JP2012501181A5 - - Google Patents
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- JP2012501181A5 JP2012501181A5 JP2011525187A JP2011525187A JP2012501181A5 JP 2012501181 A5 JP2012501181 A5 JP 2012501181A5 JP 2011525187 A JP2011525187 A JP 2011525187A JP 2011525187 A JP2011525187 A JP 2011525187A JP 2012501181 A5 JP2012501181 A5 JP 2012501181A5
- Authority
- JP
- Japan
- Prior art keywords
- biomarkers
- features
- affective disorder
- disorder
- biomarker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 31
- 239000000090 biomarker Substances 0.000 claims 26
- 208000019022 Mood disease Diseases 0.000 claims 12
- 208000017194 Affective disease Diseases 0.000 claims 11
- 239000012472 biological sample Substances 0.000 claims 5
- 238000004458 analytical method Methods 0.000 claims 4
- 208000024891 symptom Diseases 0.000 claims 4
- 102000007378 beta-Arrestin 1 Human genes 0.000 claims 3
- 108010032969 beta-Arrestin 1 Proteins 0.000 claims 3
- 208000020925 Bipolar disease Diseases 0.000 claims 2
- 101100457345 Danio rerio mapk14a gene Proteins 0.000 claims 2
- 101100457347 Danio rerio mapk14b gene Proteins 0.000 claims 2
- 102000019149 MAP kinase activity proteins Human genes 0.000 claims 2
- 108040008097 MAP kinase activity proteins Proteins 0.000 claims 2
- 108700012928 MAPK14 Proteins 0.000 claims 2
- 101150003941 Mapk14 gene Proteins 0.000 claims 2
- 102000054819 Mitogen-activated protein kinase 14 Human genes 0.000 claims 2
- 238000007405 data analysis Methods 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 208000020401 Depressive disease Diseases 0.000 claims 1
- 101000585693 Homo sapiens Mitochondrial 2-oxodicarboxylate carrier Proteins 0.000 claims 1
- 101001041245 Homo sapiens Ornithine decarboxylase Proteins 0.000 claims 1
- 102100021079 Ornithine decarboxylase Human genes 0.000 claims 1
- 102100037602 P2X purinoceptor 7 Human genes 0.000 claims 1
- 101710189965 P2X purinoceptor 7 Proteins 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 238000013528 artificial neural network Methods 0.000 claims 1
- 208000025748 atypical depressive disease Diseases 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 208000030963 borderline personality disease Diseases 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 238000003066 decision tree Methods 0.000 claims 1
- 208000024732 dysthymic disease Diseases 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 208000024714 major depressive disease Diseases 0.000 claims 1
- 201000003995 melancholia Diseases 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 238000000513 principal component analysis Methods 0.000 claims 1
- 238000012706 support-vector machine Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9227008P | 2008-08-27 | 2008-08-27 | |
| US61/092,270 | 2008-08-27 | ||
| PCT/US2009/055144 WO2010025216A1 (en) | 2008-08-27 | 2009-08-27 | System and methods for measuring biomarker profiles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012501181A JP2012501181A (ja) | 2012-01-19 |
| JP2012501181A5 true JP2012501181A5 (enExample) | 2012-11-08 |
Family
ID=41721907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011525187A Pending JP2012501181A (ja) | 2008-08-27 | 2009-08-27 | バイオマーカー・プロファイルを測定するためのシステムおよび方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110172501A1 (enExample) |
| EP (1) | EP2318551A4 (enExample) |
| JP (1) | JP2012501181A (enExample) |
| KR (1) | KR20110057188A (enExample) |
| CN (1) | CN102224256A (enExample) |
| AU (1) | AU2009285766A1 (enExample) |
| BR (1) | BRPI0914859A2 (enExample) |
| CA (1) | CA2728171A1 (enExample) |
| EA (1) | EA201071324A1 (enExample) |
| WO (1) | WO2010025216A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8655807B2 (en) * | 2010-04-05 | 2014-02-18 | Applied Research Associates, Inc. | Methods for forming recognition algorithms for laser-induced breakdown spectroscopy |
| US8676739B2 (en) | 2010-11-11 | 2014-03-18 | International Business Machines Corporation | Determining a preferred node in a classification and regression tree for use in a predictive analysis |
