JP2012510618A5 - - Google Patents
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- Publication number
- JP2012510618A5 JP2012510618A5 JP2011538701A JP2011538701A JP2012510618A5 JP 2012510618 A5 JP2012510618 A5 JP 2012510618A5 JP 2011538701 A JP2011538701 A JP 2011538701A JP 2011538701 A JP2011538701 A JP 2011538701A JP 2012510618 A5 JP2012510618 A5 JP 2012510618A5
- Authority
- JP
- Japan
- Prior art keywords
- complement
- hla
- biological sample
- antibody
- agi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000295 complement effect Effects 0.000 claims 40
- 238000000034 method Methods 0.000 claims 25
- 239000012472 biological sample Substances 0.000 claims 17
- 239000000427 antigen Substances 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 239000011859 microparticle Substances 0.000 claims 10
- 239000007787 solid Substances 0.000 claims 10
- 239000000758 substrate Substances 0.000 claims 10
- 210000004027 cell Anatomy 0.000 claims 5
- 239000003446 ligand Substances 0.000 claims 5
- 239000011324 bead Substances 0.000 claims 4
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- 210000000265 leukocyte Anatomy 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 229920000936 Agarose Polymers 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 239000004793 Polystyrene Substances 0.000 claims 1
- 239000000370 acceptor Substances 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 239000004816 latex Substances 0.000 claims 1
- 229920000126 latex Polymers 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 229920002223 polystyrene Polymers 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11894908P | 2008-12-01 | 2008-12-01 | |
| US61/118,949 | 2008-12-01 | ||
| PCT/US2009/065984 WO2010065425A1 (en) | 2008-12-01 | 2009-11-25 | Methods and compositions for detection of complement fixing antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014183579A Division JP2015007651A (ja) | 2008-12-01 | 2014-09-09 | 補体固定抗体の検出のための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012510618A JP2012510618A (ja) | 2012-05-10 |
| JP2012510618A5 true JP2012510618A5 (cg-RX-API-DMAC7.html) | 2013-01-17 |
| JP5792626B2 JP5792626B2 (ja) | 2015-10-14 |
Family
ID=42233567
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011538701A Active JP5792626B2 (ja) | 2008-12-01 | 2009-11-25 | 補体固定抗体の検出のための方法および組成物 |
| JP2014183579A Pending JP2015007651A (ja) | 2008-12-01 | 2014-09-09 | 補体固定抗体の検出のための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014183579A Pending JP2015007651A (ja) | 2008-12-01 | 2014-09-09 | 補体固定抗体の検出のための方法および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10338080B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2353005B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5792626B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN102203610A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009322607B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0923199B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2740192C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010065425A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3722320A3 (en) | 2012-10-25 | 2020-12-30 | Bioverativ USA Inc. | Anti-complement c1s antibodies and uses thereof |
| PT2914291T (pt) * | 2012-11-02 | 2022-05-05 | Bioverativ Usa Inc | Anticorpos anti-complemento c1s e suas utilizações |
| US10101337B2 (en) * | 2013-03-14 | 2018-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting donor-specific antibodies and systems for practicing the same |
| US20160041185A1 (en) * | 2013-03-14 | 2016-02-11 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of Detecting Complement Fixing and Non-Complement Fixing Antibodies and Systems for Practicing the Same |
