JP2012161635A5 - - Google Patents

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JP2012161635A5
JP2012161635A5 JP2012095395A JP2012095395A JP2012161635A5 JP 2012161635 A5 JP2012161635 A5 JP 2012161635A5 JP 2012095395 A JP2012095395 A JP 2012095395A JP 2012095395 A JP2012095395 A JP 2012095395A JP 2012161635 A5 JP2012161635 A5 JP 2012161635A5
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Japan
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JP2012095395A
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JP2012161635A (ja
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Priority claimed from US08/822,186 external-priority patent/US7041641B2/en
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JP2012095395A 1997-03-20 2012-04-19 骨の修復のための骨形成デバイスおよびその使用 Pending JP2012161635A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/822,186 1997-03-20
US08/822,186 US7041641B2 (en) 1997-03-20 1997-03-20 Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects

Related Parent Applications (1)

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JP2009040036A Division JP2009131649A (ja) 1997-03-20 2009-02-23 骨の修復のための骨形成デバイスおよびその使用

Related Child Applications (1)

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JP2014168198A Division JP2014221427A (ja) 1997-03-20 2014-08-21 骨の修復のための骨形成デバイスおよびその使用

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JP2012161635A JP2012161635A (ja) 2012-08-30
JP2012161635A5 true JP2012161635A5 (ja) 2013-02-14

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JP54086898A Expired - Fee Related JP4477702B2 (ja) 1997-03-20 1998-03-20 骨の修復のための骨形成デバイスおよびその使用
JP2009040036A Ceased JP2009131649A (ja) 1997-03-20 2009-02-23 骨の修復のための骨形成デバイスおよびその使用
JP2012095395A Pending JP2012161635A (ja) 1997-03-20 2012-04-19 骨の修復のための骨形成デバイスおよびその使用
JP2014168198A Withdrawn JP2014221427A (ja) 1997-03-20 2014-08-21 骨の修復のための骨形成デバイスおよびその使用

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JP54086898A Expired - Fee Related JP4477702B2 (ja) 1997-03-20 1998-03-20 骨の修復のための骨形成デバイスおよびその使用
JP2009040036A Ceased JP2009131649A (ja) 1997-03-20 2009-02-23 骨の修復のための骨形成デバイスおよびその使用

Family Applications After (1)

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JP2014168198A Withdrawn JP2014221427A (ja) 1997-03-20 2014-08-21 骨の修復のための骨形成デバイスおよびその使用

Country Status (11)

