JP2012508892A - 妊娠検査具 - Google Patents
妊娠検査具 Download PDFInfo
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- JP2012508892A JP2012508892A JP2011543820A JP2011543820A JP2012508892A JP 2012508892 A JP2012508892 A JP 2012508892A JP 2011543820 A JP2011543820 A JP 2011543820A JP 2011543820 A JP2011543820 A JP 2011543820A JP 2012508892 A JP2012508892 A JP 2012508892A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/5752—Placental lactogen; Chorionic Somatomammotropin
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
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- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Abstract
【選択図】図1
Description
本開示は、女性の体液サンプル中のヒト胎盤性ラクトゲン(hPL)又はそれに関するフラグメントの濃度の確立に基づき、女性のおよその妊娠段階(妊娠期間)を確立するための方法及び器具に関する。本開示はまた、妊娠段階を特定するための抗−hPL抗体の使用に関するものである。
Claims (13)
- 妊娠段階を決定する方法であって、血液、血漿、血清、及び/又は尿サンプルから選択される女性から採取される体液サンプル中のホルモンhPL又はそのフラグメントの量を定量化するステップと、これに対応する妊娠の段階を確立するステップと、を具えることを特徴とする方法。
- さらに、第二のホルモンの量を定量化するステップを具えることを特徴とする請求項1に記載の方法。
- 前記第二のホルモンが、hCG、非抱合型エストラジオール、リラキシン、又はこれらの組み合わせから選択されることを特徴とする請求項2に記載の方法。
- 前記定量化が、各ホルモンに特異的な一又はそれ以上の抗体を用いて、一又は複数のホルモンの存在を検出することを用いることを特徴とする請求項1乃至3のいずれか1項に記載の方法。
- 妊娠段階を確立するために女性から採取される、血液、血漿、血清、及び/又は尿サンプルから選択される体液サンプル中のhPL又はそのフラグメントのレベル/量を検出するのに適することを特徴とする器具。
- 前記器具が、尿サンプル中のhPLのレベル/量を検出するのに適することを特徴とする請求項5に記載の器具。
- 前記器具が、サンプルの分析結果を提示するためのディスプレイを具えることを特徴とする請求項5又は6に記載の器具。
- 前記ディスプレイが、デジタルであることを特徴とする請求項7に記載の器具。
- 妊娠段階を確立するために、女性から採取される体液サンプル中のhPLの濃度を検査するための器具及び/又は試薬を具えることを特徴とするキット。
- 血液、血漿、血清及び/又は尿サンプルから選択されるサンプル中のhPLの量を分析する器具と、サンプル中のhCGの量を分析する器具とを具えることを特徴とする請求項9に記載のキット。
- 妊娠段階を決定するための抗hPL抗体の使用。
- 前記抗hPL抗体が、モノクローナルであることを特徴とする請求項11に記載の使用。
- 前記抗hPL抗体が、抗−hCG、抗−リラキシン及び/又は抗−非抱合型エストラジオールから選択される抗体と組み合わせて用いられることを特徴とする請求項11又は12に記載の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0820999.1A GB0820999D0 (en) | 2008-11-17 | 2008-11-17 | Pregnancy testing |
GB0820999.1 | 2008-11-17 | ||
PCT/GB2009/051548 WO2010055355A1 (en) | 2008-11-17 | 2009-11-16 | Pregnancy testing |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2012508892A true JP2012508892A (ja) | 2012-04-12 |
JP5911092B2 JP5911092B2 (ja) | 2016-04-27 |
Family
ID=40194755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011543820A Active JP5911092B2 (ja) | 2008-11-17 | 2009-11-16 | 妊娠検査具 |
Country Status (9)
Country | Link |
---|---|
US (2) | US20110287434A1 (ja) |
EP (2) | EP2356464B1 (ja) |
JP (1) | JP5911092B2 (ja) |
CN (1) | CN102272604B (ja) |
BR (1) | BRPI0916101B1 (ja) |
DK (1) | DK2930516T3 (ja) |
ES (2) | ES2699586T3 (ja) |
GB (1) | GB0820999D0 (ja) |
