JP2012509922A5 - - Google Patents
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- Publication number
- JP2012509922A5 JP2012509922A5 JP2011537951A JP2011537951A JP2012509922A5 JP 2012509922 A5 JP2012509922 A5 JP 2012509922A5 JP 2011537951 A JP2011537951 A JP 2011537951A JP 2011537951 A JP2011537951 A JP 2011537951A JP 2012509922 A5 JP2012509922 A5 JP 2012509922A5
- Authority
- JP
- Japan
- Prior art keywords
- forming agent
- dry gas
- matrix
- spray
- active substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 239000000843 powder Substances 0.000 claims 8
- 239000013543 active substance Substances 0.000 claims 7
- 239000011159 matrix material Substances 0.000 claims 6
- 238000001035 drying Methods 0.000 claims 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 3
- 229930195725 Mannitol Natural products 0.000 claims 3
- 235000010355 mannitol Nutrition 0.000 claims 3
- 239000000594 mannitol Substances 0.000 claims 3
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 claims 2
- 230000003454 betamimetic effect Effects 0.000 claims 2
- 239000000812 cholinergic antagonist Substances 0.000 claims 2
- 229940121647 egfr inhibitor Drugs 0.000 claims 2
- 229940043355 kinase inhibitor Drugs 0.000 claims 2
- 239000003595 mist Substances 0.000 claims 2
- 239000003757 phosphotransferase inhibitor Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 150000003431 steroids Chemical class 0.000 claims 2
- 150000005846 sugar alcohols Polymers 0.000 claims 2
- 102000015636 Oligopeptides Human genes 0.000 claims 1
- 108010038807 Oligopeptides Proteins 0.000 claims 1
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 230000003266 anti-allergic effect Effects 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 239000003125 aqueous solvent Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000007796 conventional method Methods 0.000 claims 1
- 239000003136 dopamine receptor stimulating agent Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 claims 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000005507 spraying Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 239000003848 thrombocyte activating factor antagonist Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08170072.6 | 2008-11-27 | ||
| EP08170072 | 2008-11-27 | ||
| PCT/EP2009/065621 WO2010060875A1 (de) | 2008-11-27 | 2009-11-23 | Neue pulverförmige kristalline arzneimittel zur inhalation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509922A JP2012509922A (ja) | 2012-04-26 |
| JP2012509922A5 true JP2012509922A5 (enExample) | 2013-01-17 |
Family
ID=40568782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537951A Pending JP2012509922A (ja) | 2008-11-27 | 2009-11-23 | 新規粉末化結晶質吸入薬 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20120135969A1 (enExample) |
| EP (1) | EP2370053A1 (enExample) |
| JP (1) | JP2012509922A (enExample) |
| CA (1) | CA2744655A1 (enExample) |
| WO (1) | WO2010060875A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201113662D0 (en) * | 2011-08-08 | 2011-09-21 | Prosonix Ltd | Pharmaceutical compositions |
| EP2705838A1 (en) * | 2012-09-06 | 2014-03-12 | Xspray Microparticles Ab | Tiotropium preparations |
| BR112015010601B1 (pt) * | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | Composição farmacêutica e uso da composição |
| KR20150135328A (ko) | 2013-04-01 | 2015-12-02 | 풀매트릭스 인코퍼레이티드 | 티오트로피움 건조 분말 |
| PT107568B (pt) | 2014-03-31 | 2018-11-05 | Hovione Farm S A | Processo de secagem por atomização para a produção de pós com propriedades melhoradas. |
| GB201609940D0 (en) | 2016-06-07 | 2016-07-20 | Novabiotics Ltd | Microparticles |
| CA3023626A1 (en) * | 2016-06-30 | 2018-01-04 | Philip Morris Products S.A. | Nicotine particles |
| EP3866775B1 (en) | 2018-10-17 | 2025-03-19 | Novabiotics Limited | Cysteamine for use in the treatment of lung diseases |
| JP2023540190A (ja) * | 2020-09-03 | 2023-09-22 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 低吸湿性活性粉末組成物 |
| US20230346696A1 (en) * | 2020-09-03 | 2023-11-02 | Philip Morris Products S.A. | Spray dried low hygroscopicity active powder compositions |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58177101A (ja) * | 1982-04-09 | 1983-10-17 | Lion Corp | 熱風噴霧乾燥方法 |
| JP2587059B2 (ja) * | 1987-07-06 | 1997-03-05 | 大川原化工機株式会社 | 流動層内蔵型噴霧乾燥装置 |
| SE9302777D0 (sv) * | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
| US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| JPH0663301A (ja) * | 1992-08-19 | 1994-03-08 | Kao Corp | 噴霧乾燥方法及び噴霧乾燥装置 |
| AU696387B2 (en) * | 1994-05-18 | 1998-09-10 | Inhale Therapeutic Systems, Inc. | Methods and compositions for the dry powder formulation of interferons |
| AU3764199A (en) * | 1998-04-29 | 1999-11-16 | Genentech Inc. | Spray dried formulations of igf-i |
| CN1150895C (zh) * | 1998-11-13 | 2004-05-26 | 杰格研究股份公司 | 用于吸入给药的干粉 |
| US20030018019A1 (en) * | 2001-06-23 | 2003-01-23 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics |
| CN1694689A (zh) * | 2002-09-30 | 2005-11-09 | 阿库斯菲尔公司 | 供吸入的缓释多孔微粒 |
| DE10339197A1 (de) * | 2003-08-22 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Sprühgetrocknete amorphe Pulver mit geringer Restfeuchte und guter Lagerstabilität |
| EP1781298B1 (de) * | 2004-04-22 | 2012-01-04 | Boehringer Ingelheim International GmbH | Arzneinmittelkombinationen enthaltend benzoxazine zur behandlung von atemwegserkrankungen |
| DE102004022926A1 (de) * | 2004-05-10 | 2005-12-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Sprühgetrocknete Pulver enthaltend zumindest ein 1,4 O-verknüpftes Saccharose-Derivat und Verfahren zu deren Herstellung |
-
2009
- 2009-11-23 WO PCT/EP2009/065621 patent/WO2010060875A1/de not_active Ceased
- 2009-11-23 US US13/131,386 patent/US20120135969A1/en not_active Abandoned
- 2009-11-23 CA CA2744655A patent/CA2744655A1/en not_active Abandoned
- 2009-11-23 EP EP09756312A patent/EP2370053A1/de not_active Withdrawn
- 2009-11-23 JP JP2011537951A patent/JP2012509922A/ja active Pending
-
2015
- 2015-04-02 US US14/676,872 patent/US20150258030A1/en not_active Abandoned
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