CN105928910A - 在两液体间的薄固态界面上成像的方法 - Google Patents

在两液体间的薄固态界面上成像的方法 Download PDF

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Publication number
CN105928910A
CN105928910A CN201610204864.4A CN201610204864A CN105928910A CN 105928910 A CN105928910 A CN 105928910A CN 201610204864 A CN201610204864 A CN 201610204864A CN 105928910 A CN105928910 A CN 105928910A
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China
Prior art keywords
solid film
optical
light
refractive index
liquid
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CN201610204864.4A
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English (en)
Chinese (zh)
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G·V·索尼
A·梅勒
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Boston University
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Boston University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0088—Inverse microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Optical Measuring Cells (AREA)
  • Microscoopes, Condenser (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201610204864.4A 2009-03-26 2010-03-26 在两液体间的薄固态界面上成像的方法 Pending CN105928910A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21126009P 2009-03-26 2009-03-26
US61/211,260 2009-03-26
CN201080019523.0A CN102414555B (zh) 2009-03-26 2010-03-26 在两液体间的薄固态界面上成像的方法

Related Parent Applications (1)

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CN201080019523.0A Division CN102414555B (zh) 2009-03-26 2010-03-26 在两液体间的薄固态界面上成像的方法

Publications (1)

Publication Number Publication Date
CN105928910A true CN105928910A (zh) 2016-09-07

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CN201610204864.4A Pending CN105928910A (zh) 2009-03-26 2010-03-26 在两液体间的薄固态界面上成像的方法
CN201080019523.0A Expired - Fee Related CN102414555B (zh) 2009-03-26 2010-03-26 在两液体间的薄固态界面上成像的方法

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Country Link
US (1) US20120135410A1 (enExample)
EP (1) EP2411790A4 (enExample)
JP (1) JP5687683B2 (enExample)
KR (1) KR20110133617A (enExample)
CN (2) CN105928910A (enExample)
AU (1) AU2010229774A1 (enExample)
CA (1) CA2756233A1 (enExample)
IL (2) IL215351A (enExample)
WO (1) WO2010111602A1 (enExample)

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CN111855623A (zh) * 2019-04-25 2020-10-30 北京大学 一种光电联用检测仪

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EP3543357A1 (en) 2007-05-08 2019-09-25 Trustees of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
CN102698827B (zh) * 2012-07-04 2014-03-05 中国民航大学 固液双层模型可伸缩柔性承载装置
US9651539B2 (en) 2012-10-28 2017-05-16 Quantapore, Inc. Reducing background fluorescence in MEMS materials by low energy ion beam treatment
WO2014190322A2 (en) 2013-05-24 2014-11-27 Quantapore, Inc. Nanopore-based nucleic acid analysis with mixed fret detection
DE102014101172A1 (de) * 2014-01-30 2015-07-30 Jpk Instruments Ag Anordnung für ein optisches Messsystem zum Bestimmen einer Probe und Probenkammeranordnung
EP3204519B1 (en) 2014-10-10 2020-04-29 Quantapore Inc. Nanopore-based polymer analysis with mutually-quenching fluorescent labels
JP6757316B2 (ja) 2014-10-24 2020-09-16 クアンタポール， インコーポレイテッド ナノ構造のアレイを使用するポリマーの効率的光学分析
EP3402903B1 (en) * 2016-01-15 2022-03-02 Quantapore, Inc. Optically-based nanopore analysis with reduced background
CN109219664A (zh) 2016-05-31 2019-01-15 昆塔波尔公司 双色纳米孔测序
EP3482196B1 (en) 2016-07-05 2022-02-23 Quantapore, Inc. Optically based nanopore sequencing
WO2018034807A1 (en) 2016-08-19 2018-02-22 Quantapore, Inc. Optically-based nanopore sequencing using quenching agents
US10409052B2 (en) * 2016-09-28 2019-09-10 University Of Washington Inverted light-sheet microscope
CN107860752B (zh) * 2017-10-23 2020-06-23 清华大学 一种交流电模式下的纳米孔单分子荧光成像装置及方法
US11499962B2 (en) 2017-11-17 2022-11-15 Ultima Genomics, Inc. Methods and systems for analyte detection and analysis
US10512911B1 (en) * 2018-12-07 2019-12-24 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
US12239980B2 (en) 2018-12-07 2025-03-04 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
GB201902810D0 (en) * 2019-03-01 2019-04-17 Vidya Holdings Ltd Disposition of reagents in assay device
CN113607714B (zh) * 2021-10-08 2022-01-11 成都齐碳科技有限公司 分子膜成膜或表征器件、装置、方法以及生物芯片
CN115011463A (zh) * 2022-07-08 2022-09-06 西湖大学 一种细胞调控设备

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US20060240543A1 (en) * 2003-04-03 2006-10-26 Albert Folch Microwell arrays with nanoholes
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Publication number Priority date Publication date Assignee Title
CN111855623A (zh) * 2019-04-25 2020-10-30 北京大学 一种光电联用检测仪

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Publication number Publication date
JP5687683B2 (ja) 2015-03-18
WO2010111602A1 (en) 2010-09-30
JP2012522225A (ja) 2012-09-20
CN102414555A (zh) 2012-04-11
AU2010229774A1 (en) 2011-11-17
CA2756233A1 (en) 2010-09-30
IL215351A (en) 2016-04-21
IL245019A0 (en) 2016-05-31
KR20110133617A (ko) 2011-12-13
CN102414555B (zh) 2016-05-04
EP2411790A4 (en) 2017-10-25
EP2411790A1 (en) 2012-02-01
IL215351A0 (en) 2011-12-29
US20120135410A1 (en) 2012-05-31

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Application publication date: 20160907