JP2011530385A - 閉塞性睡眠時無呼吸症を治療するための方法及び装置 - Google Patents
閉塞性睡眠時無呼吸症を治療するための方法及び装置 Download PDFInfo
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Abstract
Description
(1) 咽頭壁の下側の組織に植え込むことによって前記咽頭壁の形状を変化させるための装置であって、
拘束形態及び前記拘束形態とは異なる非拘束形態を有する収縮要素と、
前記収縮要素に連結され、前記咽頭壁の下側の前記組織と係合するように構成された組織係合要素と、を備え、
前記収縮要素が前記拘束形態から前記非拘束形態に復帰する際に前記咽頭壁の形状が変化させられる、装置。
(2) 前記収縮要素及び前記組織係合要素の少なくとも一方に取り付けられ、前記収縮要素及び前記組織係合要素を前記咽頭壁の下側の前記組織内に配置するための形状を有するトロカールを更に備える、実施態様1に記載の装置。
(3) 前記トロカールの遠位端部を包囲するプラスチックスリーブを更に備え、前記装置が前記プラスチックスリーブの近位端部に取り付けられる、実施態様2に記載の装置。
(4) 前記装置が植え込まれる際に非標的組織を保護するために前記組織係合要素の少なくとも一部を覆うシースを更に備える、実施態様1に記載の装置。
(5) 前記組織係合要素が、医療用織物及び穿孔されたシートからなる群から選択される材料を含む、実施態様1に記載の装置。
(6) 前記組織係合要素が、逆棘、突起、ベロア、及びフック要素からなる群から選択される組織係合特徴部を含む、実施態様1に記載の装置。
(7) 前記収縮要素が、ニチノール、ステンレス鋼、タンタル、及びチタンからなる群から選択される金属から構成される、実施態様1に記載の装置。
(8) 前記収縮要素が可撓性アーチを含む、実施態様1に記載の装置。
(9) 前記収縮要素及び前記組織係合要素が、接着剤、縫合糸、クリップ、リベット、織り込み、及び封入からなる群から選択される取付け手段を使用して取り付けられる、実施態様1に記載の装置。
(10) 前記装置に塗布される画像強調物質であって、放射性不透過性物質及び音波発生物質からなる群から選択される、物質を更に含む、実施態様1に記載の装置。
(12) 閉塞性睡眠時無呼吸症を外科的に治療するための方法であって、
咽頭壁の下側に位置する組織内にインプラント装置を導入する工程と、
前記咽頭壁の下側の前記組織と前記インプラント装置を係合させることによって前記咽頭壁の形状を変化させる工程と、を含む、方法。
(13) 前記咽頭壁に1又は2以上の切開口を形成する工程を更に含む、実施態様12に記載の方法。
(14) 前記咽頭壁の一部の曲率半径を変化させる工程を更に含む、実施態様12に記載の方法。
(15) 前記インプラント装置内への組織の内部成長を誘導する工程を更に含む、実施態様12に記載の方法。
(16) 前記導入する工程が、前記インプラント装置を口から前記咽頭壁を通じて前記咽頭壁の下側の前記組織内に差し込む工程を更に含む、実施態様12に記載の方法。
(17) 前記導入する工程が、
前記咽頭壁にトロカールを貫通させる工程と、
前記トロカールを操作して前記装置を前記咽頭壁の下側の前記組織内に導入する工程と、を更に含む、実施態様12に記載の方法。
(18) 前記導入する工程が、
拘束状態の少なくとも1つのインプラント装置を収納した手持ち式導入システムの遠位端部を前記咽頭壁に隣接して配置する工程と、
前記手持ち式導入システムのレバーを作動させて前記インプラント装置を前記咽頭壁の下側の前記組織内に展開する工程であって、前記インプラント装置が、前記拘束状態とは異なる形状を有する非拘束状態をとる、工程と、を更に含む、実施態様12に記載の方法。
(19) 前記インプラント装置が前記装置の少なくとも一部を包囲する保護シースを含み、前記方法が、
前記シースを取り外すことによって前記インプラント装置を前記咽頭壁の下側の前記組織と係合させる工程を更に含む、実施態様12に記載の方法。
