|
FR1311316A
(fr)
|
1961-04-12 |
1962-12-07 |
Science Union Et Compagnie Soc |
Nouveaux dérivés de la pipérazine et leurs préparations
|
|
NL127996C
(https=)
|
1963-11-19 |
|
|
|
|
US3485757A
(en)
|
1964-11-23 |
1969-12-23 |
Atomic Energy Commission |
Thermoelectric composition comprising doped bismuth telluride,silicon and boron
|
|
DE1595923A1
(de)
*
|
1965-02-20 |
1969-11-27 |
Merck Ag E |
1-Aralkyl-4-(thiazolyl-2)-piperazine und Verfahren zu ihrer Herstellung
|
|
GB1165283A
(en)
|
1967-01-17 |
1969-09-24 |
Science Union & Cie |
New Purine Derivatives and processes for prepararing them
|
|
US4600025A
(en)
|
1982-11-18 |
1986-07-15 |
Grigg Ronald E |
Smoking products comprising nicotine substitutes
|
|
EP0636130A1
(en)
|
1992-04-15 |
1995-02-01 |
Merck Sharp & Dohme Ltd. |
Azacyclic compounds
|
|
IL118768A
(en)
|
1995-07-12 |
2000-10-31 |
Akzo Nobel Nv |
Diphenylmethane piperidine derivatives pharmaceutical compositions containing them and a method for their preparation
|
|
TW504510B
(en)
|
1996-05-10 |
2002-10-01 |
Janssen Pharmaceutica Nv |
2,4-diaminopyrimidine derivatives
|
|
CA2282390A1
(en)
|
1997-04-17 |
1998-10-22 |
Yukio Fujisawa |
Thermogenic composition and benzazepine thermogenics
|
|
CN1191248C
(zh)
|
1997-10-24 |
2005-03-02 |
纽罗根公司 |
作为多巴胺d 受体亚型配体的1－(2－萘基)和1－(2－氮杂萘基)－4－(1－苯基甲基)哌嗪
|
|
CA2448080A1
(en)
*
|
2001-05-22 |
2002-11-28 |
Neurogen Corporation |
Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
|
|
US6982259B2
(en)
|
2002-04-30 |
2006-01-03 |
Schering Aktiengesellschaft |
N-heterocyclic derivatives as NOS inhibitors
|
|
MXPA04012440A
(es)
|
2002-06-12 |
2005-04-28 |
Abbott Lab |
Antagonistas de receptor de hormona concentradora de melanina.
|
|
AU2003243921B2
(en)
|
2002-06-27 |
2009-05-07 |
Novo Nordisk A/S |
Aryl carbonyl derivatives as therapeutic agents
|
|
DK1519939T5
(da)
|
2002-07-05 |
2011-01-24 |
Targacept Inc |
N-Aryl-diazaspirocykliske forbindelser og fremgangsmåder til fremstilling og anvendelse deraf
|
|
JP4712384B2
(ja)
|
2002-09-09 |
2011-06-29 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
Ｏｒｌ−１受容体介在障害の治療に有用なヒドロキシアルキル置換１，３，８−トリアザスピロ［４．５］デカン−４−オン誘導体
|
|
MXPA05011223A
(es)
|
2003-04-18 |
2006-01-26 |
Lilly Co Eli |
Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas 5-htif.
