JP2011530701A5 - - Google Patents
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- Publication number
- JP2011530701A5 JP2011530701A5 JP2011522287A JP2011522287A JP2011530701A5 JP 2011530701 A5 JP2011530701 A5 JP 2011530701A5 JP 2011522287 A JP2011522287 A JP 2011522287A JP 2011522287 A JP2011522287 A JP 2011522287A JP 2011530701 A5 JP2011530701 A5 JP 2011530701A5
- Authority
- JP
- Japan
- Prior art keywords
- angiotensin
- sample
- amount
- ions
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101800000734 Angiotensin-1 Proteins 0.000 claims 36
- 102400000344 Angiotensin-1 Human genes 0.000 claims 36
- 238000000034 method Methods 0.000 claims 34
- 150000002500 ions Chemical class 0.000 claims 31
- 108090000783 Renin Proteins 0.000 claims 11
- 102100028255 Renin Human genes 0.000 claims 11
- 238000004949 mass spectrometry Methods 0.000 claims 8
- 230000000694 effects Effects 0.000 claims 6
- 238000004811 liquid chromatography Methods 0.000 claims 5
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims 4
- 230000015556 catabolic process Effects 0.000 claims 4
- 238000006731 degradation reaction Methods 0.000 claims 4
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 4
- 238000004128 high performance liquid chromatography Methods 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000002414 normal-phase solid-phase extraction Methods 0.000 claims 3
- PGPBBDLLMZHPIX-UHFFFAOYSA-N 3-amino-1-phenylpropane-1-sulfonyl fluoride Chemical group NCCC(S(F)(=O)=O)C1=CC=CC=C1 PGPBBDLLMZHPIX-UHFFFAOYSA-N 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000002243 precursor Substances 0.000 claims 2
- 238000011002 quantification Methods 0.000 claims 2
- 108010064733 Angiotensins Proteins 0.000 claims 1
- 102000015427 Angiotensins Human genes 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 238000011534 incubation Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/189,092 | 2008-08-08 | ||
| US12/189,092 US7834313B2 (en) | 2008-08-08 | 2008-08-08 | Mass spectrometry assay for plasma-renin |
| PCT/US2009/053189 WO2010017499A1 (en) | 2008-08-08 | 2009-08-07 | Mass spectrometry assay for plasma-renin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013194007A Division JP5855062B2 (ja) | 2008-08-08 | 2013-09-19 | 血漿レニンの質量分析法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011530701A JP2011530701A (ja) | 2011-12-22 |
| JP2011530701A5 true JP2011530701A5 (cg-RX-API-DMAC7.html) | 2012-09-27 |
| JP5373902B2 JP5373902B2 (ja) | 2013-12-18 |
Family
ID=41652003
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011522287A Active JP5373902B2 (ja) | 2008-08-08 | 2009-08-07 | 血漿レニンの質量分析法 |
| JP2013194007A Active JP5855062B2 (ja) | 2008-08-08 | 2013-09-19 | 血漿レニンの質量分析法 |
| JP2015239495A Active JP6110469B2 (ja) | 2008-08-08 | 2015-12-08 | 血漿レニンの質量分析法 |
| JP2017044480A Active JP6396525B2 (ja) | 2008-08-08 | 2017-03-09 | 血漿レニンの質量分析法 |
| JP2018159953A Active JP7154887B2 (ja) | 2008-08-08 | 2018-08-29 | 血漿レニンの質量分析法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013194007A Active JP5855062B2 (ja) | 2008-08-08 | 2013-09-19 | 血漿レニンの質量分析法 |
| JP2015239495A Active JP6110469B2 (ja) | 2008-08-08 | 2015-12-08 | 血漿レニンの質量分析法 |
| JP2017044480A Active JP6396525B2 (ja) | 2008-08-08 | 2017-03-09 | 血漿レニンの質量分析法 |
| JP2018159953A Active JP7154887B2 (ja) | 2008-08-08 | 2018-08-29 | 血漿レニンの質量分析法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7834313B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2310824B1 (cg-RX-API-DMAC7.html) |