(20) 咽頭壁の形状を変化させることによって閉塞性睡眠時無呼吸症を治療するためのシステムであって、
組織係合要素と収縮要素とを含むインプラント装置と、
ハンドピースと、前記ハンドピースに動作可能に連結された作動レバーと、前記ハンドピースから遠位方向に延びるシャフトと、少なくとも1つのインプラント装置を格納するために前記シャフトの遠位端部に配置されたハウジングと、前記咽頭壁の形状を変化させるために、前記咽頭壁の下側に位置する組織空間内に前記咽頭壁を通じて前記インプラント装置を展開するように前記レバーによって作動可能な展開装置と、を含む手持ち式導入システムと、を備える、システム。
前記シャフトの前記遠位端部に配置された前記ハウジングが、前記拘束状態の前記少なくとも1つのインプラント装置を格納するためのものである、実施態様20に記載のシステム。
(22) 前記インプラント装置が2個の端部を有するアーチ形部材を含み、前記端部間の距離が、前記インプラント装置が前記拘束状態から前記非拘束状態に変化する際に変化する、実施態様21に記載のシステム。
(23) 前記手持ち式導入システムの前記遠位端部が、
内部を通じて前記インプラント装置を展開する切開口を前記咽頭壁に形成するための鋭いエッジを更に含む、実施態様20に記載のシステム。
(24) 咽頭壁を収縮させるための装置であって、
前記咽頭壁の下側の組織と係合するための中央部分と、前記中央部分から延びる第1及び第2の収縮部分とを有する細長い繊維状部材を含み、前記第1及び第2の収縮部分のそれぞれが、頸部の組織と係合して前記中央部分に引張収縮力を作用させる特徴部を有する、装置。
(25) 前記細長い繊維状部材が単一フィラメントを含み、前記頸部の組織と係合して前記中央部分に引張収縮力を作用させる前記特徴部が逆棘を含む、実施態様24に記載の装置。
(26) 前記収縮部分の少なくとも一方の遠位端部に取り付けられて前記頸部の前記組織にその収縮部分を通過させる針を更に含む、実施態様24に記載の装置。
Claims (18)
- 咽頭壁の下側の組織に植え込むことによって前記咽頭壁の形状を変化させるための装置であって、
拘束形態及び前記拘束形態とは異なる非拘束形態を有する収縮要素と、
前記収縮要素に連結され、前記咽頭壁の下側の前記組織と係合するように構成された組織係合要素と、を備え、
前記収縮要素が前記拘束形態から前記非拘束形態に復帰する際に前記咽頭壁の形状が変化させられる、装置。 - 前記収縮要素及び前記組織係合要素の少なくとも一方に取り付けられ、前記収縮要素及び前記組織係合要素を前記咽頭壁の下側の前記組織内に配置するための形状を有するトロカールを更に備える、請求項1に記載の装置。
- 前記トロカールの遠位端部を包囲するプラスチックスリーブを更に備え、前記装置が前記プラスチックスリーブの近位端部に取り付けられる、請求項2に記載の装置。
- 前記装置が植え込まれる際に非標的組織を保護するために前記組織係合要素の少なくとも一部を覆うシースを更に備える、請求項1に記載の装置。
- 前記組織係合要素が、医療用織物及び穿孔されたシートからなる群から選択される材料を含む、請求項1に記載の装置。
- 前記組織係合要素が、逆棘、突起、ベロア、及びフック要素からなる群から選択される組織係合特徴部を含む、請求項1に記載の装置。
- 前記収縮要素が、ニチノール、ステンレス鋼、タンタル、及びチタンからなる群から選択される金属から構成される、請求項1に記載の装置。
- 前記収縮要素が可撓性アーチを含む、請求項1に記載の装置。
- 前記収縮要素及び前記組織係合要素が、接着剤、縫合糸、クリップ、リベット、織り込み、及び封入からなる群から選択される取付け手段を使用して取り付けられる、請求項1に記載の装置。
- 前記装置に塗布される画像強調物質であって、放射性不透過性物質及び音波発生物質からなる群から選択される、物質を更に含む、請求項1に記載の装置。
- 前記装置に塗布される薬剤であって、抗微生物剤、鎮痛剤、抗生物質、抗炎症剤、痛み止め薬からなる群から選択される、薬剤を更に含む、請求項1に記載の装置。
