JP2012529010A5 - - Google Patents

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JP2012529010A5
JP2012529010A5 JP2012513061A JP2012513061A JP2012529010A5 JP 2012529010 A5 JP2012529010 A5 JP 2012529010A5 JP 2012513061 A JP2012513061 A JP 2012513061A JP 2012513061 A JP2012513061 A JP 2012513061A JP 2012529010 A5 JP2012529010 A5 JP 2012529010A5
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JP2012513061A
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JP2012529010A (ja
JP5849045B2 (ja
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Priority claimed from PCT/US2010/001598 external-priority patent/WO2010141075A1/en
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JP2012513061A 2009-05-31 2010-06-01 試薬化合物、標識ストラテジーおよび質量分析ワークフローを用いたケトンおよびアルデヒド分析物の特異的分析 Expired - Fee Related JP5849045B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18274809P 2009-05-31 2009-05-31
US61/182,748 2009-05-31
PCT/US2010/001598 WO2010141075A1 (en) 2009-05-31 2010-06-01 Specific analysis of ketone and aldehyde analytes using reagent compounds labeling strategies, and mass spectrometry workflow

Publications (3)

Publication Number Publication Date
JP2012529010A JP2012529010A (ja) 2012-11-15
JP2012529010A5 true JP2012529010A5 (enExample) 2013-07-18
JP5849045B2 JP5849045B2 (ja) 2016-01-27

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JP2012513061A Expired - Fee Related JP5849045B2 (ja) 2009-05-31 2010-06-01 試薬化合物、標識ストラテジーおよび質量分析ワークフローを用いたケトンおよびアルデヒド分析物の特異的分析

Country Status (5)

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US (3) US20110003395A1 (enExample)
EP (1) EP2438448B1 (enExample)
JP (1) JP5849045B2 (enExample)
CA (1) CA2762277C (enExample)
WO (1) WO2010141075A1 (enExample)

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EP1868616A2 (en) * 2005-03-29 2007-12-26 The University of Maryland, Baltimore Inhibitors for extracellular signal-regulated kinase docking domains and uses therefor
GB0916881D0 (en) * 2009-09-25 2009-11-11 Electrophoretics Ltd Mass labels
US8309359B2 (en) * 2010-01-15 2012-11-13 California Institute Of Technology Isobaric tags for analyte detection and quantification
US8372653B2 (en) * 2010-01-22 2013-02-12 Dh Technologies Development Pte. Ltd. Mass tag reagents for simultaneous quantitation and identification of small molecules
US8617898B2 (en) 2010-01-25 2013-12-31 Dh Technologies Development Pte. Ltd. Quantitative analysis of vitamin D3, vitamin D2, and metabolites thereof
US9834578B2 (en) * 2010-05-27 2017-12-05 University Of Utah Research Foundation Enhanced sensitivity for analysis of ketosteroid compounds using mass spectrometry
EP3702774B1 (en) * 2011-02-07 2025-10-01 Laboratory Corporation of America Holdings Method for determining the presence or amount of testosterone in a sample
CN103782166B (zh) * 2011-06-06 2018-01-16 沃特世科技公司 用于定量样品中目标分析物的组合物、方法和试剂盒
CN104040343A (zh) * 2012-01-05 2014-09-10 Dh科技发展私人贸易有限公司 增强含有酮类固醇和酮基或醛的分析物的灵敏度和特异性
CN104040332B (zh) 2012-01-20 2017-10-20 Dh科技发展私人贸易有限公司 使用标记化学和lc‑msms工作流分析具有酚系oh的雌二醇和分析物
EP2850430B1 (en) * 2012-05-18 2017-04-19 Dh Technologies Development Pte. Ltd. Analysis of a panel of cerebrotendinous xanthomatosis biomarkers using site specific derivation and lc/ms/ms workflow
GB201215924D0 (en) 2012-09-06 2012-10-24 Univ Swansea Kit and method for quantitative detection of steroids
TW201619606A (zh) 2014-06-27 2016-06-01 脈動健康有限責任公司 用於羰基之偵測及定量之方法及裝置
WO2017087852A1 (en) * 2015-11-19 2017-05-26 The Arizona Board Of Regents On Behalf Of The University Of Arizona Stress biomarkers and related non-invasive detection methods
GB201521903D0 (en) * 2015-12-11 2016-01-27 Electrophoretics Ltd Isorbaric mass labels
CN107014846A (zh) * 2016-01-27 2017-08-04 沈阳药科大学 一种检测植物油过热处理的方法及其用途
CN107290459B (zh) * 2016-03-31 2019-12-06 中国科学院大连化学物理研究所 一种磷酸糖类物质的富集和固相衍生预处理方法
JP7153652B2 (ja) * 2017-01-31 2022-10-14 エフ．ホフマン－ラ ロシュ アーゲー 質量分析用の試薬
US20190041332A1 (en) 2017-08-01 2019-02-07 Pulse Health Llc Methods and Systems for Aldehyde Detection
CN108931603A (zh) * 2018-04-23 2018-12-04 国家烟草质量监督检验中心 一种基于稳定同位素标记质谱联用技术检测血浆中羧酸类代谢物的方法
JP7547313B2 (ja) 2018-07-24 2024-09-09 エフ． ホフマン－ラ ロシュ アーゲー 質量分析のための試薬
CN112449636A (zh) 2018-07-24 2021-03-05 豪夫迈·罗氏有限公司 用于质谱分析的试剂
EP3826994A1 (en) * 2018-07-24 2021-06-02 F. Hoffmann-La Roche AG Reagent for mass spectrometry
EP4623304A1 (en) * 2022-11-21 2025-10-01 F. Hoffmann-La Roche AG Derivatisation agent for laser desorption ionization mass spectrometry

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WO1996040662A2 (en) * 1995-06-07 1996-12-19 Cellpro, Incorporated Aminooxy-containing linker compounds and their application in conjugates
US7799576B2 (en) 2003-01-30 2010-09-21 Dh Technologies Development Pte. Ltd. Isobaric labels for mass spectrometric analysis of peptides and method thereof
WO2004097372A2 (en) * 2003-04-28 2004-11-11 The Regents Of The University Of California Element-coded affinity tags
US7369712B2 (en) 2003-09-30 2008-05-06 Fotonation Vision Limited Automated statistical self-calibrating detection and removal of blemishes in digital images based on multiple occurrences of dust in images
US7309608B2 (en) * 2003-09-30 2007-12-18 Hoa Duc Nguyen Method of analysis of aldehyde and ketone by mass spectrometry
US20050148771A1 (en) * 2004-01-05 2005-07-07 Applera Corporation. Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof
JP4832312B2 (ja) * 2004-01-05 2011-12-07 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 標識試薬および標識化分析物の混合物を含む、標識試薬、標識化分析物、およびそれらに由来するフラグメントイオン、ならびにそれらの分析方法
JP4566604B2 (ja) * 2004-03-31 2010-10-20 塩野義製薬株式会社 糖鎖標識試薬
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GB0518585D0 (en) * 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
JP2009520949A (ja) * 2005-11-16 2009-05-28 アンブルックス，インコーポレイテッド 非天然アミノ酸を含んでいる組成物および方法
EP2054540B1 (en) * 2006-05-26 2014-11-26 DH Technologies Development Pte. Ltd. Tagging reagents and methods for hydroxylated compounds

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