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US (3) US7041641B2 (ja)
EP (3) EP1719531A3 (ja)
JP (4) JP4477702B2 (ja)
AT (1) ATE338569T1 (ja)
AU (1) AU751451B2 (ja)
CA (1) CA2284098C (ja)
DE (1) DE69835810T2 (ja)
DK (1) DK0968012T3 (ja)
ES (1) ES2273412T3 (ja)
PT (1) PT968012E (ja)
WO (1) WO1998041246A2 (ja)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919308B2 (en) * 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US20080233170A1 (en) * 1992-02-21 2008-09-25 Stryker Corporation Osteogenic Proteins
US7041641B2 (en) * 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
US20010016646A1 (en) * 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US6391336B1 (en) * 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
ES2478257T3 (es) * 1998-10-06 2014-07-21 Stryker Corporation Composición que comprende una proteína osteogénica seleccionada del grupo que consiste en OP-2, OP-3, BMP-2, BMP-3, BMP-4, BMP-5, BMP-6, BMP-9, BMP-10, BMP-11 , BMP-15, BMP-3B, DPP, Vg-1, Vgr-1, proteína 60A, GDF-1, GDF-2, GDF-3, GDF-6, GDF-7, GDF-8, GDF-9, GDF-10, y GDF-11 para su uso en la reparación de defectos del cartílago no articular
US6958149B2 (en) * 1998-10-06 2005-10-25 Stryker Corporation Repair of larynx, trachea, and other fibrocartilaginous tissues
US7572440B2 (en) 1999-07-30 2009-08-11 Stryker Corporation Method for repairing a defect in an intervertebral disc
EP1025871A1 (en) * 1999-01-28 2000-08-09 F. Hoffmann-La Roche Ag Use of a melanoma inhibiting activity factor (MIA) for cartilage and bone repair
US7687462B2 (en) 1999-10-05 2010-03-30 The Regents Of The University Of California Composition for promoting cartilage formation or repair comprising a nell gene product and method of treating cartilage-related conditions using such composition
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
SI1365769T1 (sl) 2001-02-06 2011-06-30 Sydney Children S Hospitals Network Randwick And Westmead Incorporating The Royal Alexandra Hospital Zdravilo za zdravljenje osteonekroze za oskrbo pacientov pri tveganju razvoja osteonekroze
US6949251B2 (en) * 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
JP2005516972A (ja) * 2002-01-22 2005-06-09 ファイザー・インク 血栓疾患の治療のためのｔａｆｉ−ａ阻害剤として使用される３−（イミダゾリル）−２−アミノプロピオン酸
US7598224B2 (en) 2002-08-20 2009-10-06 Biosurface Engineering Technologies, Inc. Dual chain synthetic heparin-binding growth factor analogs
US7166574B2 (en) * 2002-08-20 2007-01-23 Biosurface Engineering Technologies, Inc. Synthetic heparin-binding growth factor analogs
US8227411B2 (en) * 2002-08-20 2012-07-24 BioSurface Engineering Technologies, Incle FGF growth factor analogs
US7582309B2 (en) 2002-11-15 2009-09-01 Etex Corporation Cohesive demineralized bone compositions
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) * 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
CA2536104A1 (en) * 2003-08-20 2005-03-03 Histogenics Corporation Acellular matrix implanted into an articular cartilage or osteochondral lesion protected with a biodegradable polymer modified to have extended polymerization time and methods forpreparation and use thereof
US20080227696A1 (en) * 2005-02-22 2008-09-18 Biosurface Engineering Technologies, Inc. Single branch heparin-binding growth factor analogs
CA2555583A1 (en) 2004-02-20 2005-09-09 Biosurface Engineering Technologies, Inc. Positive modulator of bone morphogenic protein-2
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060233849A1 (en) * 2005-04-13 2006-10-19 Simon Bruce J Composite bone graft material
US7621963B2 (en) * 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
JP2009508596A (ja) 2005-09-19 2009-03-05 ヒストジェニックス コーポレイション 細胞支持基材及びその調製方法
CA2630077C (en) * 2005-11-17 2014-07-15 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
WO2007092622A2 (en) * 2006-02-09 2007-08-16 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
US7820172B1 (en) 2006-06-01 2010-10-26 Biosurface Engineering Technologies, Inc. Laminin-derived multi-domain peptides
