JP2012529010A5 - - Google Patents

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JP2012529010A5
JP2012529010A5 JP2012513061A JP2012513061A JP2012529010A5 JP 2012529010 A5 JP2012529010 A5 JP 2012529010A5 JP 2012513061 A JP2012513061 A JP 2012513061A JP 2012513061 A JP2012513061 A JP 2012513061A JP 2012529010 A5 JP2012529010 A5 JP 2012529010A5
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JP2012513061A
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JP5849045B2 (ja
JP2012529010A (ja
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Priority claimed from PCT/US2010/001598 external-priority patent/WO2010141075A1/en
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JP2012513061A 2009-05-31 2010-06-01 試薬化合物、標識ストラテジーおよび質量分析ワークフローを用いたケトンおよびアルデヒド分析物の特異的分析 Expired - Fee Related JP5849045B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18274809P 2009-05-31 2009-05-31
US61/182,748 2009-05-31
PCT/US2010/001598 WO2010141075A1 (en) 2009-05-31 2010-06-01 Specific analysis of ketone and aldehyde analytes using reagent compounds labeling strategies, and mass spectrometry workflow

Publications (3)

Publication Number Publication Date
JP2012529010A JP2012529010A (ja) 2012-11-15
JP2012529010A5 true JP2012529010A5 (enExample) 2013-07-18
JP5849045B2 JP5849045B2 (ja) 2016-01-27

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JP2012513061A Expired - Fee Related JP5849045B2 (ja) 2009-05-31 2010-06-01 試薬化合物、標識ストラテジーおよび質量分析ワークフローを用いたケトンおよびアルデヒド分析物の特異的分析

Country Status (5)

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US (3) US20110003395A1 (enExample)
EP (1) EP2438448B1 (enExample)
JP (1) JP5849045B2 (enExample)
CA (1) CA2762277C (enExample)
WO (1) WO2010141075A1 (enExample)

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US20090299063A1 (en) * 2005-03-29 2009-12-03 Paul Shapiro Inhibitors for Extracellular Signal-Regulated Kinase Docking Domains and Uses Therefor
GB0916881D0 (en) * 2009-09-25 2009-11-11 Electrophoretics Ltd Mass labels
WO2011088423A2 (en) * 2010-01-15 2011-07-21 California Institute Of Technology Isobaric tags for analyte detection and quantification
JP5855581B2 (ja) * 2010-01-22 2016-02-09 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 小分子の同時的な定量および同定のための質量タグ試薬
US8617898B2 (en) 2010-01-25 2013-12-31 Dh Technologies Development Pte. Ltd. Quantitative analysis of vitamin D3, vitamin D2, and metabolites thereof
US9834578B2 (en) * 2010-05-27 2017-12-05 University Of Utah Research Foundation Enhanced sensitivity for analysis of ketosteroid compounds using mass spectrometry
US9029162B2 (en) * 2011-02-07 2015-05-12 Laboratory Corporation Of America Holdings Methods and systems for determining the presence or amount of testosterone in a sample
US9768001B2 (en) * 2011-06-06 2017-09-19 Waters Technologies Corporation Compositions, methods, and kits for quantifying target analytes in a sample
CN104040343A (zh) * 2012-01-05 2014-09-10 Dh科技发展私人贸易有限公司 增强含有酮类固醇和酮基或醛的分析物的灵敏度和特异性
US9874575B2 (en) 2012-01-20 2018-01-23 Dh Technologies Development Pte. Ltd. Analysis of estradiol and analytes with phenolic OH using labeling chemistry and LC-MSMS workflow
US10078091B2 (en) * 2012-05-18 2018-09-18 Dh Technologies Development Pte. Ltd. Analysis of a panel of cerebrotendinous xanthomatosis biomarkers using site specific derivation and LC/MS/MS workflow
GB201215924D0 (en) 2012-09-06 2012-10-24 Univ Swansea Kit and method for quantitative detection of steroids
US9546930B2 (en) 2014-06-27 2017-01-17 Pulse Heath Llc Analysis cartridge
US10996205B2 (en) * 2015-11-19 2021-05-04 Arizona Board Of Regents On Behalf Of The University Of Arizona Stress biomarkers and related non-invasive detection methods
GB201521903D0 (en) * 2015-12-11 2016-01-27 Electrophoretics Ltd Isorbaric mass labels
CN107014846A (zh) * 2016-01-27 2017-08-04 沈阳药科大学 一种检测植物油过热处理的方法及其用途
CN107290459B (zh) * 2016-03-31 2019-12-06 中国科学院大连化学物理研究所 一种磷酸糖类物质的富集和固相衍生预处理方法
JP7153652B2 (ja) * 2017-01-31 2022-10-14 エフ．ホフマン－ラ ロシュ アーゲー 質量分析用の試薬
US20190041332A1 (en) 2017-08-01 2019-02-07 Pulse Health Llc Methods and Systems for Aldehyde Detection
CN108931603A (zh) * 2018-04-23 2018-12-04 国家烟草质量监督检验中心 一种基于稳定同位素标记质谱联用技术检测血浆中羧酸类代谢物的方法
JP7547315B2 (ja) * 2018-07-24 2024-09-09 エフ． ホフマン－ラ ロシュ アーゲー 質量分析のための試薬
WO2020020850A1 (en) * 2018-07-24 2020-01-30 F. Hoffmann-La Roche Ag Reagent for mass spectrometry
JP7547314B2 (ja) 2018-07-24 2024-09-09 エフ． ホフマン－ラ ロシュ アーゲー 質量分析のための試薬
WO2023047304A1 (en) * 2021-09-22 2023-03-30 Dh Technologies Development Pte. Ltd. Ms/ms-based identification of trisulfide bonds
CN120225880A (zh) * 2022-11-21 2025-06-27 豪夫迈·罗氏有限公司 用于激光解吸电离质谱的衍生化剂

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WO1996040662A2 (en) * 1995-06-07 1996-12-19 Cellpro, Incorporated Aminooxy-containing linker compounds and their application in conjugates
US20040219685A1 (en) 2003-01-30 2004-11-04 Applera Corporation Methods and mixtures pertaining to analyte determination using electrophilic labeling reagents
WO2004097372A2 (en) * 2003-04-28 2004-11-11 The Regents Of The University Of California Element-coded affinity tags
US7309608B2 (en) * 2003-09-30 2007-12-18 Hoa Duc Nguyen Method of analysis of aldehyde and ketone by mass spectrometry
US7369712B2 (en) 2003-09-30 2008-05-06 Fotonation Vision Limited Automated statistical self-calibrating detection and removal of blemishes in digital images based on multiple occurrences of dust in images
US20050148771A1 (en) 2004-01-05 2005-07-07 Applera Corporation. Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof
JP4832312B2 (ja) * 2004-01-05 2011-12-07 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 標識試薬および標識化分析物の混合物を含む、標識試薬、標識化分析物、およびそれらに由来するフラグメントイオン、ならびにそれらの分析方法
JP4566604B2 (ja) * 2004-03-31 2010-10-20 塩野義製薬株式会社 糖鎖標識試薬
US20060183238A1 (en) 2005-02-09 2006-08-17 Applera Corporation Amine-containing compound analysis methods
GB0518585D0 (en) * 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
EP1951890A4 (en) * 2005-11-16 2009-06-24 Ambrx Inc PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
EP2054540B1 (en) * 2006-05-26 2014-11-26 DH Technologies Development Pte. Ltd. Tagging reagents and methods for hydroxylated compounds

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