JP2012533631A5 - - Google Patents
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- Publication number
- JP2012533631A5 JP2012533631A5 JP2012521703A JP2012521703A JP2012533631A5 JP 2012533631 A5 JP2012533631 A5 JP 2012533631A5 JP 2012521703 A JP2012521703 A JP 2012521703A JP 2012521703 A JP2012521703 A JP 2012521703A JP 2012533631 A5 JP2012533631 A5 JP 2012533631A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- amino acid
- acid sequence
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22694509P | 2009-07-20 | 2009-07-20 | |
| US61/226,945 | 2009-07-20 | ||
| PCT/US2010/042423 WO2011011315A1 (en) | 2009-07-20 | 2010-07-19 | POLYPEPTIDES SELECTIVE FOR AV β3 INTEGRIN CONJUGATED WITH A VARIANT OF HUMAN SERUM ALBUMIN (HSA) AND PHARMACEUTICAL USES THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012533631A JP2012533631A (ja) | 2012-12-27 |
| JP2012533631A5 true JP2012533631A5 (enExample) | 2013-09-05 |
Family
ID=43465728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521703A Pending JP2012533631A (ja) | 2009-07-20 | 2010-07-19 | ヒト血清アルブミン（ＨＳＡ）の変異体と接合したαｖβ３インテグリンに対して選択的なポリペプチドおよびその医薬上の使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20110015130A1 (enExample) |
| EP (1) | EP2456454A4 (enExample) |
| JP (1) | JP2012533631A (enExample) |
| KR (1) | KR20120097481A (enExample) |
| CN (1) | CN102470156A (enExample) |
| AR (1) | AR077764A1 (enExample) |
| AU (1) | AU2010276453A1 (enExample) |
| CA (1) | CA2768360A1 (enExample) |
| IL (1) | IL217424A0 (enExample) |
| MX (1) | MX2012000895A (enExample) |
| NZ (1) | NZ597580A (enExample) |
| RU (1) | RU2547592C2 (enExample) |
| TW (1) | TWI557224B (enExample) |
| WO (1) | WO2011011315A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG172789A1 (en) | 2009-02-11 | 2011-08-29 | Novozymes Biopharma Dk As | Albumin variants and conjugates |
| AU2010311332B2 (en) | 2009-10-30 | 2015-04-23 | Albumedix Ltd. | Albumin variants |
| US8357652B2 (en) * | 2009-11-20 | 2013-01-22 | Academia Sinica | Anti-tumor fibrillar human serum albumin methods and compositions |
| KR20120130752A (ko) * | 2009-12-23 | 2012-12-03 | 내셔널 타이완 유니버시티 | 혈관신생-관련된 안질환의 치료를 위한 조성물 및 방법 |
| WO2011103076A1 (en) | 2010-02-16 | 2011-08-25 | Medlmmune, Llc | Hsa-related compositions and methods of use |
| KR20130070576A (ko) | 2010-04-09 | 2013-06-27 | 노보자임스 바이오파마 디케이 에이/에스 | 알부민 유도체 및 변이체 |
| US9045564B2 (en) | 2011-02-15 | 2015-06-02 | Medimmune, Llc | HSA-related compositions and methods of use |
| WO2012150319A1 (en) | 2011-05-05 | 2012-11-08 | Novozymes Biopharma Dk A/S | Albumin variants |
| HK1200842A1 (en) | 2011-11-18 | 2015-08-14 | Albumedix Ltd | Proteins with improved half-life and other properties |
| EP3330283A3 (en) | 2012-03-16 | 2018-07-11 | Albumedix A/S | Albumin variants |
| CA2890766A1 (en) | 2012-11-08 | 2014-05-15 | Novozymes Biopharma Dk A/S | Albumin variants |
| CA2958906C (en) * | 2014-08-22 | 2021-05-04 | National Cheng Kung University | Disintegrin variants and pharmaceutical uses thereof |
| MX382540B (es) * | 2015-06-28 | 2025-03-13 | Allgenesis Biotherapeutics Inc | Proteinas de fusion para inhibir la angiogenesis |
| EA034582B1 (ru) * | 2015-08-07 | 2020-02-21 | АЭлЭкс ОНКОЛОДЖИ ИНК. | Конструкции варианта sirp-альфа и их применение |
| RU2740672C2 (ru) | 2015-08-07 | 2021-01-19 | ЭйЭлЭкс Онколоджи Инк. | Конструкции, имеющие sirp-альфа домен или его вариант |
| BR112018003179A2 (pt) | 2015-08-20 | 2018-09-25 | Albumedix As | conjugados e variantes de albumina |
| US10336812B2 (en) * | 2016-05-10 | 2019-07-02 | Janssen Biotech, Inc. | GDF15 fusion proteins and uses thereof |
