JP2012504955A5 - - Google Patents
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- JP2012504955A5 JP2012504955A5 JP2011530592A JP2011530592A JP2012504955A5 JP 2012504955 A5 JP2012504955 A5 JP 2012504955A5 JP 2011530592 A JP2011530592 A JP 2011530592A JP 2011530592 A JP2011530592 A JP 2011530592A JP 2012504955 A5 JP2012504955 A5 JP 2012504955A5
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- JP
- Japan
- Prior art keywords
- seq
- variable region
- chain variable
- amino acid
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10491108P | 2008-10-13 | 2008-10-13 | |
| US61/104,911 | 2008-10-13 | ||
| PCT/IB2009/007372 WO2010043977A2 (en) | 2008-10-13 | 2009-10-13 | Dengue virus neutralizing antibodies and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015112584A Division JP2016020334A (ja) | 2008-10-13 | 2015-06-02 | デングウイルス中和抗体およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012504955A JP2012504955A (ja) | 2012-03-01 |
| JP2012504955A5 true JP2012504955A5 (cg-RX-API-DMAC7.html) | 2012-11-29 |
| JP5814790B2 JP5814790B2 (ja) | 2015-11-17 |
Family
ID=42102977
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011530592A Expired - Fee Related JP5814790B2 (ja) | 2008-10-13 | 2009-10-13 | デングウイルス中和抗体およびその使用 |
| JP2015112584A Pending JP2016020334A (ja) | 2008-10-13 | 2015-06-02 | デングウイルス中和抗体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015112584A Pending JP2016020334A (ja) | 2008-10-13 | 2015-06-02 | デングウイルス中和抗体およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9073981B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2334700B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5814790B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN108610416B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009305113B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0914012B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2739551C (cg-RX-API-DMAC7.html) |
| MX (1) | MX2011003588A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ592054A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010043977A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009041613A1 (ja) | 2007-09-26 | 2009-04-02 | Chugai Seiyaku Kabushiki Kaisha | 抗体定常領域改変体 |
| ES2644236T3 (es) * | 2010-12-14 | 2017-11-28 | National University Of Singapore | Anticuerpo humano monoclonal con especificidad para el virus Dengue serotipo 1 E proteína y usos de la misma |
| AU2012305807B2 (en) * | 2011-09-09 | 2015-08-20 | Department of Medical Sciences (DMSc) | Dengue-virus serotype neutralizing antibodies |
| WO2013173348A1 (en) * | 2012-05-14 | 2013-11-21 | The Usa, As Represented By The Secretary, Dept. Of Health & Human Services | Cross-reactive antibodies against dengue virus and uses thereof |
| AU2013299986B2 (en) | 2012-08-07 | 2018-05-17 | Massachusetts Institute Of Technology | Anti-dengue virus antibodies and uses thereof |
| KR20230156146A (ko) * | 2012-12-13 | 2023-11-13 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | Ｄｎａ 항체 작제물 및 그 이용 방법 |
| JP7078350B2 (ja) | 2013-10-28 | 2022-05-31 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Ｄｎａ抗体構築物及びその使用方法 |
| WO2015089492A2 (en) * | 2013-12-13 | 2015-06-18 | The Trustees Of The University Of Pennsylvania | Dna antibody constructs and method of using same |
| JP6154126B2 (ja) * | 2012-12-20 | 2017-06-28 | 功 宮崎 | 検査キットおよび検査方法 |
| CA2901358C (en) * | 2013-03-15 | 2022-07-26 | Dana-Farber Cancer Institute, Inc. | Flavivirus neutralizing antibodies and methods of use thereof |
| CN103396481B (zh) * | 2013-07-18 | 2015-06-03 | 华南理工大学 | 一种二型登革热病毒ns1蛋白的重链单域抗体及其制备方法和应用 |
| WO2015095511A2 (en) * | 2013-12-20 | 2015-06-25 | The Scripps Research Institute | Functional antibodies that modulate cell death and related methods |
| KR102356951B1 (ko) | 2014-02-11 | 2022-01-27 | 비스테라, 인크. | 뎅기열 바이러스에 대한 항체 분자 및 그의 용도 |
| US9902764B2 (en) | 2014-02-11 | 2018-02-27 | Massachusetts Institute Of Technology | Full spectrum anti-dengue antibody |
| CN107074968B (zh) * | 2014-09-01 | 2021-03-12 | 国际遗传工程和生物技术中心 | 疫苗 |
| KR20170085131A (ko) | 2014-12-01 | 2017-07-21 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | Dna 항체 작제물 및 그 이용 방법 |
| CN107108729A (zh) | 2015-02-05 | 2017-08-29 | 中外制药株式会社 | 包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il‑8‑结合抗体，及其应用 |
| US10316078B2 (en) | 2015-03-17 | 2019-06-11 | Agency For Science, Technology And Research | Serotype cross-reactive, dengue neutralizing antibody and uses thereof |
| WO2017011495A1 (en) * | 2015-07-14 | 2017-01-19 | Vanderbilt University | Engineered antibodies against dengue virus |
| JP7155009B2 (ja) | 2016-03-25 | 2022-10-18 | ビステラ， インコーポレイテッド | デングウイルスに対する抗体分子の製剤 |
| TWI831965B (zh) | 2016-08-05 | 2024-02-11 | 日商中外製藥股份有限公司 | Il-8相關疾病之治療用或預防用組成物 |