EP2046350A4 (en) 2006-06-22 2011-09-14 Biosurface Eng Tech Inc COMPOSITIONS AND METHOD FOR THE RELEASE OF A BMP-2 AMPLIFIER / COACTIVATOR FOR REINFORCED OSTEOGENESIS
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
ES2664229T3 (es) 2006-06-30 2018-04-18 Biomimetic Therapeutics, Llc Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador
US20060287654A1 (en) * 2006-08-11 2006-12-21 Jeffrey Posnick Implant securing device and method
US7468048B2 (en) 2006-10-06 2008-12-23 National Jewish Health Joint aspirate facilitating device
EP2086598B1 (en) 2006-11-03 2015-05-27 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
US20080125863A1 (en) * 2006-11-28 2008-05-29 Mckay William F Implant designs and methods of improving cartilage repair
AU2007234612B2 (en) * 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
US20080154372A1 (en) * 2006-12-21 2008-06-26 Peckham Steven M Osteochondral implant using a growth factor concentration gradient for repair of bone and cartilage tissue
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
WO2009131553A2 (en) 2006-12-29 2009-10-29 Osteogenex Inc. Methods of altering bone growth by administration of sost or wise antagonist or agonist
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US8431148B2 (en) 2007-03-08 2013-04-30 Warsaw Orthopedic, Inc. Bone void filler
ES2381448T3 (es) * 2007-03-26 2012-05-28 Baxter International Inc. Material de relleno de huecos inyectable par el aumento de tejidos blandos
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
JP5323832B2 (ja) 2007-08-07 2013-10-23 アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー 酸性水溶液中にｇｄｆ−５を含むタンパク質製剤
US20090054906A1 (en) * 2007-08-24 2009-02-26 Zimmer Orthobiologics, Inc. Medical device and method for delivering an implant to an anatomical site
JP4596335B2 (ja) 2007-12-07 2010-12-08 東洋紡績株式会社 神経再生誘導管の製造方法
ES2422259T3 (es) * 2008-02-07 2013-09-10 Biomimetic Therapeutics Inc Composiciones para la osteogénesis por distracción
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8685432B2 (en) * 2008-03-25 2014-04-01 University Of Utah Research Foundation Controlled release tissue graft combination biomaterials
CA2720845A1 (en) * 2008-04-14 2009-10-22 Advanced Technologies And Regenerative Medicine, Llc Liquid buffered gdf-5 formulations
EA018602B1 (ru) * 2008-08-25 2013-09-30 Лазер Абразив Техноложес, Ллс Способ и устройство для регенерации тканей полости рта
NZ591338A (en) 2008-09-09 2013-02-22 Biomimetic Therapeutics Inc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US20100145451A1 (en) 2008-12-04 2010-06-10 Derek Dee Joint support and subchondral support system
US10610364B2 (en) 2008-12-04 2020-04-07 Subchondral Solutions, Inc. Method for ameliorating joint conditions and diseases and preventing bone hypertrophy
US9320761B2 (en) 2008-12-18 2016-04-26 Vivex Biomedical, Inc. Bone induction system and methods
US20100247651A1 (en) * 2009-03-05 2010-09-30 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects
US10806833B1 (en) 2009-05-11 2020-10-20 Integra Lifesciences Corporation Adherent resorbable matrix
AU2010258931B2 (en) 2009-06-08 2015-04-23 Acceleron Pharma Inc. Methods for increasing thermogenic adipocytes
DE102009024616A1 (de) 2009-06-08 2010-12-23 Telos Gmbh Sterilisierbare Implantatbeschichtung und Verfahren zu deren Herstellung
US8293881B2 (en) 2009-06-12 2012-10-23 Acceleron Pharma Inc. Isolated nucleic acid encoding a truncated ActRIIB fusion protein
WO2011031637A2 (en) * 2009-09-08 2011-03-17 Musculoskeletal Transplant Foundation Inc. Tissue engineered meniscus repair composition
WO2011031642A2 (en) * 2009-09-08 2011-03-17 Musculoskeletal Transplant Foundation Inc. Tissue engineered meniscus repair composition
EP2352750B1 (en) 2009-09-17 2012-06-13 Stryker Corporation Buffers for controlling the ph of bone morphogenetic proteins
