JP2011527984A - 虚血性又は炎症性の心疾患及び心臓血管疾患の予防と治療のためのフラボノイド化合物の使用 - Google Patents

虚血性又は炎症性の心疾患及び心臓血管疾患の予防と治療のためのフラボノイド化合物の使用 Download PDF

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JP2011527984A
JP2011527984A JP2010549125A JP2010549125A JP2011527984A JP 2011527984 A JP2011527984 A JP 2011527984A JP 2010549125 A JP2010549125 A JP 2010549125A JP 2010549125 A JP2010549125 A JP 2010549125A JP 2011527984 A JP2011527984 A JP 2011527984A
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glucuronide
quercetin
kaempferol
glucoside
heart
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JP2011527984A5 (https=
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アンケ エシュペレシュター
シュテファン ネーズ
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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Publication of JP2011527984A publication Critical patent/JP2011527984A/ja
Publication of JP2011527984A5 publication Critical patent/JP2011527984A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2010549125A 2008-03-06 2009-03-03 虚血性又は炎症性の心疾患及び心臓血管疾患の予防と治療のためのフラボノイド化合物の使用 Pending JP2011527984A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008012909.7 2008-03-06
DE102008012909A DE102008012909A1 (de) 2008-03-06 2008-03-06 Verwendung von Flavonoidverbindungen für die Prophylaxe und Therapie ischämischer oder entzündlicher Herz- und Kreislauferkrankungen
PCT/EP2009/052502 WO2009109573A1 (de) 2008-03-06 2009-03-03 Verwendung von flavonoidverbindungen für die propyhylaxe und therapie ischämischer oder entzündlicher herz- und kreislauferkrankungen

Publications (2)

Publication Number Publication Date
JP2011527984A true JP2011527984A (ja) 2011-11-10
JP2011527984A5 JP2011527984A5 (https=) 2012-04-26

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ID=40600026

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JP2010549125A Pending JP2011527984A (ja) 2008-03-06 2009-03-03 虚血性又は炎症性の心疾患及び心臓血管疾患の予防と治療のためのフラボノイド化合物の使用

Country Status (6)

Country Link
US (2) US20110053874A1 (https=)
EP (1) EP2268277A1 (https=)
JP (1) JP2011527984A (https=)
CA (1) CA2717012A1 (https=)
DE (1) DE102008012909A1 (https=)
WO (1) WO2009109573A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009027382A2 (de) * 2007-08-31 2009-03-05 Boehringer Ingelheim International Gmbh Sprühfähige zusammensetzung enthaltend extrakt aus rotem weinlaub
DE102008012908A1 (de) * 2008-03-06 2009-09-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Methode zum anti-inflammatorischen und anti-ödematösen Schutz von explantiertem biologischen Material bis zu seiner Transplantation in Patienten
BR112015008156A2 (pt) 2012-10-11 2017-07-04 Armaron Bio Pty Ltd novos compostos flavonóides e suas respectivas utilizações
CN113398114B (zh) * 2021-05-28 2022-11-01 浙江大学智能创新药物研究院 3,7,8,4′-四羟基黄酮在制备抗心血管疾病药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003534285A (ja) * 2000-05-25 2003-11-18 ファルマトン ソシエテ アノニム 細胞保護を改善する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69918852T2 (de) * 1998-10-29 2005-07-21 Merck Patent Gmbh Zusammensetzung enthaltend eine mischung von bioflavonoiden
JP2001122791A (ja) 1999-10-20 2001-05-08 Boehringer Ingelheim Internatl Gmbh 下肢の慢性静脈不全の軽減および予防のための赤色ブドウ樹葉の水性抽出物よりなる食事補強剤
CN1197567C (zh) * 2002-10-21 2005-04-20 中国人民解放军第二军医大学 山奈酚衍生物用于制备防治脑血管疾病药物的用途
AU2003298180B2 (en) 2002-12-31 2010-01-21 Boehringer Ingelheim International Gmbh Film coated tablet comprising an extract of red vine leaves

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003534285A (ja) * 2000-05-25 2003-11-18 ファルマトン ソシエテ アノニム 細胞保護を改善する方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN5012007453; ＥＳＰＥＲＥＳＴＥＲ　ＡＮＫＥ: 'ＱＵＥＲＣＥＴＩＮ-ＧＬＵＣＵＲＯＮＩＤＥ　（ＱＧ）　ＰＲＥＶＥＮＴＳ　ＭＩＣＲＯＣＩＲＣＵＬＡＴＯＲＹ　ＣＯＭＰＬＩＣＡＴＩＯＮＳ　ＡＣＵＴＥＬＹ　ＣＡＵＳＥＤ　以下備考' ＣＩＲＣＵＬＡＴＩＯＮ Ｖ１１０　Ｎ１７　ＳＵＰＰＬ．Ｓ, 200410, Ｐ１２６ *
JPN5012007454; ＦＡＮＴＩＮＥＬＬＩ　ＪＵＬＩＡＮＡ　Ｃ: 'ＣＡＲＤＩＯＰＲＯＴＥＣＴＩＶＥ　ＥＦＦＥＣＴＳ　ＯＦ　Ａ　ＮＯＮ-ＡＬＣＯＨＯＬＩＣ　ＥＸＴＲＡＣＴ　ＯＦ　ＲＥＤ　ＷＩＮＥ　ＤＵＲＩＮＧ　ＩＳＣＨＡＥＭＩＡ　以下備考' ＣＬＩＮＩＣＡＬ　ＡＮＤ　ＥＸＰＥＲＩＭＥＮＴＡＬ　ＰＨＡＲＭＡＣＯＬＯＧＹ　ＡＮＤ　ＰＨＹＳＩＯＬＯＧＹ Ｖ３４　Ｎ３, 200703, Ｐ１６６-１６９ *
JPN5012007456; ＫＩＥＳＥＷＥＴＴＥＲ　Ｈ: 'ＥＦＦＩＣＡＣＹ　ＯＦ　ＯＲＡＬＬＹ　ＡＤＭＩＮＩＳＴＥＲＥＤ　ＥＸＴＲＡＣＴ　ＯＦ　ＲＥＤ　ＶＩＮＥ　ＬＥＡＦ　ＡＳ　１９５　（ＦＯＬＩＡ　ＶＩＴＩＳ　ＶＩＮＩＦＥＲＡＥ）　以下備考' ＡＲＺＮＥＩＭＩＴＴＥＬ　ＦＯＲＳＣＨＵＮＧ／ＤＲＵＧ　ＲＥＳＥＡＲＣＨ Ｖ５０　Ｎ２, 20000101, Ｐ１０９-１１７, ＥＣＶ　ＥＤＩＴＩＯ　ＣＡＮＴＯＲ　ＶＥＲＬＡＧ *
JPN6010027017; ＬＡＲＤＯＳ　Ａ　ｅｔ　ａｌ: '薬用ハ-ブの機能性とその利用について　ＩＩＩ　赤ブドウの葉（Ｒｅｄ　Ｖｉｎｅ　Ｌｅａｆ）' 食品と開発 ２００１，Ｖｏｌ．３６，Ｎｏ．３, Ｐａｇｅ．５０-５３ *

Also Published As

Publication number Publication date
US20110053874A1 (en) 2011-03-03
US20130109641A1 (en) 2013-05-02
CA2717012A1 (en) 2009-09-11
DE102008012909A1 (de) 2009-09-10
WO2009109573A1 (de) 2009-09-11
EP2268277A1 (de) 2011-01-05

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