WO (1) | WO2010055355A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016532077A (ja) * | 2013-10-02 | 2016-10-13 | エス・ピー・デイー・スイス・プレシジヨン・ダイアグノステイクス・ゲー・エム・ベー・ハー | 改善された妊娠検査デバイスおよび方法 |
JP2017198533A (ja) * | 2016-04-27 | 2017-11-02 | 大日本印刷株式会社 | センサー装置 |
JP2018536876A (ja) * | 2015-11-09 | 2018-12-13 | ノヴァメッド リミティッド | 体液の採取診断装置 |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102253222B (zh) * | 2011-04-21 | 2014-07-16 | 中国农业科学院农业质量标准与检测技术研究所 | 检测雌激素的方法及其专用试纸 |
CN103163305B (zh) * | 2011-12-19 | 2014-11-12 | 天津中新科炬生物制药有限公司 | 一种快速判断女性妊娠情况的方法 |
US10794920B2 (en) | 2015-04-02 | 2020-10-06 | Spd Swiss Precision Diagnostics Gmbh | Pregnancy test device and method |
CN115728482A (zh) * | 2015-04-06 | 2023-03-03 | Blu诊断有限公司 | 用于检测唾液样品中的分析物的检测装置及使用方法 |
GB201712811D0 (en) * | 2017-08-10 | 2017-09-27 | Spd Swiss Prec Diagnostics Gmbh | System and method for changing a state of a device |
CN108519489A (zh) * | 2018-03-26 | 2018-09-11 | 南通伊仕生物技术股份有限公司 | 一种电子检测笔及早孕孕周数检测方法 |
CN111596076B (zh) * | 2020-06-04 | 2023-05-02 | 昆明天沃生物科技有限公司 | 一种检测羊生育能力的方法 |
WO2022125710A1 (en) | 2020-12-09 | 2022-06-16 | GHP Solutions, LLC | Methods of detecting papp-a and related methods for gestational age assessment |
Citations (2)
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JPH06258325A (ja) * | 1980-07-28 | 1994-09-16 | Akzo Nv | 異なる2又は3種類のモノクローナル抗体を使用する 抗原測定法及び該モノクローナル抗体を利用した試験 キット |
EP1866652A1 (en) * | 2005-03-24 | 2007-12-19 | Inverness Medical Switzerland GmbH | Determining the estimated date of embryo implantation and related dates |
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US3892841A (en) | 1973-07-11 | 1975-07-01 | American Cyanamid Co | Enhancing the visibility of immunodiffusion precipitin bands in human placental lactogen test |
IT1114861B (it) | 1977-05-12 | 1986-01-27 | Sclavo Inst Sieroterapeut | Metodo per la determinazione del contenuto di costituenti di fluidi biologici e mezzi adatti allo scopo |
JPH0647708B2 (ja) | 1985-07-31 | 1994-06-22 | 大同特殊鋼株式会社 | オ−ステナイト系快削ステンレス鋼 |
JPH0746107B2 (ja) | 1987-04-27 | 1995-05-17 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 検定法 |
CA1337394C (en) * | 1987-11-17 | 1995-10-24 | Nelson N. H. Teng | Vaginal sample test and reagents |
ES2145034T3 (es) | 1993-11-12 | 2000-07-01 | Unilever Nv | Dispositivos analiticos y procedimientos para el uso de los mismos. |
ATE157171T1 (de) | 1993-11-12 | 1997-09-15 | Unipath Ltd | Nachweis vorrichtung und herstellungsverfahren dafür |
GB9419267D0 (en) | 1994-09-23 | 1994-11-09 | Unilever Plc | Assay devices |
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CN1147729C (zh) * | 1998-12-30 | 2004-04-28 | 卢氏实验公司 | 半定量金标免疫层析测试条及诊断盒 |