US8801800B2 (en) 2009-11-20 2014-08-12 Zimmer Knee Creations, Inc. Bone-derived implantable devices and tool for subchondral treatment of joint pain
KR20120132469A (ko) * 2009-11-20 2012-12-05 니 크리에이션스, 엘엘씨 관절 치료를 위한 좌표 맵핑 시스템
US8821504B2 (en) 2009-11-20 2014-09-02 Zimmer Knee Creations, Inc. Method for treating joint pain and associated instruments
US8951261B2 (en) 2009-11-20 2015-02-10 Zimmer Knee Creations, Inc. Subchondral treatment of joint pain
US8608802B2 (en) 2009-11-20 2013-12-17 Zimmer Knee Creations, Inc. Implantable devices for subchondral treatment of joint pain
JP2013511358A (ja) 2009-11-20 2013-04-04 ニー・クリエイションズ・リミテッド・ライアビリティ・カンパニー 関節修復のためのナビゲーションおよび位置決め機器
KR20120112470A (ko) 2009-11-20 2012-10-11 니 크리에이션스, 엘엘씨 관절 결함을 표적화하기 위한 기기
JP2013511356A (ja) 2009-11-20 2013-04-04 ニー・クリエイションズ・リミテッド・ライアビリティ・カンパニー 関節に可変角度接近するための装置
JP2013514811A (ja) 2009-12-22 2013-05-02 ストライカー コーポレイション 免疫原性が抑制されたｂｍｐ−７変異体
EP2523672B1 (en) 2010-01-15 2016-07-13 Rutgers, the State University of New Jersey Use of vanadium compounds to accelerate bone healing
WO2011103598A1 (en) 2010-02-22 2011-08-25 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
WO2011153512A2 (en) * 2010-06-03 2011-12-08 Indiana University Research And Technology Corporation Use of compounds with thrombopoietic activity to promote bone growth and healing
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
CN103313733A (zh) 2010-11-15 2013-09-18 捷迈整形外科生物材料有限公司 骨空隙填充剂
US20140322292A1 (en) 2010-12-10 2014-10-30 Rutgers, The State University Of New Jersey Insulin-mimetics as therapeutic adjuncts for bone regeneration
WO2013006798A1 (en) 2011-07-06 2013-01-10 University Of Medicine And Dentistry Of New Jersey Vandium compounds as therapeutic adjuncts for cartilage regeneration and repair
KR20140048076A (ko) 2010-12-10 2014-04-23 유니버시티 오브 메디신 앤드 덴티스트리 오브 뉴 저지 인슐린 모사 제제 복합재로 코팅된 생체 매립가능한 장치 및 이의 방법
EP2529764A1 (de) 2011-05-31 2012-12-05 Curasan AG Biologisch degradierbares kompositmaterial
PL2758087T3 (pl) * 2011-10-21 2018-12-31 Nitta Casings Inc. Materiały kolagenowo-polisacharydowe imitujące naczynia krwionośne, tkanki i kości
US10207027B2 (en) 2012-06-11 2019-02-19 Globus Medical, Inc. Bioactive bone graft substitutes
EP2953581B1 (en) 2013-02-05 2020-09-16 University of Utah Research Foundation Implantable devices for bone or joint defects
CA2899247C (en) 2013-03-14 2023-04-04 Osteoqc Inc. Alkyl-amine harmine derivatives for promoting bone growth
US9486483B2 (en) 2013-10-18 2016-11-08 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9539286B2 (en) 2013-10-18 2017-01-10 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9579421B2 (en) 2014-02-07 2017-02-28 Globus Medical Inc. Bone grafts and methods of making and using bone grafts
US9463264B2 (en) 2014-02-11 2016-10-11 Globus Medical, Inc. Bone grafts and methods of making and using bone grafts
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US10130678B2 (en) 2014-12-29 2018-11-20 Bioventus, LLC. Systems and methods for improved delivery of osteoinductive molecules in bone repair
US10016529B2 (en) 2015-06-10 2018-07-10 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US11426489B2 (en) 2015-06-10 2022-08-30 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US11039927B2 (en) 2015-11-25 2021-06-22 Subchondral Solutions, Inc. Methods, systems and devices for repairing anatomical joint conditions
WO2017203331A1 (en) 2016-05-27 2017-11-30 Universität Bern Composition and methods for bone tissue engineering
JP2019076077A (ja) * 2017-10-23 2019-05-23 株式会社 東亜産業 非タバコ植物を用いた電子タバコカートリッジ用充填物の製造方法
CA3109104A1 (en) 2018-08-14 2020-02-20 Osteoqc Inc. Fluoro .beta.-carboline compounds
CA3108714A1 (en) 2018-08-14 2020-02-20 Osteoqc Inc. Pyrrolo - dipyridine compounds
WO2020118011A1 (en) 2018-12-06 2020-06-11 Alexion Pharmaceuticals, Inc. Anti-alk2 antibodies and uses thereof
US11896736B2 (en) 2020-07-13 2024-02-13 Globus Medical, Inc Biomaterial implants and methods of making the same

