CA2728171A1 - System and methods for measuring biomarker profiles - Google Patents

System and methods for measuring biomarker profiles Download PDF

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Publication number
CA2728171A1
CA2728171A1 CA2728171A CA2728171A CA2728171A1 CA 2728171 A1 CA2728171 A1 CA 2728171A1 CA 2728171 A CA2728171 A CA 2728171A CA 2728171 A CA2728171 A CA 2728171A CA 2728171 A1 CA2728171 A1 CA 2728171A1
Authority
CA
Canada
Prior art keywords
biomarkers
subjects
biomarker
affective disorder
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2728171A
Other languages
English (en)
French (fr)
Inventor
Irina Antonijevic
Joseph Tamm
Roman Artymyshyn
Christophe P. G. Gerald
Jan Bastholm Vistisen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of CA2728171A1 publication Critical patent/CA2728171A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Data Mining & Analysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Artificial Intelligence (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Databases & Information Systems (AREA)
  • Biochemistry (AREA)
  • Evolutionary Computation (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2728171A 2008-08-27 2009-08-27 System and methods for measuring biomarker profiles Abandoned CA2728171A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9227008P 2008-08-27 2008-08-27
US61/092,270 2008-08-27
PCT/US2009/055144 WO2010025216A1 (en) 2008-08-27 2009-08-27 System and methods for measuring biomarker profiles

Publications (1)

Publication Number Publication Date
CA2728171A1 true CA2728171A1 (en) 2010-03-04

Family

ID=41721907

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2728171A Abandoned CA2728171A1 (en) 2008-08-27 2009-08-27 System and methods for measuring biomarker profiles

Country Status (10)

Country Link
US (1) US20110172501A1 (enExample)
EP (1) EP2318551A4 (enExample)
JP (1) JP2012501181A (enExample)
KR (1) KR20110057188A (enExample)
CN (1) CN102224256A (enExample)
AU (1) AU2009285766A1 (enExample)
BR (1) BRPI0914859A2 (enExample)
CA (1) CA2728171A1 (enExample)
EA (1) EA201071324A1 (enExample)
WO (1) WO2010025216A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8655807B2 (en) * 2010-04-05 2014-02-18 Applied Research Associates, Inc. Methods for forming recognition algorithms for laser-induced breakdown spectroscopy
US8676739B2 (en) 2010-11-11 2014-03-18 International Business Machines Corporation Determining a preferred node in a classification and regression tree for use in a predictive analysis
US9336302B1 (en) 2012-07-20 2016-05-10 Zuci Realty Llc Insight and algorithmic clustering for automated synthesis
KR101483284B1 (ko) * 2013-01-31 2015-01-15 한국과학기술원 질병 관련 단일염기다형성 조합 추출 방법, 질병 발생 위험도 예측 방법, 그리고 이를 이용한 질병 발생 위험도 예측 장치
WO2015027116A1 (en) * 2013-08-21 2015-02-26 The Regents Of The University Of California Diagnostic and predictive metabolite patterns for disorders affecting the brain and nervous system
EP3074525B1 (en) 2013-11-26 2024-06-26 University of North Texas Health Science Center at Fort Worth Personalized medicine approach for treating cognitive loss
WO2022187670A1 (en) * 2021-03-05 2022-09-09 University Of North Texas Health Science Center At Fort Worth Personalized medicine approach for treating cognitive loss
US9545227B2 (en) * 2013-12-13 2017-01-17 Vital Connect, Inc. Sleep apnea syndrome (SAS) screening using wearable devices
JP6882776B2 (ja) * 2015-11-12 2021-06-02 国立大学法人九州大学 うつ病診断用バイオマーカー及びその使用
US11205103B2 (en) 2016-12-09 2021-12-21 The Research Foundation for the State University Semisupervised autoencoder for sentiment analysis
US20190354814A1 (en) * 2017-01-08 2019-11-21 Henry M. Jackson Foundation For The Advancement Of Military Medicine Systems and methods for using supervised learning to predict subject-specific bacteremia outcomes
MX2019010295A (es) 2017-03-01 2019-11-21 Genentech Inc Métodos de diagnóstico y terapéuticos para el cáncer.
TWI640018B (zh) * 2017-03-15 2018-11-01 長庚醫療財團法人林口長庚紀念醫院 Data integration method
JP7170250B2 (ja) * 2017-07-07 2022-11-14 パナソニックIpマネジメント株式会社 情報提供方法、情報処理システム、及び情報処理方法
KR102424222B1 (ko) * 2017-11-13 2022-07-21 더 멀티플 마이얼로머 리서치 파운데이션, 인크. 통합된, 분자, 체학, 면역요법, 대사, 후성적, 및 임상 데이터베이스
CA3019970A1 (en) * 2018-10-05 2020-04-05 Fang Liu Methods for diagnosing or treating post-traumatic stress disorder, and compositions therefor
US11537888B2 (en) * 2019-05-15 2022-12-27 The Florida International University Board Of Trustees Systems and methods for predicting pain level
CN113210264B (zh) * 2021-05-19 2023-09-05 江苏鑫源烟草薄片有限公司 烟草杂物剔除方法及装置

