JP2013006854A5 - - Google Patents
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- Publication number
- JP2013006854A5 JP2013006854A5 JP2012191753A JP2012191753A JP2013006854A5 JP 2013006854 A5 JP2013006854 A5 JP 2013006854A5 JP 2012191753 A JP2012191753 A JP 2012191753A JP 2012191753 A JP2012191753 A JP 2012191753A JP 2013006854 A5 JP2013006854 A5 JP 2013006854A5
- Authority
- JP
- Japan
- Prior art keywords
- halogen atom
- alkyl group
- thio
- hydrogen atom
- glucitol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012191753A JP5660094B2 (ja) | 2009-04-16 | 2012-08-31 | 併用医薬 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009100210 | 2009-04-16 | ||
| JP2009100210 | 2009-04-16 | ||
| JP2012191753A JP5660094B2 (ja) | 2009-04-16 | 2012-08-31 | 併用医薬 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011540651A Division JP5077786B2 (ja) | 2009-04-16 | 2010-04-16 | 併用医薬 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014245257A Division JP5910711B2 (ja) | 2009-04-16 | 2014-12-03 | 併用医薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013006854A JP2013006854A (ja) | 2013-01-10 |
| JP2013006854A5 true JP2013006854A5 (enExample) | 2013-05-30 |
| JP5660094B2 JP5660094B2 (ja) | 2015-01-28 |
Family
ID=42982643
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011540651A Active JP5077786B2 (ja) | 2009-04-16 | 2010-04-16 | 併用医薬 |
| JP2012191753A Expired - Fee Related JP5660094B2 (ja) | 2009-04-16 | 2012-08-31 | 併用医薬 |
| JP2014245257A Active JP5910711B2 (ja) | 2009-04-16 | 2014-12-03 | 併用医薬 |
| JP2015253932A Active JP6066144B2 (ja) | 2009-04-16 | 2015-12-25 | 併用医薬 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011540651A Active JP5077786B2 (ja) | 2009-04-16 | 2010-04-16 | 併用医薬 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014245257A Active JP5910711B2 (ja) | 2009-04-16 | 2014-12-03 | 併用医薬 |
| JP2015253932A Active JP6066144B2 (ja) | 2009-04-16 | 2015-12-25 | 併用医薬 |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US20120040898A1 (enExample) |
| EP (3) | EP2601949B1 (enExample) |
| JP (4) | JP5077786B2 (enExample) |
| KR (2) | KR20120016051A (enExample) |
| CN (7) | CN105434430A (enExample) |
| AR (1) | AR076317A1 (enExample) |
| AU (1) | AU2010237748B2 (enExample) |
| BR (1) | BRPI1012539A2 (enExample) |
| CA (1) | CA2755392A1 (enExample) |
| CY (2) | CY1114703T1 (enExample) |
| DK (2) | DK2419097T3 (enExample) |
| ES (2) | ES2431300T3 (enExample) |
| HK (6) | HK1217302A1 (enExample) |
| HR (2) | HRP20131120T1 (enExample) |
| ME (2) | ME02015B (enExample) |
| MX (1) | MX2011010901A (enExample) |
| MY (3) | MY182720A (enExample) |
| NZ (4) | NZ595314A (enExample) |
| PH (3) | PH12015500235A1 (enExample) |
| PL (2) | PL2601949T3 (enExample) |
| PT (2) | PT2419097E (enExample) |
| RS (2) | RS53761B1 (enExample) |
| RU (2) | RU2532330C2 (enExample) |
| SG (6) | SG175154A1 (enExample) |
| SI (2) | SI2601949T1 (enExample) |
| SM (1) | SMT201500015B (enExample) |
| TW (3) | TW201500043A (enExample) |
| UA (2) | UA105216C2 (enExample) |
| WO (1) | WO2010119990A1 (enExample) |
| ZA (1) | ZA201106727B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7772191B2 (en) | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
| EP4684831A3 (en) | 2009-02-13 | 2026-03-11 | Boehringer Ingelheim International GmbH | Sglt2 inhibitor for improving glycemic control |
