JP2012525134A5 - - Google Patents
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- Publication number
- JP2012525134A5 JP2012525134A5 JP2012507784A JP2012507784A JP2012525134A5 JP 2012525134 A5 JP2012525134 A5 JP 2012525134A5 JP 2012507784 A JP2012507784 A JP 2012507784A JP 2012507784 A JP2012507784 A JP 2012507784A JP 2012525134 A5 JP2012525134 A5 JP 2012525134A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- protein
- ectodomain
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000018102 proteins Nutrition 0.000 claims 26
- 108090000623 proteins and genes Proteins 0.000 claims 26
- 102000004169 proteins and genes Human genes 0.000 claims 26
- 125000003275 alpha amino acid group Chemical group 0.000 claims 22
- 241000712461 unidentified influenza virus Species 0.000 claims 21
- 239000000203 mixture Substances 0.000 claims 20
- 230000035931 haemagglutination Effects 0.000 claims 17
- 239000012634 fragment Substances 0.000 claims 10
- 241000712431 Influenza A virus Species 0.000 claims 8
- 101710154606 Hemagglutinin Proteins 0.000 claims 7
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 7
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 7
- 101710176177 Protein A56 Proteins 0.000 claims 7
- 239000002245 particle Substances 0.000 claims 7
- 101710132601 Capsid protein Proteins 0.000 claims 5
- 101710094648 Coat protein Proteins 0.000 claims 5
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 claims 5
- 101710125418 Major capsid protein Proteins 0.000 claims 5
- 101710141454 Nucleoprotein Proteins 0.000 claims 5
- 101710083689 Probable capsid protein Proteins 0.000 claims 5
- 230000003067 hemagglutinative effect Effects 0.000 claims 5
- 229960005486 vaccine Drugs 0.000 claims 5
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 4
- 241001515965 unidentified phage Species 0.000 claims 4
- 241001534160 Escherichia virus Qbeta Species 0.000 claims 3
- 125000000539 amino acid group Chemical group 0.000 claims 3
- 125000003277 amino group Chemical group 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 3
- 241000713196 Influenza B virus Species 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 101900159346 Influenza A virus Hemagglutinin Proteins 0.000 claims 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 241000831652 Salinivibrio sharmensis Species 0.000 claims 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09159262.6 | 2009-04-30 | ||
| EP09159262 | 2009-04-30 | ||
| PCT/EP2010/055944 WO2010125202A1 (en) | 2009-04-30 | 2010-04-30 | Influenza hemagglutinin compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012525134A JP2012525134A (ja) | 2012-10-22 |
| JP2012525134A5 true JP2012525134A5 (enExample) | 2013-06-06 |
Family
ID=42790940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012507784A Pending JP2012525134A (ja) | 2009-04-30 | 2010-04-30 | インフルエンザ赤血球凝集素の組成物とその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120263743A1 (enExample) |
| EP (1) | EP2424570A1 (enExample) |
| JP (1) | JP2012525134A (enExample) |
| CN (1) | CN102573915B (enExample) |
| AU (1) | AU2010243490A1 (enExample) |
| CA (1) | CA2759873A1 (enExample) |
| NZ (1) | NZ596058A (enExample) |
| SG (1) | SG175382A1 (enExample) |
| WO (1) | WO2010125202A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106822887A (zh) * | 2017-01-26 | 2017-06-13 | 中国科学院微生物研究所 | 一种流感病毒四价亚单位疫苗及其应用 |
| MA55313A (fr) * | 2019-03-13 | 2022-01-19 | Generation Bio Co | Vecteurs d'adn non viraux et leurs utilisations pour exprimer des agents thérapeutiques du facteur viii |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU781396B2 (en) * | 1999-07-20 | 2005-05-19 | Morphosys Ag | Novel methods for displaying (poly)peptides/proteins on bacteriophage particles via disulfide bonds |
| US7320793B2 (en) * | 2001-01-19 | 2008-01-22 | Cytos Biotechnology Ag | Molecular antigen array |
| EP2196217A1 (en) * | 2001-09-14 | 2010-06-16 | Cytos Biotechnology AG | Packaging of immunostimulatory substances into virus-like particles: method of preparation and use |
| CN100509057C (zh) * | 2001-11-07 | 2009-07-08 | 赛托斯生物技术公司 | 用于治疗骨病的抗原阵列 |
| RU2324704C2 (ru) * | 2002-07-17 | 2008-05-20 | Цитос Байотекнолоджи Аг | Молекулярные массивы антигенов |
| KR20060031607A (ko) * | 2003-07-10 | 2006-04-12 | 사이토스 바이오테크놀로지 아게 | 패킹된 바이러스-양 입자 |
| CN101023103A (zh) * | 2004-09-21 | 2007-08-22 | 赛托斯生物技术公司 | 包含ap205外壳蛋白和抗原性多肽的融合蛋白的病毒样颗粒 |
| JP2008513035A (ja) * | 2004-09-21 | 2008-05-01 | サイトス バイオテクノロジー アーゲー | Ａｐ２０５のコートタンパク質と抗原性ポリペプチドとの融合タンパク質を含んでなるウイルス粒子 |
| WO2007011904A2 (en) * | 2005-07-19 | 2007-01-25 | Dow Global Technologies Inc. | Recombinant flu vaccines |
| CN101605558A (zh) * | 2005-08-16 | 2009-12-16 | 夏威夷生物技术公司 | 流感重组亚单位疫苗 |
| JP5714799B2 (ja) * | 2005-10-18 | 2015-05-07 | ノババックス インコーポレイテッド | 機能的インフルエンザウイルス様粒子（ｖｌｐ） |
| WO2007068747A1 (en) * | 2005-12-14 | 2007-06-21 | Cytos Biotechnology Ag | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
| CU23576A1 (es) * | 2006-02-28 | 2010-09-30 | Ct Ingenieria Genetica Biotech | Antígenos vacunales quiméricos contra el virus de la influenza aviar |
| CN101394864A (zh) * | 2006-03-07 | 2009-03-25 | 法克斯因内特公司 | 包含血细胞凝集素的组合物、制造其的方法与使用其的方法 |
| CA2638760A1 (en) * | 2006-03-07 | 2007-09-13 | Vaxinnate Corporation | Compositions that include hemagglutinin, methods of making and methods of use thereof |
-
2010
- 2010-04-30 AU AU2010243490A patent/AU2010243490A1/en not_active Abandoned
- 2010-04-30 WO PCT/EP2010/055944 patent/WO2010125202A1/en not_active Ceased
- 2010-04-30 CN CN201080019069.9A patent/CN102573915B/zh not_active Expired - Fee Related
- 2010-04-30 CA CA2759873A patent/CA2759873A1/en not_active Abandoned
- 2010-04-30 EP EP10719754A patent/EP2424570A1/en not_active Withdrawn
- 2010-04-30 NZ NZ596058A patent/NZ596058A/xx not_active IP Right Cessation
- 2010-04-30 US US13/318,099 patent/US20120263743A1/en not_active Abandoned
- 2010-04-30 JP JP2012507784A patent/JP2012525134A/ja active Pending
- 2010-04-30 SG SG2011079225A patent/SG175382A1/en unknown
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