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153739A (en) * 1977-06-30 1979-05-08 Becton, Dickinson And Company Method for collecting blood
US4353982A (en) * 1980-04-10 1982-10-12 Hoffmann-La Roche Inc. Immunochemical assay for creatine kinase-MB isoenzyme
FR2559666B1 (fr) * 1984-02-21 1986-08-08 Tech Cuir Centre Procede de fabrication de tubes de collagene, notamment de tubes de faibles diametres, et application des tubes obtenus dans le domaine des protheses vasculaires et des sutures nerveuses
IL83003A (en) 1986-07-01 1995-07-31 Genetics Inst Factors that soak bone formation
WO1990011366A1 (en) 1989-03-28 1990-10-04 Genetics Institute, Inc. Osteoinductive compositions
US5013649A (en) 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
JPS63181770A (ja) 1987-01-21 1988-07-26 永瀬　守 リン酸三カルシウムと酸と蛋白質と水を混合する事により硬化生成した人工骨
US5457093A (en) 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
DE01201546T1 (de) 1988-04-08 2004-07-08 Stryker Corp., Kalamazoo Osteogene Einrichtungen
US4975526A (en) 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US5354557A (en) 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US4968590A (en) 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
US5266683A (en) 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US5284756A (en) * 1988-10-11 1994-02-08 Lynn Grinna Heterodimeric osteogenic factor
US5013714A (en) * 1988-12-15 1991-05-07 Lindstrom Richard L Viscoelastic solution
JP2877840B2 (ja) 1989-06-08 1999-04-05 三金工業株式会社 生体硬組織用セメント材料
US5422340A (en) * 1989-09-01 1995-06-06 Ammann; Arthur J. TGF-βformulation for inducing bone growth
US5073373A (en) * 1989-09-21 1991-12-17 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
EP0536186B1 (en) 1990-05-16 2001-11-21 Genetics Institute, Inc. Bone and cartilage inductive proteins
US5645591A (en) * 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
ES2137931T3 (es) 1990-06-15 2000-01-01 Carnegie Inst Of Washington Proteinas gdf-1 y uog-1.
US5853746A (en) * 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
MX9203083A (es) 1991-06-21 1994-08-31 Genetics Inst Formulaciones farmaceuticas de proteinas osteogenicas.
DK0592562T3 (da) 1991-06-25 1999-08-30 Genetics Inst BMP-9-præparater
US6287816B1 (en) 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
IT1259042B (it) * 1992-01-27 1996-03-11 Mini Ricerca Scient Tecnolog Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
US5281265A (en) * 1992-02-03 1994-01-25 Liu Sung Tsuen Resorbable surgical cements
ATE188996T1 (de) 1992-02-12 2000-02-15 Bioph Biotech Entw Pharm Gmbh Dna-sequenzen kodierend für neuartige wachstums- /differentierungsfaktoren
JPH08503198A (ja) 1992-11-03 1996-04-09 クリエイティブ バイオモレキュルズ，インコーポレイテッド Ｏｐ−３誘導形態形成
DE4240621A1 (de) 1992-12-03 1994-06-09 Zahnradfabrik Friedrichshafen Verfahren zur Steuerung und Regelung der Lastübernahme bei einem automatischen Schaltgetriebe
US6232458B1 (en) * 1992-12-22 2001-05-15 The University Of Sydney Synthetic polynucleotides encoding tropoelastin
CA2151486A1 (en) 1993-01-12 1994-07-21 Arthur J. Ammann Tgf-beta formulation for inducing bone growth
EP0678101A4 (en) 1993-01-12 1997-07-16 Univ Johns Hopkins Med GROWTH DIFFERENTIATION FACTOR-9.