| BR112012007085B8 (pt) | 2009-09-30 | 2021-05-25 | Boehringer Ingelheim Int | processos para a preparação de derivados de benzil-benzeno substituídos com glicopiranosila |
| UY32919A (es) | 2009-10-02 | 2011-04-29 | Boehringer Ingelheim Int | Composición farmacéutica, forma de dosificación farmacéutica, procedimiento para su preparación, mé todos para su tratamiento y sus usos |
| US20120283169A1 (en) * | 2010-11-08 | 2012-11-08 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| TR201101809A1 (tr) * | 2010-12-21 | 2012-07-23 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Vildagliptin ve glimepirid kombinasyonları. |
| US9192617B2 (en) | 2012-03-20 | 2015-11-24 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| SG11201406987UA (en) | 2012-05-17 | 2014-12-30 | Transtech Pharma Llc | Glucokinase activator compositions for the treatment of diabetes |
| HK1208621A1 (en) * | 2012-08-30 | 2016-03-11 | 大正制药株式会社 | Combination of sglt2 inhibitor and anti-hypertension drug |
| CA2812519A1 (en) | 2013-04-05 | 2014-10-05 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| US11813275B2 (en) | 2013-04-05 | 2023-11-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| US20140303097A1 (en) | 2013-04-05 | 2014-10-09 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| TR201901110T4 (tr) | 2013-04-05 | 2019-02-21 | Boehringer Ingelheim Int | Empagliflozinin terapötik kullanımları. |
| HK1215378A1 (zh) | 2013-04-18 | 2016-08-26 | 勃林格殷格翰国际有限公司 | 药物组合物、治疗方法及其用途 |
| TW201636015A (zh) * | 2013-07-05 | 2016-10-16 | 卡地拉保健有限公司 | 協同性組成物 |
| KR102060728B1 (ko) * | 2015-02-27 | 2019-12-30 | 재단법인 아산사회복지재단 | Dpp-4 억제제를 포함하는 판막 석회화의 예방 또는 치료용 조성물 |
| CN105963280B (zh) * | 2016-06-30 | 2018-11-06 | 合肥华方医药科技有限公司 | 一种伏格列波糖口腔速溶膜及其制备方法 |
| EP3528800A1 (en) | 2016-10-19 | 2019-08-28 | Boehringer Ingelheim International GmbH | Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof |
| AU2017357589B2 (en) | 2016-11-10 | 2023-05-11 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| US11439689B2 (en) * | 2016-11-14 | 2022-09-13 | Kaohsiung Medical University | Method for detecting whether glucose metabolism is abnormal, and prevention and treatment therefor |
| AU2019254371A1 (en) | 2018-04-17 | 2020-10-08 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| KR20190137343A (ko) | 2018-06-01 | 2019-12-11 | 김유찬 | 계량 인덕션 |
| KR20210020866A (ko) | 2018-06-12 | 2021-02-24 | 브이티브이 테라퓨틱스 엘엘씨 | 인슐린 또는 인슐린 유사체와 조합된 글루코키나제 활성제의 치료적 용도 |
| CN112955215B (zh) | 2018-10-29 | 2024-05-17 | 勃林格殷格翰国际有限公司 | 吡啶基磺酰胺衍生物、药物组合物及其用途 |
| CN112955214B (zh) | 2018-10-29 | 2024-05-07 | 勃林格殷格翰国际有限公司 | 吡啶基磺酰胺衍生物、药物组合物及其用途 |
| WO2021167840A1 (en) | 2020-02-18 | 2021-08-26 | Vtv Therapeutics Llc | Sulfoxide and sulfone glucokinase activators and methods of use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4432757A1 (de) | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
| JP2003520759A (ja) | 1999-08-31 | 2003-07-08 | アンドルックス ファーマスーティカルズ インコーポレーテッド | 単位核を有する徐放性錠剤 |
| US20030045553A1 (en) | 2001-04-04 | 2003-03-06 | Bussolari Jacqueline C. | Combination therapy comprising glucose reabsorption inhibitors and PPAR modulators |
| ATE318272T1 (de) * | 2001-04-11 | 2006-03-15 | Bristol Myers Squibb Co | Aminosäurekomplexe von c-arylglycosiden zur behandlung von diabetes und verfahren |