|
|
CA2526374A1
(en)
|
2003-05-21 |
2004-12-02 |
Banyu Pharmaceutical Co., Ltd. |
2-aminoquinoline derivatives
|
|
BRPI0506662B8
(pt)
|
2004-01-06 |
2021-05-25 |
Novo Nordisk As |
compostos ativadores de glucoquinase
|
|
WO2005110982A2
(en)
|
2004-04-07 |
2005-11-24 |
Neurogen Corporation |
Substituted 1-benzyl-4-substituted piperazine analogues
|
|
HU227119B1
(en)
|
2004-07-29 |
2010-07-28 |
Richter Gedeon Nyrt |
Indole and benzimidazole carboxylic acid amide derivatives and pharmaceutical compositions containing them
|
|
HUP0401522A2
(en)
|
2004-07-29 |
2006-04-28 |
Richter Gedeon Vegyeszet |
New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation
|
|
AU2006220187B2
(en)
|
2005-03-01 |
2012-11-08 |
Simon Fraser University |
Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof
|
|
EP1705177A1
(en)
*
|
2005-03-23 |
2006-09-27 |
Schering Aktiengesellschaft |
N-aryl-sulfoximine-substituted pyrimidines as CDK- and/or VEGF inhibitors, their production and use as pharmaceutical agents
|
|
TW200724140A
(en)
|
2005-05-27 |
2007-07-01 |
Eisai Co Ltd |
Hydantoin compounds
|
|
JP2009500377A
(ja)
|
2005-07-08 |
2009-01-08 |
ノボ・ノルデイスク・エー／エス |
ジシクロアルキルウレア型グルコキナーゼ活性化剤
|
|
WO2007008541A2
(en)
|
2005-07-08 |
2007-01-18 |
Kalypsys, Inc. |
Cellular cholesterol absorption modifiers
|
|
CA2646755A1
(en)
|
2006-03-31 |
2007-10-11 |
Astrazeneca Ab |
Bicyclic benzimidazole compounds and their use as metabotropic glutamate receptor potentiators
|
|
WO2007135398A1
(en)
|
2006-05-22 |
2007-11-29 |
Astrazeneca Ab |
Indole derivatives
|
|
US20080051387A1
(en)
|
2006-06-09 |
2008-02-28 |
Yuelian Xu |
Tetrahydropyrido[3,4-d]pyrimidines and related analogues
|
|
WO2008012623A1
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Benzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
EP2057171A4
(en)
|
2006-08-31 |
2010-04-21 |
Univ Fraser Simon |
SELECTIVE GLYCOSIDASE INHIBITORS AND APPLICATIONS THEREOF
|
|
US20100022517A1
(en)
|
2006-12-18 |
2010-01-28 |
Richards Lori A |
Ophthalmic formulation of rho kinase inhibitor compound
|
|
US8148369B2
(en)
|
2007-05-10 |
2012-04-03 |
Janssen Pharmaceutica Nv |
Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases
|
|
WO2009011904A1
(en)
|
2007-07-19 |
2009-01-22 |
Renovis, Inc. |
Compounds useful as faah modulators and uses thereof
|
|
US8404713B2
(en)
|
2007-10-26 |
2013-03-26 |
Janssen Pharmaceutica Nv |
Quinolinone derivatives as PARP inhibitors
|
|
WO2009086303A2
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
WO2009127943A1
(en)
|
2008-04-17 |
2009-10-22 |
Pfizer Inc. |
Ether benzylidene piperidine 5-membered aryl carboxamide compounds useful as faah inhibitors
|
|
CA2717087A1
(en)
|
2008-04-17 |
2009-10-22 |
Pfizer Inc. |
4-[3-(aryloxy)benzylidene]-3-methyl piperidine 5-membered aryl carboxamides
|
|
US7863291B2
(en)
|
2008-04-23 |
2011-01-04 |
Bristol-Myers Squibb Company |
Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands
|
|
JPWO2009154132A1
(ja)
|
2008-06-19 |
2011-12-01 |
Ｍｓｄ株式会社 |
スピロジアミン−ジアリールケトオキシム誘導体
|
|
JP2010065024A
(ja)
|
2008-08-14 |
2010-03-25 |
Ishihara Sangyo Kaisha Ltd |
トリアゾロピリミジン誘導体又はその塩を含有する有害生物防除剤
|
|
WO2010021381A1
(ja)
|
2008-08-22 |
2010-02-25 |
武田薬品工業株式会社 |
縮合複素環誘導体およびその用途
|
|
CA2735269C
(en)
|
2008-08-29 |
2018-10-16 |
Saint Mary's University |
Use of gluconacetobacter with reduced use of nitrogen fertilizer to improve beet crop production
|
|
CN102137841B
(zh)
|
2008-09-02 |
2014-05-14 |
日产化学工业株式会社 |
邻位取代卤代烷基磺酰苯胺衍生物及除草剂
|
