JP2012511033A - 多価化合物の可逆阻害用マスキングリガンド - Google Patents
多価化合物の可逆阻害用マスキングリガンド Download PDFInfo
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- 2009-12-08 WO PCT/US2009/067119 patent/WO2010077643A1/en not_active Ceased
- 2009-12-08 JP JP2011539791A patent/JP2012511033A/ja active Pending
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- 2009-12-08 EP EP09836702A patent/EP2356131A4/en not_active Withdrawn
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020098195A (ja) * | 2013-01-04 | 2020-06-25 | シトムクス セラピューティクス，インコーポレイティド | 生体系におけるプロテアーゼ活性を検出するための組成物及び方法 |
| JP7001652B2 (ja) | 2013-01-04 | 2022-02-21 | シトムクス セラピューティクス，インコーポレイティド | 生体系におけるプロテアーゼ活性を検出するための組成物及び方法 |
| JP2016520614A (ja) * | 2013-05-28 | 2016-07-14 | ディーシービー−ユーエスエー エルエルシーＤｃｂ−Ｕｓａ Ｌｌｃ | タンパク質薬物の不活性化のための抗体ロッカー |
| JP2022065174A (ja) * | 2013-07-25 | 2022-04-26 | シトムクス セラピューティクス，インコーポレイティド | 多重特異性抗体、多重特異性活性化可能抗体、及びそれらの使用方法 |
| JP2016538240A (ja) * | 2013-09-25 | 2016-12-08 | シトムクス セラピューティクス，インコーポレイティド | マトリックスメタロプロテイナーゼ基質及び他の切断可能部分並びにそれらの使用方法 |
| JP2018509182A (ja) * | 2015-03-13 | 2018-04-05 | サイトメックス セラピューティクス インコーポレイテッド | 抗ｐｄｌ１抗体、活性化可能抗ｐｄｌ１抗体、およびその使用方法 |
| JP2021072807A (ja) * | 2015-03-13 | 2021-05-13 | サイトメックス セラピューティクス インコーポレイテッド | 抗ｐｄｌ１抗体、活性化可能抗ｐｄｌ１抗体、およびその使用方法 |
| US11174316B2 (en) | 2015-03-13 | 2021-11-16 | Cytomx Therapeutics, Inc. | Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of use thereof |
| JP7165217B2 (ja) | 2015-03-13 | 2022-11-02 | サイトメックス セラピューティクス インコーポレイテッド | 抗ｐｄｌ１抗体、活性化可能抗ｐｄｌ１抗体、およびその使用方法 |
| JP2018520642A (ja) * | 2015-05-01 | 2018-08-02 | ジェネンテック， インコーポレイテッド | マスク抗ｃｄ３抗体及びその使用方法 |
| US11168144B2 (en) | 2017-06-01 | 2021-11-09 | Cytomx Therapeutics, Inc. | Activatable anti-PDL1 antibodies, and methods of use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2356131A4 (en) | 2012-09-12 |
| EP2356131A1 (en) | 2011-08-17 |
| WO2010077643A1 (en) | 2010-07-08 |
| US20100189727A1 (en) | 2010-07-29 |
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