| BR112016000106B1 (pt) | 2013-07-09 | 2023-11-21 | Annexon, Inc. | Anticorpos anti-c1q e usos dos mesmos, célula de hibridoma, composição farmacêutica e métodos de detecção de sinapses em uma amostra biológica referências cruzadas a pedidos relacionados |
| KR102626877B1 (ko) * | 2014-11-05 | 2024-01-19 | 애넥슨, 인코포레이티드 | 인간화 항-보체 인자 c1q 항체 및 이의 용도 |
| HRP20230093T1 (hr) | 2015-04-06 | 2023-03-31 | Bioverativ Usa Inc. | Humanizirana anti-c1s protutijela i postupci njihove primjene |
| US10527613B2 (en) | 2015-11-10 | 2020-01-07 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarker detection methods and systems and kits for practicing same |
| IL296130A (en) | 2015-11-24 | 2022-11-01 | Annexon Inc | Anti-complement factor c1q fab fragments and uses thereof |
| CN108883174B (zh) | 2015-12-03 | 2023-02-14 | Nj共享网络公司 | 用于鉴定可移植的组织样品的IgG亚型测定 |
| EP3239711B1 (en) | 2016-04-27 | 2019-12-25 | JIMRO Co., Ltd. | Method for measuring anti-drug antibody |
| WO2017187656A1 (ja) * | 2016-04-27 | 2017-11-02 | 株式会社Jimro | 抗医薬品抗体の測定方法 |
| CN116554320A (zh) | 2016-10-12 | 2023-08-08 | 美国比奥维拉迪维股份有限公司 | 抗C1s抗体及其使用方法 |
| WO2018140655A2 (en) * | 2017-01-25 | 2018-08-02 | Northeastern University | Electrochemical antibody-based biosensor |
| CN114910633B (zh) * | 2017-10-26 | 2025-04-25 | 科美诊断技术股份有限公司 | 一种免疫复合物及其应用 |
| CN111398580B (zh) * | 2017-11-03 | 2023-06-13 | 科美诊断技术股份有限公司 | 一种检测样本中目标IgM抗体的方法 |
| CN109991405B (zh) * | 2017-12-29 | 2023-01-24 | 上海索昕生物科技有限公司 | 一种免疫检测试剂盒及其应用 |
| JP7153493B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
| JP7153494B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
| EP3965807A4 (en) * | 2019-05-06 | 2023-08-30 | The Regents of the University of California | NON-HLA MARKERS OF TRANSPLANT REJECTION |
| CN111812336A (zh) * | 2020-08-10 | 2020-10-23 | 苏州康和顺医疗技术有限公司 | 用于检测冠状病毒抗体的检测试剂盒及其制备方法 |
| EP4226155A1 (en) * | 2020-10-09 | 2023-08-16 | Takeda Vaccines, Inc. | Methods for determining complement-fixing antibodies |
| WO2022212704A1 (en) * | 2021-03-31 | 2022-10-06 | Takeda Vaccines, Inc. | Methods for characterizing the immune response of a subject to a dengue virus composition |
| EP4089413A1 (en) * | 2021-05-12 | 2022-11-16 | Cisbio Bioassays | Method for determining the binding of an antibody to the complement component 1q (c1q) |
| WO2023114763A1 (en) | 2021-12-13 | 2023-06-22 | Annexon, Inc. | Anti-complement factor c1q antibodies with single binding arms and uses thereof |
| CN118604345A (zh) * | 2024-05-31 | 2024-09-06 | 上海览屹医药科技有限公司 | 酶联免疫方法测定单克隆抗体浓度 |
| CN120142127A (zh) * | 2025-05-16 | 2025-06-13 | 上海荻硕贝肯基因科技有限公司 | 一种供者特异性抗体的检测方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| JPS6184560A (ja) * | 1984-10-02 | 1986-04-30 | Karupisu Shokuhin Kogyo Kk | 補体結合性抗体の測定法 |
| US5035995A (en) * | 1984-10-02 | 1991-07-30 | Calpis Food Industry Co., Ltd. | Test method involving substance-conjugated complement component C1q |
| JPS61245060A (ja) | 1985-04-23 | 1986-10-31 | Takara Shuzo Co Ltd | ヒト補体１ｑ定量用キツト及び定量法 |
| JPS6225994A (ja) * | 1985-05-30 | 1987-02-03 | ジエネテイツク システムズ コ−ポレイシヨン | Ｈｌａタイプ分け用モノクロ−ナル抗体 |
| IL84160A0 (en) * | 1986-10-16 | 1988-03-31 | Vasocor | Method and kit for immune complex assay |
| US5176998A (en) | 1986-12-01 | 1993-01-05 | The Scripps Research Institute | Cell surface antigen detection method |
| US5223397A (en) | 1991-06-05 | 1993-06-29 | Sangstat Medical Corporation | Soluble hla cross-match |
| US5270169A (en) * | 1992-06-23 | 1993-12-14 | Sangstat Medical Corporation | Detection of HLA antigen-containing immune complexes |
| DE69334095T2 (de) | 1992-07-17 | 2007-04-12 | Dana-Farber Cancer Institute, Boston | Verfahren zur intrazellulären Bindung von zielgerichteten Molekülen |
