JP2012073268A5 - - Google Patents
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- JP2012073268A5 JP2012073268A5 JP2011256171A JP2011256171A JP2012073268A5 JP 2012073268 A5 JP2012073268 A5 JP 2012073268A5 JP 2011256171 A JP2011256171 A JP 2011256171A JP 2011256171 A JP2011256171 A JP 2011256171A JP 2012073268 A5 JP2012073268 A5 JP 2012073268A5
- Authority
- JP
- Japan
- Prior art keywords
- flow
- stream
- cell
- cells
- separating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims description 55
- 238000004611 spectroscopical analysis Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 6
- 238000005286 illumination Methods 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- 238000003384 imaging method Methods 0.000 claims description 4
- 238000007689 inspection Methods 0.000 claims description 3
- 230000003595 spectral effect Effects 0.000 claims description 3
- 206010028980 Neoplasm Diseases 0.000 claims description 2
- 210000001766 X chromosome Anatomy 0.000 claims description 2
- 210000002593 Y chromosome Anatomy 0.000 claims description 2
- 210000000601 blood cell Anatomy 0.000 claims description 2
- 201000011510 cancer Diseases 0.000 claims description 2
- 238000000799 fluorescence microscopy Methods 0.000 claims description 2
- 230000003287 optical effect Effects 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 8
- 230000001413 cellular effect Effects 0.000 claims 6
- 238000000926 separation method Methods 0.000 claims 6
- 239000012530 fluid Substances 0.000 claims 2
- 238000002955 isolation Methods 0.000 claims 2
- 238000004062 sedimentation Methods 0.000 claims 2
- 210000003850 cellular structure Anatomy 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 239000012620 biological material Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000004940 nucleus Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 238000000701 chemical imaging Methods 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- -1 drainage Substances 0.000 description 1
- 238000002296 dynamic light scattering Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
- 238000000790 scattering method Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000002235 transmission spectroscopy Methods 0.000 description 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49995703P | 2003-09-04 | 2003-09-04 | |
| US60/499,957 | 2003-09-04 | ||
| US51145803P | 2003-10-15 | 2003-10-15 | |
| US60/511,458 | 2003-10-15 | ||
| US57114104P | 2004-05-14 | 2004-05-14 | |
| US60/571,141 | 2004-05-14 | ||
| US10/867,328 US7150834B2 (en) | 2003-07-31 | 2004-06-13 | Multiple laminar flow-based rate zonal or isopycnic separation with holographic optical trapping of blood cells and other static components |
| US10/867,328 | 2004-06-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006525516A Division JP5046645B2 (ja) | 2003-09-04 | 2004-09-03 | 血液や細胞等の液体混合物を構成成分に分離する方法、装置およびシステム。 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015091320A Division JP6154425B2 (ja) | 2003-09-04 | 2015-04-28 | 流体混合物における複数の細胞から少なくとも１つの細胞を同定し区別する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012073268A JP2012073268A (ja) | 2012-04-12 |
| JP2012073268A5 true JP2012073268A5 (enExample) | 2013-05-09 |
| JP5789178B2 JP5789178B2 (ja) | 2015-10-07 |