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6190857B1 (en) * 1997-03-24 2001-02-20 Urocor, Inc. Diagnosis of disease state using MRNA profiles in peripheral leukocytes
US5958688A (en) * 1997-04-28 1999-09-28 The Trustees Of The University Of Pennsylvania Characterization of mRNA patterns in neurites and single cells for medical diagnosis and therapeutics
NO972006D0 (no) * 1997-04-30 1997-04-30 Forskningsparken I Aas As Ny metode for diagnose av sykdommer
US20070178475A1 (en) * 1998-09-17 2007-08-02 Nehls Michael C Novel human polynucleotides and polypeptides encoded thereby
WO2000040749A2 (en) * 1999-01-06 2000-07-13 Genenews Inc. Method for the detection of gene transcripts in blood and uses thereof
DE10019058A1 (de) * 2000-04-06 2001-12-20 Epigenomics Ag Detektion von Variationen des DNA-Methylierungsprofils
US7329489B2 (en) * 2000-04-14 2008-02-12 Matabolon, Inc. Methods for drug discovery, disease treatment, and diagnosis using metabolomics
ES2305234T3 (es) * 2001-02-27 2008-11-01 Blanchette Rockefeller Neurosciences Institute Diagnostico de la enfermedad de alzheimer basado en la fosforilacion de una proteina quinosa activada por mitogeno.
JP3771502B2 (ja) * 2002-02-14 2006-04-26 国立大学法人 新潟大学 精神分裂病により発現量が変化する遺伝子を規定する核酸を解析する方法
AU2003250033A1 (en) * 2002-07-11 2004-02-02 Novartis Ag Genes associated with schizophrenia, adhd and bipolar disorders
JP2004135667A (ja) * 2002-09-27 2004-05-13 Japan Science & Technology Agency 血液を用いた統合失調症の診断方法
JP2004208547A (ja) * 2002-12-27 2004-07-29 Hitachi Ltd うつ病の評価方法
US20040248286A1 (en) * 2003-03-21 2004-12-09 Christine Konradi Nucleic acid molecules that are differentially regulated in a bipolar disorder and uses thereof
US20070105105A1 (en) * 2003-05-23 2007-05-10 Mount Sinai School Of Medicine Of New York University Surrogate cell gene expression signatures for evaluating the physical state of a subject
US20060150264A1 (en) * 2003-06-13 2006-07-06 Sabine Bahn Differential gene expression in schizophrenia
US20050069936A1 (en) * 2003-09-26 2005-03-31 Cornelius Diamond Diagnostic markers of depression treatment and methods of use thereof
US20050209181A1 (en) * 2003-11-05 2005-09-22 Huda Akil Compositions and methods for diagnosing and treating mental disorders
US20050208519A1 (en) * 2004-03-12 2005-09-22 Genenews Inc. Biomarkers for diagnosing schizophrenia and bipolar disorder
JP2005312435A (ja) * 2004-03-29 2005-11-10 Kazuhito Rokutan うつ病の評価方法
EP1766014A4 (en) * 2004-06-03 2008-12-10 Athlomics Pty Ltd AGENTS AND METHODS FOR THE DIAGNOSIS OF STRESS
ES2660765T3 (es) * 2004-06-21 2018-03-26 The Board Of Trustees Of The Leland Stanford Junior University Genes y rutas expresadas de forma diferencial en trastorno bipolar y/o trastorno depresivo mayor
US7736621B2 (en) * 2004-08-03 2010-06-15 Hypatia Ltd. Methods for gauging the effect of a depression treatment by determining the levels of beta-arrestin 1 and G-protein coupled receptor kinase 2
WO2006097244A2 (en) * 2005-03-17 2006-09-21 F. Hoffman-La Roche Ag Methods for assessing emphysema
US20070122395A1 (en) * 2005-10-06 2007-05-31 Vanderbilt University Genetic and pharmacological regulation of antidepressant-sensitive biogenic amine transporters through PKG/p38 map kinase
US7906281B2 (en) * 2005-10-07 2011-03-15 The Regents Of The University Of California Method to predict the response to lithium treatment
WO2007044094A1 (en) * 2005-10-11 2007-04-19 Blanchette Rockefeller Neurosciences Institute Alzheimer's disease-specific alterations of the erk1/erk2 phosphorylation ratio as alzheimer's disease-specific molecular biomarkers (adsmb)
US20080033598A1 (en) * 2006-03-23 2008-02-07 Hollingsworth Stephen A Materials management system and method
US20070292880A1 (en) * 2006-05-05 2007-12-20 Robert Philibert Compositions and methods for detecting predisposition to a substance use disorder or to a mental illness or syndrome
US8163475B2 (en) * 2006-05-18 2012-04-24 The Mclean Hospital Corporation Methods for diagnosis and prognosis of psychotic disorders
WO2008011046A2 (en) * 2006-07-17 2008-01-24 The H.Lee Moffitt Cancer And Research Institute, Inc. Computer systems and methods for selecting subjects for clinical trials
WO2008079269A2 (en) * 2006-12-19 2008-07-03 Genego, Inc. Novel methods for functional analysis of high-throughput experimental data and gene groups identified therfrom
WO2008124428A1 (en) * 2007-04-03 2008-10-16 Indiana University Research And Technology Corporation Blood biomarkers for mood disorders
WO2008144371A1 (en) * 2007-05-16 2008-11-27 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for diagnosing suicidal tendencies

Also Published As

Publication number Publication date
EA201071324A1 (ru) 2011-12-30
WO2010025216A1 (en) 2010-03-04
JP2012501181A (ja) 2012-01-19
KR20110057188A (ko) 2011-05-31
BRPI0914859A2 (pt) 2015-11-03
WO2010025216A9 (en) 2010-11-18
CN102224256A (zh) 2011-10-19
EP2318551A1 (en) 2011-05-11
AU2009285766A1 (en) 2010-03-04
EP2318551A4 (en) 2012-10-24
US20110172501A1 (en) 2011-07-14

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20150827