JP2012529010A5 - - Google Patents

Download PDF

Info

Publication number
JP2012529010A5
JP2012529010A5 JP2012513061A JP2012513061A JP2012529010A5 JP 2012529010 A5 JP2012529010 A5 JP 2012529010A5 JP 2012513061 A JP2012513061 A JP 2012513061A JP 2012513061 A JP2012513061 A JP 2012513061A JP 2012529010 A5 JP2012529010 A5 JP 2012529010A5
Authority
JP
Japan
Prior art keywords
labels
analyte
compounds
group
item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012513061A
Other languages
English (en)
Japanese (ja)
Other versions
JP5849045B2 (ja
JP2012529010A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/001598 external-priority patent/WO2010141075A1/en
Publication of JP2012529010A publication Critical patent/JP2012529010A/ja
Publication of JP2012529010A5 publication Critical patent/JP2012529010A5/ja
Application granted granted Critical
Publication of JP5849045B2 publication Critical patent/JP5849045B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012513061A 2009-05-31 2010-06-01 試薬化合物、標識ストラテジーおよび質量分析ワークフローを用いたケトンおよびアルデヒド分析物の特異的分析 Expired - Fee Related JP5849045B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18274809P 2009-05-31 2009-05-31
US61/182,748 2009-05-31
PCT/US2010/001598 WO2010141075A1 (en) 2009-05-31 2010-06-01 Specific analysis of ketone and aldehyde analytes using reagent compounds labeling strategies, and mass spectrometry workflow

Publications (3)

Publication Number Publication Date
JP2012529010A JP2012529010A (ja) 2012-11-15
JP2012529010A5 true JP2012529010A5 (enExample) 2013-07-18
JP5849045B2 JP5849045B2 (ja) 2016-01-27

Family

ID=43298006

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012513061A Expired - Fee Related JP5849045B2 (ja) 2009-05-31 2010-06-01 試薬化合物、標識ストラテジーおよび質量分析ワークフローを用いたケトンおよびアルデヒド分析物の特異的分析

Country Status (5)

Country Link
US (3) US20110003395A1 (enExample)
EP (1) EP2438448B1 (enExample)
JP (1) JP5849045B2 (enExample)
CA (1) CA2762277C (enExample)
WO (1) WO2010141075A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1868616A2 (en) * 2005-03-29 2007-12-26 The University of Maryland, Baltimore Inhibitors for extracellular signal-regulated kinase docking domains and uses therefor
GB0916881D0 (en) * 2009-09-25 2009-11-11 Electrophoretics Ltd Mass labels
US8309359B2 (en) * 2010-01-15 2012-11-13 California Institute Of Technology Isobaric tags for analyte detection and quantification
EP2526428B1 (en) * 2010-01-22 2016-03-30 DH Technologies Development Pte. Ltd. Mass tag reagents for simultaneous quantitation and identification of small molecules
WO2011091436A1 (en) 2010-01-25 2011-07-28 Dh Technologies Development Pte. Ltd. Quantitative analysis of vitamin d3, vitamin d2, and metabolites thereof
US9834578B2 (en) * 2010-05-27 2017-12-05 University Of Utah Research Foundation Enhanced sensitivity for analysis of ketosteroid compounds using mass spectrometry
EP2673631B1 (en) * 2011-02-07 2020-04-29 Laboratory Corporation of America Holdings Method for determining the presence or amount of testosterone in a sample
BR112013031284A2 (pt) * 2011-06-06 2016-12-06 Waters Technologies Corp composições, métodos, e kits para quantificar analitos alvo em uma amostra
CN104040343A (zh) * 2012-01-05 2014-09-10 Dh科技发展私人贸易有限公司 增强含有酮类固醇和酮基或醛的分析物的灵敏度和特异性
US9874575B2 (en) 2012-01-20 2018-01-23 Dh Technologies Development Pte. Ltd. Analysis of estradiol and analytes with phenolic OH using labeling chemistry and LC-MSMS workflow
CN104603617B (zh) * 2012-05-18 2017-04-12 Dh科技发展私人贸易有限公司 使用定点衍生化和lc/ms/ms工作流程分析一组脑腱黄瘤病生物
GB201215924D0 (en) * 2012-09-06 2012-10-24 Univ Swansea Kit and method for quantitative detection of steroids
JP2017527822A (ja) 2014-06-27 2017-09-21 パルス ヘルス エルエルシー 蛍光検出アセンブリ
WO2017087852A1 (en) * 2015-11-19 2017-05-26 The Arizona Board Of Regents On Behalf Of The University Of Arizona Stress biomarkers and related non-invasive detection methods
GB201521903D0 (en) * 2015-12-11 2016-01-27 Electrophoretics Ltd Isorbaric mass labels
CN107014846A (zh) * 2016-01-27 2017-08-04 沈阳药科大学 一种检测植物油过热处理的方法及其用途
CN107290459B (zh) * 2016-03-31 2019-12-06 中国科学院大连化学物理研究所 一种磷酸糖类物质的富集和固相衍生预处理方法
CN110383071B (zh) * 2017-01-31 2023-10-03 豪夫迈·罗氏有限公司 用于质谱的试剂
US20190041332A1 (en) 2017-08-01 2019-02-07 Pulse Health Llc Methods and Systems for Aldehyde Detection
CN108931603A (zh) * 2018-04-23 2018-12-04 国家烟草质量监督检验中心 一种基于稳定同位素标记质谱联用技术检测血浆中羧酸类代谢物的方法
WO2020020850A1 (en) * 2018-07-24 2020-01-30 F. Hoffmann-La Roche Ag Reagent for mass spectrometry
JP7547314B2 (ja) 2018-07-24 2024-09-09 エフ． ホフマン－ラ ロシュ アーゲー 質量分析のための試薬
EP3826994A1 (en) * 2018-07-24 2021-06-02 F. Hoffmann-La Roche AG Reagent for mass spectrometry
EP4405687A1 (en) * 2021-09-22 2024-07-31 DH Technologies Development Pte. Ltd. Ms/ms-based identification of trisulfide bonds
WO2024110385A1 (en) * 2022-11-21 2024-05-30 F. Hoffmann-La Roche Ag Derivatisation agent for laser desorption ionization mass spectrometry