Family
ID=52347979
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006525516A Expired - Fee Related JP5046645B2 (ja) | 2003-09-04 | 2004-09-03 | 血液や細胞等の液体混合物を構成成分に分離する方法、装置およびシステム。 |
| JP2010256249A Expired - Fee Related JP5160622B2 (ja) | 2003-09-04 | 2010-11-16 | 粒子または細胞を配列する装置およびその方法 |
| JP2011200448A Expired - Fee Related JP5250674B2 (ja) | 2003-09-04 | 2011-09-14 | 粒子を精製・選別する装置およびその方法 |
| JP2011256171A Expired - Fee Related JP5789178B2 (ja) | 2003-09-04 | 2011-11-24 | レーザ操縦を用いた多層流に基づく粒子及び細胞の分離 |
| JP2015091320A Expired - Fee Related JP6154425B2 (ja) | 2003-09-04 | 2015-04-28 | 流体混合物における複数の細胞から少なくとも１つの細胞を同定し区別する方法 |
| JP2016185743A Expired - Lifetime JP6592414B2 (ja) | 2003-09-04 | 2016-09-23 | 流体混合物における複数の成分から少なくとも１つの成分を同定し区別する装置および方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006525516A Expired - Fee Related JP5046645B2 (ja) | 2003-09-04 | 2004-09-03 | 血液や細胞等の液体混合物を構成成分に分離する方法、装置およびシステム。 |
| JP2010256249A Expired - Fee Related JP5160622B2 (ja) | 2003-09-04 | 2010-11-16 | 粒子または細胞を配列する装置およびその方法 |
| JP2011200448A Expired - Fee Related JP5250674B2 (ja) | 2003-09-04 | 2011-09-14 | 粒子を精製・選別する装置およびその方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015091320A Expired - Fee Related JP6154425B2 (ja) | 2003-09-04 | 2015-04-28 | 流体混合物における複数の細胞から少なくとも１つの細胞を同定し区別する方法 |
| JP2016185743A Expired - Lifetime JP6592414B2 (ja) | 2003-09-04 | 2016-09-23 | 流体混合物における複数の成分から少なくとも１つの成分を同定し区別する装置および方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1663460B1 (enExample) |
| JP (6) | JP5046645B2 (enExample) |
| TW (1) | TW200523534A (enExample) |
| WO (1) | WO2005023391A2 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11243494B2 (en) | 2002-07-31 | 2022-02-08 | Abs Global, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
| CA2517208C (en) | 2003-02-26 | 2008-06-03 | Enventure Global Technology | Apparatus for radially expanding and plastically deforming a tubular member |
| WO2009035623A1 (en) * | 2007-09-11 | 2009-03-19 | Arryx, Inc. | Binding method and apparatus for sorting objects |
| JP2010538644A (ja) * | 2007-09-13 | 2010-12-16 | アリックス インク | 法医学的ｄｎａ分析および医学的診断において対象物を選別するための方法および装置 |
| US9364831B2 (en) | 2009-08-08 | 2016-06-14 | The Regents Of The University Of California | Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting |
| EP3708674B1 (en) * | 2010-11-16 | 2023-06-07 | 1087 Systems, Inc. | System for identifying and sorting living cells |
| US8941062B2 (en) | 2010-11-16 | 2015-01-27 | 1087 Systems, Inc. | System for identifying and sorting living cells |
| US20120225475A1 (en) | 2010-11-16 | 2012-09-06 | 1087 Systems, Inc. | Cytometry system with quantum cascade laser source, acoustic detector, and micro-fluidic cell handling system configured for inspection of individual cells |
| US10908066B2 (en) | 2010-11-16 | 2021-02-02 | 1087 Systems, Inc. | Use of vibrational spectroscopy for microfluidic liquid measurement |
| US9176504B2 (en) * | 2011-02-11 | 2015-11-03 | The Regents Of The University Of California | High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation |
| WO2013097870A1 (en) * | 2011-12-29 | 2013-07-04 | Danmarks Tekniske Universitet | System for sorting microscopic objects using electromagnetic radiation |
