JP2012067110A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012067110A5 JP2012067110A5 JP2011233850A JP2011233850A JP2012067110A5 JP 2012067110 A5 JP2012067110 A5 JP 2012067110A5 JP 2011233850 A JP2011233850 A JP 2011233850A JP 2011233850 A JP2011233850 A JP 2011233850A JP 2012067110 A5 JP2012067110 A5 JP 2012067110A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- chlorite
- disorder
- tcdo
- matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 claims 10
- 229910001919 chlorite Inorganic materials 0.000 claims 8
- 229910052619 chlorite group Inorganic materials 0.000 claims 8
- VOWOEBADKMXUBU-UHFFFAOYSA-J molecular oxygen;tetrachlorite;hydrate Chemical compound O.O=O.[O-]Cl=O.[O-]Cl=O.[O-]Cl=O.[O-]Cl=O VOWOEBADKMXUBU-UHFFFAOYSA-J 0.000 claims 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 208000035475 disorder Diseases 0.000 claims 6
- 208000024827 Alzheimer disease Diseases 0.000 claims 4
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 4
- 239000013011 aqueous formulation Substances 0.000 claims 4
- -1 chlorite ions Chemical class 0.000 claims 4
- 229940077239 chlorous acid Drugs 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 201000006417 multiple sclerosis Diseases 0.000 claims 4
- 210000002540 macrophage Anatomy 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 208000015122 neurodegenerative disease Diseases 0.000 claims 2
- UKLNMMHNWFDKNT-UHFFFAOYSA-M sodium chlorite Chemical group [Na+].[O-]Cl=O UKLNMMHNWFDKNT-UHFFFAOYSA-M 0.000 claims 2
- 229960002218 sodium chlorite Drugs 0.000 claims 2
- 230000001575 pathological effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54157604P | 2004-02-03 | 2004-02-03 | |
| US60/541,576 | 2004-02-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552151A Division JP5072367B2 (ja) | 2004-02-03 | 2005-01-25 | 神経変性疾患の処置における亜塩素酸 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015118841A Division JP2015205901A (ja) | 2004-02-03 | 2015-06-12 | 神経変性疾患の処置における亜塩素酸 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012067110A JP2012067110A (ja) | 2012-04-05 |
| JP2012067110A5 true JP2012067110A5 (https=) | 2013-04-04 |
| JP5797083B2 JP5797083B2 (ja) | 2015-10-21 |
Family
ID=34860199
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552151A Expired - Lifetime JP5072367B2 (ja) | 2004-02-03 | 2005-01-25 | 神経変性疾患の処置における亜塩素酸 |
| JP2011233850A Expired - Lifetime JP5797083B2 (ja) | 2004-02-03 | 2011-10-25 | 神経変性疾患の処置における亜塩素酸 |
| JP2015118841A Pending JP2015205901A (ja) | 2004-02-03 | 2015-06-12 | 神経変性疾患の処置における亜塩素酸 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552151A Expired - Lifetime JP5072367B2 (ja) | 2004-02-03 | 2005-01-25 | 神経変性疾患の処置における亜塩素酸 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015118841A Pending JP2015205901A (ja) | 2004-02-03 | 2015-06-12 | 神経変性疾患の処置における亜塩素酸 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US7105183B2 (https=) |
| EP (2) | EP1711191B1 (https=) |
| JP (3) | JP5072367B2 (https=) |
| CN (2) | CN101102781B (https=) |
| AU (1) | AU2005213300B2 (https=) |
| CA (2) | CA2554511C (https=) |
| WO (1) | WO2005076819A2 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030126B2 (en) * | 2001-11-16 | 2006-04-18 | Als Therapy Development Foundation, Inc. | Use of polyamine analogs for amyotrophic lateral sclerosis |
| US7105183B2 (en) | 2004-02-03 | 2006-09-12 | The Regents Of The University Of California | Chlorite in the treatment of neurodegenerative disease |
| WO2006009505A1 (en) * | 2004-07-16 | 2006-01-26 | Gyros Patent Ab | Grading of immune responses |
