JP2012523432A - 虚血再灌流に関係する浮腫を治療する方法 - Google Patents

虚血再灌流に関係する浮腫を治療する方法 Download PDF

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Publication number
JP2012523432A
JP2012523432A JP2012504890A JP2012504890A JP2012523432A JP 2012523432 A JP2012523432 A JP 2012523432A JP 2012504890 A JP2012504890 A JP 2012504890A JP 2012504890 A JP2012504890 A JP 2012504890A JP 2012523432 A JP2012523432 A JP 2012523432A
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tissue
compound
group
organ
lung
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Japanese (ja)
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JP2012523432A5 (https=
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マイケル イーガン トーマス
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University of North Carolina at Chapel Hill
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University of North Carolina at Chapel Hill
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Publication of JP2012523432A publication Critical patent/JP2012523432A/ja
Publication of JP2012523432A5 publication Critical patent/JP2012523432A5/ja
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2012504890A 2009-04-09 2010-04-09 虚血再灌流に関係する浮腫を治療する方法 Pending JP2012523432A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16808909P 2009-04-09 2009-04-09
US61/168,089 2009-04-09
PCT/US2010/030556 WO2010118334A1 (en) 2009-04-09 2010-04-09 Methods of treating edema related to ischemia-reperfusion

Publications (2)

Publication Number Publication Date
JP2012523432A true JP2012523432A (ja) 2012-10-04
JP2012523432A5 JP2012523432A5 (https=) 2013-05-16

Family

ID=42936599

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012504890A Pending JP2012523432A (ja) 2009-04-09 2010-04-09 虚血再灌流に関係する浮腫を治療する方法

Country Status (14)

Country Link
US (1) US20120064044A1 (https=)
EP (1) EP2416651A4 (https=)
JP (1) JP2012523432A (https=)
KR (1) KR20120005025A (https=)
CN (1) CN102458113A (https=)
AU (1) AU2010233151A1 (https=)
BR (1) BRPI1010516A2 (https=)
CA (1) CA2757998A1 (https=)
EA (1) EA201101349A1 (https=)
IL (1) IL215604A0 (https=)
MX (1) MX2011010616A (https=)
SG (1) SG175133A1 (https=)
WO (1) WO2010118334A1 (https=)
ZA (1) ZA201107815B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100135886A (ko) * 2008-04-09 2010-12-27 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법
EP2681314B1 (en) * 2011-03-03 2017-11-01 Quark Pharmaceuticals, Inc. Compositions and methods for treating lung disease and injury
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof
CN116622006B (zh) 2017-03-10 2025-05-30 北卡罗来纳大学查珀尔希尔分校 短效的基于肝素的抗凝血剂化合物和方法
US11993627B2 (en) 2017-07-03 2024-05-28 The University Of North Carolina At Chapel Hill Enzymatic synthesis of homogeneous chondroitin sulfate oligosaccharides
JP7495061B2 (ja) 2017-11-03 2024-06-04 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 抗炎症作用を有する硫酸化オリゴ糖
JP7362667B2 (ja) 2018-02-12 2023-10-17 イニミューン・コーポレーション Ｔｏｌｌ様受容体リガンド
CN112437667B (zh) 2018-06-20 2024-05-28 北卡罗来纳大学查珀尔希尔分校 细胞保护方法和组合物
JP7801217B2 (ja) 2019-11-13 2026-01-16 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 肝虚血再灌流障害におけるヘパラン硫酸（ｈｓ）オリゴ糖の効果

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05139992A (ja) * 1991-11-13 1993-06-08 Ajinomoto Co Inc ヒトａｄｆを含有する臓器保護剤
WO2004085396A1 (ja) * 2003-03-26 2004-10-07 Mitsubishi Pharma Corporation 虚血再灌流障害の予防または治療剤、臓器保存剤およびスクリーニング方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6113918A (en) * 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US7960522B2 (en) * 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
US7928132B2 (en) * 2004-08-06 2011-04-19 Ohio University Methods for the amelioration of episodes of acute or chronic ulcerative colitis
US20060211752A1 (en) * 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
EP2170366B1 (en) * 2007-08-03 2013-11-06 Opsona Therapeutics Limited Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage
KR20100135886A (ko) * 2008-04-09 2010-12-27 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05139992A (ja) * 1991-11-13 1993-06-08 Ajinomoto Co Inc ヒトａｄｆを含有する臓器保護剤
WO2004085396A1 (ja) * 2003-03-26 2004-10-07 Mitsubishi Pharma Corporation 虚血再灌流障害の予防または治療剤、臓器保存剤およびスクリーニング方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6014021492; ＢＡＺＩＮ，　Ｈ．Ｇ．　ｅｔ　ａｌ．: Ｂｉｏｏｒｇａｎｉｃ　＆　Ｍｅｄｉｃｉｎａｌ　Ｃｈｅｍｉｓｔｒｙ　Ｌｅｔｔｅｒｓ Ｖｏｌ．１８, 2008, ｐ．５３５０-５３５４ *
JPN6014021493; ＣＡＳＩＲＡＧＨＩ，　Ｍ．　ｅｔ　ａｌ．: Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｈｅａｒｔ　ａｎｄ　Ｌｕｎｇ　Ｔｒａｎｓｐｌａｎｔａｔｉｏｎ Ｖｏｌ．２７，　Ｎｏ．２Ｓ, 2008, Ｓ２１４-２１５ *

Also Published As

Publication number Publication date
MX2011010616A (es) 2012-03-14
CN102458113A (zh) 2012-05-16
SG175133A1 (en) 2011-12-29
CA2757998A1 (en) 2010-10-14
KR20120005025A (ko) 2012-01-13
EA201101349A1 (ru) 2012-05-30
ZA201107815B (en) 2013-04-24
IL215604A0 (en) 2011-12-29
AU2010233151A1 (en) 2011-11-17
EP2416651A4 (en) 2014-03-26
US20120064044A1 (en) 2012-03-15
WO2010118334A1 (en) 2010-10-14
BRPI1010516A2 (pt) 2015-08-25
EP2416651A1 (en) 2012-02-15

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