JP2011527709A5 - - Google Patents
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- Publication number
- JP2011527709A5 JP2011527709A5 JP2011517670A JP2011517670A JP2011527709A5 JP 2011527709 A5 JP2011527709 A5 JP 2011527709A5 JP 2011517670 A JP2011517670 A JP 2011517670A JP 2011517670 A JP2011517670 A JP 2011517670A JP 2011527709 A5 JP2011527709 A5 JP 2011527709A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- azithromycin
- subject
- effective amount
- blepharitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 26
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 claims 14
- 229960004099 azithromycin Drugs 0.000 claims 14
- 208000010217 blepharitis Diseases 0.000 claims 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 6
- 230000001684 chronic effect Effects 0.000 claims 6
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 4
- 206010013774 Dry eye Diseases 0.000 claims 4
- 230000002757 inflammatory effect Effects 0.000 claims 4
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims 3
- 229920000148 Polycarbophil calcium Polymers 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 230000002458 infectious effect Effects 0.000 claims 3
- 229950005134 polycarbophil Drugs 0.000 claims 3
- 239000011780 sodium chloride Substances 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 206010010804 Contact lens intolerance Diseases 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7977208P | 2008-07-10 | 2008-07-10 | |
| US61/079,772 | 2008-07-10 | ||
| PCT/US2009/050311 WO2010006306A1 (en) | 2008-07-10 | 2009-07-10 | Method of treating blepharitis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014190105A Division JP2014240433A (ja) | 2008-07-10 | 2014-09-18 | 眼瞼炎の治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011527709A JP2011527709A (ja) | 2011-11-04 |
| JP2011527709A5 true JP2011527709A5 (enExample) | 2012-07-12 |
Family
ID=41507457
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011517670A Withdrawn JP2011527709A (ja) | 2008-07-10 | 2009-07-10 | 眼瞼炎の治療方法 |
| JP2014190105A Ceased JP2014240433A (ja) | 2008-07-10 | 2014-09-18 | 眼瞼炎の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014190105A Ceased JP2014240433A (ja) | 2008-07-10 | 2014-09-18 | 眼瞼炎の治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8349806B2 (enExample) |
| EP (1) | EP2313103B1 (enExample) |
| JP (2) | JP2011527709A (enExample) |
| AU (1) | AU2009268372B2 (enExample) |
| CA (1) | CA2730120A1 (enExample) |
| MX (1) | MX2011000247A (enExample) |
| WO (1) | WO2010006306A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9925087B2 (en) | 2000-09-15 | 2018-03-27 | Bruder Healthcare Company, Llc | Wound and therapy compress and dressing |
| US10105259B2 (en) | 2000-09-15 | 2018-10-23 | Bruder Healthcare Company, Llc | Wound and therapy compress and dressing |
| ATE460146T1 (de) | 2000-09-15 | 2010-03-15 | Bruder Healthcare Co | Wund- und behandlungskompresse und verband |
| US8349806B2 (en) | 2008-07-10 | 2013-01-08 | Inspire Pharmaceuticals, Inc. | Method of treating blepharitis |
| US20100190734A1 (en) * | 2009-01-23 | 2010-07-29 | Romulus Kimbro Brazzell | Method of treating dry eye disease with azithromycin |
| US20130281390A1 (en) * | 2010-12-29 | 2013-10-24 | Kurt E. Brubaker | Method for treating dry eye |
| WO2012092378A1 (en) * | 2010-12-29 | 2012-07-05 | Inspire Pharmaceuticals, Inc. | Method for treating blepharitis |
| JP2014518275A (ja) * | 2011-06-29 | 2014-07-28 | インサイト・ビジョン・インコーポレイテッド | 再発性マイボーム腺障害の処置方法およびそれによる再発頻度の減少方法 |
| WO2013191167A1 (ja) * | 2012-06-19 | 2013-12-27 | 参天製薬株式会社 | ヘアレス動物の眼瞼状態の変化方法 |
| WO2014143139A1 (en) | 2013-03-15 | 2014-09-18 | Bruder Healthcare Company | Wound and therapy compress and dressing |
| CN104045674B (zh) * | 2014-05-21 | 2017-01-04 | 丽珠医药集团股份有限公司 | 一种阿奇霉素的制备方法 |
| CN105106109A (zh) * | 2015-09-11 | 2015-12-02 | 江苏锦宇环境工程有限公司 | 一种阿奇霉素缓释滴眼剂的制备方法 |
| CN108289908A (zh) * | 2015-12-22 | 2018-07-17 | 日油株式会社 | 泪液油层稳定剂及含有该泪液油层稳定剂的滴眼剂 |
| US12029681B2 (en) | 2016-03-01 | 2024-07-09 | The Hilsinger Company Parent, Llc | Therapeutic eye mask system |
| US12011388B2 (en) | 2016-03-01 | 2024-06-18 | The Hilsinger Company Parent, Llc | Therapeutic thermal compress with phase-change material |
| US12156831B2 (en) | 2016-03-01 | 2024-12-03 | The Hilsinger Company Parent, Llc | Therapeutic eye compress system |
