JP2012522225A5 - - Google Patents
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- Publication number
- JP2012522225A5 JP2012522225A5 JP2012502288A JP2012502288A JP2012522225A5 JP 2012522225 A5 JP2012522225 A5 JP 2012522225A5 JP 2012502288 A JP2012502288 A JP 2012502288A JP 2012502288 A JP2012502288 A JP 2012502288A JP 2012522225 A5 JP2012522225 A5 JP 2012522225A5
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- cell according
- membrane
- fluid cell
- silicon nitride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 claims 40
- 210000004027 cell Anatomy 0.000 claims 20
- 239000012528 membrane Substances 0.000 claims 15
- 229910052581 Si3N4 Inorganic materials 0.000 claims 8
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 claims 8
- 239000007790 solid phase Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 108020004414 DNA Proteins 0.000 claims 6
- 102000053602 DNA Human genes 0.000 claims 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- 239000000090 biomarker Substances 0.000 claims 3
- 238000005286 illumination Methods 0.000 claims 3
- 239000010410 layer Substances 0.000 claims 3
- 230000003287 optical effect Effects 0.000 claims 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 2
- 239000012062 aqueous buffer Substances 0.000 claims 2
- AIYUHDOJVYHVIT-UHFFFAOYSA-M caesium chloride Chemical compound [Cl-].[Cs+] AIYUHDOJVYHVIT-UHFFFAOYSA-M 0.000 claims 2
- 239000003989 dielectric material Substances 0.000 claims 2
- 238000003384 imaging method Methods 0.000 claims 2
- 238000000399 optical microscopy Methods 0.000 claims 2
- 229910052710 silicon Inorganic materials 0.000 claims 2
- 239000010703 silicon Substances 0.000 claims 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- 230000008033 biological extinction Effects 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21126009P | 2009-03-26 | 2009-03-26 | |
| US61/211,260 | 2009-03-26 | ||
| PCT/US2010/028845 WO2010111602A1 (en) | 2009-03-26 | 2010-03-26 | Method for imaging on thin solid-state interface between two fluids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012522225A JP2012522225A (ja) | 2012-09-20 |
| JP2012522225A5 true JP2012522225A5 (enExample) | 2013-05-16 |
| JP5687683B2 JP5687683B2 (ja) | 2015-03-18 |
Family
ID=42781550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012502288A Expired - Fee Related JP5687683B2 (ja) | 2009-03-26 | 2010-03-26 | ２種類の流体間の薄い固相界面上における撮像方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120135410A1 (enExample) |
| EP (1) | EP2411790A4 (enExample) |
| JP (1) | JP5687683B2 (enExample) |
| KR (1) | KR20110133617A (enExample) |
| CN (2) | CN105928910A (enExample) |
| AU (1) | AU2010229774A1 (enExample) |
| CA (1) | CA2756233A1 (enExample) |
| IL (2) | IL215351A (enExample) |
| WO (1) | WO2010111602A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3543357A1 (en) | 2007-05-08 | 2019-09-25 | Trustees of Boston University | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof |
| CN102698827B (zh) * | 2012-07-04 | 2014-03-05 | 中国民航大学 | 固液双层模型可伸缩柔性承载装置 |
| US9651539B2 (en) | 2012-10-28 | 2017-05-16 | Quantapore, Inc. | Reducing background fluorescence in MEMS materials by low energy ion beam treatment |
| WO2014190322A2 (en) | 2013-05-24 | 2014-11-27 | Quantapore, Inc. | Nanopore-based nucleic acid analysis with mixed fret detection |
| DE102014101172A1 (de) * | 2014-01-30 | 2015-07-30 | Jpk Instruments Ag | Anordnung für ein optisches Messsystem zum Bestimmen einer Probe und Probenkammeranordnung |
| EP3204519B1 (en) | 2014-10-10 | 2020-04-29 | Quantapore Inc. | Nanopore-based polymer analysis with mutually-quenching fluorescent labels |
| JP6757316B2 (ja) | 2014-10-24 | 2020-09-16 | クアンタポール， インコーポレイテッド | ナノ構造のアレイを使用するポリマーの効率的光学分析 |
| EP3402903B1 (en) * | 2016-01-15 | 2022-03-02 | Quantapore, Inc. | Optically-based nanopore analysis with reduced background |
| CN109219664A (zh) | 2016-05-31 | 2019-01-15 | 昆塔波尔公司 | 双色纳米孔测序 |
| EP3482196B1 (en) | 2016-07-05 | 2022-02-23 | Quantapore, Inc. | Optically based nanopore sequencing |
| WO2018034807A1 (en) | 2016-08-19 | 2018-02-22 | Quantapore, Inc. | Optically-based nanopore sequencing using quenching agents |