| TW200637839A (en) * | 2005-01-07 | 2006-11-01 | Taisho Pharmaceutical Co Ltd | 1-thio-d-glucitol derivatives |
| CA2655937A1 (en) * | 2006-06-29 | 2008-01-03 | Taisho Pharmaceutical Co., Ltd. | C-phenyl 1-thioglucitol compound |
| JP5194588B2 (ja) * | 2006-07-06 | 2013-05-08 | 大正製薬株式会社 | １−チオ−ｄ−グルシトール誘導体を有効成分として含有する糖尿病の予防又は治療剤 |
| EP2054426A1 (en) * | 2006-08-15 | 2009-05-06 | Boehringer Ingelheim International GmbH | Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as sglt inhibitors and process for their manufacture |
| EA018495B1 (ru) * | 2006-11-09 | 2013-08-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Комбинированное лечение ингибиторами sglt-2 (натрийзависимый сопереносчик глюкозы 2) и содержащими их фармацевтическими композициями |
| AU2007332476A1 (en) * | 2006-12-14 | 2008-06-19 | Taisho Pharmaceutical Co., Ltd. | 1-phenyl 1-thio-D-glucitol derivative |
| CL2008002425A1 (es) | 2007-08-16 | 2009-09-11 | Boehringer Ingelheim Int | Composición farmacéutica que comprende un inhibidor de sglt2 y 1-(4-metil-quinazolin-2-il)metil-3metil-7-(-2-butin-1-il)-8-(3-(r)-amino-piperidin-1il)-xantina, un inhibidor de dpp iv y su uso para el tratamiento de la obesidad y de la diabetes tipo 1 y 2 y complicaciones de esta. |
| CL2008002427A1 (es) | 2007-08-16 | 2009-09-11 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2. |
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2010
- 2010-04-16 MY MYPI2015001283A patent/MY182720A/en unknown
- 2010-04-16 PL PL13157571T patent/PL2601949T3/pl unknown
- 2010-04-16 PT PT107645707T patent/PT2419097E/pt unknown
- 2010-04-16 SI SI201030784T patent/SI2601949T1/sl unknown
- 2010-04-16 AU AU2010237748A patent/AU2010237748B2/en not_active Ceased
- 2010-04-16 SG SG2011073848A patent/SG175154A1/en unknown
- 2010-04-16 EP EP13157571.4A patent/EP2601949B1/en active Active
- 2010-04-16 ME MEP-2015-6A patent/ME02015B/me unknown
- 2010-04-16 TW TW103133246A patent/TW201500043A/zh unknown
- 2010-04-16 TW TW099111992A patent/TW201103534A/zh unknown
- 2010-04-16 US US13/264,687 patent/US20120040898A1/en not_active Abandoned
- 2010-04-16 MY MYPI2011004937A patent/MY156679A/en unknown
- 2010-04-16 MX MX2011010901A patent/MX2011010901A/es active IP Right Grant
- 2010-04-16 HR HRP20131120AT patent/HRP20131120T1/hr unknown
- 2010-04-16 CN CN201510876753.3A patent/CN105434430A/zh active Pending
- 2010-04-16 CN CN201510876712.4A patent/CN105343871A/zh active Pending
- 2010-04-16 KR KR1020117023612A patent/KR20120016051A/ko not_active Ceased
- 2010-04-16 RS RS20150042A patent/RS53761B1/sr unknown
- 2010-04-16 NZ NZ595314A patent/NZ595314A/xx unknown
- 2010-04-16 PL PL10764570T patent/PL2419097T3/pl unknown
- 2010-04-16 SG SG2014014807A patent/SG2014014807A/en unknown
- 2010-04-16 CN CN201510876739.3A patent/CN105343880A/zh active Pending
- 2010-04-16 CN CN2010800169522A patent/CN102395364A/zh active Pending
- 2010-04-16 DK DK10764570.7T patent/DK2419097T3/da active
- 2010-04-16 KR KR1020157009538A patent/KR20150046382A/ko not_active Ceased
- 2010-04-16 NZ NZ606888A patent/NZ606888A/en not_active IP Right Cessation
- 2010-04-16 PT PT131575714T patent/PT2601949E/pt unknown
- 2010-04-16 CN CN201510876678.0A patent/CN105477639A/zh active Pending
