JP2012508744A5 - - Google Patents
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- JP2012508744A5 JP2012508744A5 JP2011536414A JP2011536414A JP2012508744A5 JP 2012508744 A5 JP2012508744 A5 JP 2012508744A5 JP 2011536414 A JP2011536414 A JP 2011536414A JP 2011536414 A JP2011536414 A JP 2011536414A JP 2012508744 A5 JP2012508744 A5 JP 2012508744A5
- Authority
- JP
- Japan
- Prior art keywords
- less
- suspension
- particles
- protein
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11508008P | 2008-11-16 | 2008-11-16 | |
| US61/115,080 | 2008-11-16 | ||
| PCT/US2009/063852 WO2010056657A2 (en) | 2008-11-16 | 2009-11-10 | Low viscosity highly concentrated suspensions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014247793A Division JP2015083582A (ja) | 2008-11-16 | 2014-12-08 | 高濃度の低粘度懸濁液 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012508744A JP2012508744A (ja) | 2012-04-12 |
| JP2012508744A5 true JP2012508744A5 (cg-RX-API-DMAC7.html) | 2013-02-21 |
| JP5711138B2 JP5711138B2 (ja) | 2015-04-30 |
Family
ID=42170660
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Expired - Fee Related JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
| JP2014247793A Pending JP2015083582A (ja) | 2008-11-16 | 2014-12-08 | 高濃度の低粘度懸濁液 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014247793A Pending JP2015083582A (ja) | 2008-11-16 | 2014-12-08 | 高濃度の低粘度懸濁液 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8779094B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2376522A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5711138B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20110103961A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2743789C (cg-RX-API-DMAC7.html) |
| IL (1) | IL212919A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010056657A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5658031B2 (ja) | 2007-06-22 | 2015-01-21 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 薄膜凍結による安定したサブミクロンのペプチド又はタンパク質粒子の形成 |
| CN103096934A (zh) * | 2010-03-09 | 2013-05-08 | 詹森生物科技公司 | 非水性高浓度低粘度混悬剂 |
| US9072668B2 (en) | 2010-03-09 | 2015-07-07 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations of antibodies |
| US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
| US9445990B2 (en) * | 2010-10-06 | 2016-09-20 | Medtronic, Inc. | TNF inhibitor formulation for use in implantable infusion devices |
| AU2012225277A1 (en) * | 2011-03-10 | 2013-09-26 | Board Of Regents, The University Of Texas System | Protein nanoparticle dispersions |
| CN108771655A (zh) * | 2011-10-28 | 2018-11-09 | 诚信生物公司 | 含有氨基酸的蛋白质制剂 |
| EP2776091B1 (en) | 2011-11-07 | 2021-03-03 | Battelle Memorial Institute | Processes for delivery of viscous drug therapies |
| SG10201709555SA (en) * | 2012-05-18 | 2017-12-28 | Genentech Inc | High-concentration monoclonal antibody formulations |
| US20140342006A1 (en) * | 2013-03-15 | 2014-11-20 | Ansun Biopharma, Inc. | Methods for Preparing Injectable Protein Microparticle Suspensions |
| IL312865B2 (en) | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-lowering agents |
| CN103976947B (zh) * | 2014-06-05 | 2016-08-17 | 段明星 | 一种含酶油悬浮剂及其制备方法与应用 |
| KR102497368B1 (ko) * | 2014-10-01 | 2023-02-10 | 이글 바이올로직스 인코포레이티드 | 점도-저하제를 함유하는 폴리삭카라이드 및 핵산 제형 |
| CN107743396B (zh) | 2014-12-12 | 2021-01-15 | Motejo股份有限公司 | 皮下注射用剂 |
| JP5774190B1 (ja) * | 2014-12-12 | 2015-09-09 | ジーンメディカル株式会社 | 皮下注射用剤及び皮下注射用剤を含有する注射器の製造方法 |
| US11459401B2 (en) * | 2016-10-06 | 2022-10-04 | Amgen Inc. | Reduced viscosity protein pharmaceutical formulations |
| EP3544724A4 (en) | 2016-11-22 | 2020-10-14 | Elektrofi, Inc | PARTICLES INCLUDING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND THEIR METHODS OF USE |
| WO2019023392A1 (en) | 2017-07-25 | 2019-01-31 | Elektrofi, Inc. | FORMATION OF PARTICLES COMPRISING AGENTS |