- 咽頭壁の形状を変化させることによって閉塞性睡眠時無呼吸症を治療するためのシステムであって、
組織係合要素と収縮要素とを含むインプラント装置と、
ハンドピースと、前記ハンドピースに動作可能に連結された作動レバーと、前記ハンドピースから遠位方向に延びるシャフトと、少なくとも1つのインプラント装置を格納するために前記シャフトの遠位端部に配置されたハウジングと、前記咽頭壁の形状を変化させるために、前記咽頭壁の下側に位置する組織空間内に前記咽頭壁を通じて前記インプラント装置を展開するように前記レバーによって作動可能な展開装置と、を含む手持ち式導入システムと、を備える、システム。 - 前記インプラント装置が拘束状態と、前記拘束状態とは異なる形状を有する非拘束状態とを有し、
前記シャフトの前記遠位端部に配置された前記ハウジングが、前記拘束状態の前記少なくとも1つのインプラント装置を格納するためのものである、請求項12に記載のシステム。 - 前記インプラント装置が2個の端部を有するアーチ形部材を含み、前記端部間の距離が、前記インプラント装置が前記拘束状態から前記非拘束状態に変化する際に変化する、請求項13に記載のシステム。
- 前記手持ち式導入システムの前記遠位端部が、
内部を通じて前記インプラント装置を展開する切開口を前記咽頭壁に形成するための鋭いエッジを更に含む、請求項12に記載のシステム。 - 咽頭壁を収縮させるための装置であって、
前記咽頭壁の下側の組織と係合するための中央部分と、前記中央部分から延びる第1及び第2の収縮部分とを有する細長い繊維状部材を含み、前記第1及び第2の収縮部分のそれぞれが、頸部の組織と係合して前記中央部分に引張収縮力を作用させる特徴部を有する、装置。 - 前記細長い繊維状部材が単一フィラメントを含み、前記頸部の組織と係合して前記中央部分に引張収縮力を作用させる前記特徴部が逆棘を含む、請求項16に記載の装置。
- 前記収縮部分の少なくとも一方の遠位端部に取り付けられて前記頸部の前記組織にその収縮部分を通過させる針を更に含む、請求項16に記載の装置。
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US12/228,681 US8413661B2 (en) | 2008-08-14 | 2008-08-14 | Methods and devices for treatment of obstructive sleep apnea |
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PCT/US2009/051921 WO2010019376A2 (en) | 2008-08-14 | 2009-07-28 | Methods and devices for treatment of obstructive sleep apnea |
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US9144511B2 (en) | 2015-09-29 |
EP2341876B1 (en) | 2015-08-19 |
EP2341876A2 (en) | 2011-07-13 |
JP2014140752A (ja) | 2014-08-07 |
JP5474970B2 (ja) | 2014-04-16 |
US20130174857A1 (en) | 2013-07-11 |
WO2010019376A2 (en) | 2010-02-18 |
US20100037901A1 (en) | 2010-02-18 |
WO2010019376A3 (en) | 2010-04-15 |
ES2552224T3 (es) | 2015-11-26 |
US8413661B2 (en) | 2013-04-09 |
JP5872601B2 (ja) | 2016-03-01 |
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