| US10409052B2 (en) * | 2016-09-28 | 2019-09-10 | University Of Washington | Inverted light-sheet microscope |
| CN107860752B (zh) * | 2017-10-23 | 2020-06-23 | 清华大学 | 一种交流电模式下的纳米孔单分子荧光成像装置及方法 |
| US11499962B2 (en) | 2017-11-17 | 2022-11-15 | Ultima Genomics, Inc. | Methods and systems for analyte detection and analysis |
| US10512911B1 (en) * | 2018-12-07 | 2019-12-24 | Ultima Genomics, Inc. | Implementing barriers for controlled environments during sample processing and detection |
| US12239980B2 (en) | 2018-12-07 | 2025-03-04 | Ultima Genomics, Inc. | Implementing barriers for controlled environments during sample processing and detection |
| GB201902810D0 (en) * | 2019-03-01 | 2019-04-17 | Vidya Holdings Ltd | Disposition of reagents in assay device |
| CN111855623B (zh) * | 2019-04-25 | 2022-09-30 | 北京大学 | 一种光电联用检测仪 |
| CN113607714B (zh) * | 2021-10-08 | 2022-01-11 | 成都齐碳科技有限公司 | 分子膜成膜或表征器件、装置、方法以及生物芯片 |
| CN115011463A (zh) * | 2022-07-08 | 2022-09-06 | 西湖大学 | 一种细胞调控设备 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5485536A (en) * | 1994-10-13 | 1996-01-16 | Accuphotonics, Inc. | Fiber optic probe for near field optical microscopy |
| JPH102860A (ja) * | 1996-06-17 | 1998-01-06 | Olympus Optical Co Ltd | 微小物質検鏡装置 |
| EP1009802B1 (en) * | 1997-02-12 | 2004-08-11 | Eugene Y. Chan | Methods for analyzimg polymers |
| US7244349B2 (en) * | 1997-12-17 | 2007-07-17 | Molecular Devices Corporation | Multiaperture sample positioning and analysis system |
| EP1006199A1 (en) * | 1998-12-03 | 2000-06-07 | Kreatech Biotechnology B.V. | Applications with and methods for producing selected interstrand crosslinks in nucleic acid |
| DE10042840A1 (de) * | 2000-08-30 | 2002-03-14 | Leica Microsystems | Vorrichtung und Verfahren zur Anregung von Fluoreszenzmikroskopmarkern bei der Mehrphotonen-Rastermikroskopie |
| US7919308B2 (en) * | 2002-06-14 | 2011-04-05 | Agilent Technologies, Inc. | Form in place gaskets for assays |
| CN1266283C (zh) * | 2003-02-14 | 2006-07-26 | 中国科学院上海原子核研究所 | Dna单分子有序化测序方法 |
| US7501279B2 (en) * | 2003-04-03 | 2009-03-10 | University Of Washington | Microwell arrays with nanoholes |
| US20050053974A1 (en) * | 2003-05-20 | 2005-03-10 | University Of Maryland | Apparatus and methods for surface plasmon-coupled directional emission |
| EP1548444A1 (en) * | 2003-12-23 | 2005-06-29 | Paul Scherrer Institut | An assay chip, and uses of said assay chip to determine molecular structures and functions |
| JP2006038816A (ja) * | 2004-07-30 | 2006-02-09 | Nara Institute Of Science & Technology | マイクロアレイ読取装置 |
| WO2006137891A2 (en) * | 2004-09-29 | 2006-12-28 | University Of Florida Research Foundation, Inc. | Membrane with nanochannels for detection of molecules |
| US20070070349A1 (en) * | 2005-09-23 | 2007-03-29 | Helicos Biosciences Corporation | Optical train and method for TIRF single molecule detection and analysis |
| JP4395748B2 (ja) * | 2004-11-29 | 2010-01-13 | ソニー株式会社 | ノイズ蛍光処理方法 |
| CA2606440A1 (en) * | 2005-04-29 | 2006-11-09 | University Of Rochester | Ultrathin porous nanoscale membranes, methods of making, and uses thereof |
| EP3543357A1 (en) * | 2007-05-08 | 2019-09-25 | Trustees of Boston University | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof |
| EP2034338A1 (en) * | 2007-08-11 | 2009-03-11 | ETH Zurich | Liquid Lens System |
-
2010
- 2010-03-26 EP EP10756919.6A patent/EP2411790A4/en not_active Withdrawn
- 2010-03-26 CA CA2756233A patent/CA2756233A1/en not_active Abandoned
- 2010-03-26 JP JP2012502288A patent/JP5687683B2/ja not_active Expired - Fee Related
- 2010-03-26 WO PCT/US2010/028845 patent/WO2010111602A1/en not_active Ceased
- 2010-03-26 CN CN201610204864.4A patent/CN105928910A/zh active Pending
- 2010-03-26 KR KR1020117025267A patent/KR20110133617A/ko not_active Withdrawn
- 2010-03-26 CN CN201080019523.0A patent/CN102414555B/zh not_active Expired - Fee Related
- 2010-03-26 AU AU2010229774A patent/AU2010229774A1/en not_active Abandoned
-
2011
- 2011-09-25 IL IL215351A patent/IL215351A/en not_active IP Right Cessation
- 2011-09-26 US US13/245,261 patent/US20120135410A1/en not_active Abandoned
-
2016
- 2016-04-10 IL IL245019A patent/IL245019A0/en unknown
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