GB0302140D0 - Binding partners for the thyrotropin receptor and uses thereof - Google Patents

Binding partners for the thyrotropin receptor and uses thereof

Info

Publication number
GB0302140D0
GB0302140D0 GBGB0302140.9A GB0302140A GB0302140D0 GB 0302140 D0 GB0302140 D0 GB 0302140D0 GB 0302140 A GB0302140 A GB 0302140A GB 0302140 D0 GB0302140 D0 GB 0302140D0
Authority
GB
United Kingdom
Prior art keywords
tsh receptor
binding partners
thyrotropin receptor
binding partner
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0302140.9A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RSR Ltd
Original Assignee
RSR Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RSR Ltd filed Critical RSR Ltd
Publication of GB0302140D0 publication Critical patent/GB0302140D0/en
Priority to GB0315147A priority Critical patent/GB0315147D0/en
Priority to EP10184462.9A priority patent/EP2383296B1/en
Priority to PCT/GB2003/005171 priority patent/WO2004050708A2/en
Priority to AT03778537T priority patent/ATE525086T1/en
Priority to CN2003801041189A priority patent/CN1717418B/en
Priority to HUE10184462A priority patent/HUE034370T2/en
Priority to AU2003285540A priority patent/AU2003285540A1/en
Priority to JP2004570698A priority patent/JP5314234B2/en
Priority to DK10184462.9T priority patent/DK2383296T3/en
Priority to ES10184462.9T priority patent/ES2624241T3/en
Priority to US10/537,280 priority patent/US8110664B2/en
Priority to EP03778537A priority patent/EP1565493B1/en
Priority to US13/339,111 priority patent/US8753637B2/en
Priority to US13/339,596 priority patent/US8900823B2/en
Priority to JP2013007593A priority patent/JP5722927B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Mycology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROBLEM TO BE SOLVED: To provide a binding partner for the TSH receptor capable of interacting with the TSH receptor in a manner comparable to the interaction of TSH receptor autoantibodies with the TSH receptor.SOLUTION: There is provided the binding partner for the TSH receptor, which includes, or is derived from, a human monoclonal or recombinant antibody, or fragments thereof, and is reactive with the TSH receptor. There are also provided uses thereof, methods of diagnosis and therapy employing the same, and anti-idiotypic antibodies thereto.
GBGB0302140.9A 2002-11-29 2003-01-29 Binding partners for the thyrotropin receptor and uses thereof Ceased GB0302140D0 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
GB0315147A GB0315147D0 (en) 2002-11-29 2003-06-27 Binding partners for the thyrotropin receptor and uses thereof
EP03778537A EP1565493B1 (en) 2002-11-29 2003-11-28 Antibody for the thyrotropin receptor and uses thereof
AU2003285540A AU2003285540A1 (en) 2002-11-29 2003-11-28 Antibody for the thyrotropin receptor and uses thereof
DK10184462.9T DK2383296T3 (en) 2002-11-29 2003-11-28 Antibody of the thyrotropin receptor and its applications
AT03778537T ATE525086T1 (en) 2002-11-29 2003-11-28 ANTIBODIES TO THYROTROPINE RECEPTOR AND THEIR USES
CN2003801041189A CN1717418B (en) 2002-11-29 2003-11-28 Antibody for the thyrotropin receptor and uses thereof
HUE10184462A HUE034370T2 (en) 2002-11-29 2003-11-28 Antibody for the thyrotropin receptor and uses thereof
EP10184462.9A EP2383296B1 (en) 2002-11-29 2003-11-28 Antibody for the thyrotropin receptor and uses thereof
JP2004570698A JP5314234B2 (en) 2002-11-29 2003-11-28 Binding targets of thyrotropin receptor and use thereof
PCT/GB2003/005171 WO2004050708A2 (en) 2002-11-29 2003-11-28 Antibody for the thyrotropin receptor and uses thereof
ES10184462.9T ES2624241T3 (en) 2002-11-29 2003-11-28 Thyrotropin receptor antibody and its uses
US10/537,280 US8110664B2 (en) 2002-11-29 2003-11-28 Binding partners for the thyrotropin receptor and uses thereof
US13/339,111 US8753637B2 (en) 2002-11-29 2011-12-28 Binding partners for the thyrotropin receptor and uses thereof
US13/339,596 US8900823B2 (en) 2002-11-29 2011-12-29 Binding partners for the thyrotropin receptor and uses thereof
JP2013007593A JP5722927B2 (en) 2002-11-29 2013-01-18 Binding targets of thyrotropin receptor and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0227964.4A GB0227964D0 (en) 2002-11-29 2002-11-29 Binding partners for the thyrotropin receptor and uses thereof

Publications (1)

Publication Number Publication Date
GB0302140D0 true GB0302140D0 (en) 2003-03-05

Family

ID=9948838

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0227964.4A Ceased GB0227964D0 (en) 2002-11-29 2002-11-29 Binding partners for the thyrotropin receptor and uses thereof
GBGB0302140.9A Ceased GB0302140D0 (en) 2002-11-29 2003-01-29 Binding partners for the thyrotropin receptor and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB0227964.4A Ceased GB0227964D0 (en) 2002-11-29 2002-11-29 Binding partners for the thyrotropin receptor and uses thereof

Country Status (5)

Country Link
JP (1) JP5722927B2 (en)
AT (1) ATE525086T1 (en)
ES (2) ES2624241T3 (en)
GB (2) GB0227964D0 (en)
HU (1) HUE034370T2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5304939B1 (en) * 2012-05-31 2013-10-02 大日本印刷株式会社 Optical laminate, polarizing plate, method for manufacturing polarizing plate, image display device, method for manufacturing image display device, and method for improving visibility of image display device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9909661D0 (en) * 1998-06-06 1999-06-23 Rsr Ltd Assays for TSH receptor autoantibodies
EP1565493B1 (en) * 2002-11-29 2011-09-21 Rsr Limited Antibody for the thyrotropin receptor and uses thereof

Also Published As

Publication number Publication date
ES2624241T3 (en) 2017-07-13
HUE034370T2 (en) 2018-02-28
GB0227964D0 (en) 2003-01-08
ATE525086T1 (en) 2011-10-15
JP5722927B2 (en) 2015-05-27
JP2013126987A (en) 2013-06-27
ES2371244T3 (en) 2011-12-28

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)