| US5851829A (en) | 1993-07-16 | 1998-12-22 | Dana-Farber Cancer Institute | Method of intracellular binding of target molecules |
| GB9502112D0 (en) | 1995-02-03 | 1995-03-22 | British Biocell Int | Assay device and method |
| US6159748A (en) * | 1995-03-13 | 2000-12-12 | Affinitech, Ltd | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry |
| US5948627A (en) | 1997-05-30 | 1999-09-07 | One Lambda | Immunobead flow cytometric detection of anti-HLA panel-reactive antibody |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| EP1028751B1 (en) | 1997-10-31 | 2008-12-31 | Genentech, Inc. | Methods and compositions comprising glycoprotein glycoforms |
| CN1423130A (zh) * | 2002-04-26 | 2003-06-11 | 帕弗瑞生物技术(北京)有限公司 | 流式测定固定补体抗体的hla交叉配型方法和试剂盒 |
| CN1444044A (zh) * | 2002-06-18 | 2003-09-24 | 帕弗瑞生物技术(北京)有限公司 | 以酶联免疫测定为基础的hla补体依赖性细胞毒性抗体检测方法和试剂盒 |
| TW200508609A (en) | 2003-07-15 | 2005-03-01 | Bioarray Solutions Ltd | Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays |
| US20050277158A1 (en) * | 2004-06-10 | 2005-12-15 | Ge Chen | Method and kit for donor specific complement-fixing antibodies crossmatch |
| US7799556B2 (en) * | 2004-06-17 | 2010-09-21 | George Dacai Liu | System and method for antigen structure-independent detection of antigens captured on antibody arrays |
| AU2006244486A1 (en) * | 2005-05-06 | 2006-11-16 | Platypus Technologies, Llc | Liquid crystal based analyte detection |
| CN100354629C (zh) * | 2005-10-17 | 2007-12-12 | 中国人民解放军第三军医大学第一附属医院 | 用胶体金标记补体第一成分q亚单位做指示剂的蛋白芯片/微阵列检测系统及检测方法 |
| GB0618496D0 (en) * | 2006-09-20 | 2006-11-01 | Common Services Agency | Blood typing |
| JP2008100986A (ja) * | 2006-09-21 | 2008-05-01 | Takahiro Ochi | Ｃ１ｑ結合物質、ならびにその使用 |
| US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
| JP2009080019A (ja) | 2007-09-26 | 2009-04-16 | Nippon Sekijiyuujishiya | 蛍光ビーズを用いた免疫複合体検出による抗体解析法 |
| DE102008045696A1 (de) | 2008-09-04 | 2010-03-11 | Drk Blutspendedienst West Ggmbh | Granulozyten HNA-3a/b-Antigen |
| EP2527473A3 (en) | 2009-05-29 | 2013-03-06 | The Regents of the University of California | B cell signature associated with tolerance in transplant recipients |
| US20120065092A1 (en) | 2010-09-14 | 2012-03-15 | Wai Hobert | Fusion analyte cytometric bead assay, and systems and kits for performing the same |
| WO2013029181A1 (en) | 2011-08-30 | 2013-03-07 | The Governors Of The University Of Alberta | Method and system for abo antibody detection and characterization |
| US20160041185A1 (en) | 2013-03-14 | 2016-02-11 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of Detecting Complement Fixing and Non-Complement Fixing Antibodies and Systems for Practicing the Same |
| US10101337B2 (en) | 2013-03-14 | 2018-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting donor-specific antibodies and systems for practicing the same |
-
2009
- 2009-11-25 US US13/129,554 patent/US10338080B2/en active Active
- 2009-11-25 AU AU2009322607A patent/AU2009322607B2/en active Active
- 2009-11-25 WO PCT/US2009/065984 patent/WO2010065425A1/en not_active Ceased
- 2009-11-25 CN CN2009801446394A patent/CN102203610A/zh active Pending
- 2009-11-25 CA CA2740192A patent/CA2740192C/en active Active
- 2009-11-25 CN CN201610218019.2A patent/CN105866426B/zh active Active
- 2009-11-25 EP EP09830911.5A patent/EP2353005B1/en active Active
- 2009-11-25 JP JP2011538701A patent/JP5792626B2/ja active Active
- 2009-11-25 BR BRPI0923199A patent/BRPI0923199B8/pt not_active IP Right Cessation
- 2009-11-25 EP EP18190547.2A patent/EP3460480B1/en active Active
-
2014
- 2014-09-09 JP JP2014183579A patent/JP2015007651A/ja active Pending
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