JP2012509477A5 - - Google Patents
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- Publication number
- JP2012509477A5 JP2012509477A5 JP2011537003A JP2011537003A JP2012509477A5 JP 2012509477 A5 JP2012509477 A5 JP 2012509477A5 JP 2011537003 A JP2011537003 A JP 2011537003A JP 2011537003 A JP2011537003 A JP 2011537003A JP 2012509477 A5 JP2012509477 A5 JP 2012509477A5
- Authority
- JP
- Japan
- Prior art keywords
- ngal
- protein
- antibody
- individual
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004965 antibodies Human genes 0.000 claims 21
- 108090001123 antibodies Proteins 0.000 claims 21
- 102000013519 Lipocalin-2 Human genes 0.000 claims 19
- 108010051335 Lipocalin-2 Proteins 0.000 claims 19
- 208000009304 Acute Kidney Injury Diseases 0.000 claims 4
- 210000001124 Body Fluids Anatomy 0.000 claims 4
- 210000000440 Neutrophils Anatomy 0.000 claims 4
- 206010038436 Renal failure acute Diseases 0.000 claims 4
- 239000010839 body fluid Substances 0.000 claims 3
- 230000000536 complexating Effects 0.000 claims 3
- 230000001809 detectable Effects 0.000 claims 3
- 238000002965 ELISA Methods 0.000 claims 2
- 102000013382 Gelatinases Human genes 0.000 claims 2
- 108010026132 Gelatinases Proteins 0.000 claims 2
- 210000003734 Kidney Anatomy 0.000 claims 2
- 102000019298 Lipocalins Human genes 0.000 claims 2
- 108050006654 Lipocalins Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 210000002700 Urine Anatomy 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11671308P | 2008-11-21 | 2008-11-21 | |
| US61/116,713 | 2008-11-21 | ||
| PCT/IB2009/055299 WO2010058378A1 (en) | 2008-11-21 | 2009-11-23 | Methods, devices and kits for detecting or monitoring acute kidney injury |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012509477A JP2012509477A (ja) | 2012-04-19 |
| JP2012509477A5 true JP2012509477A5 (US07794700-20100914-C00194.png) | 2012-12-13 |
| JP5438770B2 JP5438770B2 (ja) | 2014-03-12 |
Family
ID=41611201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537003A Expired - Fee Related JP5438770B2 (ja) | 2008-11-21 | 2009-11-23 | 急性腎臓損傷を検出またはモニターするための方法、装置およびキット |
Country Status (12)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2035835B1 (en) | 2006-05-30 | 2011-12-28 | Antibodyshop A/S | Methods for rapid assessment of severity of a trauma |
| US8313919B2 (en) | 2007-03-21 | 2012-11-20 | Bioporto Diagnostics A/S | Diagnostic test for renal injury |
| US8846036B2 (en) | 2007-10-19 | 2014-09-30 | Abbott Laboratories | Antibodies that bind to mammalian NGAL and uses thereof |
| JP2012508177A (ja) * | 2008-11-05 | 2012-04-05 | アボット・ラボラトリーズ | 尿および組換えチャイニーズハムスター卵巣（ｃｈｏ）細胞から濃縮された好中球ゼラチナーゼ関連リポカリン（ｎｇａｌ）タンパク質アイソフォーム、ならびに関連する組成物、抗体、ならびに濃縮、分析および使用の方法 |
| EP2568291A1 (en) * | 2011-09-07 | 2013-03-13 | Roche Diagnostics GmbH | L-FABP based diagnosis of kidney injury after an acute event or after a surgical intervention |
| BR112014006741A2 (pt) * | 2011-09-22 | 2017-03-28 | Univ Los Andes | método para monitorização, diagnóstico e/ou prognóstico de lesão renal aguda no estágio inicial |
| CA2886779C (en) * | 2012-10-02 | 2022-11-01 | Sphingotec Gmbh | A method for diagnosing or monitoring kidney function or diagnosing kidney dysfunction |
| CN102928606B (zh) * | 2012-11-16 | 2015-10-07 | 武汉明德生物科技股份有限公司 | 多抗体标记的降钙素原快速检测试剂盒 |
| BR112015014232A2 (pt) * | 2012-12-20 | 2017-07-11 | Novartis Ag | lesão renal aguda |
| US9488663B2 (en) | 2013-03-14 | 2016-11-08 | Abbott Point Of Care Inc. | Electrochemical methods and devices for amending urine samples for immunosensor detection |