| KR101931899B1 (ko) | 2005-05-09 | 2018-12-21 | 테라노스, 인코포레이티드 | 현장진료 유체 시스템 및 그 용도 |
| DK1915620T3 (da) * | 2005-08-02 | 2010-10-04 | Xbiotech Inc | Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistoffer |
| AU2013234421B2 (en) * | 2005-12-22 | 2015-08-27 | Neuraltus Pharmaceuticals, Inc. | Chlorite formulations, and methods of preparation and use thereof |
| EP1979269A4 (en) | 2005-12-22 | 2013-01-02 | Taiji Biomedical Inc | CHLORINE FORMULATIONS AND PROCESS FOR THE PREPARATION AND USE THEREOF |
| US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
| US8741230B2 (en) | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
| US8007999B2 (en) * | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
| US20110008282A1 (en) * | 2006-05-15 | 2011-01-13 | Xbiotech, Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
| CN102580086A (zh) * | 2006-05-22 | 2012-07-18 | 埃克斯生物科技公司 | 使用抗IL-1α抗体治疗癌症 |
| US20080113391A1 (en) * | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
| FR2910811B1 (fr) * | 2007-01-03 | 2009-07-10 | Ass Pour Le Dev De La Biothera | Utilisation du riluzole et de ses derives pour fabriquer de nouveaux medicaments |
| US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
| CA2726345C (en) * | 2008-05-30 | 2018-08-28 | John Simard | Interleukin-1 alpha antibodies and methods of use |
| AU2009291536B2 (en) * | 2008-09-12 | 2012-08-16 | Xbiotech Inc. | Targeting pathogenic monocytes |
| CN102573500A (zh) * | 2009-08-06 | 2012-07-11 | 纽拉尔图斯制药公司 | 巨噬细胞相关疾病的治疗 |
| CA3081708C (en) | 2009-10-19 | 2023-10-03 | Theranos Ip Company, Llc | Integrated health data capture and analysis system |
| US20130230499A1 (en) * | 2010-03-10 | 2013-09-05 | Michal Eisenbach-Schwartz | Cellular blood markers for early diagnosis of als and for als progression |
| KR102167261B1 (ko) | 2010-06-18 | 2020-10-20 | 엑스바이오테크, 인크. | 관절염 치료 |
| HUE038366T2 (hu) * | 2010-08-16 | 2018-10-29 | Allergan Inc | Módszer szabályozó T-sejtek alfa-2B adrenerg receptor agonistákkal való aktiválásához |
| US10294296B2 (en) | 2010-08-23 | 2019-05-21 | Xbiotech, Inc. | Treatment for neoplastic diseases |
| US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
| ES2695102T3 (es) | 2011-09-23 | 2019-01-02 | Xbiotech Inc | Tratamiento para la caquexia |
| US20130177629A1 (en) | 2011-12-22 | 2013-07-11 | Nuvo Research Gmbh | Liposomal compositions |
| CN107759690A (zh) * | 2012-08-31 | 2018-03-06 | 戊瑞治疗有限公司 | 用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法 |
| US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
| CN106413721A (zh) * | 2014-05-16 | 2017-02-15 | 纽拉尔图斯制药公司 | 用于治疗巨噬细胞相关病症的方法和组合物 |
| EP3072513A1 (en) * | 2015-03-26 | 2016-09-28 | Medday | Biotin for treating Amyotrophic lateral sclerosis |
| EP3370738A2 (en) | 2015-11-02 | 2018-09-12 | Neuraltus Pharmaceuticals, Inc. | Treatment of neurodegenerative disease with sodium chlorite |
| CA3053231A1 (en) | 2017-02-16 | 2018-08-23 | Xbiotech Inc. | Treatment of hidradenitis suppurativa |
| CA3095740A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin alpha (il-1a) |
| CA3095675A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095676A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095679A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleuken 1 alpha (il-1a) |
| JP2024533873A (ja) | 2021-10-04 | 2024-09-12 | ニューヴィヴォ， インコーポレイテッド | Ａｌｓ患者の処置方法 |
| GB2637227A (en) * | 2022-05-19 | 2025-07-16 | Neuvivo Inc | Biomarkers for neurogenerative disease |
