JP2019534242A5 - - Google Patents
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- Publication number
- JP2019534242A5 JP2019534242A5 JP2019511574A JP2019511574A JP2019534242A5 JP 2019534242 A5 JP2019534242 A5 JP 2019534242A5 JP 2019511574 A JP2019511574 A JP 2019511574A JP 2019511574 A JP2019511574 A JP 2019511574A JP 2019534242 A5 JP2019534242 A5 JP 2019534242A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- charged amino
- positively charged
- region
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 26
- 239000000203 mixture Substances 0.000 claims 21
- 150000001413 amino acids Chemical class 0.000 claims 20
- 229920001184 polypeptide Polymers 0.000 claims 12
- 102000004196 processed proteins & peptides Human genes 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 229910052757 nitrogen Inorganic materials 0.000 claims 11
- 238000006467 substitution reaction Methods 0.000 claims 8
- 101710154606 Hemagglutinin Proteins 0.000 claims 6
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 6
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 6
- 101710176177 Protein A56 Proteins 0.000 claims 6
- 239000000185 hemagglutinin Substances 0.000 claims 6
- 208000037797 influenza A Diseases 0.000 claims 6
- 229910052698 phosphorus Inorganic materials 0.000 claims 5
- 230000002163 immunogen Effects 0.000 claims 4
- 239000002671 adjuvant Substances 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 241000712431 Influenza A virus Species 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 230000036755 cellular response Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000012895 dilution Substances 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022209044A JP7762643B2 (ja) | 2016-08-25 | 2022-12-26 | 免疫原性組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1614485.9 | 2016-08-25 | ||
| GBGB1614485.9A GB201614485D0 (en) | 2016-08-25 | 2016-08-25 | Immunogenic composition |
| PCT/GB2017/052510 WO2018037246A1 (en) | 2016-08-25 | 2017-08-25 | Immunogenic composition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022209044A Division JP7762643B2 (ja) | 2016-08-25 | 2022-12-26 | 免疫原性組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019534242A JP2019534242A (ja) | 2019-11-28 |
| JP2019534242A5 true JP2019534242A5 (enExample) | 2020-10-01 |
| JP7203015B2 JP7203015B2 (ja) | 2023-01-12 |
Family
ID=57119951
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511574A Active JP7203015B2 (ja) | 2016-08-25 | 2017-08-25 | 免疫原性組成物 |
| JP2022209044A Active JP7762643B2 (ja) | 2016-08-25 | 2022-12-26 | 免疫原性組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022209044A Active JP7762643B2 (ja) | 2016-08-25 | 2022-12-26 | 免疫原性組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11123422B2 (enExample) |
| EP (1) | EP3504235A1 (enExample) |
| JP (2) | JP7203015B2 (enExample) |
| CN (1) | CN109923125B (enExample) |
| AU (3) | AU2017315238A1 (enExample) |
| CA (1) | CA3034328A1 (enExample) |
| GB (1) | GB201614485D0 (enExample) |
| WO (1) | WO2018037246A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201614485D0 (en) * | 2016-08-25 | 2016-10-12 | Univ Oxford Innovation Ltd | Immunogenic composition |
| US12064478B2 (en) | 2018-09-21 | 2024-08-20 | Nutech Ventures | Methods of making and using universal centralized influenza vaccine genes |
| GB2578163A (en) * | 2018-10-19 | 2020-04-22 | Univ Pretoria | Plant produced avian influenza antigens and their uses in diagnostic assays and devices |
| GB202204478D0 (en) * | 2022-03-29 | 2022-05-11 | Univ Oxford Innovation Ltd | Immunogenic compositions |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| CA2035576A1 (en) | 1990-02-07 | 1991-08-08 | Alexander R. Neurath | Conformational epitopes of human immunodeficiency virus envelope glycoprotein gp120 hiv-1 |
| CZ300688B6 (cs) | 1995-09-01 | 2009-07-15 | Corixa Corporation | Polypeptid, farmaceutický prostredek a vakcína s jeho obsahem, zpusob prípravy a použití polypeptidu, molekula rekombinantní DNA a její použití, expresní vektor, hostitelská bunka, fúsní porotein a diagnostický kit |
| EP1490101A4 (en) * | 2002-03-05 | 2006-09-20 | Univ Texas | PROCESS FOR IMPROVING IMMUNE INDUCTION WITH MDA-7 |
| KR20080052509A (ko) * | 2005-04-11 | 2008-06-11 | 더 거버먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 애즈 레프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비시즈, 센터스 포 디지즈 컨트롤 앤드 프리벤션 | 유행성 독감 바이러스에 대한 백신 |
| JP2009537147A (ja) | 2006-05-15 | 2009-10-29 | シー レーン バイオテクノロジーズ， エルエルシー | インフルエンザウイルスに対する中和抗体 |
| JP2010500034A (ja) * | 2006-08-09 | 2010-01-07 | メッドイミューン バクシーンズ，インコーポレイティド | インフルエンザ赤血球凝集素変異体およびノイラミニダーゼ変異体 |
| KR101745925B1 (ko) | 2008-07-18 | 2017-06-12 | 메디카고 인코포레이티드 | 신규 인플루엔자 바이러스 면역화 에피토프 |
| MX340735B (es) | 2010-04-09 | 2016-07-22 | Univ Utrecht Holding Bv | Proteinas multimericas recombinantes de la influenza. |
| WO2012021786A2 (en) * | 2010-08-12 | 2012-02-16 | Theraclone Sciences, Inc. | Anti-hemagglutinin antibody compositions and methods of use thereof |
| US8883171B2 (en) | 2010-09-14 | 2014-11-11 | University of Pittsburgh—of the Commonwealth System of Higher Education | Computationally optimized broadly reactive antigens for influenza |
| WO2012089231A1 (en) | 2010-12-30 | 2012-07-05 | Okairòs Ag | Paramyxovirus vaccines |
| WO2013177444A2 (en) * | 2012-05-23 | 2013-11-28 | The Board Of Trustees Of The Leland Stanford Junior University | Influenza vaccine constructs |
| US8932598B2 (en) * | 2012-08-28 | 2015-01-13 | Vaxinnate Corporation | Fusion proteins and methods of use |
| JP2016516415A (ja) | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
| GB201614485D0 (en) * | 2016-08-25 | 2016-10-12 | Univ Oxford Innovation Ltd | Immunogenic composition |
-
2016
- 2016-08-25 GB GBGB1614485.9A patent/GB201614485D0/en not_active Ceased
-
2017
- 2017-08-25 US US16/326,749 patent/US11123422B2/en active Active
- 2017-08-25 JP JP2019511574A patent/JP7203015B2/ja active Active
- 2017-08-25 EP EP17758932.2A patent/EP3504235A1/en active Pending
- 2017-08-25 CA CA3034328A patent/CA3034328A1/en active Pending
- 2017-08-25 WO PCT/GB2017/052510 patent/WO2018037246A1/en not_active Ceased
- 2017-08-25 AU AU2017315238A patent/AU2017315238A1/en not_active Abandoned
- 2017-08-25 CN CN201780051719.XA patent/CN109923125B/zh active Active
-
2021
- 2021-08-27 US US17/458,712 patent/US12390518B2/en active Active
-
2022
- 2022-12-26 JP JP2022209044A patent/JP7762643B2/ja active Active
-
2024
- 2024-10-28 AU AU2024227680A patent/AU2024227680A1/en active Pending
-
2026
- 2026-01-05 AU AU2026200025A patent/AU2026200025A1/en active Pending
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