EP0679163A4 (en) 1993-01-12 1997-07-16 Univ Johns Hopkins Med FACTOR-3 OF GROWTH AND DIFFERENTIATION.
EP0690871A4 (en) 1993-01-12 1999-10-20 Univ Johns Hopkins Med GROWTH AND DIFFERENTIATION FACTOR-5
WO1994020133A1 (en) 1993-03-12 1994-09-15 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
EP1333035A3 (en) 1993-03-19 2004-07-07 The Johns Hopkins University School Of Medicine Growth differentiation factor-8
CA2161808C (en) 1993-05-12 2008-08-05 Anthony J. Celeste Bmp-11 compositions
CA2161807A1 (en) 1993-05-12 1994-11-24 Anthony J. Celeste Bmp-10 compositions
JPH09503903A (ja) 1993-07-09 1997-04-22 ザ ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 増殖分化因子−６
EP0717633A4 (en) 1993-07-09 1998-05-20 Univ Johns Hopkins Med GROWTH DIFFERENTIATION FACTOR-7
US5385887A (en) 1993-09-10 1995-01-31 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
WO1995010539A1 (en) 1993-10-08 1995-04-20 The Johns Hopkins University School Of Medicine Growth differentiation factor-10
JP3300500B2 (ja) 1993-10-12 2002-07-08 新日本製鐵株式会社 疲労強度、降伏強度および被削性に優れる熱間鍛造用鋼の製造方法
DE4334646C1 (de) 1993-10-12 1994-09-29 Quinting Friedhelm Durchsichtige Analog-Zeituhr
AU689184B2 (en) 1993-12-07 1998-03-26 Genetics Institute, Llc BMP-12, BMP-13 and tendon-inducing compositions thereof
US5587897A (en) 1993-12-27 1996-12-24 Nec Corporation Optimization device
FR2715853B1 (fr) * 1994-02-08 1996-04-26 Centre Nat Rech Scient Composition pour bio-matériau; procédé de préparation.
JP3011006B2 (ja) 1994-02-16 2000-02-21 豊田合成株式会社 ポリオレフィン樹脂成形物の表面改質方法及びその表面塗装方法
WO1995024210A1 (en) 1994-03-08 1995-09-14 Genetics Institute, Inc. Methods and compositions for treatment of periodontal disease and repair of periodontal lesions
JP3424049B2 (ja) 1994-03-09 2003-07-07 山之内製薬株式会社 骨形成用移植体
JPH09510461A (ja) 1994-03-24 1997-10-21 ベーリンガー インゲルハイム アグロベット アー／エス 薬剤又は栄養剤を動物に投与するための粒状生成物を含む投薬ユニット及び粒状生成物の製造方法
IL114397A0 (en) 1994-07-01 1995-10-31 Bioph Biotech Entw Pharm Gmbh Growth/differentiation factor of the TGF-beta-family
ES2251721T3 (es) 1994-07-08 2006-05-01 The Johns Hopkins University School Of Medicine Factor-11 de diferenciacion del crecimiento.
US5520923A (en) 1994-09-19 1996-05-28 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
WO1996014335A1 (en) 1994-11-07 1996-05-17 The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Health And Human Services Cartilage-derived morphogenetic proteins
FI952196A0 (fi) 1995-05-08 1995-05-08 Suomen Punainen Risti Veripalv Framstaellning av immunoglobulin
US5635372A (en) 1995-05-18 1997-06-03 Genetics Institute, Inc. BMP-15 compositions
EP1364656B1 (en) 1995-06-05 2013-11-20 Genetics Institute, LLC Use of bone morphogenetic proteins for healing and repair of connective tissue attachment
US5902785A (en) 1995-06-06 1999-05-11 Genetics Institute, Inc. Cartilage induction by bone morphogenetic proteins
US5674292A (en) * 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
US7041641B2 (en) * 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
US6949251B2 (en) * 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue

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