JP2012506440A - 環系芳香族のフッ素化 - Google Patents

環系芳香族のフッ素化 Download PDF

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JP2012506440A
JP2012506440A JP2011533270A JP2011533270A JP2012506440A JP 2012506440 A JP2012506440 A JP 2012506440A JP 2011533270 A JP2011533270 A JP 2011533270A JP 2011533270 A JP2011533270 A JP 2011533270A JP 2012506440 A JP2012506440 A JP 2012506440A
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protecting group
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aryl
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JP2012506440A5 (enExample
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ディマグノ，ステファン
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ヌテク ベンチャーズ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
    • C07C271/66—Y being a hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP2011533270A 2008-10-21 2009-10-20 環系芳香族のフッ素化 Withdrawn JP2012506440A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10715608P 2008-10-21 2008-10-21
US61/107,156 2008-10-21
US23603709P 2009-08-21 2009-08-21
US61/236,037 2009-08-21
PCT/US2009/061308 WO2010048170A2 (en) 2008-10-21 2009-10-20 Fluorination of aromatic ring systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015107073A Division JP6049804B2 (ja) 2008-10-21 2015-05-27 環系芳香族のフッ素化

Publications (2)

Publication Number Publication Date
JP2012506440A true JP2012506440A (ja) 2012-03-15
JP2012506440A5 JP2012506440A5 (enExample) 2012-11-29

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JP2011533270A Withdrawn JP2012506440A (ja) 2008-10-21 2009-10-20 環系芳香族のフッ素化
JP2015107073A Active JP6049804B2 (ja) 2008-10-21 2015-05-27 環系芳香族のフッ素化

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Country Status (7)

Country Link
US (1) US8604213B2 (enExample)
EP (3) EP3284736B1 (enExample)
JP (2) JP2012506440A (enExample)
AU (1) AU2009307715B2 (enExample)
CA (1) CA2741967A1 (enExample)
ES (2) ES2627825T3 (enExample)
WO (1) WO2010048170A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016503401A (ja) * 2012-10-27 2016-02-04 グランド・フルーア・ファーマスーティカルズ・インコーポレイテッド ジアリールヨードニウム塩を製造するための方法及び試薬
JP2020180115A (ja) * 2019-04-24 2020-11-05 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法

Families Citing this family (14)

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ES2627825T3 (es) 2008-10-21 2017-07-31 Nutech Ventures Fluoración de sistemas de anillos aromáticos
US9302990B2 (en) * 2008-10-21 2016-04-05 Nutech Ventures Fluorination of aromatic ring systems
US8377704B2 (en) * 2009-10-20 2013-02-19 Nutech Ventures Detection and quantification of anions
US8546578B2 (en) 2010-02-04 2013-10-01 Nutech Ventures Iodonium Cyclophanes for SECURE arene functionalization
US20120309796A1 (en) 2011-06-06 2012-12-06 Fariborz Firooznia Benzocycloheptene acetic acids
CA2875622A1 (en) 2012-06-05 2013-12-12 Nutech Ventures Processes and reagents for making diaryliodonium salts
WO2014022224A1 (en) * 2012-08-02 2014-02-06 The Penn State Research Foundation Polymer conductor for lithium-ion batteries
US9018172B2 (en) 2012-09-26 2015-04-28 Massachusetts Institute Of Technology Modification of peptides via SNAr reactions of thiols with fluorinated aromatics
CA2935856A1 (en) * 2014-01-03 2015-10-01 Nutech Ventures Radioiodinated compounds
WO2015157597A1 (en) * 2014-04-11 2015-10-15 The Regents Of The University Of Michigan Copper catalyzed [18f]fluorination of iodonium salts
US9181297B1 (en) 2014-05-15 2015-11-10 Massachusetts Institute Of Technology Cysteine arylation directed by a genetically encodable π-clamp
US20170001957A1 (en) * 2015-06-12 2017-01-05 Nutech Ventures Radioiodinated bioconjugation reagents
CN109384806B (zh) * 2017-08-03 2021-04-27 王璐 一种[18f]fbpa新型制备方法
CN110862367A (zh) * 2019-11-18 2020-03-06 上海兆维科技发展有限公司 一种香豆素芳基醚类化合物及其制备方法与应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS635039A (ja) * 1986-06-26 1988-01-11 Sagami Chem Res Center 芳香族フツ素化合物の製造方法
JP2007515465A (ja) * 2003-12-23 2007-06-14 ジーイー・ヘルスケア・リミテッド ヨードニウム塩のフッ素化におけるラジカル捕捉剤
JP2007532524A (ja) * 2004-04-08 2007-11-15 ジーイー・ヘルスケア・リミテッド フッ素化方法