| US20250114396A1 (en) * | 2023-07-07 | 2025-04-10 | The Regents Of The University Of California | Chlorite uses for stem cells |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3213389A1 (de) * | 1982-04-10 | 1983-10-20 | Friedrich-Wilhelm Dr. 7107 Neckarsulm Kühne | Stabilisierter aktivierter sauerstoff und arzneimittel, die diesen stabilisierten aktivierten sauerstoff enthalten |
| US4576945A (en) * | 1982-10-26 | 1986-03-18 | Sanders Mark E | Hexaalkylmelamine-amino-oxy compounds |
| DE3515745A1 (de) | 1985-05-02 | 1986-11-06 | Oxo Chemie GmbH, 6900 Heidelberg | Waessrige chloritmatrix-loesung |
| US5051414A (en) * | 1989-08-03 | 1991-09-24 | Dupont Merck Pharmaceutical Company | Inhibition of HIV and other retroviruses by polyoxoanions |
| DE4208828A1 (de) | 1992-03-19 | 1993-09-23 | Oxo Chemie Gmbh | Verwendung einer chemisch stabilisierten chloritmatrix zur herstellung von arzneimitteln zur behandlung von hiv-infektionen |
| US6099855A (en) * | 1992-06-25 | 2000-08-08 | Bioxy, Inc. | Therapeutic, production and immunostimulatory uses of biocidal compositions |
| US5855922A (en) * | 1995-12-07 | 1999-01-05 | Bio-Cide International, Inc. | Antiseptic composition and process for prophylaxis and therapeutic treatment of dermal disorders |
| US5877222A (en) | 1996-07-19 | 1999-03-02 | The Regents Of The University Of California | Method for treating aids-associated dementia |
| DE69821506T2 (de) * | 1997-10-06 | 2004-12-16 | Oxo Chemie Ag | Verwendung einer chemisch stabilisierten chloritlösung zur inhibition der antigenspezifischen immunantwort |
| US7087648B1 (en) | 1997-10-27 | 2006-08-08 | The Regents Of The University Of California | Methods for modulating macrophage proliferation using polyamine analogs |
| JP2001078775A (ja) * | 1999-09-14 | 2001-03-27 | Kokuritsu Seishin Shinkei Center | マクロファージ機能調節剤 |
| JP2003515349A (ja) * | 1999-11-30 | 2003-05-07 | オクソ ヒェミー アーゲー | 遺伝子発現の解析による臨床結果の評価および予測 |
| US6685754B2 (en) | 2001-03-06 | 2004-02-03 | Alchemix Corporation | Method for the production of hydrogen-containing gaseous mixtures |
| US7030126B2 (en) | 2001-11-16 | 2006-04-18 | Als Therapy Development Foundation, Inc. | Use of polyamine analogs for amyotrophic lateral sclerosis |
| US7105183B2 (en) * | 2004-02-03 | 2006-09-12 | The Regents Of The University Of California | Chlorite in the treatment of neurodegenerative disease |
-
2005
- 2005-01-24 US US11/042,816 patent/US7105183B2/en not_active Expired - Lifetime
- 2005-01-25 JP JP2006552151A patent/JP5072367B2/ja not_active Expired - Lifetime
- 2005-01-25 CN CN2005800037236A patent/CN101102781B/zh not_active Expired - Lifetime
- 2005-01-25 WO PCT/US2005/002469 patent/WO2005076819A2/en not_active Ceased
- 2005-01-25 AU AU2005213300A patent/AU2005213300B2/en not_active Expired
- 2005-01-25 EP EP05722556.7A patent/EP1711191B1/en not_active Expired - Lifetime
- 2005-01-25 CA CA2554511A patent/CA2554511C/en not_active Expired - Lifetime
- 2005-01-25 EP EP12192303.1A patent/EP2574342B1/en not_active Expired - Lifetime
- 2005-01-25 CN CN201110317862.3A patent/CN102423318B/zh not_active Expired - Lifetime
- 2005-01-25 CA CA2838392A patent/CA2838392C/en not_active Expired - Lifetime
-
2006
- 2006-03-17 US US11/378,987 patent/US8029826B2/en active Active
-
2010
- 2010-10-07 US US12/900,361 patent/US20110053186A1/en not_active Abandoned
-
2011
- 2011-10-25 JP JP2011233850A patent/JP5797083B2/ja not_active Expired - Lifetime
-
2012
- 2012-04-27 US US13/458,954 patent/US9364501B2/en not_active Expired - Lifetime
-
2015
- 2015-06-12 JP JP2015118841A patent/JP2015205901A/ja active Pending
-
2016
- 2016-09-12 US US15/262,981 patent/US20170065634A1/en not_active Abandoned