| MY205905A (en) | 2018-10-22 | 2024-11-20 | Janssen Pharmaceutica Nv | Glucagon like peptide 1 (glp1)-growth differentiation factor 15 (gdf15) fusion proteins and uses thereof |
| CA3141130A1 (en) | 2019-05-31 | 2020-12-03 | ALX Oncology Inc. | Methods of treating cancer with sirp alpha fc fusion in combination with an immune checkpoint inhibitor |
| WO2021108693A1 (en) | 2019-11-27 | 2021-06-03 | ALX Oncology Inc. | Combination therapies for treating cancer |
| EP4310187A4 (en) * | 2021-03-16 | 2025-03-19 | KM Biologics Co., Ltd. | MODIFIED HUMAN SERUM ALBUMIN THIOREDOX INFUSION BODY |
| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
| WO2026022392A1 (en) * | 2024-07-26 | 2026-01-29 | Ospedale San Raffaele S.R.L. | Peptide and conjugates thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) * | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) * | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| EP0206448B1 (en) * | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
| US4791192A (en) * | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| WO1990015072A1 (en) * | 1989-06-07 | 1990-12-13 | Genentech, Inc. | Platelet aggregation inhibitors and related molecules |
| US5525708A (en) * | 1994-03-28 | 1996-06-11 | Cytomed, Inc. | Covalent dimer of kit ligand |
| WO2003042354A2 (en) * | 2001-09-04 | 2003-05-22 | Aventis Pharmaceuticals Inc. | Abrogen polypeptides, nucleic acids encoding them and methods for using them to inhibit angiogenesis |
| CA2465891C (en) * | 2001-11-05 | 2012-05-15 | Board Of Regents, The University Of Texas System | Recombinant antibodies for the detection and neutralization of anthrax toxin |
| KR101271635B1 (ko) * | 2001-12-21 | 2013-06-12 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 알부민 융합 단백질 |
| JP2005529166A (ja) * | 2002-06-07 | 2005-09-29 | ウィスコンシン アルムニ リサーチ ファウンデーション | ペプチドカップリングのための試薬の化学合成 |
| CA2560525A1 (en) * | 2004-03-18 | 2005-09-29 | The University Court Of The University Of Glasgow | Immunosuppressive cytokine |
| WO2008056961A1 (en) * | 2006-11-10 | 2008-05-15 | Boryung Pharmaceutical Co., Ltd | A novel fusion protein, cell lines expressing the same and preparation method thereof |
| US8183201B2 (en) * | 2006-12-26 | 2012-05-22 | National Cheng Kung University | Methods of treating αvβ3 integrin-associated diseases by administering polypeptides selective for αvβ3 integrin |
| US7943728B2 (en) * | 2006-12-26 | 2011-05-17 | National Cheng Kung University | Disintegrin variants and their use in treating osteoporosis-induced bone loss and angiogenesis-related diseases |
| KR20120130752A (ko) * | 2009-12-23 | 2012-12-03 | 내셔널 타이완 유니버시티 | 혈관신생-관련된 안질환의 치료를 위한 조성물 및 방법 |
-
2010
- 2010-07-19 EP EP10802718A patent/EP2456454A4/en not_active Withdrawn
- 2010-07-19 JP JP2012521703A patent/JP2012533631A/ja active Pending
- 2010-07-19 TW TW099123673A patent/TWI557224B/zh active
- 2010-07-19 AR ARP100102628A patent/AR077764A1/es unknown
- 2010-07-19 MX MX2012000895A patent/MX2012000895A/es not_active Application Discontinuation
- 2010-07-19 KR KR1020127004303A patent/KR20120097481A/ko not_active Withdrawn
- 2010-07-19 RU RU2012105915/10A patent/RU2547592C2/ru not_active IP Right Cessation
- 2010-07-19 CN CN2010800332967A patent/CN102470156A/zh active Pending
- 2010-07-19 WO PCT/US2010/042423 patent/WO2011011315A1/en not_active Ceased
- 2010-07-19 AU AU2010276453A patent/AU2010276453A1/en not_active Abandoned
- 2010-07-19 US US12/838,926 patent/US20110015130A1/en not_active Abandoned
- 2010-07-19 CA CA2768360A patent/CA2768360A1/en not_active Abandoned
- 2010-07-19 NZ NZ597580A patent/NZ597580A/xx not_active IP Right Cessation
-
2012
- 2012-01-08 IL IL217424A patent/IL217424A0/en unknown
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