CN102448484A - 调节角质化细胞增生和分化的方法 - Google Patents
调节角质化细胞增生和分化的方法 Download PDFInfo
- Publication number
- CN102448484A CN102448484A CN2010800240522A CN201080024052A CN102448484A CN 102448484 A CN102448484 A CN 102448484A CN 2010800240522 A CN2010800240522 A CN 2010800240522A CN 201080024052 A CN201080024052 A CN 201080024052A CN 102448484 A CN102448484 A CN 102448484A
- Authority
- CN
- China
- Prior art keywords
- igfbp7
- keratinocytes
- expression
- cells
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20276009P | 2009-04-01 | 2009-04-01 | |
| US61/202,760 | 2009-04-01 | ||
| PCT/IL2010/000167 WO2010113146A1 (en) | 2009-04-01 | 2010-02-28 | A method of regulating proliferation and differentiation of keratinocyes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102448484A true CN102448484A (zh) | 2012-05-09 |
Family
ID=42245610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800240522A Pending CN102448484A (zh) | 2009-04-01 | 2010-02-28 | 调节角质化细胞增生和分化的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8912142B2 (enExample) |
| EP (1) | EP2344179A1 (enExample) |
| JP (1) | JP2012522762A (enExample) |
| CN (1) | CN102448484A (enExample) |
| AU (1) | AU2010231514A1 (enExample) |
| CA (1) | CA2759201A1 (enExample) |
| MX (1) | MX2011010401A (enExample) |
| WO (1) | WO2010113146A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107881240A (zh) * | 2017-12-27 | 2018-04-06 | 北京泱深生物信息技术有限公司 | 骨肉瘤的诊治标志物 |
| CN109689867A (zh) * | 2016-07-02 | 2019-04-26 | 富荣吉有限责任公司 | 利用基于肌动蛋白的肽调节细胞生物活性和细胞对胞内病原体易感性的组合物和方法 |
| CN115212302A (zh) * | 2022-08-03 | 2022-10-21 | 中国人民解放军空军军医大学 | 抗igfbp7抗体在治疗皮肤病中的应用 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010113146A1 (en) | 2009-04-01 | 2010-10-07 | The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | A method of regulating proliferation and differentiation of keratinocyes |
| US20130123647A1 (en) | 2011-05-03 | 2013-05-16 | The Research Foundation Of State University Of New York | Methods Useful in Optimizing the Treatment of Neuropathies and Targeting Tissues with Cosmetic Botulinum Injections |
| US9687669B2 (en) | 2011-11-09 | 2017-06-27 | John Stephan | Wearable light therapy apparatus |
| CN104394883B (zh) * | 2012-07-04 | 2017-05-31 | 悉尼大学 | 炎性皮肤病症的治疗 |
| DE102013213252A1 (de) * | 2013-07-05 | 2015-01-08 | Schülke & Mayr GmbH | Verwendung eines Isopropanol enthaltenden Mittels zur Bekämpfung von Caliciviridae |
| JP6608382B2 (ja) * | 2014-02-26 | 2019-11-20 | ルマ セラピューティクス,インク. | 紫外光治療装置及び方法 |
| US20190083809A1 (en) | 2016-07-27 | 2019-03-21 | Z2020, Llc | Componentry and devices for light therapy delivery and methods related thereto |
| US11147618B2 (en) | 2017-01-11 | 2021-10-19 | Medtronic Advanced Energy Llc | Electrosurgical unit and system |
| GB201808723D0 (en) * | 2018-05-29 | 2018-07-11 | Univ Birmingham | Treatment of hyperproliferative disorders |
| US12109253B2 (en) | 2019-01-30 | 2024-10-08 | Agency For Science, Technology And Research | Use of IGFBP7 for treating malaria |
| US20230022117A1 (en) * | 2019-12-04 | 2023-01-26 | Musc Foundation For Research Development | RNAi-BASED TARGETING COMPOUNDS AND USES THEREOF TO PREVENT ACQUIRED HEARING LOSS |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1541107A (zh) * | 2000-09-22 | 2004-10-27 | ��ʿ����ѧ | 生长因子复合物 |
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| US3155591A (en) | 1961-12-06 | 1964-11-03 | Witco Chemical Corp | Hair rinse compostions of polyoxypropylene quaternary ammonium compounds |
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| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3755560A (en) | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
| US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