| SG10201607778XA (en) | 2016-09-16 | 2018-04-27 | Chugai Pharmaceutical Co Ltd | Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use |
| TWI769185B (zh) * | 2016-10-27 | 2022-07-01 | 海樂源有限公司 | 登革熱類病毒顆粒、抗登革熱病毒抗體、及含其之組合物 |
| WO2018081755A1 (en) * | 2016-10-29 | 2018-05-03 | University Of Miami | Zika virus antibodies |
| US11249082B2 (en) | 2016-10-29 | 2022-02-15 | University Of Miami | Zika virus assay systems |
| JP7508368B2 (ja) | 2018-03-15 | 2024-07-01 | 中外製薬株式会社 | ジカウイルスに対して交差反応性を有する抗デングウイルス抗体および使用方法 |
| KR102238183B1 (ko) | 2018-05-04 | 2021-04-12 | 가톨릭대학교 산학협력단 | 유전자 합성을 통해 설계된 뎅기열 바이러스의 유전형 복합 ｎｓ１ 재조합 항원 및 대조군 유행성 플라비바이러스 유전형 복합 ns1 재조합 항원 풀 |
| US11830582B2 (en) | 2018-06-14 | 2023-11-28 | University Of Miami | Methods of designing novel antibody mimetics for use in detecting antigens and as therapeutic agents |
| WO2020078568A1 (en) | 2018-10-19 | 2020-04-23 | Humabs Biomed Sa | Antibodies and methods for treatment of lyssavirus infection |
| CN111320688B (zh) * | 2018-12-17 | 2021-08-24 | 中国科学院天津工业生物技术研究所 | 一种黄病毒中和抗体、其制备方法及应用 |
| KR102048812B1 (ko) * | 2018-12-19 | 2019-11-26 | 주식회사 엠디헬스케어 | 뎅기 바이러스 ediii에 특이적으로 결합하는 dna 압타머 및 이의 용도 |
| JP2023526469A (ja) * | 2020-05-20 | 2023-06-21 | ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | ＳＡＲＳ－ＣｏＶ－２に対する強力な中和抗体、その生成および使用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB819376A (en) | 1956-10-20 | 1959-09-02 | Colne Switchgear K & W Ltd | Improvements in electro-magnetic overload units for electrical apparatus |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS5896026A (ja) | 1981-10-30 | 1983-06-07 | Nippon Chemiphar Co Ltd | 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤 |
| DE3380726D1 (en) | 1982-06-24 | 1989-11-23 | Japan Chem Res | Long-acting composition |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US4766106A (en) | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US4831175A (en) | 1986-09-05 | 1989-05-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| US5595721A (en) | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| CU22683A1 (es) * | 1997-01-15 | 2001-07-20 | Inst De Medicina Tropical Pedro Kouri | Epítopes de la proteína pre-m/m del virus del dengue, péptidos sintéticos, proteínas quiméricas y sus usos |
| AU8063798A (en) | 1997-06-19 | 1999-01-04 | Regents Of The University Of California, The | Secretory immunoglobulin produced by single cells and methods for making and using same |
| EP1034298B1 (en) | 1997-12-05 | 2011-11-02 | The Scripps Research Institute | Humanization of murine antibody |
| US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
| MY133346A (en) | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
| DK1517921T3 (da) | 2002-06-28 | 2006-10-09 | Domantis Ltd | Immunglobulin-enkeltvariable antigen-bindende domæner og dobbeltspecifikke konstruktioner deraf |
| US7473424B2 (en) * | 2003-01-31 | 2009-01-06 | The Scripps Research Institute | Anti-dengue virus antibodies and compositions |
| WO2004076677A2 (en) | 2003-02-26 | 2004-09-10 | Institute For Research In Biomedicine | Monoclonal antibody production by ebv transformation of b cells |
| CA2548808C (en) * | 2003-12-08 | 2015-07-07 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Monoclonal antibodies that bind or neutralize dengue virus |
| EP2990053A1 (en) | 2004-01-20 | 2016-03-02 | KaloBios Pharmaceuticals, Inc. | Antibody specificity transfer using minimal essential binding determinants |
| CU23586A1 (es) * | 2005-11-22 | 2010-10-30 | Ct Ingenieria Genetica Biotech | Métodos y proteínas para el tratamiento profiláctico y/o terapéutico de los cuatro serotipos del virus de dengue y otros flavivirus |
| EP2144931A2 (en) * | 2007-04-04 | 2010-01-20 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Monoclonal antibodies against dengue and other viruses with deletion in fc region |
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2009
- 2009-10-13 CN CN201810446003.6A patent/CN108610416B/zh not_active Expired - Fee Related
- 2009-10-13 JP JP2011530592A patent/JP5814790B2/ja not_active Expired - Fee Related
- 2009-10-13 CN CN200980140759.7A patent/CN102272155B/zh not_active Expired - Fee Related
- 2009-10-13 MX MX2011003588A patent/MX2011003588A/es active IP Right Grant
- 2009-10-13 AU AU2009305113A patent/AU2009305113B2/en not_active Ceased
- 2009-10-13 EP EP09799385.1A patent/EP2334700B1/en active Active
- 2009-10-13 WO PCT/IB2009/007372 patent/WO2010043977A2/en not_active Ceased
- 2009-10-13 BR BRPI0914012-3A patent/BRPI0914012B1/pt active IP Right Grant
- 2009-10-13 CA CA2739551A patent/CA2739551C/en active Active
- 2009-10-13 NZ NZ592054A patent/NZ592054A/xx not_active IP Right Cessation
- 2009-10-13 US US13/124,076 patent/US9073981B2/en active Active
-
2015
- 2015-06-02 JP JP2015112584A patent/JP2016020334A/ja active Pending