING OBJECT, MEASURING DEVICE AND MEASURING METHOD |
| US20100009462A1 (en) | 2004-07-28 | 2010-01-14 | Andreas Christ | Timp-2 as target/marker of beta cell failure |
| US7485468B2 (en) * | 2004-10-15 | 2009-02-03 | Galapagos Bv | Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases |
| WO2007048102A2 (en) * | 2005-10-18 | 2007-04-26 | The Government Of The United States, As Represented By The Secretary Of Health And Human Services | Angio-inhibitory peptides derived from human timp-2 |
| CN106370857A (zh) | 2008-10-21 | 2017-02-01 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| US8900881B2 (en) * | 2008-12-30 | 2014-12-02 | Jin Po Lee | Quantitative analyte assay device and method |
| CN102725636B (zh) | 2009-12-20 | 2015-04-01 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| KR101858765B1 (ko) * | 2010-03-31 | 2018-05-16 | 세키스이 메디칼 가부시키가이샤 | 면역 크로마토그래피를 이용한 측정 방법, 면역 크로마토그래피용 테스트 스트립 및 면역 크로마토그래피용 측정 시약 키트 |
-
2014
- 2014-08-07 WO PCT/US2014/050195 patent/WO2015021308A1/en not_active Ceased
- 2014-08-07 EP EP19183111.4A patent/EP3617234A1/en not_active Withdrawn
- 2014-08-07 JP JP2016533450A patent/JP2016528236A/ja active Pending
- 2014-08-07 KR KR1020167005705A patent/KR20160039682A/ko not_active Withdrawn
- 2014-08-07 MX MX2016001573A patent/MX2016001573A/es unknown
- 2014-08-07 EP EP14834090.4A patent/EP3030582A4/en not_active Withdrawn
- 2014-08-07 CA CA2920521A patent/CA2920521A1/en not_active Abandoned
- 2014-08-07 CN CN201480048192.1A patent/CN105531291A/zh active Pending
- 2014-08-07 US US14/910,661 patent/US9879091B2/en active Active
- 2014-08-07 AU AU2014305883A patent/AU2014305883A1/en not_active Abandoned
- 2014-08-07 BR BR112016002685A patent/BR112016002685A2/pt not_active Application Discontinuation
- 2014-08-07 EA EA201690185A patent/EA201690185A1/ru unknown
- 2014-08-07 HK HK16110255.1A patent/HK1222180A1/zh unknown
-
2018
- 2018-01-29 US US15/882,936 patent/US10457744B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3030582A1 (en) | 2016-06-15 |
| BR112016002685A2 (pt) | 2018-01-30 |
| HK1222180A1 (zh) | 2017-06-23 |
| US20180162953A1 (en) | 2018-06-14 |
| CN105531291A (zh) | 2016-04-27 |
| EA201690185A1 (ru) | 2016-07-29 |
| CA2920521A1 (en) | 2015-02-12 |
| EP3030582A4 (en) | 2017-05-17 |
| US9879091B2 (en) | 2018-01-30 |
| EP3617234A1 (en) | 2020-03-04 |
| US10457744B2 (en) | 2019-10-29 |
| WO2015021308A1 (en) | 2015-02-12 |
| AU2014305883A1 (en) | 2016-02-25 |
| KR20160039682A (ko) | 2016-04-11 |
| US20160297893A1 (en) | 2016-10-13 |
| JP2016528236A (ja) | 2016-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112016002685A2 (pt) | ensaios para timp2 que apresentam melhor desempenho em amostras biológicas | |
| EA201690731A1 (ru) | Анализ igfbp7, имеющий улучшенную характеристику в биологических образцах | |
| MX2020009021A (es) | Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco. | |
| MX2015012823A (es) | Ensayo de combinacion de antigeno-anticuerpo del virus de la hepatitis c (vhc) y metodos y composiciones para usarlo. | |
| HK1254633A1 (zh) | 用於分析样品,尤其是血液,的装置和系统以及使用它的方法 | |
| AU2018200278B2 (en) | Antibodies to aripiprazole and use thereof | |
| MX377956B (es) | Sistemas y métodos para maximización de uso de muestras. | |
| BR112016019836A2 (pt) | método para analisar uma amostra de um sujeito, dispositivo de diagnóstico para utilização no diagnóstico da endometriose, kit, uso de um biomarcador, e, método para aumentar uma resposta de anticorpos em um sujeito | |
| EP3933406A3 (en) | Antibodies to risperidone and use thereof | |
| WO2014015194A3 (en) | Methods for detecting and measuring aggregation | |
| BR112015007672A2 (pt) | anticorpos anti-pd-l1 monoclonais humanos e métodos de uso | |
| HK1207421A1 (en) | Methods and systems for detecting an analyte or classifying a sample | |
| MY172290A (en) | Immunochromatography devices, methods, and, kits | |
| EA201792289A1 (ru) | Способы обнаружения агглютинации и композиции для их осуществления | |
| WO2014031668A3 (en) | Antibodies to quetiapine and use thereof | |
| WO2015191546A3 (en) | Adp-ribose detection reagents | |
| WO2014031662A3 (en) | Antibodies to olanzapine and use thereof | |
| WO2015061299A3 (en) | Point-of-care immunosensing device for multi-biomarker detection | |
| BR112014031958A2 (pt) | bag3 como marcador de tecido e soro bioquímico | |
| MX2019000591A (es) | Tira mejorada de ensayo de analisis de orina de bajo volumen de muestra, kits analiticos y metodos de uso relacionados con la misma. | |
| WO2014173546A3 (en) | Platelet allo-antigen typing and platelet antibody tests | |
| WO2014151290A3 (en) | Assay for predictive biomarkers | |
| GB201119585D0 (en) | Assay | |
| WO2016071698A3 (en) | A test device and method of using a test device | |
| GB2521885A8 (en) | An immunoassay detection device |