JP2012532125A5 - - Google Patents
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- Publication number
- JP2012532125A5 JP2012532125A5 JP2012518512A JP2012518512A JP2012532125A5 JP 2012532125 A5 JP2012532125 A5 JP 2012532125A5 JP 2012518512 A JP2012518512 A JP 2012518512A JP 2012518512 A JP2012518512 A JP 2012518512A JP 2012532125 A5 JP2012532125 A5 JP 2012532125A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- disease
- dementia
- compound
- alzheimer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22165709P | 2009-06-30 | 2009-06-30 | |
| US61/221,657 | 2009-06-30 | ||
| PCT/SE2010/050747 WO2011002405A1 (en) | 2009-06-30 | 2010-06-29 | 2-carboxamide-7-piperazinyl-benzofuran derivatives 774 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532125A JP2012532125A (ja) | 2012-12-13 |
| JP2012532125A5 true JP2012532125A5 (https=) | 2013-08-01 |
| JP5767211B2 JP5767211B2 (ja) | 2015-08-19 |
Family
ID=43381415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012518512A Expired - Fee Related JP5767211B2 (ja) | 2009-06-30 | 2010-06-29 | ２−カルボキサミド−７−ピペラジニル−ベンゾフラン誘導体７７４ |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8367676B2 (https=) |
| EP (1) | EP2448934B1 (https=) |
| JP (1) | JP5767211B2 (https=) |
| KR (1) | KR20120110000A (https=) |
| CN (1) | CN102482264B (https=) |
| AR (1) | AR077301A1 (https=) |
| AU (1) | AU2010266753B2 (https=) |
| BR (1) | BRPI1014222A2 (https=) |
| CA (1) | CA2765475A1 (https=) |
| MX (1) | MX2011013449A (https=) |
| RU (1) | RU2011152516A (https=) |
| TW (1) | TW201103922A (https=) |
| UY (1) | UY32744A (https=) |
| WO (1) | WO2011002405A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8367676B2 (en) | 2009-06-30 | 2013-02-05 | Astrazeneca Ab | 2-carboxamide-7-piperazinyl-benzofuran derivatives 774 |
| CN103380129B (zh) | 2010-12-20 | 2016-04-20 | 阿克图拉姆生命科学股份公司 | 2-甲酰胺-4-哌嗪基-苯并呋喃衍生物 |
| CN102993186B (zh) * | 2012-12-20 | 2015-11-18 | 北京海步国际医药科技发展有限公司 | 一种新型的哌嗪衍生物 |
| CN105339371A (zh) * | 2013-03-07 | 2016-02-17 | 葛兰素史密斯克莱有限责任公司 | 作为沉默调节蛋白调节剂的噻吩并[3,2-d]嘧啶-6-甲酰胺和类似物 |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| EP3917911A1 (en) * | 2019-01-31 | 2021-12-08 | Kyorin Pharmaceutical Co., Ltd. | 15-pgdh inhibitors |
| WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
| KR20230035036A (ko) * | 2020-06-05 | 2023-03-10 | 모나쉬 유니버시티 | 이중 키나제-브로모도메인 억제제 |
| US20230391758A1 (en) * | 2020-09-18 | 2023-12-07 | Merck Sharp & Dohme Llc | Modified benzofuran-carboxamides as glucosylceramide synthase inhibitors |
| CN117430574B (zh) * | 2023-12-20 | 2024-03-22 | 潍坊医学院 | 一种苯并呋喃衍生物及其制备方法、用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9125900D0 (en) * | 1991-12-05 | 1992-02-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
| DK148392D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
| KR100545329B1 (ko) | 1997-07-25 | 2006-01-24 | 하. 룬트벡 아크티에 셀스카브 | 인돌 및 2,3-디히드로인돌 유도체, 그들의 제조방법 및 사용 |
