JP2012518072A - 明検出のためのクエンチャー付加デンドリマー色素 - Google Patents

明検出のためのクエンチャー付加デンドリマー色素 Download PDF

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Publication number
JP2012518072A
JP2012518072A JP2011551166A JP2011551166A JP2012518072A JP 2012518072 A JP2012518072 A JP 2012518072A JP 2011551166 A JP2011551166 A JP 2011551166A JP 2011551166 A JP2011551166 A JP 2011551166A JP 2012518072 A JP2012518072 A JP 2012518072A
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compound
activator
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fluorescence
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JP2012518072A5 (https=
Inventor
ピー．ブリュシェ マーセル
エー．エルンスト ローレン
フィッツパトリック ジェイムズ
セント−ジェルジ クリス
エフ．シュミット ブリジット
ワゴナー アラン
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Carnegie Mellon University
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Publication of JP2012518072A5 publication Critical patent/JP2012518072A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/10—Amino derivatives of triarylmethanes
    • C09B11/22—Amino derivatives of triarylmethanes containing OH groups bound to an aryl nucleus and their ethers and esters
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/02—Diaryl- or thriarylmethane dyes derived from diarylmethanes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/06—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/083—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines five >CH- groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
JP2011551166A 2009-02-18 2010-02-16 明検出のためのクエンチャー付加デンドリマー色素 Pending JP2012518072A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20792909P 2009-02-18 2009-02-18
US61/207,929 2009-02-18
PCT/US2010/024320 WO2010096388A2 (en) 2009-02-18 2010-02-16 Quenched dendrimeric dyes for bright detection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015157711A Division JP2016014033A (ja) 2009-02-18 2015-08-07 明検出のためのクエンチャー付加デンドリマー色素

Publications (2)

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JP2012518072A true JP2012518072A (ja) 2012-08-09
JP2012518072A5 JP2012518072A5 (https=) 2015-10-01

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JP2011551166A Pending JP2012518072A (ja) 2009-02-18 2010-02-16 明検出のためのクエンチャー付加デンドリマー色素
JP2015157711A Pending JP2016014033A (ja) 2009-02-18 2015-08-07 明検出のためのクエンチャー付加デンドリマー色素

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JP2015157711A Pending JP2016014033A (ja) 2009-02-18 2015-08-07 明検出のためのクエンチャー付加デンドリマー色素

Country Status (5)

Country Link
US (1) US9249306B2 (https=)
EP (1) EP2398860B1 (https=)
JP (2) JP2012518072A (https=)
CA (1) CA2752854A1 (https=)
WO (1) WO2010096388A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023057173A (ja) * 2017-06-16 2023-04-20 デューク ユニバーシティ 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2023538231A (ja) * 2020-07-23 2023-09-07 エンゾー バイオケム，インコーポレイテッド 蛍光クエンチャーポリマーコンジュゲート及びその使用

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WO2011150079A1 (en) * 2010-05-25 2011-12-01 Carnegie Mellon University Targeted probes of cellular physiology
US9023998B2 (en) * 2013-02-25 2015-05-05 Carnegie Mellon University Near infrared fluorogen and fluorescent activating proteins for in vivo imaging and live-cell biosensing
CN104250380B (zh) * 2013-06-25 2017-02-01 中国石油化工股份有限公司 一种树枝状聚合物和树枝状聚合物单体及其制备方法和应用
US9475894B2 (en) 2013-06-25 2016-10-25 China Petroleum & Chemical Corporation Dendritic polymer, dendritic polymer monomer, and hyperbranched copolymer
CN107429075B (zh) 2014-11-17 2022-11-01 卡内基梅隆大学 可激活的双组份光敏剂
US20180318454A1 (en) * 2015-11-04 2018-11-08 Duke University Conjugated polycationic polymers, methods of using the same and methods of treating autoimmune diseases, infectious diseases and acute radiation exposure
CN106867970B (zh) * 2017-01-22 2020-08-18 杭州市农业科学研究院 一种分泌抗孔雀石绿单克隆抗体的杂交瘤细胞株及其应用
US11058675B2 (en) 2018-03-29 2021-07-13 Carnegie Mellon University Cell-based screening and compounds that modulate GaINAc-transferases
CN110208441A (zh) * 2019-01-17 2019-09-06 广西科技大学 淡水鱼中隐性孔雀石绿的快速提取和检测方法
EP4666071A2 (en) * 2023-02-13 2025-12-24 Nautilus Subsidiary, Inc. Affinity reagents having artificial polymer scaffolds
CN119119767B (zh) * 2024-03-15 2025-09-05 浙江大学杭州国际科创中心 一种复杂基质中细胞荧光染色用的复方染料

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023057173A (ja) * 2017-06-16 2023-04-20 デューク ユニバーシティ 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP7601432B2 (ja) 2017-06-16 2024-12-17 デューク ユニバーシティ 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2023538231A (ja) * 2020-07-23 2023-09-07 エンゾー バイオケム，インコーポレイテッド 蛍光クエンチャーポリマーコンジュゲート及びその使用

Also Published As

Publication number Publication date
US9249306B2 (en) 2016-02-02
US20120058494A1 (en) 2012-03-08
EP2398860A2 (en) 2011-12-28
WO2010096388A3 (en) 2011-05-19
WO2010096388A4 (en) 2011-07-21
WO2010096388A2 (en) 2010-08-26
JP2016014033A (ja) 2016-01-28
CA2752854A1 (en) 2010-08-26
EP2398860B1 (en) 2013-11-20

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