- 2010-04-16 CA CA2755392A patent/CA2755392A1/en not_active Abandoned
- 2010-04-16 SI SI201030365T patent/SI2419097T1/sl unknown
- 2010-04-16 AR ARP100101273A patent/AR076317A1/es unknown
- 2010-04-16 ES ES10764570T patent/ES2431300T3/es active Active
- 2010-04-16 SG SG2014012462A patent/SG2014012462A/en unknown
- 2010-04-16 ME MEP-2013-137A patent/ME01555B/me unknown
- 2010-04-16 CN CN201510876708.8A patent/CN105343060A/zh active Pending
- 2010-04-16 MY MYPI2015001281A patent/MY183793A/en unknown
- 2010-04-16 UA UAA201113444A patent/UA105216C2/ru unknown
- 2010-04-16 UA UAA201314870A patent/UA111742C2/uk unknown
- 2010-04-16 SG SG2014012405A patent/SG2014012405A/en unknown
- 2010-04-16 RU RU2011146335/15A patent/RU2532330C2/ru not_active IP Right Cessation
- 2010-04-16 EP EP10764570.7A patent/EP2419097B1/en active Active
- 2010-04-16 BR BRPI1012539A patent/BRPI1012539A2/pt not_active IP Right Cessation
- 2010-04-16 SG SG2014015093A patent/SG2014015093A/en unknown
- 2010-04-16 WO PCT/JP2010/057196 patent/WO2010119990A1/en not_active Ceased
- 2010-04-16 RS RS20130508A patent/RS53056B/sr unknown
- 2010-04-16 JP JP2011540651A patent/JP5077786B2/ja active Active
- 2010-04-16 ES ES13157571.4T patent/ES2523408T3/es active Active
- 2010-04-16 EP EP14183168.5A patent/EP2829271A3/en not_active Withdrawn
- 2010-04-16 DK DK13157571.4T patent/DK2601949T3/da active
- 2010-04-16 NZ NZ710575A patent/NZ710575A/en not_active IP Right Cessation
- 2010-04-16 NZ NZ623838A patent/NZ623838A/en not_active IP Right Cessation
- 2010-04-16 SG SG2014012553A patent/SG2014012553A/en unknown
- 2010-04-16 CN CN201510876636.7A patent/CN105343059A/zh active Pending
- 2010-04-16 TW TW105105937A patent/TW201622720A/zh unknown
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2011
- 2011-09-14 ZA ZA2011/06727A patent/ZA201106727B/en unknown
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2012
- 2012-08-31 JP JP2012191753A patent/JP5660094B2/ja not_active Expired - Fee Related
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2013
- 2013-12-05 CY CY20131101103T patent/CY1114703T1/el unknown
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2014
- 2014-05-26 RU RU2014121260/15A patent/RU2014121260A/ru not_active Application Discontinuation
- 2014-11-05 HR HRP20141080AT patent/HRP20141080T1/hr unknown
- 2014-12-03 JP JP2014245257A patent/JP5910711B2/ja active Active
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2015
- 2015-01-16 CY CY20151100045T patent/CY1115907T1/el unknown
- 2015-01-19 SM SM201500015T patent/SMT201500015B/xx unknown
- 2015-02-03 PH PH12015500235A patent/PH12015500235A1/en unknown
- 2015-12-25 JP JP2015253932A patent/JP6066144B2/ja active Active
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2016
- 2016-05-11 HK HK16105353.2A patent/HK1217302A1/zh unknown
- 2016-05-11 HK HK16105348.0A patent/HK1217301A1/zh unknown
- 2016-05-12 HK HK16105415.8A patent/HK1217434A1/zh unknown
- 2016-05-12 HK HK16105417.6A patent/HK1217435A1/zh unknown
- 2016-06-16 HK HK16106920.4A patent/HK1218871A1/zh unknown
- 2016-06-17 HK HK16106970.3A patent/HK1218881A1/zh unknown
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2019
- 2019-04-30 PH PH12019500959A patent/PH12019500959B1/en unknown
- 2019-04-30 PH PH12019500961A patent/PH12019500961B1/en unknown