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996040662A2 (en) * 1995-06-07 1996-12-19 Cellpro, Incorporated Aminooxy-containing linker compounds and their application in conjugates
EP1588145B1 (en) 2003-01-30 2011-07-06 Life Technologies Corporation Methods, mixtures, kits and compositions pertaining to analyte determination
WO2004097372A2 (en) * 2003-04-28 2004-11-11 The Regents Of The University Of California Element-coded affinity tags
US7309608B2 (en) * 2003-09-30 2007-12-18 Hoa Duc Nguyen Method of analysis of aldehyde and ketone by mass spectrometry
US7369712B2 (en) 2003-09-30 2008-05-06 Fotonation Vision Limited Automated statistical self-calibrating detection and removal of blemishes in digital images based on multiple occurrences of dust in images
JP4832312B2 (ja) * 2004-01-05 2011-12-07 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 標識試薬および標識化分析物の混合物を含む、標識試薬、標識化分析物、およびそれらに由来するフラグメントイオン、ならびにそれらの分析方法
US7307169B2 (en) 2004-01-05 2007-12-11 Applera Corporation Isotopically enriched N-substituted piperazines and methods for the preparation thereof
JP4566604B2 (ja) * 2004-03-31 2010-10-20 塩野義製薬株式会社 糖鎖標識試薬
US20060183238A1 (en) 2005-02-09 2006-08-17 Applera Corporation Amine-containing compound analysis methods
GB0518585D0 (en) * 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
EP1951890A4 (en) * 2005-11-16 2009-06-24 Ambrx Inc PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
EP2054540B1 (en) * 2006-05-26 2014-11-26 DH Technologies Development Pte. Ltd. Tagging reagents and methods for hydroxylated compounds

Similar Documents

Publication Publication Date Title
CN107064330B (zh) 通过质谱法定量胰岛素
Fuchs et al. Proteomics in nutrition research: principles, technologies and applications
Rathahao-Paris et al. High resolution mass spectrometry for structural identification of metabolites in metabolomics
Zhang et al. SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids
Reid et al. ‘Top down’protein characterization via tandem mass spectrometry
US20160139140A1 (en) Mass labels
EP2021805A2 (en) Expression quantification using mass spectrometry
WO2008142579A3 (en) Method of mass analysis of target molecules in complex mixtures
US9068995B2 (en) Method for determining derivatized analytes in a separated biological fluid
US20150212055A1 (en) Sensitive Method for Measuring Cis-Diol Containing Compounds in Plasma Using 2D-LC-MS/MS
EP2526428B1 (en) Mass tag reagents for simultaneous quantitation and identification of small molecules
JP2022534369A (ja) 代謝物を検出するための質量分析アッセイ法
WO2005114700A2 (en) Expression quantification using mass spectrometry
CN110044998B (zh) 通过质谱法定量他莫昔芬及其代谢物
CN110714064A (zh) 一种核酸质谱检测标准品、制备方法及其应用
JP2020512559A (ja) 包括的および定量的な脂質およびトコフェロールの分析
CN107085061A (zh) 基于hplc‑ms/ms检测平台的溶血磷脂酰胆碱的绝对定量分析方法
Fuente-Ballesteros et al. Development and validation of a green and practical method for studying pesticides and related chemical compounds in bee pollen samples by UAE-LC-QTOF-MS
Zhou et al. The spectra count label-free quantitation in cancer proteomics
JP2013076629A (ja) α２，６−シアロ糖鎖とα２，３−シアロ糖鎖とを識別する方法
JP2015516578A5 (enExample)
EP2850430B1 (en) Analysis of a panel of cerebrotendinous xanthomatosis biomarkers using site specific derivation and lc/ms/ms workflow
WO2004092707A3 (en) Aromatic phosphonium salts and their use as labeling reagents mass spectrometry analysis
CN112379009A (zh) 生物样本中类固醇激素的检测方法及该方法所用试剂盒
WO2006109485A1 (ja) 質量分析法