| US9981041B2 (en) * | 2016-08-23 | 2018-05-29 | Ira Jason Salzman | Ophthalmic lubricating spray |
| USD844795S1 (en) | 2016-11-30 | 2019-04-02 | Bruder Healthcare Company, Llc | Therapeutic eye mask |
| USD871598S1 (en) | 2016-11-30 | 2019-12-31 | Bruder Healthcare Company, Llc | Therapeutic eye mask |
| CN109381707B (zh) * | 2017-08-03 | 2022-02-15 | 沈阳药科大学 | 一种阿奇霉素离子对脂质体滴眼液及其制备方法 |
| JP2023133646A (ja) * | 2020-06-26 | 2023-09-27 | 参天製薬株式会社 | 脂質分泌促進剤 |
| CA3199736A1 (en) | 2020-11-23 | 2022-05-27 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
| US20240050446A1 (en) * | 2021-02-25 | 2024-02-15 | Sun Pharmaceutical Industries Limited | Dexamethasone for treatment of blepharitis |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861411B1 (en) | 1997-12-02 | 2005-03-01 | Pfizer, Inc. | Method of treating eye infections with azithromycin |
| ATE319456T1 (de) | 1998-05-08 | 2006-03-15 | Univ Miami | Verwendung von tetracyclinen zur behandlung von störungen der meibomschen drüsen |
| US7056893B2 (en) | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
| US6239113B1 (en) | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
| US7063857B1 (en) | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
| IT1313610B1 (it) * | 1999-08-09 | 2002-09-09 | S I F I Societa Ind Farmaceuti | Processo per la preparazione di formulazioni acquose per uso oftalmico |
| AR031135A1 (es) | 2000-10-10 | 2003-09-10 | Upjohn Co | Composiciones de antibiotico topico para el tratamiento de infecciones oculares |
| HRP20010301A2 (en) * | 2001-04-27 | 2001-12-31 | Pliva D D | New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases |
| WO2004091436A2 (en) | 2003-04-15 | 2004-10-28 | The Regents Of The University Of California | Methods and compositions for treating ocular disease |
| US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
| US20050137205A1 (en) * | 2003-12-22 | 2005-06-23 | Van Breen Eduard T. | Formulation for treating periocular disease |
| US8425929B2 (en) | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
| WO2005110374A1 (en) | 2004-04-30 | 2005-11-24 | Allergan, Inc. | Intraocular drug delivery systems containing a therapeutic component, a cyclodextrin, and a polymeric component |
| US8372814B2 (en) | 2004-06-07 | 2013-02-12 | Ista Pharmaceuticals, Inc. | Ophthalmic formulations and uses thereof |
| US8349352B2 (en) | 2005-02-04 | 2013-01-08 | Auburn University | Therapeutic contact lenses with anti-fungal delivery |
| US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
| US7247623B2 (en) | 2005-08-19 | 2007-07-24 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with non-drying antihistamines |
| US20070105788A1 (en) * | 2005-11-09 | 2007-05-10 | Serena Mraz-Gernhard | Azithromycin for treatment of granulomatous rosacea |
| TWI435729B (zh) | 2005-11-09 | 2014-05-01 | Combinatorx Inc | 治療病症之方法,組合物及套組 |
| CA2635797C (en) | 2006-02-09 | 2015-03-31 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
| EP2364707B1 (en) * | 2006-08-07 | 2013-04-03 | Bausch & Lomb Incorporated | Compositions and methods for treating, controlling, reducing, or ameliorating infections and sequelae thereof |
| US11078262B2 (en) | 2007-04-30 | 2021-08-03 | Allergan, Inc. | High viscosity macromolecular compositions for treating ocular conditions |
| US20080286338A1 (en) | 2007-05-15 | 2008-11-20 | Boston Foundation For Sight | Drug delivery system with scleral lens |
| US8349806B2 (en) | 2008-07-10 | 2013-01-08 | Inspire Pharmaceuticals, Inc. | Method of treating blepharitis |
| US20100190734A1 (en) | 2009-01-23 | 2010-07-29 | Romulus Kimbro Brazzell | Method of treating dry eye disease with azithromycin |
-
2009
- 2009-07-10 US US12/501,316 patent/US8349806B2/en active Active
- 2009-07-10 MX MX2011000247A patent/MX2011000247A/es active IP Right Grant
- 2009-07-10 AU AU2009268372A patent/AU2009268372B2/en not_active Ceased
- 2009-07-10 WO PCT/US2009/050311 patent/WO2010006306A1/en not_active Ceased
- 2009-07-10 CA CA2730120A patent/CA2730120A1/en not_active Abandoned
- 2009-07-10 JP JP2011517670A patent/JP2011527709A/ja not_active Withdrawn
- 2009-07-10 EP EP09795262.6A patent/EP2313103B1/en not_active Not-in-force
-
2014
- 2014-09-18 JP JP2014190105A patent/JP2014240433A/ja not_active Ceased
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