| US9336302B1 (en) | 2012-07-20 | 2016-05-10 | Zuci Realty Llc | Insight and algorithmic clustering for automated synthesis |
| KR101483284B1 (ko) * | 2013-01-31 | 2015-01-15 | 한국과학기술원 | 질병 관련 단일염기다형성 조합 추출 방법, 질병 발생 위험도 예측 방법, 그리고 이를 이용한 질병 발생 위험도 예측 장치 |
| US20160209428A1 (en) * | 2013-08-21 | 2016-07-21 | The Regents Of The University Of California | Diagnostic and predictive metabolite patterns for disorders affecting the brain and nervous system |
| US11885816B2 (en) | 2013-11-26 | 2024-01-30 | University Of North Texas Health Science Center At Forth Worth | Personalized medicine approach for treating cognitive loss |
| WO2022187670A1 (en) * | 2021-03-05 | 2022-09-09 | University Of North Texas Health Science Center At Fort Worth | Personalized medicine approach for treating cognitive loss |
| US9545227B2 (en) | 2013-12-13 | 2017-01-17 | Vital Connect, Inc. | Sleep apnea syndrome (SAS) screening using wearable devices |
| EP3677914A1 (en) * | 2015-11-12 | 2020-07-08 | Kyushu University National University Corporation | Biomarker for diagnosing depression and use of biomarker |
| US11205103B2 (en) | 2016-12-09 | 2021-12-21 | The Research Foundation for the State University | Semisupervised autoencoder for sentiment analysis |
| JP7097370B2 (ja) * | 2017-01-08 | 2022-07-07 | ザ ヘンリー エム.ジャクソン ファンデーション フォー ザ アドバンスメント オブ ミリタリー メディシン,インコーポレーテッド | 対象特有の菌血症転記を予測するための教師付き学習を使用するためのシステムおよび方法 |
| WO2018160841A1 (en) | 2017-03-01 | 2018-09-07 | Genentech, Inc. | Diagnostic and therapeutic methods for cancer |
| TWI640018B (zh) * | 2017-03-15 | 2018-11-01 | 長庚醫療財團法人林口長庚紀念醫院 | Data integration method |
| CN110537094B (zh) * | 2017-07-07 | 2022-03-08 | 松下知识产权经营株式会社 | 信息提供方法、信息处理系统、信息终端及信息处理方法 |
| US11069431B2 (en) * | 2017-11-13 | 2021-07-20 | The Multiple Myeloma Research Foundation, Inc. | Integrated, molecular, omics, immunotherapy, metabolic, epigenetic, and clinical database |
| CA3019970A1 (en) * | 2018-10-05 | 2020-04-05 | Fang Liu | Methods for diagnosing or treating post-traumatic stress disorder, and compositions therefor |
| US11537888B2 (en) * | 2019-05-15 | 2022-12-27 | The Florida International University Board Of Trustees | Systems and methods for predicting pain level |
| CN113210264B (zh) * | 2021-05-19 | 2023-09-05 | 江苏鑫源烟草薄片有限公司 | 烟草杂物剔除方法及装置 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6190857B1 (en) * | 1997-03-24 | 2001-02-20 | Urocor, Inc. | Diagnosis of disease state using MRNA profiles in peripheral leukocytes |
| US5958688A (en) * | 1997-04-28 | 1999-09-28 | The Trustees Of The University Of Pennsylvania | Characterization of mRNA patterns in neurites and single cells for medical diagnosis and therapeutics |
| NO972006D0 (no) * | 1997-04-30 | 1997-04-30 | Forskningsparken I Aas As | Ny metode for diagnose av sykdommer |
| US20070178475A1 (en) * | 1998-09-17 | 2007-08-02 | Nehls Michael C | Novel human polynucleotides and polypeptides encoded thereby |
| WO2000040749A2 (en) * | 1999-01-06 | 2000-07-13 | Genenews Inc. | Method for the detection of gene transcripts in blood and uses thereof |
| DE10019058A1 (de) * | 2000-04-06 | 2001-12-20 | Epigenomics Ag | Detektion von Variationen des DNA-Methylierungsprofils |
| US7329489B2 (en) * | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| DE08002964T1 (de) * | 2001-02-27 | 2009-09-03 | Blanchette Rockefeller Neurosciences Institute | Alzheimer-Diagnose auf Basis von mitogenaktivierter Proteinkinasephosphorylierung |
| JP3771502B2 (ja) * | 2002-02-14 | 2006-04-26 | 国立大学法人 新潟大学 | 精神分裂病により発現量が変化する遺伝子を規定する核酸を解析する方法 |
| WO2004007762A2 (en) * | 2002-07-11 | 2004-01-22 | Novartis Ag | Genes associated with schizophrenia, adhd and bipolar disorders |
| JP2004135667A (ja) * | 2002-09-27 | 2004-05-13 | Japan Science & Technology Agency | 血液を用いた統合失調症の診断方法 |
| JP2004208547A (ja) * | 2002-12-27 | 2004-07-29 | Hitachi Ltd | うつ病の評価方法 |