|
TW201030007A
(en)
|
2009-02-06 |
2010-08-16 |
Gruenenthal Gmbh |
Substituted spiro-amides as b1r modulators
|
|
AU2010221417A1
(en)
|
2009-03-02 |
2011-09-22 |
Sirtris Pharmaceuticals, Inc. |
8-substituted quinolines and related analogs as sirtuin modulators
|
|
WO2010108115A1
(en)
|
2009-03-20 |
2010-09-23 |
Sanford-Burnham Medical Research Institute |
Allosteric jnk inhibitors
|
|
US20120010186A1
(en)
|
2009-03-23 |
2012-01-12 |
Merck Frosst Canada Ltd. |
Heterocyclic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
|
JP2010270034A
(ja)
|
2009-05-20 |
2010-12-02 |
Sumitomo Chemical Co Ltd |
アミド化合物並びにその植物病害防除用途
|
|
CA2765678A1
(en)
|
2009-06-22 |
2010-12-29 |
Christopher Blackburn |
Substituted hydroxamic acids and uses thereof
|
|
DE102009049679A1
(de)
|
2009-10-19 |
2011-04-21 |
Merck Patent Gmbh |
Pyrazolopyrimidinderivate
|
|
US9120781B2
(en)
|
2010-05-11 |
2015-09-01 |
Simon Fraser University |
Selective glycosidase inhibitors and uses thereof
|
|
US20130196971A1
(en)
|
2010-09-17 |
2013-08-01 |
Christopher Joseph Aquino |
Fatty acid synthase inhibitors
|
|
WO2012061972A1
(en)
|
2010-11-08 |
2012-05-18 |
Alectos Therapeutics Inc. |
Selective glycosidase inhibitors and uses thereof
|
|
AU2011328203B2
(en)
|
2010-11-08 |
2015-03-19 |
Janssen Pharmaceuticals, Inc. |
1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
|
|
US8933040B2
(en)
|
2010-11-08 |
2015-01-13 |
Craig A. Coburn |
Selective glycosidase inhibitors and uses thereof
|
|
DK2655388T3
(en)
|
2010-12-23 |
2016-09-19 |
Alectos Therapeutics Inc |
Selective glykosidaseinhibitorer and uses thereof
|
|
GB201103526D0
(en)
|
2011-03-02 |
2011-04-13 |
Summit Corp Plc |
Selective glycosidase inhibitors and uses thereof
|
|
JPWO2012124744A1
(ja)
|
2011-03-14 |
2014-07-24 |
大正製薬株式会社 |
含窒素縮合複素環化合物
|
|
AU2012298949B2
(en)
|
2011-08-25 |
2016-09-22 |
Merck Patent Gmbh |
Pyrano [3, 2 - D] [1, 3] thiazole as glycosidase inhibitors
|
|
US9221809B2
(en)
|
2011-10-31 |
2015-12-29 |
Merck Sharp & Dohme Corp. |
Aminopyrimidinones as interleukin receptor-associated kinase inhibitors
|
|
AR092031A1
(es)
|
2012-07-26 |
2015-03-18 |
Merck Sharp & Dohme |
Inhibidores del canal de potasio medular externo renal
|
|
WO2014023723A1
(en)
|
2012-08-08 |
2014-02-13 |
Novartis Ag |
Subtituted azines as pesticides
|
|
US9522883B2
(en)
|
2012-08-31 |
2016-12-20 |
Alectos Therapeutics Inc. |
Glycosidase inhibitors and uses thereof
|
|
PT2970272T
(pt)
|
2013-03-14 |
2019-06-05 |
Merck Patent Gmbh |
Inibidores de glicosidase
|
|
CN103435606A
(zh)
|
2013-08-22 |
2013-12-11 |
中国药科大学 |
CDK2与GSK3β双重抑制剂及用途
|
|
SI3077395T1
(en)
|
2013-12-05 |
2018-03-30 |
Pfizer Inc. |
Pyrrolo(2,3-d)pyrimidinyl, pyrrolo(2,3-b)pyrazinyl and pyrrolo(2,3-d)pyridinyl acrylamides
|
|
EP2913330A1
(en)
|
2014-02-27 |
2015-09-02 |
Laboratoire Biodim |
Condensed derivatives of imidazole useful as pharmaceuticals
|
|
HUE057317T2
(hu)
|
2014-04-23 |
2022-04-28 |
Dart Neuroscience Llc |
Helyettesített [1,2,4]triazolo[1,5-A]pirimidin-7-IL vegyületeket tartalmazó készítmények mint PDE2 inhibítorok
|
|
AR101197A1
(es)
*
|
2014-07-16 |
2016-11-30 |
Gruenenthal Gmbh |
Pirimidinas 2,5-sustituidas
|
|
EP3868752A1
(en)
*
|
2014-08-28 |
2021-08-25 |
Asceneuron SA |
Glycosidase inhibitors
|
|
EP3204374B1
(en)
*
|
2014-10-08 |
2019-04-03 |
UCB Biopharma SPRL |
Isoindoline derivatives
|
|
WO2016055479A1
(en)
*
|
2014-10-08 |
2016-04-14 |
Ucb Biopharma Sprl |
Tetrahydroisoquinoline derivatives
|
|
JP6787892B2