| US12115262B2 (en) | 2018-05-24 | 2024-10-15 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| KR102051808B1 (ko) | 2018-07-23 | 2019-12-04 | 주식회사 종근당 | 테스토스테론 운데카노에이트를 포함하는 안정한 약제학적 조성물 |
| AU2020214626B2 (en) | 2019-01-31 | 2025-10-16 | Elektrofi, Inc. | Particle formation and morphology |
| KR20210125032A (ko) | 2019-02-05 | 2021-10-15 | 린디 바이오사이언시스, 아이엔씨. | 세포 배양 성분 및 액체 세포 배양 배지로부터 이를 단리하는 방법 |
| US20200376128A1 (en) * | 2019-06-01 | 2020-12-03 | Lupin Holdings B.V. | Monodisperse resorbable polyester polymer compositions, systems, and methods |
| AU2020344675A1 (en) * | 2019-09-13 | 2022-03-31 | Elektrofi, Inc. | Compositions and methods for the delivery of therapeutic biologics for treatment of disease |
| JP2023522627A (ja) | 2020-04-17 | 2023-05-31 | エレクトロフィ,インコーポレイテッド | 連続的な液滴形成及び脱水によって粒子を形成する方法 |
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| BE795516A (fr) | 1972-02-17 | 1973-08-16 | Ciba Geigy | Preparations de peptides huileuses et injectables et procede pour leur preparation |
| US4310516A (en) | 1980-02-01 | 1982-01-12 | Block Drug Company Inc. | Cosmetic and pharmaceutical vehicle thickened with solid emulsifier |
| EP0079143A3 (en) | 1981-10-20 | 1984-11-21 | Adnovum Ag | Pseudoplastic gel transfer |
| US4594108A (en) | 1983-09-19 | 1986-06-10 | The Dow Chemical Company | Highly pseudoplastic polymer solutions |
| US5411951A (en) | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
| US5288479A (en) | 1989-01-17 | 1994-02-22 | Sterling Drug, Inc. | Extrudable elastic oral pharmaceutical gel compositions and metered dose dispensers containing them and method of making and method of use thereof |
| SE465950B (sv) | 1989-10-23 | 1991-11-25 | Medinvent Sa | Kombination av ett aggregat partikelformat, kristallint eller frystorkat laekemedel med en pseudoplastisk gel foer beredning av ett injicerbart preparat samt foerfarande foer dess framstaellning |
| US5300302A (en) | 1990-10-04 | 1994-04-05 | Nestec S.A. | Pharmaceutical composition in gel form in a dispensing package |
| YU87892A (sh) | 1991-10-01 | 1995-12-04 | Eli Lilly And Company Lilly Corporate Center | Injektibilne formulacije produženog otpuštanja i postupci za njihovo dobijanje i primenu |
| AU3941493A (en) | 1992-03-30 | 1993-11-08 | Alza Corporation | Viscous suspensions of controlled-release drug particles |
| US5571525A (en) | 1992-03-30 | 1996-11-05 | Alza Corporation | Erosion rate modifier for use in bioerodible drug delivery devices and method of use |
| US5512293A (en) | 1992-07-23 | 1996-04-30 | Alza Corporation | Oral sustained release drug delivery device |
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| DE69431533T2 (de) | 1994-06-13 | 2003-10-02 | Alza Corp., Palo Alto | Dosierungsform zur verabreichung von flüssige arzneimittel formulierung |
| US5904935A (en) | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
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| IN184589B (cg-RX-API-DMAC7.html) | 1996-10-16 | 2000-09-09 | Alza Corp | |
| US7393630B2 (en) | 1997-12-16 | 2008-07-01 | Novartis Vaccines And Diagnostics, Inc. | Use of microparticles combined with submicron oil-in-water emulsions |
| ATE322889T1 (de) | 1999-02-08 | 2006-04-15 | Alza Corp | Stabile nicht wässerige einphasige visköse vehikeln und formulierungen die diese vehikeln verwenden |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| FR2809309B1 (fr) * | 2000-05-23 | 2004-06-11 | Mainelab | Microspheres a liberation prolongee pour administration injectable |
| DE60138641D1 (de) | 2000-10-27 | 2009-06-18 | Baxter Healthcare Sa | Herstellung von mikrokügelchen |
| US20040022861A1 (en) * | 2001-01-30 | 2004-02-05 | Williams Robert O. | Process for production of nanoparticles and microparticles by spray freezing into liquid |
