JP2012509922A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012509922A5 JP2012509922A5 JP2011537951A JP2011537951A JP2012509922A5 JP 2012509922 A5 JP2012509922 A5 JP 2012509922A5 JP 2011537951 A JP2011537951 A JP 2011537951A JP 2011537951 A JP2011537951 A JP 2011537951A JP 2012509922 A5 JP2012509922 A5 JP 2012509922A5
- Authority
- JP
- Japan
- Prior art keywords
- forming agent
- dry gas
- matrix
- spray
- active substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 239000000843 powder Substances 0.000 claims 8
- 239000013543 active substance Substances 0.000 claims 7
- 239000011159 matrix material Substances 0.000 claims 6
- 238000001035 drying Methods 0.000 claims 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 3
- 229930195725 Mannitol Natural products 0.000 claims 3
- 235000010355 mannitol Nutrition 0.000 claims 3
- 239000000594 mannitol Substances 0.000 claims 3
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 claims 2
- 230000003454 betamimetic effect Effects 0.000 claims 2
- 239000000812 cholinergic antagonist Substances 0.000 claims 2
- 229940121647 egfr inhibitor Drugs 0.000 claims 2
- 229940043355 kinase inhibitor Drugs 0.000 claims 2
- 239000003595 mist Substances 0.000 claims 2
- 239000003757 phosphotransferase inhibitor Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 150000003431 steroids Chemical class 0.000 claims 2
- 150000005846 sugar alcohols Polymers 0.000 claims 2
- 102000015636 Oligopeptides Human genes 0.000 claims 1
- 108010038807 Oligopeptides Proteins 0.000 claims 1
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 230000003266 anti-allergic effect Effects 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 239000003125 aqueous solvent Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000007796 conventional method Methods 0.000 claims 1
- 239000003136 dopamine receptor stimulating agent Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 claims 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000005507 spraying Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 239000003848 thrombocyte activating factor antagonist Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08170072 | 2008-11-27 | ||
| EP08170072.6 | 2008-11-27 | ||
| PCT/EP2009/065621 WO2010060875A1 (de) | 2008-11-27 | 2009-11-23 | Neue pulverförmige kristalline arzneimittel zur inhalation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509922A JP2012509922A (ja) | 2012-04-26 |
| JP2012509922A5 true JP2012509922A5 (enExample) | 2013-01-17 |
Family
ID=40568782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537951A Pending JP2012509922A (ja) | 2008-11-27 | 2009-11-23 | 新規粉末化結晶質吸入薬 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20120135969A1 (enExample) |
| EP (1) | EP2370053A1 (enExample) |
| JP (1) | JP2012509922A (enExample) |
| CA (1) | CA2744655A1 (enExample) |
| WO (1) | WO2010060875A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201113662D0 (en) * | 2011-08-08 | 2011-09-21 | Prosonix Ltd | Pharmaceutical compositions |
| EP2705838A1 (en) * | 2012-09-06 | 2014-03-12 | Xspray Microparticles Ab | Tiotropium preparations |
| BR112015010601B1 (pt) * | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | Composição farmacêutica e uso da composição |
| WO2014165303A1 (en) | 2013-04-01 | 2014-10-09 | Pulmatrix, Inc. | Tiotropium dry powders |
| PT107568B (pt) * | 2014-03-31 | 2018-11-05 | Hovione Farm S A | Processo de secagem por atomização para a produção de pós com propriedades melhoradas. |
| GB201609940D0 (en) | 2016-06-07 | 2016-07-20 | Novabiotics Ltd | Microparticles |
| EP3478265B1 (en) * | 2016-06-30 | 2025-01-01 | Philip Morris Products S.A. | Nicotine particles |
| CA3116637A1 (en) | 2018-10-17 | 2020-04-23 | Novabiotics Limited | Dosage regime |
| KR20230061365A (ko) * | 2020-09-03 | 2023-05-08 | 필립모리스 프로덕츠 에스.에이. | 분무 건조 저 흡습성 활성 분말 조성물 |