| US9651547B2 (en) | 2013-03-14 | 2017-05-16 | Abbott Point Of Care Inc. | Electrochemical methods and devices for amending urine samples for immunosensor detection |
| AU2014232782B2 (en) | 2013-03-15 | 2018-05-24 | Hycor Biomedical, Inc. | Device and associated methods for performing luminescence and fluorescence measurements of a sample |
| RU2566709C2 (ru) * | 2013-12-16 | 2015-10-27 | Владимир Борисович Бородулин | Способ ранней диагностики хронической болезни почек |
| CN107003320B (zh) * | 2014-11-25 | 2021-08-17 | 豪夫迈·罗氏有限公司 | 慢性肾脏疾病的快速进展的生物标志物 |
| CN104479015A (zh) * | 2014-12-04 | 2015-04-01 | 东南大学 | 针对ngal表位的纳米抗体及其应用 |
| CN105911274A (zh) * | 2016-06-12 | 2016-08-31 | 吉林大学 | 一种同步定量检测不同分子形式人中性粒细胞脂质运载蛋白免疫层析装置及其制备方法 |
| CN108802402A (zh) * | 2018-06-15 | 2018-11-13 | 重庆大学 | 一种快速鉴别呼吸道感染类型的试剂盒及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9401351D0 (sv) | 1994-04-21 | 1994-04-21 | Venge | A method for diagnosis |
| AU1169702A (en) * | 2000-10-13 | 2002-04-22 | Childrens Medical Center | Non-invasive enzyme screen for tissue remodelling-associated conditions |
| US7056702B2 (en) * | 2002-12-16 | 2006-06-06 | Kimberly Clark Co | Detecting lipocalin |
| CN1791797A (zh) * | 2003-03-27 | 2006-06-21 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
| WO2004088276A2 (en) | 2003-03-27 | 2004-10-14 | Children's Hospital Medical Center | A method and kit for detecting the early onset of renal tubular cell injury |
| US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
| CA2565701A1 (en) * | 2004-05-06 | 2005-11-17 | Jonathan M. Barasch | Ngal for reduction and amelioration of ischemic and nephrotoxic injuries |
| CN101010001A (zh) * | 2004-05-06 | 2007-08-01 | 哥伦比亚大学受托人 | Ngal用于减少和改善局部缺血和肾中毒损伤 |
| DK2128625T3 (en) | 2004-12-20 | 2017-05-01 | Antibodyshop As | Determination of neutrophil gelatinase-associated lipocalin (NGAL) as a diagnostic marker for renal disorders |
| US20070037232A1 (en) | 2005-03-31 | 2007-02-15 | Barasch Jonathan M | Detection of NGAL in chronic renal disease |
| US20080090304A1 (en) | 2006-10-13 | 2008-04-17 | Barasch Jonathan Matthew | Diagnosis and monitoring of chronic renal disease using ngal |
| JP2009527735A (ja) * | 2006-02-17 | 2009-07-30 | チルドレンズ メディカル センター コーポレーション | 癌に対するバイオマーカーとしての遊離ｎｇａｌ |
| EP2235053A1 (en) * | 2007-10-19 | 2010-10-06 | Abbott Laboratories | Glycosylated mammalian ngal and use thereof |
| US20090123970A1 (en) * | 2007-10-19 | 2009-05-14 | Abbott Laboratories | Glycosylated mammalian ngal and use thereof |
| US20100304413A1 (en) * | 2007-11-15 | 2010-12-02 | Lars Otto Uttenthal | Diagnostic use of individual molecular forms of a biomarker |
-
2009
- 2009-11-23 AU AU2009318813A patent/AU2009318813B2/en not_active Ceased
- 2009-11-23 CA CA2744434A patent/CA2744434C/en active Active
- 2009-11-23 MY MYPI2011002257A patent/MY162697A/en unknown
- 2009-11-23 CN CN200980155194.XA patent/CN102292637B/zh not_active Expired - Fee Related
- 2009-11-23 KR KR1020117014191A patent/KR101939964B1/ko active IP Right Grant
- 2009-11-23 KR KR1020197001145A patent/KR20190006614A/ko not_active Application Discontinuation
- 2009-11-23 WO PCT/IB2009/055299 patent/WO2010058378A1/en active Application Filing
- 2009-11-23 EP EP20090761023 patent/EP2362943A1/en not_active Ceased
- 2009-11-23 JP JP2011537003A patent/JP5438770B2/ja not_active Expired - Fee Related
- 2009-11-23 ES ES16191697T patent/ES2718731T3/es active Active
- 2009-11-23 EP EP16191697.8A patent/EP3141904B1/en not_active Not-in-force
- 2009-11-23 US US13/130,456 patent/US9476880B2/en active Active
- 2009-11-23 RU RU2011125320/15A patent/RU2519722C2/ru active
-
2011
- 2011-05-19 IL IL212988A patent/IL212988A/en active IP Right Grant
