JP2012513391A5 - - Google Patents
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- Publication number
- JP2012513391A5 JP2012513391A5 JP2011542223A JP2011542223A JP2012513391A5 JP 2012513391 A5 JP2012513391 A5 JP 2012513391A5 JP 2011542223 A JP2011542223 A JP 2011542223A JP 2011542223 A JP2011542223 A JP 2011542223A JP 2012513391 A5 JP2012513391 A5 JP 2012513391A5
- Authority
- JP
- Japan
- Prior art keywords
- mixture
- reacted
- produce
- hours
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 5
- XKJCHHZQLQNZHY-UHFFFAOYSA-N phthalimide Chemical class C1=CC=C2C(=O)NC(=O)C2=C1 XKJCHHZQLQNZHY-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000002425 crystallisation Methods 0.000 claims 1
- 230000008025 crystallization Effects 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- -1 linker compound Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229920001451 polypropylene glycol Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13968908P | 2008-12-22 | 2008-12-22 | |
| US61/139,689 | 2008-12-22 | ||
| PCT/US2009/066917 WO2010074935A1 (en) | 2008-12-22 | 2009-12-07 | Synthesis of obtaining modified polyethylene glycol intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012513391A JP2012513391A (ja) | 2012-06-14 |
| JP2012513391A5 true JP2012513391A5 (enExample) | 2012-12-27 |
Family
ID=41818624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011542223A Pending JP2012513391A (ja) | 2008-12-22 | 2009-12-07 | 修飾ポリエチレングリコール中間体を得るための合成法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8536375B2 (enExample) |
| EP (1) | EP2370501A1 (enExample) |
| JP (1) | JP2012513391A (enExample) |
| CN (1) | CN102325823B (enExample) |
| WO (1) | WO2010074935A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102353479B1 (ko) * | 2017-11-06 | 2022-01-21 | 한미정밀화학주식회사 | 폴리에틸렌글리콜 유도체 및 이의 제조방법 |
| IL281212B2 (en) | 2018-09-07 | 2023-12-01 | Merck Patent Gmbh | 5-Morpholin-4-yl-pyrazolo[4,3-B]pyridine derivatives and their use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6858409B1 (en) | 1988-05-27 | 2005-02-22 | Amgen Inc. | Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors |
| JP3693671B2 (ja) * | 1991-03-15 | 2005-09-07 | アムゲン インコーポレーテッド | ポリペプチドのｐｅｇ化 |
| EP1664316B1 (en) | 2003-09-15 | 2012-08-29 | Protiva Biotherapeutics Inc. | Polyethyleneglycol-modified lipid compounds and uses thereof |
| ES2402850T3 (es) * | 2008-02-28 | 2013-05-09 | Ge Healthcare Limited | Síntesis de un resto de PEG-6 a partir de productos químicos comerciales de bajo coste |
-
2009
- 2009-12-07 WO PCT/US2009/066917 patent/WO2010074935A1/en not_active Ceased
- 2009-12-07 US US13/141,337 patent/US8536375B2/en not_active Expired - Fee Related
- 2009-12-07 JP JP2011542223A patent/JP2012513391A/ja active Pending
- 2009-12-07 EP EP09768296A patent/EP2370501A1/en not_active Withdrawn
- 2009-12-07 CN CN200980157390.0A patent/CN102325823B/zh not_active Expired - Fee Related
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