JP2012522762A5 - - Google Patents
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- Publication number
- JP2012522762A5 JP2012522762A5 JP2012502872A JP2012502872A JP2012522762A5 JP 2012522762 A5 JP2012522762 A5 JP 2012522762A5 JP 2012502872 A JP2012502872 A JP 2012502872A JP 2012502872 A JP2012502872 A JP 2012502872A JP 2012522762 A5 JP2012522762 A5 JP 2012522762A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- group
- igfbp7
- dermatitis
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102100029228 Insulin-like growth factor-binding protein 7 Human genes 0.000 claims 10
- 108010008598 insulin-like growth factor binding protein-related protein 1 Proteins 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 230000003463 hyperproliferative effect Effects 0.000 claims 6
- 210000002510 keratinocyte Anatomy 0.000 claims 6
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 238000001126 phototherapy Methods 0.000 claims 5
- 201000004624 Dermatitis Diseases 0.000 claims 4
- 201000004681 Psoriasis Diseases 0.000 claims 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 230000001575 pathological effect Effects 0.000 claims 3
- 238000007910 systemic administration Methods 0.000 claims 3
- 206010012438 Dermatitis atopic Diseases 0.000 claims 2
- 206010012442 Dermatitis contact Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 206010033733 Papule Diseases 0.000 claims 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 2
- 229930003316 Vitamin D Natural products 0.000 claims 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 2
- 201000008937 atopic dermatitis Diseases 0.000 claims 2
- 239000003124 biologic agent Substances 0.000 claims 2
- 229940046731 calcineurin inhibitors Drugs 0.000 claims 2
- 230000001684 chronic effect Effects 0.000 claims 2
- 239000011280 coal tar Substances 0.000 claims 2
- 208000010247 contact dermatitis Diseases 0.000 claims 2
- 239000003246 corticosteroid Substances 0.000 claims 2
- 229960001334 corticosteroids Drugs 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003018 immunosuppressive agent Substances 0.000 claims 2
- 229940124589 immunosuppressive drug Drugs 0.000 claims 2
- 239000002596 immunotoxin Substances 0.000 claims 2
- 229940051026 immunotoxin Drugs 0.000 claims 2
- 230000002637 immunotoxin Effects 0.000 claims 2
- 231100000608 immunotoxin Toxicity 0.000 claims 2
- 201000011486 lichen planus Diseases 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 2
- 229960004889 salicylic acid Drugs 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 102000003390 tumor necrosis factor Human genes 0.000 claims 2
- 235000019166 vitamin D Nutrition 0.000 claims 2
- 239000011710 vitamin D Substances 0.000 claims 2
- 150000003710 vitamin D derivatives Chemical class 0.000 claims 2
- 229940046008 vitamin d Drugs 0.000 claims 2
- NUZWLKWWNNJHPT-UHFFFAOYSA-N anthralin Chemical compound C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O NUZWLKWWNNJHPT-UHFFFAOYSA-N 0.000 claims 1
- 229960002311 dithranol Drugs 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000003906 humectant Substances 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 229940046728 tumor necrosis factor alpha inhibitor Drugs 0.000 claims 1
- 239000002451 tumor necrosis factor inhibitor Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20276009P | 2009-04-01 | 2009-04-01 | |
| US61/202,760 | 2009-04-01 | ||
| PCT/IL2010/000167 WO2010113146A1 (en) | 2009-04-01 | 2010-02-28 | A method of regulating proliferation and differentiation of keratinocyes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012522762A JP2012522762A (ja) | 2012-09-27 |
| JP2012522762A5 true JP2012522762A5 (enExample) | 2013-04-18 |
Family
ID=42245610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012502872A Pending JP2012522762A (ja) | 2009-04-01 | 2010-02-28 | ケラチノサイトの増殖および分化を調節する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8912142B2 (enExample) |
| EP (1) | EP2344179A1 (enExample) |
| JP (1) | JP2012522762A (enExample) |
| CN (1) | CN102448484A (enExample) |
| AU (1) | AU2010231514A1 (enExample) |
| CA (1) | CA2759201A1 (enExample) |
| MX (1) | MX2011010401A (enExample) |
| WO (1) | WO2010113146A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010113146A1 (en) | 2009-04-01 | 2010-10-07 | The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | A method of regulating proliferation and differentiation of keratinocyes |
| US20130123647A1 (en) | 2011-05-03 | 2013-05-16 | The Research Foundation Of State University Of New York | Methods Useful in Optimizing the Treatment of Neuropathies and Targeting Tissues with Cosmetic Botulinum Injections |
| US9687669B2 (en) | 2011-11-09 | 2017-06-27 | John Stephan | Wearable light therapy apparatus |
| CN104394883B (zh) * | 2012-07-04 | 2017-05-31 | 悉尼大学 | 炎性皮肤病症的治疗 |
| DE102013213252A1 (de) * | 2013-07-05 | 2015-01-08 | Schülke & Mayr GmbH | Verwendung eines Isopropanol enthaltenden Mittels zur Bekämpfung von Caliciviridae |
| JP6608382B2 (ja) * | 2014-02-26 | 2019-11-20 | ルマ セラピューティクス，インク． | 紫外光治療装置及び方法 |
| US11028138B2 (en) * | 2016-07-02 | 2021-06-08 | Virongy L.L.C. | Compositions and methods for using actin-based peptides to modulate cellular bioactivity and cellular susceptibility to intracellular pathogens |
| US20190083809A1 (en) | 2016-07-27 | 2019-03-21 | Z2020, Llc | Componentry and devices for light therapy delivery and methods related thereto |
