JP2012500197A - Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤 - Google Patents

Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤 Download PDF

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Publication number
JP2012500197A
JP2012500197A JP2011523005A JP2011523005A JP2012500197A JP 2012500197 A JP2012500197 A JP 2012500197A JP 2011523005 A JP2011523005 A JP 2011523005A JP 2011523005 A JP2011523005 A JP 2011523005A JP 2012500197 A JP2012500197 A JP 2012500197A
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cell
compound
cancer
rassf1a
cells
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JP2011523005A
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Japanese (ja)
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JP2012500197A5 (cg-RX-API-DMAC7.html
Inventor
ミルトン エル． ブラウン，
キャサリン ディー． シーク，
ミケル ペイジ，
パルサ バネルジー，
シャンカー ジャガディーシュ，
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Georgetown University
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Georgetown University
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Publication of JP2012500197A5 publication Critical patent/JP2012500197A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electroluminescent Light Sources (AREA)
JP2011523005A 2008-08-15 2009-08-14 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤 Pending JP2012500197A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18905908P 2008-08-15 2008-08-15
US61/189,059 2008-08-15
PCT/US2009/004681 WO2010019271A1 (en) 2008-08-15 2009-08-14 Fluorescent regulators of rassf1a expression and human cancer cell proliferation

Related Child Applications (1)

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JP2014105150A Division JP2014148545A (ja) 2008-08-15 2014-05-21 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤

Publications (2)

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JP2012500197A true JP2012500197A (ja) 2012-01-05
JP2012500197A5 JP2012500197A5 (cg-RX-API-DMAC7.html) 2013-05-09

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JP2011523005A Pending JP2012500197A (ja) 2008-08-15 2009-08-14 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤
JP2014105150A Pending JP2014148545A (ja) 2008-08-15 2014-05-21 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤

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Country Status (9)

Country Link
US (1) US10457639B2 (cg-RX-API-DMAC7.html)
EP (2) EP2323982B1 (cg-RX-API-DMAC7.html)
JP (2) JP2012500197A (cg-RX-API-DMAC7.html)
CN (1) CN102186820B (cg-RX-API-DMAC7.html)
AT (1) ATE547403T1 (cg-RX-API-DMAC7.html)
AU (1) AU2009282451B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0917411A2 (cg-RX-API-DMAC7.html)
CA (1) CA2734225A1 (cg-RX-API-DMAC7.html)
WO (1) WO2010019271A1 (cg-RX-API-DMAC7.html)

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WO2018230556A1 (ja) * 2017-06-12 2018-12-20 昇平 宮田 抗癌剤及びその使用

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WO2013040057A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
AU2012308686B2 (en) 2011-09-13 2018-05-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
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AU2013371825B2 (en) 2013-01-01 2019-10-24 A.B. Seeds Ltd. Methods of introducing dsRNA to plant seeds for modulating gene expression
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
BR112015022797A2 (pt) 2013-03-13 2017-11-07 Monsanto Technology Llc método para controle de ervas daninhas, composição herbicida, cassete de expressão microbiano e método de produção de polinucleotídeo
EP2971185A4 (en) 2013-03-13 2017-03-08 Monsanto Technology LLC Methods and compositions for weed control
WO2014151317A1 (en) * 2013-03-15 2014-09-25 Rush University Medical Center Methods for treating cancer
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
MX359191B (es) 2013-07-19 2018-09-18 Monsanto Technology Llc Composiciones y métodos para controlar leptinotarsa.
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
UA120426C2 (uk) 2013-11-04 2019-12-10 Монсанто Текнолоджі Елелсі Композиція та спосіб для боротьби з членистоногими паразитами та зараженням шкідниками
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
BR112016016337A2 (pt) 2014-01-15 2017-10-03 Monsanto Technology Llc Composição e métodos para controlar crescimento, desenvolvimento ou a capacidade de reprodução de uma planta, e para sensibilizar uma planta para um herbicida inibidor de epsps
CN110506752B (zh) 2014-04-01 2022-02-18 孟山都技术公司 用于控制虫害的组合物和方法
EP3158067B1 (en) 2014-06-23 2020-08-12 Monsanto Technology LLC Compositions and methods for regulating gene expression via rna interference
WO2015200539A1 (en) 2014-06-25 2015-12-30 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
US10378012B2 (en) 2014-07-29 2019-08-13 Monsanto Technology Llc Compositions and methods for controlling insect pests
UA124255C2 (uk) 2015-01-22 2021-08-18 Монсанто Текнолоджі Елелсі Інсектицидна композиція та спосіб боротьби з leptinotarsa
UY36703A (es) 2015-06-02 2016-12-30 Monsanto Technology Llc Composiciones y métodos para la administración de un polinucleótido en una planta
AU2016270913A1 (en) 2015-06-03 2018-01-04 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
US10173978B2 (en) 2015-08-05 2019-01-08 Georgetown University Small molecule androgen receptor inhibitors and methods of use thereof
CN107266356B (zh) * 2017-07-25 2020-06-26 山西省生物研究院有限公司 一种作为自分泌运动因子抑制剂的咔唑类化合物及其制备方法和应用

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018230556A1 (ja) * 2017-06-12 2018-12-20 昇平 宮田 抗癌剤及びその使用
CN110785166A (zh) * 2017-06-12 2020-02-11 宫田升平 抗癌药及其用途
JPWO2018230556A1 (ja) * 2017-06-12 2020-06-18 昇平 宮田 抗癌剤及びその使用
US11464750B2 (en) 2017-06-12 2022-10-11 Shohei Miyata Anticancer agent and use thereof
JP7236382B2 (ja) 2017-06-12 2023-03-09 昇平 宮田 抗癌剤及びその使用

Also Published As

Publication number Publication date
CN102186820A (zh) 2011-09-14
HK1158206A1 (en) 2012-07-13
CA2734225A1 (en) 2010-02-18
US10457639B2 (en) 2019-10-29
WO2010019271A8 (en) 2011-03-31
WO2010019271A1 (en) 2010-02-18
US20110152339A1 (en) 2011-06-23
ATE547403T1 (de) 2012-03-15
BRPI0917411A2 (pt) 2015-12-01
JP2014148545A (ja) 2014-08-21
EP2323982B1 (en) 2012-02-29
AU2009282451B2 (en) 2014-02-13
EP2323982A1 (en) 2011-05-25
EP2484666A1 (en) 2012-08-08
CN102186820B (zh) 2013-08-28
AU2009282451A1 (en) 2010-02-18

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