| PL4208152T3 (pl) * | 2020-09-03 | 2025-09-22 | Philip Morris Products S.A. | Nisko higroskopijne aktywne kompozycje proszku |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58177101A (ja) * | 1982-04-09 | 1983-10-17 | Lion Corp | 熱風噴霧乾燥方法 |
| JP2587059B2 (ja) * | 1987-07-06 | 1997-03-05 | 大川原化工機株式会社 | 流動層内蔵型噴霧乾燥装置 |
| SE9302777D0 (sv) * | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
| US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| JPH0663301A (ja) * | 1992-08-19 | 1994-03-08 | Kao Corp | 噴霧乾燥方法及び噴霧乾燥装置 |
| WO1995031479A1 (en) * | 1994-05-18 | 1995-11-23 | Inhale Therapeutic Systems, Inc. | Methods and compositions for the dry powder formulation of interferons |
| WO1999055362A1 (en) * | 1998-04-29 | 1999-11-04 | Genentech, Inc. | Spray dried formulations of igf-i |
| CA2347856C (en) * | 1998-11-13 | 2009-02-17 | Jagotec Ag | Dry powder for inhalation |
| US20030018019A1 (en) * | 2001-06-23 | 2003-01-23 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics |
| CA2500065A1 (en) * | 2002-09-30 | 2004-04-15 | Acusphere, Inc. | Sustained release porous microparticles for inhalation |
| DE10339197A1 (de) * | 2003-08-22 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Sprühgetrocknete amorphe Pulver mit geringer Restfeuchte und guter Lagerstabilität |
| ES2523518T3 (es) * | 2004-04-22 | 2014-11-26 | Boehringer Ingelheim International Gmbh | Nuevas combinaciones farmacológicas para el tratamiento de enfermedades de las vías respiratorias |
| DE102004022926A1 (de) * | 2004-05-10 | 2005-12-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Sprühgetrocknete Pulver enthaltend zumindest ein 1,4 O-verknüpftes Saccharose-Derivat und Verfahren zu deren Herstellung |
-
2009
- 2009-11-23 CA CA2744655A patent/CA2744655A1/en not_active Abandoned
- 2009-11-23 WO PCT/EP2009/065621 patent/WO2010060875A1/de not_active Ceased
- 2009-11-23 US US13/131,386 patent/US20120135969A1/en not_active Abandoned
- 2009-11-23 JP JP2011537951A patent/JP2012509922A/ja active Pending
- 2009-11-23 EP EP09756312A patent/EP2370053A1/de not_active Withdrawn
-
2015
- 2015-04-02 US US14/676,872 patent/US20150258030A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012509922A5 (enExample) | ||
| Kou et al. | Physico-chemical aspects of lactose for inhalation | |
| AU2025204271A1 (en) | Microcrystalline diketopiperazine compositions and methods | |
| WO2005079755A3 (en) | Interleukin-13 antagonist powders, spray-dried particles, and methods | |
| KR102523677B1 (ko) | 니코틴 입자 및 조성물 | |
| HRP20210704T1 (hr) | Formulacija suhog praška koja sadrži antikolinergik, kortikosteroid i beta-adrenergik za davanje inhalacijom | |
| CN105828819A (zh) | 烟碱制剂及其制备方法 | |
| RU2014140539A (ru) | Агрегированные частицы | |
| RU2608713C3 (ru) | Новая доза и препаративная форма | |
| JP2016534153A5 (enExample) | ||
| JP2014515356A5 (enExample) | ||
| JP2017532374A5 (enExample) | ||
| EA201591729A1 (ru) | Пригодные для вдыхания агломераты частиц пористого носителя и тонкоизмельченного лекарственного средства | |
| JP2018528966A5 (enExample) | ||
| JP2015519356A5 (enExample) | ||
| RU2011117256A (ru) | Вдыхаемые частицы, содержащие тиотропий | |
| JP2014224147A5 (enExample) | ||
| RU2018120519A (ru) | Фармацевтические композиции рибавирина | |
| RU2018112077A (ru) | Направленная доставка высушенных распылением композиций в легкие | |
| EP2682108A3 (en) | Dry Powder Inhalers Comprising a Carrier Other Than Lactose and a Ternary Component | |
| HRP20211598T1 (hr) | Postupak priprave formulacije suhog praška koji sadrži antikolinergik, kortikosteroid i beta-adrenergik | |
| KR20180003572A (ko) | 다중 약물 취성 매트릭스 조성물 | |
| HRP20211599T1 (hr) | Postupak priprave formulacije suhog praška koji sadrži antikolinergik, kortikosteroid i beta-adrenergik | |
| EP2682097A3 (en) | Dry Powder Inhalers Comprising A Carrier Other Than Lactose | |
| RU2015143927A (ru) | Деаморфизация высушенных распылением составов посредством смешивания распылением |