| US11147618B2 (en) | 2017-01-11 | 2021-10-19 | Medtronic Advanced Energy Llc | Electrosurgical unit and system |
| CN107881240B (zh) * | 2017-12-27 | 2018-10-02 | 北京泱深生物信息技术有限公司 | 骨肉瘤的诊治标志物 |
| GB201808723D0 (en) * | 2018-05-29 | 2018-07-11 | Univ Birmingham | Treatment of hyperproliferative disorders |
| US12109253B2 (en) | 2019-01-30 | 2024-10-08 | Agency For Science, Technology And Research | Use of IGFBP7 for treating malaria |
| US20230022117A1 (en) * | 2019-12-04 | 2023-01-26 | Musc Foundation For Research Development | RNAi-BASED TARGETING COMPOUNDS AND USES THEREOF TO PREVENT ACQUIRED HEARING LOSS |
| CN115212302A (zh) * | 2022-08-03 | 2022-10-21 | 中国人民解放军空军军医大学 | 抗igfbp7抗体在治疗皮肤病中的应用 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3155591A (en) | 1961-12-06 | 1964-11-03 | Witco Chemical Corp | Hair rinse compostions of polyoxypropylene quaternary ammonium compounds |
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3755560A (en) | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
| US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
| US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3959461A (en) | 1974-05-28 | 1976-05-25 | The United States Of America As Represented By The Secretary Of Agriculture | Hair cream rinse formulations containing quaternary ammonium salts |
| US3929678A (en) | 1974-08-01 | 1975-12-30 | Procter & Gamble | Detergent composition having enhanced particulate soil removal performance |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4036945A (en) | 1976-05-03 | 1977-07-19 | The Massachusetts General Hospital | Composition and method for determining the size and location of myocardial infarcts |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| LU76955A1 (enExample) | 1977-03-15 | 1978-10-18 | ||
| US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US4387090A (en) | 1980-12-22 | 1983-06-07 | The Procter & Gamble Company | Hair conditioning compositions |
| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| US4421769A (en) | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US5151210A (en) | 1985-07-25 | 1992-09-29 | The Procter & Gamble Company | Shampoo compositions |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5151209A (en) | 1987-11-19 | 1992-09-29 | The Procter & Gamble Company | Shampoo compositions |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5011681A (en) | 1989-10-11 | 1991-04-30 | Richardson-Vicks, Inc. | Facial cleansing compositions |
| US5120532A (en) | 1990-04-06 | 1992-06-09 | The Procter & Gamble Company | Hair styling shampoos |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5073371A (en) | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
| US5073372A (en) | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
| US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| JP2878528B2 (ja) | 1992-07-21 | 1999-04-05 | 株式会社日立製作所 | 磁気記録再生装置 |
| WO1994020063A2 (en) * | 1993-03-04 | 1994-09-15 | Cytoven International N.V. | Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof |
| US5667487A (en) | 1993-04-07 | 1997-09-16 | Henley; Julian L. | Ionosonic drug delivery apparatus |
| US5541110A (en) | 1994-05-17 | 1996-07-30 | Bristol-Myers Squibb | Cloning and expression of a gene encoding bryodin 1 from Bryonia dioica |
| US5807718A (en) | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| US5691380A (en) | 1995-06-29 | 1997-11-25 | The Procter & Gamble Company | Stable n-acetylcysteine compositions and methods for treating human skin therewith |
| CA2290443A1 (en) | 1997-05-14 | 1998-11-19 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Peptide parathyroid hormone analogs |
| GB9811171D0 (en) | 1998-05-22 | 1998-07-22 | Royal Free Hosp School Med | Viral vector |
| JP2002516325A (ja) * | 1998-05-26 | 2002-06-04 | スミスクライン・ビーチャム・コーポレイション | 新規な置換イミダゾール化合物 |
| US6348185B1 (en) | 1998-06-20 | 2002-02-19 | Washington University School Of Medicine | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
| US7393548B2 (en) | 1999-03-22 | 2008-07-01 | J.P. M.E.D. Ltd. | Nano oil in glycerin emulsion |
| AUPR030900A0 (en) * | 2000-09-22 | 2000-10-12 | Queensland University Of Technology | Growth factor complex |
| AU2005316599A1 (en) * | 2004-12-14 | 2006-06-22 | Vertex Pharmaceuticals Incorporated | Pyrimidine inhibitors of ERK protein kinase and uses therof |
| AU2006299079A1 (en) * | 2005-09-30 | 2007-04-12 | Universiteit Maastricht | Tumor angiogenesis associated genes and a method for their identification |
| WO2009036188A2 (en) * | 2007-09-11 | 2009-03-19 | University Of Massachusetts | Insulin-like growth factor binding protein 7 for treatment of cancer |
| WO2010113146A1 (en) | 2009-04-01 | 2010-10-07 | The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | A method of regulating proliferation and differentiation of keratinocyes |
-
2010
- 2010-02-28 WO PCT/IL2010/000167 patent/WO2010113146A1/en not_active Ceased
- 2010-02-28 AU AU2010231514A patent/AU2010231514A1/en not_active Abandoned
- 2010-02-28 CA CA2759201A patent/CA2759201A1/en not_active Abandoned
- 2010-02-28 CN CN2010800240522A patent/CN102448484A/zh active Pending
- 2010-02-28 MX MX2011010401A patent/MX2011010401A/es not_active Application Discontinuation
- 2010-02-28 EP EP10710105A patent/EP2344179A1/en not_active Withdrawn
- 2010-02-28 US US13/127,058 patent/US8912142B2/en not_active Expired - Fee Related
- 2010-02-28 JP JP2012502872A patent/JP2012522762A/ja active Pending
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