JP2012505162A - 黄斑変性症関連障害を処置するためのscyllo−イノシトールの使用 - Google Patents

黄斑変性症関連障害を処置するためのscyllo−イノシトールの使用 Download PDF

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JP2012505162A
JP2012505162A JP2011530339A JP2011530339A JP2012505162A JP 2012505162 A JP2012505162 A JP 2012505162A JP 2011530339 A JP2011530339 A JP 2011530339A JP 2011530339 A JP2011530339 A JP 2011530339A JP 2012505162 A JP2012505162 A JP 2012505162A
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scyllo
macular degeneration
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inositol
therapy
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JP2012505162A5 (enExample
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アントニオ クルツ,
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ワラタ ファーマシューティカルズ, インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011530339A 2008-10-09 2009-10-09 黄斑変性症関連障害を処置するためのscyllo−イノシトールの使用 Pending JP2012505162A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10409408P 2008-10-09 2008-10-09
US61/104,094 2008-10-09
PCT/CA2009/001448 WO2010040232A1 (en) 2008-10-09 2009-10-09 Use of scyllo-inositols for the treatment of macular degeneration-related disorders

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JP2012505162A true JP2012505162A (ja) 2012-03-01
JP2012505162A5 JP2012505162A5 (enExample) 2012-11-22

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JP2011530339A Pending JP2012505162A (ja) 2008-10-09 2009-10-09 黄斑変性症関連障害を処置するためのscyllo−イノシトールの使用

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US (1) US20100093648A1 (enExample)
EP (1) EP2349233A4 (enExample)
JP (1) JP2012505162A (enExample)
AU (1) AU2009301603A1 (enExample)
CA (1) CA2740124A1 (enExample)
WO (1) WO2010040232A1 (enExample)
ZA (1) ZA201102640B (enExample)

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EP2044951A1 (en) 2007-10-02 2009-04-08 Merz Pharma GmbH & Co. KGaA The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases
US20210121430A1 (en) 2011-07-18 2021-04-29 Prn Physician Recommended Nutriceuticals, Llc Omega-3 fatty acid supplementation for use in treating dry eye
US9115078B2 (en) 2011-07-18 2015-08-25 Physicians Recommended Nutriceuticals, Llc Compositions for improving the quality of the meibum composition of inflamed or dysfunctional meibomian glands
US9381183B2 (en) 2012-07-18 2016-07-05 Physicians Recommended Nutriceuticals, Llc Methods for improving the quality of the meibum composition of meibomian glands
US10709680B2 (en) 2011-07-18 2020-07-14 Physicians Recommended Nutriceuticals, Llc Methods for treating dry eye
PT3858405T (pt) 2012-06-01 2023-06-26 Novartis Ag Seringa
TW201412325A (zh) 2012-06-20 2014-04-01 梅茲製藥有限兩合公司 用於治療患有青光眼及其他退化性眼疾之人類視力喪失的間隔醫療
CN103070992B (zh) * 2013-01-11 2014-07-02 管学刚 一种治疗高度近视黄斑出血药物
CA2939121C (en) 2014-01-28 2020-11-24 Mayo Foundation For Medical Education And Research Effective treatment of osteoarthritis, pulmonary disease, ophthalmic disease, and atherosclerosis by removing senescent cells at the site of the disease
WO2015116735A1 (en) 2014-01-28 2015-08-06 Mayo Foundation For Medical Education And Research Methods and combinations for killing senescent cells and for treating senescence-associated diseases and disorders
US10328058B2 (en) 2014-01-28 2019-06-25 Mayo Foundation For Medical Education And Research Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques
US9173915B1 (en) 2014-10-10 2015-11-03 Peter F. Kador Antioxidant eye drops
EP3233174B1 (en) 2014-12-19 2021-03-31 Kemin Industries, Inc. Intraocular delivery of bioactive molecules using iontophoresis
RU2718065C2 (ru) * 2016-02-15 2020-03-30 Кемин Индастриз, Инк. Положительно заряженные липосомы в качестве липофильных молекул-носителей
WO2019213462A1 (en) * 2018-05-03 2019-11-07 Normoxys, Inc. Inositol-based immunotherapies
WO2022155242A1 (en) * 2021-01-12 2022-07-21 The Regents Of The University Of Michigan Treatment and prevention of dry macular degeneration

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JP2006522740A (ja) * 2003-02-27 2006-10-05 ジョアン マクローリン, タンパク質凝集性障害を予防、処置および診断をする方法
JP2007518672A (ja) * 2003-06-23 2007-07-12 ニューロケム (インターナショナル) リミテッド アミロイド阻害化合物の薬学的製剤
JP2008504372A (ja) * 2004-06-18 2008-02-14 ニューロケム (インターナショナル) リミティッド β−アミロイド関連疾患の治療のための治療用製剤
JP2008520589A (ja) * 2004-11-17 2008-06-19 ジョアン マクローリン, シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法
JP2010523602A (ja) * 2007-04-12 2010-07-15 ワラタ ファーマシューティカルズ, インコーポレイテッド 眼疾患の治療におけるシクロヘキサンヘキソール誘導体の使用

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US20050197393A1 (en) * 1999-10-22 2005-09-08 Kim Darrick S.H. Pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease
JP2006522740A (ja) * 2003-02-27 2006-10-05 ジョアン マクローリン, タンパク質凝集性障害を予防、処置および診断をする方法
JP2007518672A (ja) * 2003-06-23 2007-07-12 ニューロケム (インターナショナル) リミテッド アミロイド阻害化合物の薬学的製剤
JP2008504372A (ja) * 2004-06-18 2008-02-14 ニューロケム (インターナショナル) リミティッド β−アミロイド関連疾患の治療のための治療用製剤
JP2008520589A (ja) * 2004-11-17 2008-06-19 ジョアン マクローリン, シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法
JP2010523602A (ja) * 2007-04-12 2010-07-15 ワラタ ファーマシューティカルズ, インコーポレイテッド 眼疾患の治療におけるシクロヘキサンヘキソール誘導体の使用

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WO2010040232A1 (en) 2010-04-15
EP2349233A4 (en) 2012-04-18
US20100093648A1 (en) 2010-04-15
ZA201102640B (en) 2012-09-26
CA2740124A1 (en) 2010-04-15
EP2349233A1 (en) 2011-08-03
AU2009301603A1 (en) 2010-04-15

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