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GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
GB0206117D0 (en) 2002-03-15 2002-04-24 Imaging Res Solutions Ltd Use of microfabricated devices
GB0229683D0 (en) 2002-12-20 2003-01-29 Imaging Res Solutions Ltd Preparation of radiopharmaceuticals
GB0320313D0 (en) 2003-08-29 2003-10-01 Ic Innovations Ltd Process
US20060128031A1 (en) 2004-12-15 2006-06-15 Robotti Karla M Addressable recovery of bound analytes from an evanescent wave sensor
JP4931181B2 (ja) * 2006-01-31 2012-05-16 独立行政法人放射線医学総合研究所 １８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法
PT2046396E (pt) 2006-07-18 2013-12-09 Univ Nebraska Agentes de fluoração anidro 18f radioactivamente marcados e métodos para a sua produção e utilização
GB0808986D0 (en) 2008-05-16 2008-06-25 Univ Newcastle Formation of 18F and 19F fluoroarenes bearing reactive functionalities
WO2010008522A2 (en) 2008-07-14 2010-01-21 The Regents Of The University Of California Nucleophilic fluorination of aromatic compounds
GB0814893D0 (en) 2008-08-14 2008-09-17 Ge Healthcare Ltd Improved fluoridation of iodonium salts
ES2627825T3 (es) 2008-10-21 2017-07-31 Nutech Ventures Fluoración de sistemas de anillos aromáticos
US9302990B2 (en) 2008-10-21 2016-04-05 Nutech Ventures Fluorination of aromatic ring systems
US8377704B2 (en) 2009-10-20 2013-02-19 Nutech Ventures Detection and quantification of anions
US8546578B2 (en) 2010-02-04 2013-10-01 Nutech Ventures Iodonium Cyclophanes for SECURE arene functionalization

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS635039A (ja) * 1986-06-26 1988-01-11 Sagami Chem Res Center 芳香族フツ素化合物の製造方法
JP2007515465A (ja) * 2003-12-23 2007-06-14 ジーイー・ヘルスケア・リミテッド ヨードニウム塩のフッ素化におけるラジカル捕捉剤
JP2007532524A (ja) * 2004-04-08 2007-11-15 ジーイー・ヘルスケア・リミテッド フッ素化方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6011011250; Ｊ．ＣＨＥＭ．ＳＯＣ．ＰＥＲＫＩＮ　ＴＲＡＮＳ．　１， Ｖｏｌ．１３，, Ｐ．２０４３-２０４６ *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016503401A (ja) * 2012-10-27 2016-02-04 グランド・フルーア・ファーマスーティカルズ・インコーポレイテッド ジアリールヨードニウム塩を製造するための方法及び試薬
JP2020180115A (ja) * 2019-04-24 2020-11-05 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7545813B2 (ja) 2019-04-24 2024-09-05 住友化学株式会社 レジスト組成物及びレジストパターンの製造方法

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Publication number Publication date
US8604213B2 (en) 2013-12-10
AU2009307715B2 (en) 2015-08-27
EP2537826A1 (en) 2012-12-26
JP2015180668A (ja) 2015-10-15
AU2009307715A1 (en) 2010-04-29
EP2349977A4 (en) 2012-03-28
WO2010048170A3 (en) 2010-07-08
EP2349977A2 (en) 2011-08-03
ES2861578T3 (es) 2021-10-06
JP6049804B2 (ja) 2016-12-21
ES2627825T3 (es) 2017-07-31
US20120004417A1 (en) 2012-01-05
WO2010048170A2 (en) 2010-04-29
EP2537826B1 (en) 2017-03-08
CA2741967A1 (en) 2010-04-29
EP3284736A1 (en) 2018-02-21
EP3284736B1 (en) 2021-03-03

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