| JP (5) | JP5373902B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN102112857B (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0917497B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2732109C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010017499A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2721049B2 (ja) | 1991-05-13 | 1998-03-04 | 株式会社クボタ | 包装装置 |
| JP2771344B2 (ja) | 1991-05-14 | 1998-07-02 | 株式会社クボタ | 包装装置 |
| SG183001A1 (en) * | 2007-08-24 | 2012-08-30 | Emd Millipore Corp | System and method for diversion of a liquid chromatography eluant |
| US7834313B2 (en) * | 2008-08-08 | 2010-11-16 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
| US8106351B2 (en) * | 2008-08-08 | 2012-01-31 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
| EP3486648B1 (en) * | 2008-12-24 | 2025-04-30 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for congenital adrenal hyperplasia |
| JP5675442B2 (ja) * | 2011-03-04 | 2015-02-25 | 株式会社日立ハイテクノロジーズ | 質量分析方法及び質量分析装置 |
| CN103858143B (zh) * | 2011-10-13 | 2017-08-25 | 皇家飞利浦有限公司 | 评级请求从推荐系统的自动生成 |
| EP2859343B1 (en) * | 2012-06-06 | 2019-10-23 | Attoquant Diagnostics GmbH | Method for measurement of peptidic degradation products of a proteolytic cascade in blood samples |
| CA2948823C (en) | 2014-05-12 | 2020-09-22 | Quest Diagnostics Investments Incorporated | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| JP6198693B2 (ja) * | 2014-08-06 | 2017-09-20 | 三菱電機株式会社 | リモコン装置 |
| EP3542166B9 (en) | 2016-11-17 | 2023-10-04 | Laboratory Corporation of America Holdings | Methods and systems for determining plasma angiotensin i levels. |
| JP7067758B2 (ja) * | 2017-06-30 | 2022-05-16 | 国立大学法人 新潟大学 | 試料中のアンジオテンシンペプチドの量を測定するための方法及びアンジオテンシンペプチドの定量キット |
| CN110243917A (zh) * | 2018-03-09 | 2019-09-17 | 中国科学院天津工业生物技术研究所 | 一种快速检测小分子化合物的方法 |
| US11674969B2 (en) * | 2018-03-16 | 2023-06-13 | Quest Diagnostics Investments Llc | Mass spectrometric determination of testosterone in multiplexed patient samples |
| CN112014509A (zh) * | 2020-09-03 | 2020-12-01 | 复旦大学附属中山医院 | 同步测定样品中血管紧张素i和醛固酮的方法 |
| CN117647606B (zh) * | 2024-01-30 | 2024-09-03 | 西湖欧米(杭州)生物科技有限公司 | 适于lc-ms/ms能同时检测多种蛋白的试剂盒 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3919407A (en) * | 1973-11-28 | 1975-11-11 | De Castro Aurora L Fernandez | Method for quantitative determination of renin activity in blood |
| US3984532A (en) * | 1973-11-28 | 1976-10-05 | Fernandez De Castro Aurora L | Method for quantitative determination of renin activity in blood employing phenyl methyl sulfonyl fluoride and polyethylene glycol |
| US4022577A (en) * | 1976-03-12 | 1977-05-10 | The University Of Virginia | Automated radioimmunoassay |
| US4112064A (en) * | 1977-02-22 | 1978-09-05 | Hoffmann-La Roche Inc. | Stabilized angiotensin I solutions |
| JPS63217272A (ja) * | 1987-03-06 | 1988-09-09 | Daiichi Rajio Isotope Kenkyusho:Kk | 活性型レニン測定法 |
| GB2267385B (en) * | 1992-05-29 | 1995-12-13 | Finnigan Corp | Method of detecting the ions in an ion trap mass spectrometer |
| US5605798A (en) * | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| ATE242485T1 (de) * | 1993-05-28 | 2003-06-15 | Baylor College Medicine | Verfahren und massenspektrometer zur desorption und ionisierung von analyten |
| US5572025A (en) * | 1995-05-25 | 1996-11-05 | The Johns Hopkins University, School Of Medicine | Method and apparatus for scanning an ion trap mass spectrometer in the resonance ejection mode |
| JPH09119916A (ja) * | 1995-10-24 | 1997-05-06 | Sumika Bunseki Center:Kk | 微量化合物の定量分析方法 |
| US5772874A (en) | 1995-11-02 | 1998-06-30 | Cohesive Technologies, Inc. | High performance liquid chromatography method and apparatus |