| US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3959461A (en) | 1974-05-28 | 1976-05-25 | The United States Of America As Represented By The Secretary Of Agriculture | Hair cream rinse formulations containing quaternary ammonium salts |
| US3929678A (en) | 1974-08-01 | 1975-12-30 | Procter & Gamble | Detergent composition having enhanced particulate soil removal performance |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4036945A (en) | 1976-05-03 | 1977-07-19 | The Massachusetts General Hospital | Composition and method for determining the size and location of myocardial infarcts |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| LU76955A1 (enExample) | 1977-03-15 | 1978-10-18 | ||
| US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US4387090A (en) | 1980-12-22 | 1983-06-07 | The Procter & Gamble Company | Hair conditioning compositions |
| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| US4421769A (en) | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
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| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
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| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
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| WO2009036188A2 (en) * | 2007-09-11 | 2009-03-19 | University Of Massachusetts | Insulin-like growth factor binding protein 7 for treatment of cancer |
| WO2010113146A1 (en) | 2009-04-01 | 2010-10-07 | The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | A method of regulating proliferation and differentiation of keratinocyes |
-
2010
- 2010-02-28 WO PCT/IL2010/000167 patent/WO2010113146A1/en not_active Ceased
- 2010-02-28 AU AU2010231514A patent/AU2010231514A1/en not_active Abandoned
- 2010-02-28 CA CA2759201A patent/CA2759201A1/en not_active Abandoned
- 2010-02-28 CN CN2010800240522A patent/CN102448484A/zh active Pending
- 2010-02-28 MX MX2011010401A patent/MX2011010401A/es not_active Application Discontinuation
- 2010-02-28 EP EP10710105A patent/EP2344179A1/en not_active Withdrawn
- 2010-02-28 US US13/127,058 patent/US8912142B2/en not_active Expired - Fee Related
- 2010-02-28 JP JP2012502872A patent/JP2012522762A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1541107A (zh) * | 2000-09-22 | 2004-10-27 | ��ʿ����ѧ | 生长因子复合物 |
Non-Patent Citations (3)
| Title |
|---|
| J.SCHMITT,Z.ZHANG 等: "Efficacy and tolerability of biologic and nonbiologic systemic treatments for moderate-to-severe psoriasis: meta-analysis of randomized controlled trials", 《BRITISH JOURNAL OF DERMATOLOGY》 * |
| M.HOCHBERG,S.ZELIGSON 等: "Genomic-scale analysis of psoriatic skin reveals differentially expressed insulin-like growth factor-binding protein-7 after phototherapy", 《PHOTOBIOLOGY》 * |
| YOUNGMAN OH 等: "Synthesis and Characterization of Insulin-like Growth Factor-binding Protein (IGFBP)-7", 《THE JOURNAL OF BIOLOGICAL CHEMISTRY》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109689867A (zh) * | 2016-07-02 | 2019-04-26 | 富荣吉有限责任公司 | 利用基于肌动蛋白的肽调节细胞生物活性和细胞对胞内病原体易感性的组合物和方法 |
| CN107881240A (zh) * | 2017-12-27 | 2018-04-06 | 北京泱深生物信息技术有限公司 | 骨肉瘤的诊治标志物 |
| CN107881240B (zh) * | 2017-12-27 | 2018-10-02 | 北京泱深生物信息技术有限公司 | 骨肉瘤的诊治标志物 |
| CN115212302A (zh) * | 2022-08-03 | 2022-10-21 | 中国人民解放军空军军医大学 | 抗igfbp7抗体在治疗皮肤病中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8912142B2 (en) | 2014-12-16 |
| US20110207665A1 (en) | 2011-08-25 |
| JP2012522762A (ja) | 2012-09-27 |
| WO2010113146A1 (en) | 2010-10-07 |
| CA2759201A1 (en) | 2010-10-07 |
| EP2344179A1 (en) | 2011-07-20 |
| AU2010231514A1 (en) | 2011-11-03 |
| MX2011010401A (es) | 2012-01-20 |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120509 |