JP2012244993A5 - - Google Patents

Download PDF

Info

Publication number
JP2012244993A5
JP2012244993A5 JP2012119327A JP2012119327A JP2012244993A5 JP 2012244993 A5 JP2012244993 A5 JP 2012244993A5 JP 2012119327 A JP2012119327 A JP 2012119327A JP 2012119327 A JP2012119327 A JP 2012119327A JP 2012244993 A5 JP2012244993 A5 JP 2012244993A5
Authority
JP
Japan
Prior art keywords
composition
daclizumab
dac hyp
administered
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012119327A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012244993A (ja
JP6055615B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2012244993A publication Critical patent/JP2012244993A/ja
Publication of JP2012244993A5 publication Critical patent/JP2012244993A5/ja
Application granted granted Critical
Publication of JP6055615B2 publication Critical patent/JP6055615B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012119327A 2011-05-27 2012-05-25 Dachyp組成物および方法 Expired - Fee Related JP6055615B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161490998P 2011-05-27 2011-05-27
US61/490,998 2011-05-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016161679A Division JP2016210796A (ja) 2011-05-27 2016-08-22 Dac hyp組成物および方法

Publications (3)

Publication Number Publication Date
JP2012244993A JP2012244993A (ja) 2012-12-13
JP2012244993A5 true JP2012244993A5 (https=) 2015-04-09
JP6055615B2 JP6055615B2 (ja) 2016-12-27

Family

ID=46177353

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2012119327A Expired - Fee Related JP6055615B2 (ja) 2011-05-27 2012-05-25 Dachyp組成物および方法
JP2016161679A Pending JP2016210796A (ja) 2011-05-27 2016-08-22 Dac hyp組成物および方法
JP2018073025A Pending JP2018134091A (ja) 2011-05-27 2018-04-05 Dac hyp組成物および方法
JP2020034673A Withdrawn JP2020078348A (ja) 2011-05-27 2020-03-02 Dac hyp組成物および方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2016161679A Pending JP2016210796A (ja) 2011-05-27 2016-08-22 Dac hyp組成物および方法
JP2018073025A Pending JP2018134091A (ja) 2011-05-27 2018-04-05 Dac hyp組成物および方法
JP2020034673A Withdrawn JP2020078348A (ja) 2011-05-27 2020-03-02 Dac hyp組成物および方法

Country Status (10)