| WO2013128561A1 (ja) * | 2012-02-28 | 2013-09-06 | 株式会社メニコン | 細胞取扱用具 |
| US9545472B2 (en) * | 2012-03-02 | 2017-01-17 | Medtronic, Inc. | Extracorporeal blood circuit reservoir with angled venous inlet luer port |
| US10071359B2 (en) | 2013-03-15 | 2018-09-11 | The Regents Of The University Of California | High-speed on demand microfluidic droplet generation and manipulation |
| US8961904B2 (en) | 2013-07-16 | 2015-02-24 | Premium Genetics (Uk) Ltd. | Microfluidic chip |
| KR20150014781A (ko) | 2013-07-30 | 2015-02-09 | 삼성전자주식회사 | 유체를 여과하기 위한 장치 및 그를 이용한 입자를 분리하는 방법 |
| US11796449B2 (en) | 2013-10-30 | 2023-10-24 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| GB2528632A (en) * | 2014-04-30 | 2016-02-03 | Cambridge Entpr Ltd | Fluidic analysis and separation |
| LT3183568T (lt) | 2014-08-20 | 2023-01-25 | Stem Sel S.R.L. | Objektų frakcionavimo įrenginys ir frakcionavimo būdas |
| US11708556B2 (en) | 2014-10-20 | 2023-07-25 | University Of Utah Research Foundation | Tissue sample processing system and associated methods |
| FI3314123T3 (fi) * | 2015-06-23 | 2024-05-02 | Nanocellect Biomedical Inc | Järjestelmiä, laitteita ja menetelmiä solujen lajitteluun ja virtaussytometriaan |
| JP6762695B2 (ja) * | 2015-09-18 | 2020-09-30 | 浜松ホトニクス株式会社 | 流路装置 |
| WO2018080997A1 (en) * | 2016-10-24 | 2018-05-03 | Gpb Scientific, Llc | Deterministic lateral displacement in the preparation of cells and compositions for therapeutic uses |
| WO2018235634A1 (ja) * | 2017-06-21 | 2018-12-27 | 株式会社ニコン | 流体デバイス及びその使用 |
| EP3422364B1 (en) * | 2017-06-27 | 2019-12-11 | Medizinische Universität Graz | Method and device for analyzing a fluidic sample with dispersed particles |
| BR112020023607A2 (pt) | 2018-05-23 | 2021-02-17 | Abs Global, Inc. | sistemas e métodos para focalização de partículas em microcanais |
| JP7162330B2 (ja) * | 2018-07-11 | 2022-10-28 | 株式会社アタゴ | 粘度計 |
| JP2020082047A (ja) * | 2018-11-30 | 2020-06-04 | シスメックス株式会社 | 分離成否判定方法、粒子検出方法および粒子分離装置 |
| CN113498362B (zh) * | 2019-02-27 | 2023-01-20 | 京瓷株式会社 | 粒子分离测量设备以及粒子分离测量装置 |
| JP7212886B2 (ja) * | 2019-03-22 | 2023-01-26 | 国立研究開発法人産業技術総合研究所 | 受精用精子液の製造方法及び凍結精子ストローの製造方法 |
| EP4245140A3 (en) | 2019-04-18 | 2024-01-17 | ABS Global, Inc. | System and process for continuous addition of cryoprotectant |
| KR102266834B1 (ko) * | 2019-08-13 | 2021-06-17 | 경희대학교 산학협력단 | 정자 처리를 위한 미세유체장치 |
| US11628439B2 (en) | 2020-01-13 | 2023-04-18 | Abs Global, Inc. | Single-sheath microfluidic chip |
| US12345625B2 (en) | 2020-05-08 | 2025-07-01 | University Public Corporation Osaka | Microscopic object detection device, detection system, and detection method |
| JP2020157295A (ja) * | 2020-06-10 | 2020-10-01 | 浜松ホトニクス株式会社 | 流路装置 |
| JP7633402B2 (ja) | 2020-11-23 | 2025-02-19 | エイビーエス グローバル、インコーポレイテッド | モジュール式フロー・サイトメトリ・システム及びサンプル処理方法 |
| KR102763665B1 (ko) * | 2022-05-19 | 2025-02-06 | 단국대학교 산학협력단 | 정자 성별 분류장치 |
| KR102763666B1 (ko) * | 2022-05-26 | 2025-02-06 | 단국대학교 산학협력단 | 정자 성별 분류장치 |
| KR20240123023A (ko) * | 2023-02-06 | 2024-08-13 | 주식회사 그리니쉬 | 정자 선별 장치 및 정자 선별 방법 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5890513A (ja) * | 1981-11-26 | 1983-05-30 | Asahi Chem Ind Co Ltd | 血液成分の分取法および分取装置 |
| JPS57131451A (en) * | 1981-02-05 | 1982-08-14 | Asahi Chemical Ind | Method and apparatus for separating blood components |