CN1111283C (zh) * | 1999-09-24 | 2003-06-11 | 吉林省计划生育科学技术研究所 | 人胎盘泌乳素诊断血球免疫扩散板的制备方法 |
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2008
- 2008-11-17 GB GBGB0820999.1A patent/GB0820999D0/en not_active Ceased
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2009
- 2009-11-16 JP JP2011543820A patent/JP5911092B2/ja active Active
- 2009-11-16 EP EP09775256.2A patent/EP2356464B1/en not_active Not-in-force
- 2009-11-16 US US13/129,732 patent/US20110287434A1/en not_active Abandoned
- 2009-11-16 EP EP15164490.3A patent/EP2930516B1/en not_active Not-in-force
- 2009-11-16 ES ES15164490T patent/ES2699586T3/es active Active
- 2009-11-16 WO PCT/GB2009/051548 patent/WO2010055355A1/en active Application Filing
- 2009-11-16 DK DK15164490.3T patent/DK2930516T3/da active
- 2009-11-16 ES ES09775256.2T patent/ES2543001T3/es active Active
- 2009-11-16 BR BRPI0916101A patent/BRPI0916101B1/pt not_active IP Right Cessation
- 2009-11-16 CN CN200980153805.7A patent/CN102272604B/zh not_active Expired - Fee Related
-
2014
- 2014-03-07 US US14/201,601 patent/US10203340B2/en not_active Expired - Fee Related
Patent Citations (2)
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JPH06258325A (ja) * | 1980-07-28 | 1994-09-16 | Akzo Nv | 異なる2又は3種類のモノクローナル抗体を使用する 抗原測定法及び該モノクローナル抗体を利用した試験 キット |
EP1866652A1 (en) * | 2005-03-24 | 2007-12-19 | Inverness Medical Switzerland GmbH | Determining the estimated date of embryo implantation and related dates |
Non-Patent Citations (5)
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016532077A (ja) * | 2013-10-02 | 2016-10-13 | エス・ピー・デイー・スイス・プレシジヨン・ダイアグノステイクス・ゲー・エム・ベー・ハー | 改善された妊娠検査デバイスおよび方法 |
JP2019023647A (ja) * | 2013-10-02 | 2019-02-14 | エス・ピー・デイー・スイス・プレシジヨン・ダイアグノステイクス・ゲー・エム・ベー・ハー | 改善された妊娠検査デバイスおよび方法 |
JP2018536876A (ja) * | 2015-11-09 | 2018-12-13 | ノヴァメッド リミティッド | 体液の採取診断装置 |
JP6994679B2 (ja) | 2015-11-09 | 2022-01-14 | ノヴァメッド リミティッド | 体液の採取診断装置 |
JP2017198533A (ja) * | 2016-04-27 | 2017-11-02 | 大日本印刷株式会社 | センサー装置 |
Also Published As
Publication number | Publication date |
---|---|
DK2930516T3 (da) | 2019-01-02 |
JP5911092B2 (ja) | 2016-04-27 |
BRPI0916101B1 (pt) | 2018-11-13 |
ES2699586T3 (es) | 2019-02-11 |
CN102272604A (zh) | 2011-12-07 |
EP2930516A1 (en) | 2015-10-14 |
ES2543001T3 (es) | 2015-08-13 |
US20110287434A1 (en) | 2011-11-24 |
EP2356464A1 (en) | 2011-08-17 |
GB0820999D0 (en) | 2008-12-24 |
WO2010055355A1 (en) | 2010-05-20 |
US10203340B2 (en) | 2019-02-12 |
CN102272604B (zh) | 2015-08-19 |
US20140273028A1 (en) | 2014-09-18 |
EP2930516B1 (en) | 2018-08-29 |
EP2356464B1 (en) | 2015-04-22 |
BRPI0916101A2 (pt) | 2016-09-27 |
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