| JP4724354B2 (ja) * | 2001-02-23 | 2011-07-13 | ジェネンテック, インコーポレイテッド | 注射用の崩壊性ポリマー |
| AU2002322295C1 (en) * | 2001-06-21 | 2008-12-18 | Altus Pharmaceuticals Inc. | Spherical protein particles and methods of making and using them |
| EP1578394A4 (en) | 2002-12-31 | 2011-02-23 | Nektar Therapeutics | ANTIBODY PARTICLES AND COMPOSITIONS |
| BRPI0403964B8 (pt) * | 2003-04-04 | 2021-05-25 | Genentech Inc | formulações líquidas estáveis, artigo manufaturado e uso dessas formulações para o tratamento de disfunção mediada por ige |
| CA2540695A1 (en) * | 2003-06-24 | 2004-12-29 | Baxter International Inc. | Specific delivery of drugs to the brain |
| KR101137785B1 (ko) | 2003-07-18 | 2012-04-25 | 백스터 인터내셔널 인코포레이티드 | 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물 |
| FR2862536B1 (fr) * | 2003-11-21 | 2007-11-23 | Flamel Tech Sa | Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques |
| US8728525B2 (en) | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| MXPA06012992A (es) | 2004-05-12 | 2007-02-12 | Baxter Int | Microesferas que comprenden proteina y que muestran inyectabilidad en altas concentraciones de este agente. |
| US20060141040A1 (en) * | 2004-12-23 | 2006-06-29 | Guohua Chen | Injectable non-aqueous suspension |
| WO2006083761A2 (en) * | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US20070015689A1 (en) | 2005-06-23 | 2007-01-18 | Alza Corporation | Complexation of metal ions with polypeptides |
| AU2006330627A1 (en) | 2005-12-16 | 2007-07-05 | University Of Kansas | Nanoclusters for delivery of therapeutics |
| US20090304599A1 (en) | 2005-12-20 | 2009-12-10 | Fujifilm Corporation | Protein Nanoparticles and the Use of the Same |
| US20080102128A1 (en) * | 2006-07-28 | 2008-05-01 | Flamel Technologies, Inc. | Modified-release microparticles based on amphiphilic copolymer and on active principles(s) and pharmaceutical formulations comprising them |
| JP5658031B2 (ja) * | 2007-06-22 | 2015-01-21 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 薄膜凍結による安定したサブミクロンのペプチド又はタンパク質粒子の形成 |
| CN101081882A (zh) * | 2007-07-06 | 2007-12-05 | 天津大学 | 大分子印迹交联聚乙烯基吡咯烷酮微球及低温悬浮聚合制备方法 |
| JP2009173610A (ja) | 2008-01-28 | 2009-08-06 | Fujifilm Corp | タンパク質ナノ粒子 |
| BRPI0909780B1 (pt) | 2008-03-05 | 2022-05-03 | Baxter International Inc | Suspensão contendo uma partícula com superfície modificada, composição farmacêutica compreendendo a referida suspensão, método para aprimorar a absorção celular de um agente ativo, uso de partículas com superfície modificada, e método de preparação de uma partícula com superfície modificada |
| RU2010146684A (ru) | 2008-05-09 | 2012-06-20 | Саут Дакота Стейт Юниверсити (US) | Способ получения неиммуногенных гидрофобных белковых наночастиц и их применения |
| US20100009007A1 (en) | 2008-07-10 | 2010-01-14 | Baxter International Inc. | Non-covalent modification of microparticles and process of preparing same |
| US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| WO2010100200A2 (en) | 2009-03-05 | 2010-09-10 | Novartis Ag | Lyophilised antibody formulation |
-
2009
- 2009-11-10 EP EP09826617.4A patent/EP2376522A4/en not_active Withdrawn
- 2009-11-10 KR KR1020117013867A patent/KR20110103961A/ko not_active Withdrawn
- 2009-11-10 JP JP2011536414A patent/JP5711138B2/ja not_active Expired - Fee Related
- 2009-11-10 US US13/129,283 patent/US8779094B2/en active Active
- 2009-11-10 WO PCT/US2009/063852 patent/WO2010056657A2/en not_active Ceased
- 2009-11-10 CA CA2743789A patent/CA2743789C/en active Active
-
2011
- 2011-05-16 IL IL212919A patent/IL212919A/en active IP Right Grant
-
2014
- 2014-06-05 US US14/297,403 patent/US20140378370A1/en not_active Abandoned
- 2014-12-08 JP JP2014247793A patent/JP2015083582A/ja active Pending
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