| AR022303A1 (es) | 1999-01-22 | 2002-09-04 | Lundbeck & Co As H | Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion |
| ES2268113T3 (es) | 2001-06-15 | 2007-03-16 | F. Hoffmann-La Roche Ag | Derivados de 4-piperazinilindol con afinidad al receptor 5-ht6. |
| MXPA04012439A (es) | 2002-06-10 | 2005-04-19 | Bayer Healthcare Ag | Amidas de acidos 2-heteroarilcarboxilicos. |
| GB0227240D0 (en) | 2002-11-21 | 2002-12-31 | Glaxo Group Ltd | Compounds |
| DE10259244A1 (de) * | 2002-12-17 | 2004-07-01 | Merck Patent Gmbh | N-(Indolethyl-)cycloamin-Verbindungen |
| DE10326939A1 (de) * | 2003-06-16 | 2005-01-05 | Merck Patent Gmbh | Indol-Derivate |
| DE10326940A1 (de) | 2003-06-16 | 2005-01-05 | Merck Patent Gmbh | Indol-Derivate |
| WO2005077885A1 (en) | 2004-02-06 | 2005-08-25 | Yale University | Ruthenium-catalyzed hydroamination of olefins |
| WO2006062481A1 (en) | 2004-12-09 | 2006-06-15 | Biovitrum Ab | New benzofuran derivatives and their use in the treatment of obesity, type ii diabetes and cns disorders . |
| WO2007053093A1 (en) | 2005-11-04 | 2007-05-10 | Astrazeneca Ab | Chroman compounds as 5 ht1b antagonists |
| AR059356A1 (es) | 2006-02-14 | 2008-03-26 | Astrazeneca Ab | Nuevos radioligandos |
| JP2010504367A (ja) | 2006-09-26 | 2010-02-12 | グラクソ グループ リミテッド | 性機能障害、認知障害、精神病性障害、不安、鬱病などを処置するための５ｈｔ１ａ受容体モジュレーターとしての５−｛２−［４−（２−メチル−５−キノリニル）−ｌ−ピペリジニル］エチル｝キノリノン誘導体 |
| CA2668959A1 (en) | 2006-11-09 | 2008-05-15 | F. Hoffmann-La Roche Ag | Indole and benzofuran 2-carboxamide derivatives |
| US8367676B2 (en) | 2009-06-30 | 2013-02-05 | Astrazeneca Ab | 2-carboxamide-7-piperazinyl-benzofuran derivatives 774 |
-
2010
- 2010-06-28 US US12/824,567 patent/US8367676B2/en not_active Expired - Fee Related
- 2010-06-29 KR KR1020117031427A patent/KR20120110000A/ko not_active Withdrawn
- 2010-06-29 AU AU2010266753A patent/AU2010266753B2/en not_active Ceased
- 2010-06-29 TW TW099121305A patent/TW201103922A/zh unknown
- 2010-06-29 CA CA2765475A patent/CA2765475A1/en not_active Abandoned
- 2010-06-29 EP EP10794458.9A patent/EP2448934B1/en active Active
- 2010-06-29 UY UY0001032744A patent/UY32744A/es unknown
- 2010-06-29 MX MX2011013449A patent/MX2011013449A/es active IP Right Grant
- 2010-06-29 RU RU2011152516/04A patent/RU2011152516A/ru not_active Application Discontinuation
- 2010-06-29 BR BRPI1014222A patent/BRPI1014222A2/pt not_active IP Right Cessation
- 2010-06-29 JP JP2012518512A patent/JP5767211B2/ja not_active Expired - Fee Related
- 2010-06-29 CN CN201080038560.6A patent/CN102482264B/zh not_active Expired - Fee Related
- 2010-06-29 WO PCT/SE2010/050747 patent/WO2011002405A1/en not_active Ceased
- 2010-06-30 AR ARP100102339A patent/AR077301A1/es unknown
-
2013
- 2013-02-04 US US13/758,098 patent/US8859534B2/en active Active
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