| US4765899A (en) * | 1983-10-11 | 1988-08-23 | E. I. Du Pont De Nemours And Company | Apparatus for continuous separation of leukocyte/platelet-enriched fraction from whole blood |
| JP2777385B2 (ja) * | 1988-11-30 | 1998-07-16 | 株式会社日立製作所 | 生物細胞の培養方法，培養システム及び培養装置 |
| GB9003253D0 (en) * | 1990-02-13 | 1990-04-11 | Amersham Int Plc | Precipitating polymers |
| JPH0427866A (ja) * | 1990-05-23 | 1992-01-30 | Omron Corp | 細胞選別装置 |
| JPH0526799A (ja) * | 1991-07-19 | 1993-02-02 | Nippon Steel Corp | 微粒子の分離方法 |
| JPH0724309A (ja) * | 1993-07-08 | 1995-01-27 | Canon Inc | 粒子の分離方法及び装置 |
| US6797942B2 (en) * | 2001-09-13 | 2004-09-28 | University Of Chicago | Apparatus and process for the lateral deflection and separation of flowing particles by a static array of optical tweezers |
| US5716852A (en) * | 1996-03-29 | 1998-02-10 | University Of Washington | Microfabricated diffusion-based chemical sensor |
| WO1997000442A1 (en) * | 1995-06-16 | 1997-01-03 | The University Of Washington | Microfabricated differential extraction device and method |
| US5948684A (en) * | 1997-03-31 | 1999-09-07 | University Of Washington | Simultaneous analyte determination and reference balancing in reference T-sensor devices |
| EP0910474B1 (en) * | 1996-06-14 | 2004-03-24 | University of Washington | Absorption-enhanced differential extraction method |
| AU4113297A (en) * | 1996-09-04 | 1998-03-26 | Technical University Of Denmark | A micro flow system for particle separation and analysis |
| JP2001508869A (ja) * | 1997-01-08 | 2001-07-03 | ブリストル−マイヤーズ スクイブ カンパニー | 血液を分離するための遠心分離装置 |
| US6071689A (en) * | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
| DE19810195A1 (de) * | 1998-03-10 | 1999-09-23 | Reinhard Salinger | Verfahren und Vorrichtung zur Sammlung und Weiterverarbeitung von spezifischen Blutkomponenten bei kontinuierlichen laminaren Strömungsverhältnissen |
| CA2408939C (en) * | 2000-05-09 | 2011-11-08 | Xy, Inc. | High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa |
| US20030007894A1 (en) * | 2001-04-27 | 2003-01-09 | Genoptix | Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles |
| US20020160470A1 (en) * | 2000-11-13 | 2002-10-31 | Genoptix | Methods and apparatus for generating and utilizing linear moving optical gradients |
| WO2002093202A2 (en) * | 2001-05-14 | 2002-11-21 | Arryx, Inc. | Improved apparatus, system and method for applying optical gradient forces |
-
2004
- 2004-09-03 EP EP04783338.9A patent/EP1663460B1/en not_active Expired - Lifetime
- 2004-09-03 JP JP2006525516A patent/JP5046645B2/ja not_active Expired - Fee Related
- 2004-09-03 TW TW093126848A patent/TW200523534A/zh unknown
- 2004-09-03 WO PCT/US2004/029053 patent/WO2005023391A2/en not_active Ceased
-
2010
- 2010-11-16 JP JP2010256249A patent/JP5160622B2/ja not_active Expired - Fee Related
-
2011
- 2011-09-14 JP JP2011200448A patent/JP5250674B2/ja not_active Expired - Fee Related
- 2011-11-24 JP JP2011256171A patent/JP5789178B2/ja not_active Expired - Fee Related
-
2015
- 2015-04-28 JP JP2015091320A patent/JP6154425B2/ja not_active Expired - Fee Related
-
2016
- 2016-09-23 JP JP2016185743A patent/JP6592414B2/ja not_active Expired - Lifetime
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