Country Link
US (7) US20120301429A1 (https=)
EP (1) EP2527429A3 (https=)
JP (4) JP6055615B2 (https=)
CN (2) CN107090040A (https=)
AU (4) AU2012203095B2 (https=)
BR (1) BR102012012673A8 (https=)
CA (1) CA2777978A1 (https=)
MX (1) MX339533B (https=)
RU (2) RU2661764C2 (https=)
SG (1) SG185920A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6055615B2 (ja) 2011-05-27 2016-12-27 アッヴィ バイオテクノロジー リミテッド Dachyp組成物および方法
CA2844662A1 (en) 2011-08-08 2013-02-14 Abbvie Biotherapeutics Inc. Methods of treating progressive forms of multiple sclerosis
US20140295497A1 (en) * 2011-11-30 2014-10-02 Taymar E. Hartman Vectors and host cells comprising a modified sv40 promoter for protein expression
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
CN105518020A (zh) 2013-09-04 2016-04-20 Emd密理博公司 清洗基于a蛋白的亲和色谱柱的方法
GB201503578D0 (en) * 2015-03-03 2015-04-15 Ge Healthcare Bio Sciences Ab Sanitization method for affinity chromatography matrices
JP7133925B2 (ja) * 2015-03-23 2022-09-09 アレクシオン ファーマシューティカルズ インコーポレイテッド ウイルス濾過
RU2021101009A (ru) 2015-08-12 2021-02-20 Пфайзер Инк. Кэпированные и некэпированные цистеины антитела, и их применение в конъюгации антитело - лекарственное средство
US11261462B2 (en) 2016-01-27 2022-03-01 Just-Evotec Biologics, Inc. Inducible expression from transposon-based vectors and uses
US11098310B2 (en) 2016-01-27 2021-08-24 Just-Evotec Biologics, Inc. Expression from transposon-based vectors and uses
JP6937309B2 (ja) 2016-01-27 2021-09-22 ジャスト−エヴォテック バイオロジックス、インコーポレイテッド ハイブリッドプロモーターおよびその使用
WO2018027195A1 (en) * 2016-08-05 2018-02-08 Abbvie Biotherapeutics Inc. Compositions containing reduced amounts of daclizumab acidic isoforms and methods for preparing the same
AU2018212974B2 (en) * 2017-01-30 2023-08-24 Regeneron Pharmaceuticals, Inc. Compositions and methods for reducing bioburden in chromatography
KR102753090B1 (ko) * 2017-12-21 2025-01-14 젠자임 코포레이션 단백질 a 크로마토그래피 동안 불순물의 향상된 제거를 위한 방법
WO2020214792A1 (en) * 2019-04-17 2020-10-22 Bristol-Myers Squibb Company Methods for regenerating chromatography resins
KR102731889B1 (ko) * 2019-07-18 2024-11-19 에이비온 주식회사 2당화된 인터페론-베타 단백질의 정제 방법
CA3146209A1 (en) * 2019-08-01 2021-02-04 John MATTILA Method for viral inactivation
SG11202110968VA (en) 2019-12-06 2021-10-28 Regeneron Pharma Anti-vegf protein compositions and methods for producing the same
AU2021268026A1 (en) 2020-05-08 2023-01-19 Regeneron Pharmaceuticals, Inc. VEGF traps and mini-traps and methods for treating ocular disorders and cancer
JP7631742B2 (ja) * 2020-11-10 2025-02-19 東ソー株式会社 ペプチド性リガンド固定化カラムの洗浄方法
EP4334356A1 (en) * 2021-05-03 2024-03-13 Boehringer Ingelheim International Gmbh Method for producing spesolimab
CN114181300A (zh) * 2021-12-20 2022-03-15 方坦思(上海)生物医药有限公司 一种高纯度单克隆抗体的制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1430566A (en) * 1974-11-15 1976-03-31 Nestel Sa Isolation of proteins
US7442777B2 (en) * 2000-11-29 2008-10-28 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD63
RU2318537C2 (ru) * 2001-04-06 2008-03-10 Юниверсити Оф Бристоль Применение cd25-связывающих молекул для лечения пациентов, устойчивых к стероидам
JP2005325133A (ja) * 2001-10-15 2005-11-24 Kirin Brewery Co Ltd 抗hla−dr抗体の利用
US20040002135A1 (en) * 2002-03-28 2004-01-01 Sauer Paul W. Adapted NS0 cell lines with the ability to grow under glutamine-free conditions
US7365168B2 (en) * 2002-10-15 2008-04-29 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
JPWO2004087761A1 (ja) * 2003-03-31 2006-07-27 麒麟麦酒株式会社 ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製
US20070190057A1 (en) 2006-01-23 2007-08-16 Jian Wu Methods for modulating mannose content of recombinant proteins
WO2007146847A2 (en) 2006-06-09 2007-12-21 University Of Maryland, Baltimore Glycosylation engineered antibody therapy
JP2010510963A (ja) * 2006-06-14 2010-04-08 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー セラミックヒドロキシアパタイトを使用する抗体の精製方法
WO2008004931A1 (en) * 2006-07-06 2008-01-10 Ge Healthcare Bio-Sciences Ab Disinfection/sanitation method where the material is treated with a solution comprising benzyl alcohol and c2-3 alcohol
JP2011512875A (ja) * 2008-03-11 2011-04-28 ジェネンテック, インコーポレイテッド 増強されたadcc機能を有する抗体
RU2011111391A (ru) * 2008-08-28 2012-10-10 Эбботт Байотерапьютикс Корп. (Us) Способ лечения пациентов, страдающих рассеянным склерозом, антителами анти-il2r
US20120329709A1 (en) * 2009-05-26 2012-12-27 Brian Edward Collins Production of glycoproteins
CA2763164A1 (en) 2009-06-05 2010-12-09 Momenta Pharmaceuticals, Inc. Methods of modulating fucosylation of glycoproteins
EP2462157B1 (en) * 2009-08-07 2020-06-17 EMD Millipore Corporation Methods for purifying a target protein from one or more impurities in a sample
US20110053223A1 (en) 2009-08-14 2011-03-03 Robert Bayer Cell culture methods to make antibodies with enhanced adcc function
US10087236B2 (en) * 2009-12-02 2018-10-02 Academia Sinica Methods for modifying human antibodies by glycan engineering
CA3253628A1 (en) 2010-03-05 2025-11-29 The Johns Hopkins University Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
JP6055615B2 (ja) * 2011-05-27 2016-12-27 アッヴィ バイオテクノロジー リミテッド Dachyp組成物および方法

Similar Documents

Publication Publication Date Title
JP2012244993A5 (https=)
RU2018119112A (ru) Композиции и способы на основе dac hyp
EP2964674B1 (en) Anti-tnf-anti-il-17 bispecific antibodies
TW516962B (en) A human TNFR1-IgG1 preparation
US20080167450A1 (en) Methods of purifying proteins
KR20120100914A (ko) 에프라투주맙을 이용한 자가면역 및 염증 질환의 치료
AU2017206006B2 (en) Modulation of afucosylated species in a monoclonal antibody composition
MX2014000093A (es) Composiciones del polipéptido de fusión tnfr: fc exentas de argina y métodos de uso.
JP6514789B2 (ja) 新規組換え抗TNF−αキメラモノクローナル抗体の製造方法及び用途
WO2013166099A1 (en) Novel antibodies
US20190048070A1 (en) Reduction of high molecular weight species, acidic charge species and fragments in a monoclonal antibody composition
EP3101035A1 (en) Bifunctional fusion protein, preparation method therefor, and use thereof
CN107208081B (zh) 用于从包含污染宿主细胞蛋白质的材料纯化重组人α-半乳糖苷酶A的方法
WO2017038986A1 (ja) 組換えタンパク質の製造方法
TWI891671B (zh) 血清白蛋白與生長激素之融合蛋白質之製造方法
HK40091815A (zh) 一种由基因组被编辑的cho宿主细胞产生的具有独特糖谱的重组抗体及其制备方法
HK40091814A (zh) 一种由基因组被编辑的cho宿主细胞产生的具有独特糖谱的重组抗体及其制备方法
HK1241916A1 (en) Method for purification of recombinant human alpha-galactosidase a from material containing contaminant host cell proteins