| AU712735B2 (en) | 1996-01-19 | 1999-11-11 | Cohesive Technologies, Inc. | High performance liquid chromatography method and apparatus |
| GB9717926D0 (en) * | 1997-08-22 | 1997-10-29 | Micromass Ltd | Methods and apparatus for tandem mass spectrometry |
| US5869832A (en) * | 1997-10-14 | 1999-02-09 | University Of Washington | Device and method for forming ions |
| US6107626A (en) * | 1997-10-14 | 2000-08-22 | The University Of Washington | Device and method for forming ions |
| US6040575A (en) * | 1998-01-23 | 2000-03-21 | Analytica Of Branford, Inc. | Mass spectrometry from surfaces |
| JP2002524723A (ja) * | 1998-09-04 | 2002-08-06 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション | パラクリンの尿細管レニン−アンジオテンシン系に基づく薬物スクリーニングおよび診断 |
| US7300753B2 (en) | 1998-09-04 | 2007-11-27 | John Rush | Immunoaffinity isolation of modified peptides from complex mixtures |
| AU2001236726A1 (en) * | 2000-02-08 | 2001-08-20 | The Regents Of The University Of Michigan | Protein separation and display |
| CA2438247A1 (en) * | 2001-02-20 | 2002-08-29 | Xian Huang | A microchip electrospray device and column with affinity adsorbents and use of the same |
| JP3865129B2 (ja) * | 2002-08-19 | 2007-01-10 | 株式会社島津製作所 | Ｌｃ−ｍｓ分析方法及びその移動相 |
| US6977143B1 (en) * | 2003-09-08 | 2005-12-20 | Quest Diagnostics Investments Incorporated | Determination of testosterone by mass spectrometry |
| JP4512589B2 (ja) * | 2004-02-26 | 2010-07-28 | 独立行政法人科学技術振興機構 | 表面加工が施された試料保持面を有する試料ターゲットおよびその製造方法、並びに当該試料ターゲットを用いた質量分析装置 |
| KR20070030264A (ko) * | 2004-06-07 | 2007-03-15 | 나스텍 파마수티컬 컴퍼니 인코포레이티드 | 단백질 또는 폴리펩티드 안정제 성분을 함유하지 않은인터페론 베타의 비강내 투여를 위한 제형들 |
| EP1619503A1 (en) | 2004-07-15 | 2006-01-25 | BioVisioN AG | Use of standards for monitoring alterations of peptide and protein samples |
| US7332296B2 (en) * | 2004-12-02 | 2008-02-19 | Wright State University | Screening assay for enzymes involved in pathophysiology using SELDI-TOF mass spectrometry |
| JP2006180813A (ja) * | 2004-12-28 | 2006-07-13 | Daiichi Fine Chemical Co Ltd | アミノペプチダーゼｏおよびその利用 |
| JP5030240B2 (ja) * | 2006-06-06 | 2012-09-19 | エフ．ホフマン−ラ ロシュ アーゲー | すぐ使用できる全血回収容器 |
| JP2008007482A (ja) * | 2006-06-30 | 2008-01-17 | Univ Of Miyazaki | 昇圧作用を有する新規ポリペプチド |
| JP5276993B2 (ja) * | 2007-01-31 | 2013-08-28 | 中外製薬株式会社 | 低分子量ペプチドの高感度定量方法 |
| WO2009036336A2 (en) * | 2007-09-12 | 2009-03-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomarkers for motor neuron disease |
| US7834313B2 (en) | 2008-08-08 | 2010-11-16 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
-
2008
- 2008-08-08 US US12/189,092 patent/US7834313B2/en active Active
-
2009
- 2009-08-07 JP JP2011522287A patent/JP5373902B2/ja active Active
- 2009-08-07 BR BRPI0917497A patent/BRPI0917497B8/pt active IP Right Grant
- 2009-08-07 CN CN2009801302082A patent/CN102112857B/zh active Active
- 2009-08-07 WO PCT/US2009/053189 patent/WO2010017499A1/en not_active Ceased
- 2009-08-07 CN CN201310436176.7A patent/CN103743848B/zh active Active
- 2009-08-07 CA CA2732109A patent/CA2732109C/en active Active
- 2009-08-07 EP EP09805622.9A patent/EP2310824B1/en active Active
- 2009-08-07 EP EP12194783.2A patent/EP2565905B1/en active Active
-
2013
- 2013-09-19 JP JP2013194007A patent/JP5855062B2/ja active Active
-
2015
- 2015-12-08 JP JP2015239495A patent/JP6110469B2/ja active Active
-
2017
- 2017-03-09 JP JP2017044480A patent/JP6396525B2/ja active Active
-
2018
- 2018-08-29 JP JP2018159953A patent/JP7154887B2/ja active Active
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