| WO2004085614A2 (en) * | 2003-03-21 | 2004-10-07 | The Mclean Hospital Corporation | Nucleic acid molecules that are differentially regulated in a bipolar disorder and uses thereof |
| US20070105105A1 (en) * | 2003-05-23 | 2007-05-10 | Mount Sinai School Of Medicine Of New York University | Surrogate cell gene expression signatures for evaluating the physical state of a subject |
| EP1636376A2 (en) * | 2003-06-13 | 2006-03-22 | The Babraham Institute | Differential gene expression in schizophrenia |
| US20050069936A1 (en) * | 2003-09-26 | 2005-03-31 | Cornelius Diamond | Diagnostic markers of depression treatment and methods of use thereof |
| US20050209181A1 (en) * | 2003-11-05 | 2005-09-22 | Huda Akil | Compositions and methods for diagnosing and treating mental disorders |
| US20050208519A1 (en) * | 2004-03-12 | 2005-09-22 | Genenews Inc. | Biomarkers for diagnosing schizophrenia and bipolar disorder |
| JP2005312435A (ja) * | 2004-03-29 | 2005-11-10 | Kazuhito Rokutan | うつ病の評価方法 |
| CA2568967A1 (en) * | 2004-06-03 | 2005-12-15 | Athlomics Pty Ltd | Agents and methods for diagnosing stress |
| WO2006002262A2 (en) * | 2004-06-21 | 2006-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
| US7736621B2 (en) * | 2004-08-03 | 2010-06-15 | Hypatia Ltd. | Methods for gauging the effect of a depression treatment by determining the levels of beta-arrestin 1 and G-protein coupled receptor kinase 2 |
| WO2006097244A2 (en) * | 2005-03-17 | 2006-09-21 | F. Hoffman-La Roche Ag | Methods for assessing emphysema |
| US20070122395A1 (en) * | 2005-10-06 | 2007-05-31 | Vanderbilt University | Genetic and pharmacological regulation of antidepressant-sensitive biogenic amine transporters through PKG/p38 map kinase |
| US7906281B2 (en) * | 2005-10-07 | 2011-03-15 | The Regents Of The University Of California | Method to predict the response to lithium treatment |
| WO2007044094A1 (en) * | 2005-10-11 | 2007-04-19 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's disease-specific alterations of the erk1/erk2 phosphorylation ratio as alzheimer's disease-specific molecular biomarkers (adsmb) |
| US20080033598A1 (en) * | 2006-03-23 | 2008-02-07 | Hollingsworth Stephen A | Materials management system and method |
| US20070292880A1 (en) * | 2006-05-05 | 2007-12-20 | Robert Philibert | Compositions and methods for detecting predisposition to a substance use disorder or to a mental illness or syndrome |
| US8163475B2 (en) * | 2006-05-18 | 2012-04-24 | The Mclean Hospital Corporation | Methods for diagnosis and prognosis of psychotic disorders |
| EP2044431B1 (en) * | 2006-07-17 | 2019-04-24 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | Computer systems and methods for selecting subjects for clinical trials |
| US9353415B2 (en) * | 2006-12-19 | 2016-05-31 | Thomson Reuters (Scientific) Llc | Methods for functional analysis of high-throughput experimental data and gene groups identified therefrom |
| WO2008124428A1 (en) * | 2007-04-03 | 2008-10-16 | Indiana University Research And Technology Corporation | Blood biomarkers for mood disorders |
| WO2008144371A1 (en) * | 2007-05-16 | 2008-11-27 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for diagnosing suicidal tendencies |
-
2009
- 2009-08-27 EP EP09810557A patent/EP2318551A4/en not_active Withdrawn
- 2009-08-27 CA CA2728171A patent/CA2728171A1/en not_active Abandoned
- 2009-08-27 CN CN2009801428894A patent/CN102224256A/zh active Pending
- 2009-08-27 EA EA201071324A patent/EA201071324A1/ru unknown
- 2009-08-27 BR BRPI0914859A patent/BRPI0914859A2/pt not_active IP Right Cessation
- 2009-08-27 WO PCT/US2009/055144 patent/WO2010025216A1/en not_active Ceased
- 2009-08-27 JP JP2011525187A patent/JP2012501181A/ja active Pending
- 2009-08-27 US US13/000,405 patent/US20110172501A1/en not_active Abandoned
- 2009-08-27 AU AU2009285766A patent/AU2009285766A1/en not_active Abandoned
- 2009-08-27 KR KR1020117007024A patent/KR20110057188A/ko not_active Withdrawn
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