JP2013063093A5 - - Google Patents
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- Publication number
- JP2013063093A5 JP2013063093A5 JP2013004389A JP2013004389A JP2013063093A5 JP 2013063093 A5 JP2013063093 A5 JP 2013063093A5 JP 2013004389 A JP2013004389 A JP 2013004389A JP 2013004389 A JP2013004389 A JP 2013004389A JP 2013063093 A5 JP2013063093 A5 JP 2013063093A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- hypercharged
- variant
- protein variant
- physiological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000018102 proteins Nutrition 0.000 claims 50
- 108090000623 proteins and genes Proteins 0.000 claims 50
- 102000004169 proteins and genes Human genes 0.000 claims 50
- 238000000034 method Methods 0.000 claims 12
- 235000001014 amino acid Nutrition 0.000 claims 4
- 125000000539 amino acid group Chemical group 0.000 claims 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 4
- 238000006467 substitution reaction Methods 0.000 claims 3
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 108010090804 Streptavidin Proteins 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 108020001507 fusion proteins Proteins 0.000 claims 2
- 102000037865 fusion proteins Human genes 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 102000003839 Human Proteins Human genes 0.000 claims 1
- 108090000144 Human Proteins Proteins 0.000 claims 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- 150000001413 amino acids Chemical group 0.000 claims 1
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 1
- 235000003704 aspartic acid Nutrition 0.000 claims 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 claims 1
- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81036406P | 2006-06-02 | 2006-06-02 | |
| US60/810,364 | 2006-06-02 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009513478A Division JP5396270B2 (ja) | 2006-06-02 | 2007-06-01 | タンパク質表面のリモデリング |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014232389A Division JP2015033392A (ja) | 2006-06-02 | 2014-11-17 | タンパク質表面のリモデリング |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013063093A JP2013063093A (ja) | 2013-04-11 |
| JP2013063093A5 true JP2013063093A5 (enExample) | 2014-05-29 |
Family
ID=40892102
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009513478A Expired - Fee Related JP5396270B2 (ja) | 2006-06-02 | 2007-06-01 | タンパク質表面のリモデリング |
| JP2013004389A Pending JP2013063093A (ja) | 2006-06-02 | 2013-01-15 | タンパク質表面のリモデリング |
| JP2014232389A Pending JP2015033392A (ja) | 2006-06-02 | 2014-11-17 | タンパク質表面のリモデリング |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009513478A Expired - Fee Related JP5396270B2 (ja) | 2006-06-02 | 2007-06-01 | タンパク質表面のリモデリング |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014232389A Pending JP2015033392A (ja) | 2006-06-02 | 2014-11-17 | タンパク質表面のリモデリング |
Country Status (2)
| Country | Link |
|---|---|
| JP (3) | JP5396270B2 (enExample) |
| CN (1) | CN101490548A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104678092B (zh) * | 2015-01-28 | 2017-06-06 | 山东大学 | 高正电荷荧光蛋白在糖胺聚糖分析检测中的应用 |
| CN109752557B (zh) * | 2017-11-06 | 2021-06-08 | 清华大学 | 检测生物分子间相互作用及其调控因子的成套试剂与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK316989D0 (da) * | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
| DE60140457D1 (de) * | 2000-09-01 | 2009-12-24 | Blood Res Center | Veränderte, in gewünschter konformation stabilisierte polypeptide und verfahren zu deren herstellung |
| US7311701B2 (en) * | 2003-06-10 | 2007-12-25 | Cierra, Inc. | Methods and apparatus for non-invasively treating atrial fibrillation using high intensity focused ultrasound |
| DE10342670A1 (de) * | 2003-09-16 | 2005-04-21 | Bayer Healthcare Ag | Isoliertes Photoprotein mtClytin, sowie dessen Verwendung |
| US20070281332A1 (en) * | 2004-02-13 | 2007-12-06 | Allan Svendsen | Protease Variants |
-
2007
- 2007-06-01 CN CNA2007800271393A patent/CN101490548A/zh active Pending
- 2007-06-01 JP JP2009513478A patent/JP5396270B2/ja not_active Expired - Fee Related
-
2013
- 2013-01-15 JP JP2013004389A patent/JP2013063093A/ja active Pending
-
2014
- 2014-11-17 JP JP2014232389A patent/JP2015033392A/ja active Pending
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