(ja)
*
|
2014-11-20 |
2020-11-18 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ |
Ｉｒａｋインヒビターとしてのヘテロアリール化合物及びその使用
|
|
AR103297A1
(es)
*
|
2014-12-30 |
2017-05-03 |
Forma Therapeutics Inc |
Pirrolo y pirazolopirimidinas como inhibidores de la proteasa 7 específica de ubiquitina
|
|
BR112017028318B1
(pt)
|
2015-07-02 |
2024-02-20 |
Janssen Sciences Ireland Uc |
Composto antibacteriano, seu uso, processo para sua preparação,produto que o contém, composição farmacêutica e combinação
|
|
ES2765738T3
(es)
|
2015-11-02 |
2020-06-10 |
Janssen Pharmaceutica Nv |
Compuesto de [1,2,4]triazolo[1,5-a]pirimidin-7-ilo
|
|
PT3371190T
(pt)
*
|
2015-11-06 |
2022-07-08 |
Incyte Corp |
Compostos heterocíclicos como inibidores de pi3k-gamma
|
|
WO2017087863A1
(en)
|
2015-11-20 |
2017-05-26 |
Abide Therapeutics, Inc. |
Pyrazole compounds and methods of making and using same
|
|
WO2017087858A1
(en)
|
2015-11-20 |
2017-05-26 |
Abide Therapeutics, Inc. |
Pyrazole compounds and methods of making and using same
|
|
EP3380471B8
(en)
|
2015-11-25 |
2022-01-19 |
Lieber Institute Inc. DBA Lieber Institute For Brain Development |
Tetrahydro-8h-pyrido[1,2-a]pyrazine-8-ones as comt inhibitors for the treatment of neurodegenerative disorders
|
|
EP3389658B1
(en)
|
2015-12-18 |
2020-11-25 |
Merck Sharp & Dohme Corp. |
Glycosidase inhibitors and uses thereof
|
|
US10344021B2
(en)
|
2016-02-25 |
2019-07-09 |
Asceneuron S A |
Process for the separation of enantiomers of piperazine derivatives
|
|
US11261183B2
(en)
|
2016-02-25 |
2022-03-01 |
Asceneuron Sa |
Sulfoximine glycosidase inhibitors
|
|
WO2018153508A2
(en)
|
2017-02-24 |
2018-08-30 |
Asceneuron S.A. |
Sulfoximine glycosidase inhibitors
|
|
SG11201807012QA
(en)
|
2016-02-25 |
2018-09-27 |
Asceneuron S A |
Acid addition salts of piperazine derivatives
|
|
CN108884078A
(zh)
|
2016-02-25 |
2018-11-23 |
阿森纽荣股份公司 |
糖苷酶抑制剂
|
|
EP3472129A4
(en)
|
2016-06-21 |
2019-12-04 |
X4 Pharmaceuticals, Inc. |
CXCR4 INHIBITORS AND USES THEREOF
|
|
US11186564B2
(en)
|
2016-08-04 |
2021-11-30 |
Sunovion Pharmaceuticals Inc. |
Dual NAV1.2/5HT2a inhibitors for treating CNS disorders
|
|
US20190359609A1
(en)
|
2016-12-16 |
2019-11-28 |
Janssen Pharmaceutica Nv |
Bicyclic oga inhibitor compounds
|
|
EP3555087A1
(en)
|
2016-12-16 |
2019-10-23 |
Janssen Pharmaceutica NV |
Monocyclic oga inhibitor compounds
|
|
TWI654978B
(zh)
|
2017-01-27 |
2019-04-01 |
美商美國禮來大藥廠 |
5－甲基－1,2,4－二唑－3－基化合物
|
|
AU2018216040A1
(en)
|
2017-02-06 |
2019-06-20 |
Janssen Pharmaceutica Nv |
OGA inhibitor compounds
|
|
WO2018154133A1
(en)
|
2017-02-27 |
2018-08-30 |
Janssen Pharmaceutica Nv |
[1,2,4]-triazolo [1,5-a]-pyrimidinyl derivatives substituted with piperidine, morpholine or piperazine as oga inhibitors
|
|
AR111693A1
(es)
|
2017-05-25 |
2019-08-07 |
Lilly Co Eli |
Compuestos de 5-metil-1,3,4-oxadiazol-2-ilo con actividad inhibitoria de oga
|
|
WO2019037860A1
(en)
|
2017-08-24 |
2019-02-28 |
Asceneuron S.A. |
LINEAR INHIBITORS OF GLYCOSIDASE
|
|
WO2020039029A1
(en)
|
2018-08-22 |
2020-02-27 |
Asceneuron S. A. |
Spiro compounds as glycosidase inhibitors
|
|
IL280841B2
(en)
|
2018-08-22 |
2024-12-01 |
Asceneuron S A |
Succinate and fumarate acid addition salts of piperazine derivatives useful as glycosidase inhibitors
|
|
WO2020039027A1
(en)
|
2018-08-22 |
2020-02-27 |
Asceneuron S. A. |
Pyrrolidine glycosidase inhibitors
|
|
US20220143042A1
(en)
|
2019-02-22 |
2022-05-12 |
Asceneuron Sa |
Fused glycosidase inhibitors
|